Patents Assigned to GEORGE MASON INTELLECTUAL PROPERTY
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Patent number: 7907132Abstract: An egocentric display that corresponds to a multidimensional frame of reference. The multidimensional frame of reference may include an ego center, a nadir below the ego center, and a zenith above the ego center. The egocentric display includes a center point, an inner concentric circle and an outer concentric circle. The center point represents the nadir. The inner concentric circle is centered about the center point and represents a horizon plane that is perpendicular to a zenith-nadir line that passes through the zenith, the ego center, and the nadir. The outer concentric circle that represents the zenith should have a radius larger that the inner concentric circle and should also be centered about the center point.Type: GrantFiled: May 15, 2007Date of Patent: March 15, 2011Assignee: George Mason Intellectual Properties, Inc.Inventor: Kenneth J. Hintz
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Patent number: 7904962Abstract: Disclosed is a system for modeling, analyzing, and responding to network attacks. Machines are mapped to components, components are mapped to vulnerabilities, and vulnerabilities are mapped to exploits. Each of the exploits includes at least one precondition mapped to at least one postcondition. An attack graph which defines inter-exploit distances is generated using at least one of the exploits. The attack graph is aggregated. At least one hardening option is determined using the aggregated attack graph. Hardening options include applying at least one corrective measure to at least one initial condition, where the initial condition is the initial state of a precondition.Type: GrantFiled: March 10, 2006Date of Patent: March 8, 2011Assignee: George Mason Intellectual Properties, Inc.Inventors: Sushil Jajodia, Steven E. Noel, Pramod Kalapa, Brian C. O'Berry, Michael A. Jacobs, Eric B. Robertson, Robert G. Weierbach
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Publication number: 20110054303Abstract: There is provided a device for generating a frame of reference and tracking the position and orientation of a tool in computer-assisted image guided surgery or therapy system. A first curvature sensor including fiducial markers is provided for positioning on a patient prior to volumetric imaging, and sensing the patient's body position during surgery. A second curvature sensor is coupled to the first curvature sensor at one end and to a tool at the other end to inform the computer-assisted image guided surgery or therapy system of the position and orientation of the tool with respect to the patient's body. A system is provided that incorporates curvature sensors, a garment for sensing the body position of a person, and a method for registering a patient's body to a volumetric image data set in preparation for computer-assisted surgery or other therapeutic interventions. This system can be adapted for remote applications as well.Type: ApplicationFiled: May 18, 2010Publication date: March 3, 2011Applicant: GEORGE MASON INTELLECTUAL PROPERTIES, INC.Inventors: Earl Frederick Barrick, Judy Barrick, Kenneth J. Hintz
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Publication number: 20110046039Abstract: The invention provides methods and materials for identifying agents for preventing and/or treating anthrax and similar diseases. Embodiments provide strains and model systems for studying non-lethal and lethal exposure to anthrax and similar disease vectors. Embodiments provide materials and methods for using the strains and model systems for differential profiling, such as proteomic profiling, such as differentiation phosphorylation profiling, to target identification and therapeutics discovery and development. Embodiments provide pharmaceutically acceptable compositions, and methods for using them to prevent and/or treat anthrax and similar diseases comprising an agent that decreases the activity of caspase ¼, such as YVAD, and/or an agent that increases the phosphorylation of AKT, such as IB-MECA or Cl-IB-MECA, together with, in particular embodiments, an antibiotic, such as ciprofloxacin. Kits comprising the same are provided as well, among other things.Type: ApplicationFiled: March 6, 2008Publication date: February 24, 2011Applicant: George Mason Intellectual Properties Inc.Inventors: Serguei G. Popov, Taissia Popov, Virginia Espina, Charles Bailey, Lance A. Liotta, Emanuel Petricoin
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Patent number: 7890266Abstract: The present invention introduces an innovative data mining technique to identify precursory signals associated with earthquakes. It involves a multistrategy approach that employs one-dimensional wavelet transformations to identify singularities in data, and analyzes the continuity of wavelet maxima in time and space to determine the singularities that could be precursory signals. Surface Latent Heat Flux (SLHF) data may be used. A single prominent SLHF anomaly may be found to be associated some days prior to a main earthquake event.Type: GrantFiled: October 6, 2009Date of Patent: February 15, 2011Assignee: George Mason Intellectual Properties, Inc.Inventors: Guido Cervone, Menas Kafatos, Domenico Napoletani, Ramesh P. Singh
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Patent number: 7871824Abstract: A flow chamber having a vacuum chamber and a specimen chamber. The specimen chamber may have an opening through which a fluid may be introduced and an opening through which the fluid may exit. The vacuum chamber may have an opening through which contents of the vacuum chamber may be evacuated. A portion of the flow chamber may be flexible, and a vacuum may be used to hold the components of the flow chamber together.Type: GrantFiled: April 5, 2006Date of Patent: January 18, 2011Assignee: George Mason Intellectual Properties, Inc.Inventor: Victor Morozov
