Abstract: The present invention provides a pharmaceutical composition or a cosmetic product which can accelerate production of ceramide in cells. The ceramide production-accelerating agent contains a plant selected from the group consisting of Radix Heraclei Scabridi, Rhizoma Dioscoreae, Radix Rehmanniae, Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Radix Et Rhizoma Rhei, Pseudobulbus Bletillae, Radix Polygoni Multiflori, Radix Platycodi, and Herba Leonuli, or an extract thereof as an active ingredient. Further, the present invention provides a moisturizing agent containing a plant selected from the group consisting of Herba Leonuri and Rhizoma Dioscoreae, or an extract thereof as an active ingredient.

Abstract: The present invention relates to the technical field of measuring light source, specifically, to the method for measuring the luminous flux of LED. In the present invention, a reflecting cup is used as a collector of the luminous flux of LED. The collector has two sectional openings in the direction perpendicular to the symmetric axis thereof, which are positioned in the front and in the rear respectively, one of them positioned at the bottom end of the collector and having a smaller radius is used to input the light emitted by LED to be measured, the other positioned in the front end of the collector and having a larger radius is used to output the light to the detector placed in this position. Specifically, LED is fixed at the bottom end of the collector with a fixture, the light emitted by LED is directed toward the large opening of the collector, and the photometer is fixed closely at the large opening of the collector to receive light signals.

Abstract: An ion trap mass analyzer includes an elongated tunnel that has a wall, a longitudinal axis and an inner space. The wall includes a substrate and conductor trace patterns. There is also a variable electric potential means for providing electric potentials which is connected to the conductor trace patterns. The conductor trace patterns and the variable electric potential means provide a variable electric field within the inner space of the tunnel for transferring, storing, and analyzing ions.

Abstract: A high solid polyester polyol/silica nanocomposite resin with low viscosity is synthesized by an in situ polymerization method, namely conducting condensation polymerization of polyol/diacid monomer with a molar ratio of 1.1˜1.5 in the presence of colloidal silica nanoparticles with a diameter of 10˜150 nm. The resulted nanocomposite resins has a solid content of >95%, molecular weight of 1000˜5000 g/mol and hydroxyl value of 80-200 mg KOH/g, and a viscosity in the range of 800-2000 mPa.s. The viscosities are especially lower than those obtained by a blending method. The nanosilica content in the nanocomposite resin is 1˜15% (based on the total solid content of nanocomposite resin). The high solid polyester polyol/silica nanocomposite resin was curable with isocyanate or melamine to prepare high solid transparent nanocomposite coatings with obviously improved abrasion and scratch resistance, hardness, weatherability etc.

Abstract: The present invention belongs to the field of molecular biology. Specially, the invention relates to the screenings of a new drug target, a vaccine antigen and a test target of anti-tuberculosis treatment. Specially, based on the differential proteome technology and by the techniques of gene sequencing, in vitro protein expression, immunological detection and gene recombination, the invention primarily certifies that the up-regulated expression of Protein Rv2629 and the mutation of Gene 191A/C of Mycobacterium tuberculosis are related to the Rifampicin (RFP) drug-resistance, which provides useful information for the drug-resistance detection of Mycobacterium tuberculosis, the novel drug design and the vaccine development. Firstly, the drug-resistant strains are cultured and the proteins from drug resistance strains and sensitive strains are isolated respectively.

Abstract: The present invention relates to the biotechnology field, more particularly, to novel recombinant staphylokinase (RGD/KGD-Sak) derivatives and the preparation the thereof. The derivatives, have a low polymerizing ability, low immunogenicity and a bifunctionality of thrombolytics and anticoagulant. Based on the trimensional structural analysis of the monomer and dimer of recombinant staphylokinases and their biochemical properties, we designed two novel bifunctional staphylokinase molecular structures. Mutant genes were constructed by PCR site-directed mutagenesis, which were then recombined with a prokaryotic vector and used to transform E. coli. Engineered strains with a high expression level were selected by screening and propagated by fermentation, followed by disruption of the cells, centrifugation to collect inclusion bodies, renaturation, and purification of RGD/KGD-SAK through a two-step method. After lyophilized, the polymerizing ability and immunogenicity of the products decreased significantly.

