Abstract: A method for preparing an ordered cross-stacked metal oxide nanowire array is provided. The method includes the following steps: conducting synthesis by using an amphiphilic diblock copolymer as a structure directing agent, tetrahydrofuran (THF) as a solvent and polyoxometalates (POMs) as an inorganic precursor, where the diblock copolymer can interact with POMs via an electrostatic force to form a core-shell cylindrical micelle in the solvent, which self-assembles to form an ordered multilayer-crossed organic-inorganic composite nanostructure during an evaporation process; the template is removed by calcination in air, thereby obtaining ordered and crossed metal oxide nanowires with various elements doping. The nanowire array material has a high specific surface area, a high crystallinity, and realizes uniform doping of heteroatoms.

Abstract: The present disclosure provides an omnidirectional beamforming method. In the omnidirectional beamforming method, a space-time block coding is performed on a data stream to be sent to obtain the coded data stream. Omnidirectional beamforming matrices corresponding to a uniform rectangular antenna array are constructed. The beamforming is performed on the coded data stream through the omnidirectional beamforming matrices, to generate a signal to be sent of the uniform rectangular antenna array.

Abstract: This application relates to biological pharmacy and biochemical engineering, and more particularly to a method of preparing a (S)-1-benzyl-1,2,3,4,5,6,7,8-octahydroisoquinoline compound. This method includes: subjecting a 1-benzyl-1,2,3,4,5,6,7,8-octahydroisoquinoline raceme as a substrate to selective oxidation in the presence of a monoamine oxidase and the non-selective reduction to prepare the (S)-1-benzyl-1,2,3,4,5,6,7,8-octahydroisoquinoline compound, where the monoamine oxidase has an amino acid sequence as shown in SEQ ID NO: 1 or an amino acid sequence having an identity of more than 80% with SEQ ID NO: 1. The kinetic resolution is carried out in the presence of the monoamine oxidase as a catalyst and a reductant, and the resulting product has a high chiral purity.

Abstract: The present disclosure relates to a non-volatile ferroelectric memory and a method of preparing the same. The ferroelectric memory includes a ferroelectric storage layer, a first electrode and a second electrode; the first electrode and the second electrode each include a buried conductive layer formed by patterning in a surface of the ferroelectric storage layer and an electrode layer formed on the buried conductive layer; and when a write signal in a certain direction is applied between the first electrode and the second electrode, the electric domains of a part of the ferroelectric storage layer between a pair of the buried conductive layers are enabled to be reversed, so that a domain wall conductive passage that electrically connects the first electrode and the second electrode can be established.

Abstract: A portable liquid collection device includes a liquid collector, a guide tube and a liquid collection tube. The liquid collector includes a flowing liquid hole and an anti-slip structure. The guide tube includes two ends, one end connects to the liquid collector, and the other end is in a needle-shaped structure and connects to the liquid collection tube. A gas channel and a liquid channel are disposed in a tube body of the guide tube. The guide tube is provided with an outer annular structure. The liquid collection tube includes a collection tube body and a collection tube cover. The collection tube cover includes a tube cover body and a blocking plug. A placing slot for placing the blocking plug is disposed between the top and the bottom of the tube cover body.

Abstract: The present invention discloses a method for preparing aldehydes or ketones via aerobic oxidation of alcohols with the copper salts and nitroxide radicals as catalysts. Both oxygen and air could be used as oxidants, after 4 to 48 hours of reaction in an organic solvent at room temperature, the alcohols are efficiently oxidized to the corresponding aldehydes or ketones. The present invention has the following advantages: easy to operate, refraining from using chlorides which are corrosive to equipment, readily available raw materials and reagents, mils reaction conditions, the broad substrate scope, good functional group tolerance, convenient purification, environmentally friendly and no pollution. Thus, the method is suitable for industrial production.

Abstract: A method and a device for protein sequence analysis, and the use of microdroplets for improving protein sequencing by accelerating enzymatic digestion, wherein the method comprises the following steps: a) forming a solution containing protein into microdroplets having a size small enough to result in acceleration of protein digestion; b) introducing the microdroplets into a mass spectrometer (MS) for real-time detection; c) obtaining analysis result of the protein from the mass spectrometer (MS); wherein the protein is fully digested in the microdroplets before entering the mass spectrometer (MS). The method and device can achieve simple and nearly complete protein digestion in a very short time and obtain high sequence coverage.

