Abstract: The disclosure provides for compositions and methods for the preservation of meat tissues, including fish, beef, poultry and pork, and meat analogs containing added heme protein, using very low amounts of phospholipase A2 (PLA2) enzymes in a combination with rosemary.
Type:
Application
Filed:
April 17, 2017
Publication date:
February 14, 2019
Applicant:
Wisconsin Alumni Research Foundation
Inventors:
Mark P. RICHARDS, Jie YIN, Wenjing ZHANG
Abstract: An integrated circuit chip with reverse engineering prevention includes: a signal generator part configured to generate a first signal; a metal line part configured to receive the first signal generated at the signal generator part and generate a second signal; a comparison logic part configured to compare the first signal generated at the signal generator part and the second signal generated at the metal line part; and a signal routing part formed on both sides of the metal line part to connect the signal generator part with the metal line part at one side and connect the metal line part with the comparison logic part at the other side, where the signal routing part is a shift register.
Type:
Grant
Filed:
July 5, 2017
Date of Patent:
February 12, 2019
Assignee:
Korea University Research and Business Foundation
Abstract: Methods for improving an inflammatory disorder in a subject are provided. Methods include positioning a therapy delivery device on a neural target site that contributes to immune activity of the subject. The therapy delivery device is activated to deliver a therapy signal to the neural target site to improve the subject's inflammatory disorder.
Type:
Grant
Filed:
December 19, 2016
Date of Patent:
February 12, 2019
Assignee:
Ohio State Innovation Foundation
Inventors:
Jan Schwab, Phillip Popovich, Ali R. Rezai
Abstract: This document provides polymer compositions (e.g., biopolymer compositions) and coatings. For example, methods and materials related to polymer compositions (e.g., biopolymer compositions) and coatings as well as methods and materials for making and using such compositions (e.g., biopolymer compositions) and coatings are provided.
Type:
Grant
Filed:
July 15, 2014
Date of Patent:
February 12, 2019
Assignee:
The Penn State Research Foundation
Inventors:
Jeffrey M. Catchmark, Adam Ross Plucinski
Abstract: The present invention relates to a method for manufacturing a module type microfluidic chip comprising: (a) printing electrode patterns on a substrate using a conductive ink and inkjet printing; (b) cutting the printed electrode patterns; and (c) assembling the cut electrode patterns to manufacture the module type microfluidic paper chip. Unlike the traditional method for manufacturing printed circuit substrate using a patterning agent or device, the method of the present invention only incorporates a simple printing process using an inkjet printer, and thus patterning can be simplified and various types of chips can be manufactured depending on the assembly type of electrode patterns. Accordingly, inexpensive, economical, and highly utilizable microfluidic chips can be provided using the method of the present invention.
Type:
Grant
Filed:
May 2, 2013
Date of Patent:
February 12, 2019
Assignee:
Industry-University Cooperation Foundation Sogang University
Inventors:
Kwan Woo Shin, Hyo Jin Ko, Oh-Sun Kwon, Jae Hak Choi, Byeong No Lee, Ju Mi Lee
Abstract: The present invention relates to compositions for and methods of optically imaging tissues or cells using imaging agents having desirable in vivo properties that result in improved signal-to-background ratio.
Type:
Grant
Filed:
June 26, 2017
Date of Patent:
February 12, 2019
Assignees:
Beth Israel Deaconess Medical Center, Inc., Georgia State University Research Foundation Inc.
Abstract: Methods for producing new neurons in the brain in vivo are provided according to aspects of the present invention which include introducing NeuroD1 into a glial cell, particularly into a reactive astrocyte or NG2 cell, thereby “converting” the reactive glial cell to a neuron. Methods of producing a neuronal phenotype in a glial cell are provided according to aspects of the present invention which include expressing exogenous NeuroD1 in the glial cell, wherein expressing exogenous NeuroD1 includes delivering an expression vector, such as a viral expression vector, including a nucleic acid encoding the exogenous NeuroD1 to the glial cell.
Type:
Grant
Filed:
July 6, 2017
Date of Patent:
February 12, 2019
Assignee:
The Penn State Research Foundation
Inventors:
Gong Chen, Lei Zhang, Zheng Wu, Yuchen Chen, Fan Wang, Ziyuan Guo
Abstract: Compositions and methods for preventing and treating Neisseria gonorrhoeae infection with AR-12 alone or in combination with antibiotics are provided.
Type:
Grant
Filed:
September 26, 2016
Date of Patent:
February 12, 2019
Assignees:
Research Institute at Nationwide Children's Hospital, Ohio State Innovation Foundation
Abstract: A method of forming a spectral selective coating is disclosed. The method may include providing particles on a substrate, wherein the particles include submicron particles. The method may farther include sintering the particles under atmospheric pressure to form a sintered layer an the substrate and texturing the sintered layer to provide a submicron surface roughness height on the sintered layer.
Type:
Grant
Filed:
August 11, 2015
Date of Patent:
February 12, 2019
Assignee:
University of Virginia Patent Foundation
Abstract: An introduction arrangement for a fenestrated or branched stent graft (13) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer (1) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator (11) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath (15) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter (21) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire (29) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.