Abstract: The present invention provides a thermosensitive and biodegradable microgel and a method of synthesizing such microgels. The thermosensitive and biodegradable microgel is synthesized from a macromer comprising a thermosensitive block polymer co-polymerized with a biodegradable moiety encapped with a cross-linkable or polymerizable moiety at either end. The microgels of the present invention are synthesized by inverse suspension polymerization of the macromers. The microgels are biodegradable into components that are non-toxic and easily removed from the body. The microgel of the present invention is temperature sensitive and is “intelligent” as well as biodegradable. The microgels are preferably used for the controlled release of a drug or in tissue engineering. Most preferably, the microgels are suitable for the control release of biologically active substances such as proteins.

Abstract: The present invention relates to the preparation ad application of a high-sensitive electrochemical luminescent composite material which has anti-biofouling properties useful as a sensor material. This material is prepared by immobilization of electrochemical luminescent material into polymer containing phospholipid groups, wherein, the electrochemical luminescent material including ruthenium complex, osmium complex, etc.; the phospholipid containing polymer is the copolymer of 2-methacryloyloxyethyl phosphorylcholine (MPC) and other polymerisable monomers. Animal experiment results revealed that this composite material has good anti-biofouling properties; it can be used in producing various sensors for bio-related detections.

Abstract: A compound having the following Formula: wherein R1, R2, Z, and Y are defined herein, and methods of preparation and application for treating mental disorders and inflammation are provided therewith.

Abstract: The invention belongs to the field of biological engineering techniques and relates to a thermophilic alkaline phosphoesterase. The invention provides an amino acid sequence of a thermophilic alkaline phosphoesterase of the invention, as well as a DNA fragment encoding the amino acid sequence. The present invention also includes methods for cloning an expression vector containing the DNA fragment or a portion thereof and for producing the recombinant enzyme. The invention also relates to a method for tagging biological macromolecules utilizing the enzyme.

Abstract: The present invention relates to folic acid-polysaccharide complexs and method of preparation thereof, more particularly relates to folic acid-Dextran complexs, method of preparation thereof, pharmaceutical compositions having said complex as active component and uses of said composition in therapy of tumors. The folic acid-polysaccharide complexs of the present invention have general formula of: (X)n—Y, wherein X is identical or different, and is selected from folic acid, derivatives of folic acid and other substances that can enter into cell via the pathway of folic acid receptor; Y is polysaccharide; n≧1.

Abstract: The invention relates to a novel member LYC1 of lysozyme gene family. The invention provides the cDNA sequence encoding for the novel lysozyme, the polypeptide encoded by the sequence, as well as the method for producing the novel human lysozyrne utilizing recombinant technology. The invention also provides the use of the novel human lysozyme.

Abstract: The present invention discloses an amorphous alloy catalyst containing boron, which is composed of a porous carrier, a Q-B amorphous alloy, and a metal additive (M), the content of Q-B amorphous alloy together with metal additive is from 0.1 to 60 wt %, based on the total weight of the catalyst, in which the atomic ratio (Q+M)/B is 0.5-10, and the Q/M atomic ratio is 0.1-1000; wherein Q represents an metal selected from group VIII and B represents boron; and said metal additive (M) refers to those one or more metal elements which can be reduced to its/their elemental states from the corresponding salts by a solution containing BH.sub.4.sup.- with the exception that M is not the one which is used as Q. Said catalyst exhibits high catalytic hydrogenation activity.

Abstract: The invention includes a method for obtaining an exact electrostatic quadrupole field by the use of simple structures having high resistance materials of uniform or continuously varied thickness to form closed boundaries. The potential of these boundaries is continuously varied with respect to position in accordance with specified design criteria. The method and structures can be used in electron optical systems and related scientific instruments.