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Patent number: 7850915Abstract: The invention contemplates apparatuses for recognition of proteins and other biological molecules by imaging morphology, size and distribution of crystalline and amorphous dry residues in droplets (further referred to as “crystallization patterns”) containing predetermined amount of certain crystal-forming organic compounds (reporters) to which protein to be analyzed is added. Changes in the crystallization patterns of a number of amino-acids can be used as a “signature” of a protein added. Also, changes in the crystallization patterns, as well as the character of such changes, can be used as recognition elements in analysis of protein molecules.Type: GrantFiled: March 3, 2008Date of Patent: December 14, 2010Assignee: George Mason Intellectual Properties, Inc.Inventors: Victor Morozov, Charles L. Bailey, Nikolai N. Vsevolodov, Adam Elliott
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Patent number: 7848904Abstract: A multidimensional sensor data analyzer that includes: discretizing values in multidimensional sensor data at index locations in value surfaces that reside in a multidimensional value space; deriving surface components resulting from the intersection of a geometric beam shape function that describing the sensor beam with the value surfaces; determining minimum-maximum index location limits for the surface components; determining surface component index points by identifying the index locations that are located within the minimum-maximum index location limits for the surface components; and generating a beam value by performing a beam function using the values at the surface component index points.Type: GrantFiled: March 1, 2010Date of Patent: December 7, 2010Assignee: George Mason Intellectual Properties, Inc.Inventor: Kenneth J. Hintz
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Publication number: 20100298157Abstract: A subject's likelihood of responding to bariatric surgery can be assessed by measuring the phosphorylation state of certain proteins found in white adipose tissue (WAT). In particular, measuring the phosphorylation state of particular proteins can predict a patient's likelihood of resolving diabetes mellitus following bariatric surgery. In addition, evaluating the phosphorylation state of certain proteins forecasts a patient's capacity to reduce excess body weight and/or waist size following bariatric surgery. Such tests are valuable tools for managing the diseases of diabetes and obesity and determining who would most likely benefit from bariatric surgical procedures such as gastic bypass surgery.Type: ApplicationFiled: May 19, 2008Publication date: November 25, 2010Applicants: GEORGE MASON INTELLECTUAL PROPERTIES, INC., INOVA HEALTH CARE SERVICESInventors: Emanuel Petricoin, III, Valerie Calvert, Zobair Younossi, Lance Liotta
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Patent number: 7840505Abstract: A classification system that includes a first input module, a marker module, unclassified Lagrange multiplier calculation module, and a classification module. The unclassified vector describes a physical condition. The marker module assigns a marker to the unclassified vector. The marker should place the unclassified vector into one of two classes. The unclassified Lagrange multiplier calculation module calculates a classifying Lagrange multiplier for the unclassified vector using the marker and a classification rule. The classification rule may be generated using a training system for classifying the physical condition. The classification module is configured to determine that the marker places the unclassified vector in the proper class if the classifying Lagrange multiplier is small.Type: GrantFiled: November 2, 2007Date of Patent: November 23, 2010Assignee: George Mason Intellectual Properties, Inc.Inventors: Roman A. Polyak, Igor Griva, Shen-Shyang Ho
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Patent number: 7830923Abstract: An interval centroid-based watermark encoder encodes a watermark into a packet flow. Intervals are defined for the packet flow. Some of the intervals are selected as group A intervals while other intervals are selected as group B intervals. Group A and group B intervals are paired and assigned to watermark bits. A first or second value may be encoded by increasing the relative packet time between packets in either the group A (for the first bit value) or group B (for the second bit value) interval(s) of the interval pair(s) assigned to the watermark bits that are to represent the first or second bit value and the beginning of the same group interval(s). The relative packet times may be measured by a decoder and used to calculate a centroid difference for each interval pair. The centroid differences may be used to reconstruct the watermark.Type: GrantFiled: April 12, 2010Date of Patent: November 9, 2010Assignee: George Mason Intellectual Properties, Inc.Inventors: Xinyuan Wang, Shiping Chen
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Patent number: 7824871Abstract: Non-invasive methods for detecting non-alcoholic fatty liver disease (NAFLD) and identifying the presence or absence of non-alcoholic steatohepatitis (NASH) in a subject utilize one or more biomarkers. The methods can differentiate between subjects with NASH and those with simple steatosis. Kits containing one or more agents for measuring the level of the biomarkers can be utilized to perform the described methods.Type: GrantFiled: June 13, 2008Date of Patent: November 2, 2010Assignees: George Mason Intellectual Properties, INOVA Health SystemInventors: Zobair M. Younossi, Mohammed H. Jarrar, Vikas Chandhoke, Ancha V. Baranova
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Patent number: 7824927Abstract: Analytes using an active assay may be detected by introducing an analyte solution containing a plurality of analytes to a lacquered membrane. The lacquered membrane may be a membrane having at least one surface treated with a layer of polymers. The lacquered membrane may be semi-permeable to nonanalytes. The layer of polymers may include cross-linked polymers. A plurality of probe molecules may be arrayed and immobilized on the lacquered membrane. An external force may be applied to the analyte solution to move the analytes towards the lacquered membrane. Movement may cause some or all of the analytes to bind to the lacquered membrane. In cases where probe molecules are presented, some or all of the analytes may bind to probe molecules. The direction of the external force may be reversed to remove unbound or weakly bound analytes. Bound analytes may be detected using known detection types.Type: GrantFiled: April 5, 2006Date of Patent: November 2, 2010Assignee: George Mason Intellectual Properties, Inc.Inventors: Victor Morozov, Charles L. Bailey, Melissa R. Evanskey
