Patents Assigned to Foundation
  • MEDIUM COMPRISING TRANSFORMING GROWTH FACTOR BETA 1 AND BASIC FIBROBLAST GROWTH FACTOR
    Publication number: 20190093078
    Abstract: The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.
    Type: Application
    Filed: September 3, 2018
    Publication date: March 28, 2019
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Michal AMIT, Joseph ITSKOVITZ-ELDOR
  • FORCE/TORQUE SENSOR THAT MINIATURIZATION IS AVAILABLE
    Publication number: 20190094085
    Abstract: A force/torque sensor includes a ground unit having an internal space, a sensor unit positioned within the internal space and including a plurality of electrodes generating capacitances with the ground unit, and a support unit combined with a portion of the ground unit and supporting the sensor unit.
    Type: Application
    Filed: March 16, 2018
    Publication date: March 28, 2019
    Applicant: Research & Business Foundation Sungkyunkwan University
    Inventors: Hyouk Ryeol CHOI, Ui Kyum KIM, Yong Bum KIM
  • Morphological cell parameter-based red blood cell test method and digital holographic microscope used therein
    Patent number: 10241469
    Abstract: Provided are a morphological cell parameter-based erythrocyte test method and digital holographic microscope used therein, and the morphological cell parameter-based erythrocyte test method includes performing modeling to create a 3D image of an erythrocyte to be tested and measuring morphological parameters of the erythrocyte based on the 3D image. The morphological cell parameter-based erythrocyte test method performs modeling of a 3D image for an erythrocyte to be tested and measures morphological parameters of the erythrocyte based on the 3D image. Therefore, time and effort consumed in measurement may be reduced, and accuracy of the measurement is excellent.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: March 26, 2019
    Assignee: Industry-Academic Cooperation Foundation, Chosun University
    Inventors: Inkyu Moon, Keyvan Jaferzadeh
  • Methods for combating bacterial infections by killing persister cells with mitomycin C and/or cisplatin
    Patent number: 10238689
    Abstract: The present disclosure provides a method for killing persister cells with mitomycin C and/or cisplatin, or derivatives thereof. Recalcitrant infections are difficult to treat due to persister cells, a subpopulation of all bacterial populations that is highly tolerant against all traditional antibiotics since the cells are dormant and antibiotics are designed to kill growing cells. Here, we show that MMC and cisplatin eradicate persister cells through a growth-independent mechanism, cross-linking DNA. We find both agents are effective against both planktonic cultures and highly robust biofilm cultures for a broad range of bacterial species, including commensal Escherichia coli K-12 as well as pathogenic species of E. coli, Staphylococcus aureus, and Pseudomonas aeruginosa. In certain approaches cisplatin is superior to MMC.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: March 26, 2019
    Assignee: The Penn State Research Foundation
    Inventors: Thomas Wood, Brian Kwan, Nityananda Chowdhury
  • Method and apparatus for transmitting/receiving signaling information in digital broadcast system
    Patent number: 10244275
    Abstract: The present invention relates to a method for transmitting signaling information in a digital broadcast system, the method comprising the steps of: adaptively generating a signaling table relating to signaling information transmitted from a data link layer on the basis of at least one structure among a hierarchical structure and a flat structure on the basis of a characteristic of service configuration; and transmitting the generated signaling table.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: March 26, 2019
    Assignees: Samsung Electronics Co., Ltd., Kyonggi University Industry & Academia Cooperation Foundation
    Inventors: Sung-Hee Hwang, Byoung-Dai Lee, Hyun-Koo Yang, Sung-Oh Hwang
  • Methods and compositions related to soluble monoclonal variable lymphocyte receptors of defined antigen specificity
    Patent number: 10239936
    Abstract: Disclosed are compositions and methods related to variable lymphocyte receptors (VLRs). More particularly, disclosed are a variety of antigen specific polypeptides, including soluble, monoclonal, and multivalent forms, as well as methods of using the polypeptides, antibodies that bind the antigen specific polypeptides, and nucleic acids, vectors and expression systems that encode the polypeptides. Antigen specific polypeptides that selectively bind pathogens, like anthrax, and carbohydrates, like blood group determinants, are specifically disclosed.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: March 26, 2019
    Assignee: The UAB Research Foundation
    Inventors: Max D. Cooper, Brantley R. Herrin, Matthew N. Alder
  • Smart water heater system, method and computer readable media
    Patent number: 10240816
    Abstract: A smart water heater system (SWHS) for a domestic water system having a plurality of fixtures has a water tank having a cold water inlet and a heat source configured to heat the cold water. The SWHS may also have a mixing valve to blend cold water with the hot water to produce blended water, wherein the blended water is directed to the domestic water system. The SWHS may have a controller in communication with the mixing valve configured to identify which fixture is being used when the domestic water system is drawing water from the water tank, determine an average water temperature utilized by each fixture, and adjust the mixing valve based on which fixture is identified such that a temperature of the blended water is generally equal to the average water temperature for the identified fixture.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: March 26, 2019
