Abstract: According to aspects illustrated herein, there are provided a sensor chip suitable for serological detection of Streptococcus pneumoniae, a method for detecting serotypes of Streptococcus pneumoniae using the sensor chip, a detection system that includes the sensor chip, and a method for detecting serotypes of Streptococcus pneumoniae using the detection system described herein.

Abstract: Provided herein are novel small-molecules that have use in the inhibition of Eis, which mediates kanamycin resistance in Mycobacterium tuberculosis. The presently-disclosed subject matter further includes a pharmaceutical composition including a small molecule inhibitor, as described herein, and a suitable pharmaceutical carrier. Methods of treating tuberculosis comprising administering to an individual an effective amount of the disclosed small molecule inhibitors to mediate kanamycin A resistance and treat tuberculosis are also provided.

Abstract: A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water nanoemulsion (NE) drug delivery system. A method of treating cancer by administering an effective amount of a pharmaceutical composition including a PUFA-taxoid conjugate encapsulated in an oil-in-water NE drug delivery system to a subject in need of treatment, and treating cancer. A method of overcoming multidrug resistance by exposing a multidrug resistant cell to an effective amount of a pharmaceutical composition including an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water NE drug delivery system, and inducing the death of the multidrug resistant cell. A method of eliminating a cancer stem cell. Methods of reducing stemness of a cancer stem cell, retaining drug in the body, and providing a slower release profile.

Abstract: The present invention relates to genetic analysis and evaluation utilizing copy-number variants or polymorphisms. The methods utilize array comparative genomic hybridization and PCR assays to identify the significance of copy number variations in a human or non-human animal subject or subject group.

Abstract: This disclosure relates to methods for promoting bone formation or reducing bone destruction. This disclosure also relates to methods for promoting the recruitment of mesenchymal stem cells (MSC) to a local site of injury or surgical intervention in bone to promote healing. In addition, this disclosure relates to methods for reducing or preventing mineral formation or bone growth, or reducing bone mass. The methods disclosed herein are useful for treating conditions such as osteoradionecrosis.

Abstract: A microfluidic detection system for micrometer-sized entities, such as biological cells, includes a detector component incorporating a plate with a plurality of opening, the plate separating two chambers, one in communication with a fluid source containing target entities bound to magnetic beads. The openings are sized to always permit passage of the magnetic beads therethrough into a lower one of the chambers and are further sized to always prevent passage of the target entities from the upper one of the chambers. The detector component further includes a magnet positioned to pull unbound magnetic beads through the openings and to capture target entities bound to magnetic beads on the surface of the plate. In a further feature, the microfluidic detection system is configured to pass target molecules through the plate to be bound to a functionalized surface of the lower chamber.

Abstract: In one aspect, the invention provides an implantable device comprising a uniform mixture of components including degradable polymer, inorganic bone particulate either natural or synthetic, a drug, and a soluble microporagen. In some embodiments, the uniform mixture further includes a soluble polymer macroporagen. In some embodiments, the uniform mixture is coated with an immobilized outer porous layer comprising or consisting of synthetic or natural inorganic bone granules. In further aspects, the invention provides an implantable device comprising a composite core of degradable polymer, bone, and a drug, and a coating comprising or consisting of microporous bone overlayer covering the degradable composite core.

Abstract: The present disclosure relates to a pre-5th-Generation (5G) or 5G communication system to be provided for supporting higher data rates Beyond 4th-Generation (4G) communication system such as long term evolution (LTE). According to various embodiments of the present disclosure, an apparatus according to aspects of a communication system that shares a channel with another communication system may include at least one processor and at least one transceiver. The at least one processor may be configured to determine a transmission timing of an initial signal based on a parameter for the initial signal that indicates that the apparatus occupies a channel and at least one detection interval for detecting a signal of the another communication system. The at least one transceiver is configured to transmit the initial signal according to the transmission timing.

Abstract: An overcoat that imparts a superhydrophobic surface to a painted surface of an object is a suspension of hydrophobic particles in a polymeric binder and a plasticizer in a solvent or mixed solvent. The particles are a metal oxide that is surface functionalized with a fluorinated alkyl silane or an alkyl silane. Surfaces coated using this paint display contact angles in excess of 150° and resist abrasion while retaining superhydrophobicity.

Abstract: Functionalized reduced graphene oxide (functionalized rGO), and a method of producing the same are provided. The functionalized reduced graphene oxide comprises reduced graphene oxide which is fluorinated and co-doped with at least one co-dopant selected from the group consisting of B, N and S.