Type:
Grant
Filed:
September 20, 2017
Date of Patent:
February 12, 2019
Assignees:
Cook Medical Technologies LLC, The Cleveland Clinic Foundation
Inventors:
David Ernest Hartley, John Lennon Anderson, Roy K. Greenberg, Wolf Stelter
Abstract: A hydrogen sensor includes a hydrogen-sensing unit and a transistor connected to the hydrogen-sensing unit. The hydrogen-sensing unit includes a substrate made of an elastic material, a thin film made of transition metal or alloy thereof, disposed on the surface of the substrate and having a plurality of nanogaps formed therein, and an electrode formed on the thin film. The hydrogen-sensing unit is connected with a source (or drain) or a gate of the transistor via a connector.
Type:
Grant
Filed:
September 30, 2014
Date of Patent:
February 12, 2019
Assignee:
Industry-Academic Cooperation Foundation, Yonsei University
Abstract: A semiconductor stacking structure according to the present invention comprises: a monocrystalline substrate which is disparate from a nitride semiconductor; an inorganic thin film which is formed on a substrate to define a cavity between the inorganic thin film and the substrate, wherein at least a portion of the inorganic thin film is crystallized with a crystal structure that is the same as the substrate; and a nitride semiconductor layer which is grown from a crystallized inorganic thin film above the cavity. The method and apparatus for separating a nitride semiconductor layer according the present invention mechanically separate between the substrate and the nitride semiconductor layer. The mechanical separation can be performed by a method of separation of applying a vertical force to the substrate and the nitride semiconductor layer, a method of separation of applying a horizontal force, a method of separation of applying a force of a relative circular motion, and a combination thereof.
Type:
Grant
Filed:
July 13, 2015
Date of Patent:
February 12, 2019
Assignee:
Seoul National University R&DB Foundation
Abstract: A shape-memory self-healing polymeric network (SMSHP) is useful as a molded part, a coating, or as a matrix for a composite that can be repaired by heating to a controlled temperature. The SMSHP has thermally reversible repeating units where a thermally reversible adduct is situated between two common linking units formed during a polymerization process between thermally reversible monomers and cross-linking monomers. Optionally, other repeating units can be present from other monomers. Shape-memory results when the SMSHP is warmed to a temperature in excess of its glass transition temperature and self-healing then proceeds when a higher temperature is achieved where thermally reversible adducts dissociates to complementary groups that subsequently reform the adduct without distortion of the memorized shape. The thermally reversible adducts can be Diels-Alder (DA) adducts in a polyurethane, poly urea, or amine epoxy SMSHP network.
Type:
Grant
Filed:
May 18, 2016
Date of Patent:
February 12, 2019
Assignee:
University of Florida Research Foundation, Inc.
Abstract: A method and device for harvesting and storing solar energy is provided. The device converts solar energy to electrical energy via the photovoltaic effect. The device includes a pair of electrodes, at least one of which is transparent to allow solar energy to pass through. A medium is disposed between the electrodes which exhibits a combination of photovoltaic and ferroelectric properties. When solar energy passes through the transparent electrode and is received by the medium, electron-hole pairs establish a voltage potential between electrodes in the device via the photovoltaic effect. The voltage potential may be retained and the mobile charge may be stored in the absence of solar energy via the ferroelectric effect.
Abstract: Multigraft copolymers having various structures, e.g., comb and centipede structures, can be prepared from emulsion copolymerization of monomers and macromonomers. The emulsion copolymerization can be initiated by a thermally activated radical initiator or a redox initiation system. The multigraft copolymers can have high molecular weight and/or a large number of branch points. Elastomer or adhesive compositions of the copolymers can be prepared. Also described are poly(n-alkyl acrylate-graft-styrene) multigraft copolymers.
Type:
Grant
Filed:
June 19, 2015
Date of Patent:
February 12, 2019
Assignee:
University of Tennessee Research Foundation
Inventors:
Jimmy W. Mays, Nam-Goo Kang, Qiuyu Zhang, Wenwen Wang
Abstract: This document relates to methods and materials for reducing the risk of infection after a shoulder surgery or medical procedure. For example, this document relates to methods and materials for using a topical composition containing clindamycin or erythromycin to reduce the risk of or to prevent infection associated with shoulder surgeries or medical procedures.
Type:
Grant
Filed:
September 8, 2017
Date of Patent:
February 12, 2019
Assignee:
Mayo Foundation for Medical Education and Research
Abstract: This document provides methods and materials involved in identifying mammals having lung adenocarcinoma characterized by neuroendocrine differentiation as well as methods and materials involved in treating mammals having lung adenocarcinoma characterized by neuroendocrine differentiation. For example, methods and materials for using ASCL1 and RET expression levels to identify lung cancer patients having lung adenocarcinoma characterized by neuroendocrine differentiation are provided.
Type:
Grant
Filed:
March 10, 2017
Date of Patent:
February 12, 2019
Assignee:
Mayo Foundation for Medical Education and Research
Inventors:
Farhad Kosari, George Vasmatzis, Marie-Christine Aubry, Cristiane M. Ida
Abstract: A method of determining the stage (gestation) of a pregnancy—comprising the steps of quantifying the amount of the hormone hPL or a fragment thereof in a body fluid sample derived from a human female selected from a blood, plasma, serum and/or urine sample, and establishing the stage of pregnancy corresponding thereto. The disclosure also extends to a device adapted to detect the levels/amount of hPL or a fragment thereof in a body fluid sample, derived from a human female, selected from a blood, plasma, serum and/or urine sample, for establishing the stage of pregnancy.
Type:
Grant
Filed:
March 7, 2014
Date of Patent:
February 12, 2019
Assignees:
Guy's and St. Thomas's NHS Foundation Trust