    Assignee: University of Virginia Patent Foundation
    Inventors: Cameron Dean Whitehouse, Md Anindya Tahsin Prodhan
  • Flexible biodegradable polymeric step-index optical fiber
    Patent number: 10241258
    Abstract: A biocompatible and biodegradable polymeric step-index optical fiber includes a core and a cladding around the core. The core is made from a core material fabricated by bonding a citric acid and at least a first monomer using a synthesis process. The cladding is made from a cladding material fabricated by bonding the citric acid and at least a second monomer using the synthesis process. The core has a refractive index higher than that of the cladding, while a difference between an initial modulus of the core and the cladding is preferably less than 30% and a difference between the biodegradation rates of the core and cladding is preferably less than 30% after about 4 weeks. Optical properties of the core and cladding are tunable by adjusting monomer ratios, choices of monomers or cross-linking degrees.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: March 26, 2019
    Assignee: The Penn State Research Foundation
    Inventors: Jian Yang, Zhiwen Liu, Dingying Shan, Chenji Zhang
  • Methods to identify soybean aphid resistant quantitative trait loci in soybean and compositions thereof
    Patent number: 10238062
    Abstract: The present invention is in the field of plant breeding and aphid resistance. More specifically, the invention includes a method for breeding soybean plants containing quantitative trait loci that are associated with resistance to aphids, Aphis glycines. The invention further includes method for monitoring the introgression quantitative trait loci (QTL) conferring aphid resistance into elite germplasm in a breeding program.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: March 26, 2019
    Assignees: Monsanto Technology LLC, University of Georgia Research Foundation, Inc.
    Inventors: Vergel Concibido, James Narvel, Jennifer Yates, Henry Roger Boerma
  • Soft tissue repair allografts and methods for preparing same
    Patent number: 10238485
    Abstract: Allografts for soft tissue repair, including breast reconstruction and other plastic surgery procedures, are disclosed. One allograft is made from decellularized dermal tissue and constitutes a collagen matrix having substantially uniform density and porosity. Another allograft is a hybrid bilayer tissue form that is made from decellularized dermal and adipose tissues. Methods for making both allografts are also disclosed.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: March 26, 2019
    Assignee: Musculoskeletal Transplant Foundation
    Inventors: Michael Locarno, Bryan J. Choi, Manh-Dan Ngo
  • Functionalized nanotube sensors and related methods
    Patent number: 10241078
    Abstract: Functionalized nanotube arrays, sensors, and related methods of detecting target compounds are presented. A functionalized nanotube array (235) can include a plurality of metal oxide nanotubes (240). The metal oxide nanotubes (240) can be formed of a metal oxide and can have an interior or exterior surface that is optionally functionalized with at least one metal ion. These metal nanotubes (240) can be used in a sensor (200) for detecting target compounds such as volatile organic compounds, and biomarkers in a fluid environment. The sensor (200) can further include a power source (245) configured to apply a voltage to the nanotube array (235) and a current sensor (250) configured to monitor and detect changes in a response current which varies upon binding with the target compounds.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: March 26, 2019
    Assignee: University of Utah Research Foundation
    Inventors: Swomitra Kumar Mohanty, Manoranjan Misra, Younghwan Kim, Jules Magda
  • Methods for reducing the occurrence of hot flashes
    Patent number: 10238629
    Abstract: The present invention provides methods to reduce the number and severity of hot flashes utilizing tocotrienols. In particular, symptoms of perimenopause and menopause may be treated using the present methods. The present invention also provides methods to increase tissue concentrations of tocotrienols.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: March 26, 2019
    Assignee: Ohio State Innovation Foundation
    Inventors: Chandan K. Sen, Sashwati Roy, Savita Khanna, Cameron Rink
  • Process for the production of shaped cellulose articles
    Patent number: 10240259
    Abstract: A method of manufacturing a cellulose-based shaped article. The method comprises subjecting a solution of lignocellulosic material, dissolved in a distillable ionic liquid, to a spinning method, wherein the ionic liquid is a diazabicyclononene (DBN)-based ionic liquid. DBN-based ionic liquids have good dissolution power, high thermal and chemical stability, lack runaway reactions and exhibit low energy consumption, due to low spinning temperatures. The shaped cellulose articles can be used as textile fibers, high-end non-woven fibers, technical fibers, films for packaging, and barriers films in batteries, as membranes and as carbon-fiber precursors.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: March 26, 2019
    Assignees: Aalto University Foundation sr, Helsingin Yliopisto