Abstract: The present invention provides a solid dispersion of rufinamide in combination with a pharmaceutically acceptable carrier, process for its preparation and pharmaceutical compositions comprising it.

Abstract: Systems and methods are disclosed to downscale the resolution of a coarse-resolution soil moisture data. Coarse-resolution soil moisture data may include data cells that each represent a geographic region having at least one dimension greater than or equal to 1 km. A plurality of fine-resolution supplemental soil moisture data may be received that includes at least one of soil data, vegetation data, topography data, and climate data. The fine-resolution supplemental soil moisture data comprising data cells that each represent a geographic region having at least one dimension less than or equal to 100 meters. The coarse-resolution soil moisture data may be downscaled to fine-resolution soil moisture data using the plurality of fine-resolution supplemental soil moisture data, the fine-resolution soil moisture data comprising data cells that each represent a geographic region having at least one dimension less than 100 meters.

Abstract: This document relates to methods and materials for producing immune responses against polypeptides involved in antibiotic resistance. For example, vaccines against polypeptides involved in antibiotic resistance as well as methods for vaccinating mammals against polypeptides involved in antibiotic resistance are provided.

Abstract: The present disclosure provides a structure having a low reflectance surface, wherein the structure comprises: a base plate; and a plurality of inclined rods protruding from a first face of the base plate and inclined relative to a normal line to the first face, wherein the inclined rods are spaced from each other. Travel paths of light beams in the structure may be longer along the inclined rods. As a result, a larger amount of light may be absorbed by the structure having a low reflectance surface. The amount of light-beams as reflected from the structure having a low reflectance surface may be significantly reduced.

Abstract: A composition of matter includes a mixture of styrene derivative monomers and methacrylate/acrylate derivative monomers, which form hydrogen bonds between/among different precursors, and initiators, and the compositions are used to achieve composition control of the forming polymer, with the mole fraction of acrylate/methacrylate and styrene moieties in the forming polymer determined preferably by the monomer reactivity and monomer composition rather than the viscosity of the monomers.

Abstract: The present disclosure provides co-cultures of human pluripotent stem cell derived hepatocytes and at least one non-parenchymal cell population in vitro, methods of preparing the co-cultures and methods of using the co-cultures for high throughput screening and evaluation of drug candidates. The stem cell derived hepatocyte co-culture system provides an in vitro model in which cell viability and relatively mature hepatocyte phenotype of stem cell derived hepatocytes are maintained for extended periods relative to conventional monoculture.

Abstract: A vibration control system for an unmanned aerial vehicle (UAV) is disclosed. The system includes a base platform fixedly coupled to a UAV structure, a working platform coupled to the base platform by two or more cables at two or more connection points on the working platform, and two or more actuators positioned either on the base platform or the working platform, each actuator configured to receive a signal to adjust tension in a corresponding cable, wherein by adjusting tension in the two or more cables, natural frequency of the working platform can be adjusted in response to frequency of vibration experienced by the working platform in order to maintain a frequency ratio (FR) of the vibration frequency to the natural frequency at or above a predetermined value.

Abstract: The present invention relates to a new alga having an improved ability to produce a pigment, and when a mutant of the present invention is used, a carotenoid-based pigment, specifically, a xanthophyll can be produced by consuming less energy, so that it is possible to efficiently produce the pigment at the industrial level. Further, the pigment can be applied as a raw material for a food, a health functional food and a medicine, which include the pigment. In particular, since a DNA fragment is not likely to be inserted into a target base sequence or a base sequence other than the target, it is expected that the procedure of constructing the mutant is not regulated as a GMO, so that it is expected that the procedure of constructing the mutant can create a big economic effect in terms of an industry which produces lutein and zeaxanthin by using microalgae.

Abstract: The current invention is a method and system for optimally isolating adult derived stem cells from whole blood and reintroducing the adult derived stem cells into a subject at specific target areas having damaged tissue to be repaired.

Abstract: The present invention relates to a method for preparing superabsorbent polymer that has antibacterial activity, in which the basic properties of superabsorbent polymer are maintained or improved, and may exhibits excellent bacterial proliferation inhibition effect, and superabsorbent polymer prepared thereby. The preparation method of superabsorbent polymer comprises the steps of: forming base polymer powder using hydogel polymer comprising crosslinked polymer, and then, surface crosslinking the base polymer powder using a surface crosslinking solution comprising a surface crosslinking agent and cuprous oxide, wherein the cuprous oxide is included in the content of 0.001 to 2.5 parts by weight, based on 100 parts by weight of the base polymer powder.