Abstract: A method for synthesizing 2-(1-cyclohexenyl)ethylamine. Cyclohexanone (II) is reacted with a Grignard reagent in a first organic solvent to produce 1-vinylcyclohexanol (III), which is then subjected to chlorination and rearrangement reaction with a chlorinating reagent in a second organic solvent in the presence of an organic base to synthesize (2-chloroethylmethylene)cyclolxane (IV). Then (2-chloroethylmethylene)cyclohexane (IV) and urotropine are subjected to quaternization in a third organic solvent to synthesize N-cyclohexylidene ethyl urotropine hydrochloride (V). Finally, the N-cyclohexylidene ethyl urotropine hydrochloride (V) undergoes hydrolysis and rearrangement reaction in a solvent in the presence of an inorganic mineral acid to synthesize 2-(1-cyclohexenyl)ethylamine (I).

Abstract: Systems and methods for video backdoor attack include a trigger generation module for generating a universal adversarial trigger pattern specific to a task, an adversarial perturbation module for producing videos with manipulated features; and a poisoning and inference module for injecting the generated trigger into perturbed videos as poisoned samples for training; wherein the trigger pattern is patched and optimized on videos from all non-target classes but relabeled to a target class, and the trigger pattern is a universal adversarial trigger pattern generated by minimizing the cross-entropy loss.

Abstract: The present invention discloses a method for directly constructing highly optically active tetrasubstituted allenic acid compounds, i.e., a one-step process for directly constructing highly optically active axially chiral tetrasubstituted allenic acid compounds by using tertiary propargyl alcohol, carbon monoxide and water as reactants in an organic solvent in the presence of palladium catalyst, chiral diphosphine ligand, monophosphine ligand and organic phosphoric acid. The method of the present invention has the following advantages: operations are simple, raw materials and reagents are readily available, the reaction conditions are mild, the substrate has high universality, the functional group has good compatibility, and the reaction has high enantioselectivity (90%˜>99% ee).

Abstract: The present disclosure belongs to the field of pharmaceutical preparations and relates to the design of a series of lipophilic derivatives by using wild-type penetrating peptide penetratin. These penetratin derivatives have a strong ability to penetrate the ocular tissues and do not cause ocular tissue toxicity. As ocular absorption enhancers, non-invasive routes could be used to achieve intraocular drug delivery and increase the ocular bioavailability of drugs. These penetratin derivatives and the ophthalmic drug delivery system constructed by them are used for eye drop administration, which could replace the intraocular injection with poor patients compliance, which greatly enhances the convenience and safety of the treatment of intraocular and fundus diseases.

Abstract: The present invention provides recombinant monoclonal antibodies that bind to the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2 or COVID-19) spike protein, and methods of use. In various embodiments of the invention, the antibodies are fully human antibodies that bind to SARS-CoV-2 spike protein. In some embodiments, the antibodies of the invention are useful for inhibiting or neutralizing SARS-CoV-2 activity, thus providing a means of treating or preventing COVID-19 infection in humans. In some embodiments, the invention provides for a combination of one or more antibodies that bind to the SARS-CoV-2 spike protein for use in treating COVID-19 infection. In certain embodiments, the one or more antibodies bind to distinct non-competing epitopes comprised in the receptor binding domain of the SARS-CoV-2 spike protein.

Abstract: A portable liquid collection device includes a liquid collector, a guide tube and a liquid collection tube. The liquid collector includes a flowing liquid hole and an anti-slip structure. The guide tube includes two ends, one end connects to the liquid collector, and the other end is in a needle-shaped structure and connects to the liquid collection tube. A gas channel and a liquid channel are disposed in a tube body of the guide tube. The guide tube is provided with an outer annular structure. The liquid collection tube includes a collection tube body and a collection tube cover. The collection tube cover includes a tube cover body and a blocking plug. A placing slot for placing the blocking plug is disposed between the top and the bottom of the tube cover body.