    Inventors: Anne Michud, Alistair W. T. King, Arno Parviainen, Herbert Sixta, Lauri Hauru, Michael Hummel, Iikka Kilpeläinen
  • Trimethylamine-containing compounds for diagnosis and prediction of disease
    Patent number: 10241093
    Abstract: The present invention provides markers and methods for determining whether a subject, particularly a human subject, has or is at risk of developing, a disease such as cardiovascular disease, diabetes mellitus, insulin resistance, metabolic syndrome, NAFLD (Nonalcoholic Fatty Liver Disease) or NASH (Nonalcoholic Steatohepatitis) (e.g., within the ensuing year, two years, and/or three years). The present application also relates to the use of such markers and methods for monitoring the status of such diseases in a subject or the effects of therapeutic agents on subjects with such diseases.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: March 26, 2019
    Assignee: The Cleveland Clinic Foundation
    Inventors: Stanley L. Hazen, Zeneng Wang, Bruce S. Levison
  • Apparatus and method for encrypting data in near field communication system
    Patent number: 10243730
    Abstract: A method for encrypting data in a near field communication system is provided. The method includes generating encrypted data based on first data input in a current state and second data input in a state immediately preceding the current state, and encoding the encrypted data through a predetermined error correcting code.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: March 26, 2019
    Assignees: Samsung Electronics Co., Ltd., Korea University Research and Business Foundation
    Inventors: Jun Heo, Kyoung-Hoon Kwon
  • Current reference based selective harmonic current mitigation pulsed width modulation
    Patent number: 10243446
    Abstract: Methods and apparatuses for selective harmonic current mitigation pulse width modulation (SHCM-PWM) are provided. Low switching frequencies can be utilized for grid connected cascaded H-bridge multilevel rectifiers to meet harmonic requirements within an extended harmonic spectrum. Instead of using voltage references to calculate switching angles for rectifiers as in conventional selective harmonic elimination-PWM (SHE-PWM) and selective harmonic mitigation-PWM (SHM-PWM), current references can be used to compensate for current harmonics and meet current harmonic requirements and total demand distortion (TDD) within the entire harmonic spectrum.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: March 26, 2019
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Shuo Wang, Amirhossein Moeini, Hui Zhao
  • N-carbamoylated urethane for treating a neuroinflammatory disease
    Patent number: 10238635
    Abstract: There is provided a composition for treating a neuroinflammatory disease comprising a N-carbamoylated urethane compound which has an effect of inhibiting the activity of microglia or astrocytes and the production of nitric oxide (NO) and TNF-?, and suppressing the expression of IL-1? And iNOS genes. There is also provide a method for treating a neuroinflammatory disease, the method comprising the step of administering a N-carbamoylated urethane compound. Due to its above mentioned effects, the N-carbamoylated urethane compound according to the present invention can be useful for the treatment of neuroinflammatory diseases.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: March 26, 2019
    Assignee: Kyungpook National University Industry-Academic Cooperation Foundation
    Inventors: Kyoungho Suk, Gyun Jee Song, Youngpyo Nam, Myungjin Jo
  • Flip-flop and driving method thereof
    Patent number: 10243567
    Abstract: A flip-flop includes a conditional boosting stage, a pulse generator and a latch. The conditional boosting stage includes a boosting capacitor, and is configured to pre-charge the boosting capacitor in accordance with a previous output signal and boost a node connected to the boosting capacitor upon a level the previous output signal being different from a level of a current input signal. The pulse generator is configured to generate a pulsed signal in accordance with transitions of a clock signal. The latch configured is to latch the current input signal to a current output signal in accordance with the pulsed signal.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: March 26, 2019
    Assignee: Research & Business Foundation Sungkyunkwan University
    Inventors: Bai Sun Kong, Ji Hoon Park
  • Micro- and nano-quantity sleep enhancing nutrient composition and method of enhancing central nervous system protein clearance using same
    Patent number: 10238684
    Abstract: The present invention relates to a dietary supplement, composition, nutraceutical, and/or system for inducing or treating biological responses or conditions (namely sleep or sleep disorders) which utilize ultra-low dosage amounts of vitamins, minerals, amino acids, co-enzymes, stimulants, and/or similar ingredients in a highly bio-active delivery system which bypasses first pass metabolism. In particular, the present invention relates to a nutraceutical composition/formulation which substantially bypasses first pass metabolism and such as, but not limited to, activation of the glymphatic system to facilitate clearance of neuronal metabolites from the CSF and interstitial fluids in the brain.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: March 26, 2019
    Assignee: Foundational BioSystems, LLC
    Inventor: Jon Scott Theus
  • Exercise bicycle handlebar grip extension
    Patent number: D844081
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: March 26, 2019
    Assignee: Foundation Fitness, LLC
    Inventor: Eric Golesh