Abstract: Disclosed is an integrated circuit for ferroelectric memory, the integrated circuit comprising: a ferroelectric memory array having a storage unit array formed on a ferroelectric single-crystal layer, wherein each ferroelectric memory unit in the ferroelectric memory array is at least formed by one storage unit in the storage unit array, or at least formed by one storage unit in the storage unit array and one transistor formed on a silicon substrate of a silicon-based reading and writing circuit that is electrically connected to the storage unit.

Abstract: The present invention provides an application of N-benzyl tryptanthrin derivative as tryptophan dioxygenase (TDO) inhibitor, and more specifically an application of N-benzyl tryptanthrin derivative or a pharmaceutically acceptable salt thereof. Said derivative has a structural general formula as represented by formula 1, wherein each group is defined as in the specification. The derivative of the present invention has a good TDO inhibiting activity and can be used to prepare a treatment for diseases associated with TDO activity and expression.

Abstract: The present invention belongs to the technical field of organic supermolecules, and specifically discloses a 3,4-ethylenedioxythiophene (EDOT) polymer capable of supramolecular assembly with carbon-based materials, and a preparation method thereof The polymer of the present invention is a polymer with 3,4-ethylenedioxythiophene-2-acetylene as the main chain and alkoxy as the side chain. The polymer is prepared as follows: subjecting EDOT to bromination, to give 2,5-dibromo-3,4-ethylenedioxythiophene; then reacting 2,5-dibromo-3,4-ethylenedioxythiophene and trimethylsilyl acetylene (TMSA) to give bis(trimethylsilyl)-3,4-ethylenedioxythiophene; removing trimethylsilyl (TMS) protecting groups from the bis(trimethylsilyl)-3,4-ethylenedioxythiophene, and subjecting the obtained compound and 2,5-dibromo-3,4-ethylenedioxythiophene to Sonogashira coupling to give an EDOT polymer.

Abstract: A network for image processing is provided, and more particularly, for coarse-to-fine recognition of image processing.

Abstract: This present disclosure describes a method, a device, and a system for performing a pulse shaping method that accurately converts short laser pulses into arbitrarily programmable optical waveforms with much longer duration. The optical pulse shaping method is based on multi-frequency acoustic-optic modulation and retro-diffraction based multiple optical delay line generation. Regarding the optical pulse shaping method, precise high-speed programming control on amplitudes, phases, and delays of a picosecond ultrashort sub-pulse sequence is implemented, to obtain an arbitrary waveform optical pulse with a near-THz bandwidth and a coherence time up to nanoseconds, for applications in quantum control of atomic/molecular optical transition.

Abstract: An erythropoietin-derived peptide having an amino acid sequence as shown in SEQ ID NO: 1. A method for preparing the above-described erythropoietin-derived peptide. Also provided is the use of the above-described erythropoietin-derived peptide for the preparation of a medicament for treating nerve cell damage. Also provided is the use of the above-described erythropoietin-derived peptide for the preparation of a medicament for treating hypoxic brain damage. Also provided is the use of the above-described erythropoietin-derived peptide for the preparation of a medicament for treating epilepsy. The novel EPO-derived peptide of the present invention has a small molecular weight and can penetrate the blood-brain barrier. Moreover, it is a small-molecule polypeptide derived from a functional protein in the human body, having an extremely small side effect to the human body compared with other developed and synthesized drugs, thereby it has a good clinical application prospect.

Abstract: A multi-level cell thin-film transistor memory and a method of fabricating the same, a structure of which memory comprises sequentially from down to top: a gate electrode, a charge blocking layer, a charge trapping layer, a charge tunneling layer, an active region, and source and drain electrodes; wherein the charge tunneling layer fully encloses the charge trapping layer so as to completely isolate the charge trapping layer from the ambience, which prevents change of physical properties and chemical compositions of the charge trapping layer during the annealing treatment, reduces loss of charges stored in the charge trapping layer, and enhances data retention property and device performance stability; a metal oxide semiconductor thin film is utilized as the charge trapping layer of the memory, which implements multi-level cell storage and improves storage density.