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Patent number: 7822073Abstract: A packet flow side channel encoder and decoder embeds and extracts a side channel communication in an overt communication data stream transmitted over a network. The encoder selects more than one group of related packets being transmitted on the network, relates a packet of one group to a packet of another group to form a pair of packets; and delays the timing of at least one packet from each pair of packets The decoder determines inter-packet delays that are the difference in timing between two packets in a pair of packets; determines at least one inter-packet delay difference between two or more determined inter-packet delays; and extracts a bit using the at least one interpacket delay difference.Type: GrantFiled: November 3, 2006Date of Patent: October 26, 2010Assignee: George Mason Intellectual Properties, Inc.Inventors: Xinyuan Wang, Shiping Chen, Sushil Jajodia
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Patent number: 7799143Abstract: A radioactive material sequestration system may include a radionuclide containment composition dispenser and a sorption based media container. The radionuclide containment composition dispenser may be configured for holding a radionuclide containment composition and be capable of dispensing the radionuclide containment composition to remove radionuclides from a radioactive material. The radionuclide containment composition is a mixture of a clay mineral and water. The sorption based media container may be configured for holding a sorption based media; receiving dispensed radionuclide containment composition; and sequestering the radionuclides. The radioactive material sequestration system may also include a probe.Type: GrantFiled: November 30, 2009Date of Patent: September 21, 2010Assignee: George Mason Intellectual Properties, Inc.Inventors: Stephen Elmore, Mark Krekeler, Cynthia Tselepis
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Patent number: 7800616Abstract: Using stochastic directed graphs, a social network stochastic directed graph model allows for policy analysis and action. An activity generator may be used for creating agents that represent a population stratum. Agents may be proportionally selected to the size of the population stratum and representative activities that are associated with said population stratum. Agents have one or more conditional probabilities attached to the activities, which indicate the likelihood of interaction between agents and one or more agents or actors. Outcomes for the interactions may be accumulated. Based on these outcomes, which include benign and acute, a multinomial probability distribution may be estimated.Type: GrantFiled: February 27, 2007Date of Patent: September 21, 2010Assignee: George Mason Intellectual Properties, Inc.Inventors: Yasmin H. Said, Edward J. Wegman
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Patent number: 7776405Abstract: The claimed invention describes methods and apparatuses for manufacturing nano-aerosols and nano-structured materials based on the neutralization of charged electrosprayed products with oppositely charged electrosprayed products. Electrosprayed products include molecular ions, nano-clusters and nano-fibers. Nano-aerosols can be generated when neutralization occurs in the gas phase. Neutralization of electrospan nano-fibers with molecular ions and charged nano-clusters may result in the formation of fibrous aerosols or free nano-mats. Nano-mats can also be produced on a suitable substrate, forming efficient nano-filters.Type: GrantFiled: November 17, 2006Date of Patent: August 17, 2010Assignee: George Mason Intellectual Properties, Inc.Inventors: Charles L. Bailey, Victor Morozov, Nikolai N. Vsevolodov
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Patent number: 7747312Abstract: There is provided a device for generating a frame of reference and tracking the position and orientation of a tool in computer-assisted image guided surgery or therapy system. A first curvature sensor including fiducial markers is provided for positioning on a patient prior to volumetric imaging, and sensing the patient's body position during surgery. A second curvature sensor is coupled to the first curvature sensor at one end and to a tool at the other end to inform the computer-assisted image guided surgery or therapy system of the position and orientation of the tool with respect to the patient's body. A system is provided that incorporates curvature sensors, a garment for sensing the body position of a person, and a method for registering a patient's body to a volumetric image data set in preparation for computer-assisted surgery or other therapeutic interventions. This system can be adapted for remote applications as well.Type: GrantFiled: January 3, 2001Date of Patent: June 29, 2010Assignee: George Mason Intellectual Properties, Inc.Inventors: Earl Frederick Barrick, Kenneth J. Hintz
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Patent number: 7730037Abstract: Disclosed is a fragile watermarking scheme for detecting and localizing malicious alterations made to a database relation with categorical attributes without introducing distortions to cover data. A watermark for a tuple group may be inserted by selectively switching the position of tuples in tuple pairs using a tuple hash associated with each tuple in the tuple pair; and a corresponding bit in a watermark derived from the tuple group using a embedding key, a primary key and hash functions.Type: GrantFiled: October 17, 2005Date of Patent: June 1, 2010Assignee: George Mason Intellectual Properties, Inc.Inventors: Sushil Jajodia, Huiping Guo, Yingjiu Li
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Patent number: 7725529Abstract: Disclosed is a geographic information system which comprises a multithreading client and a multithreading server cluster. The multithreading client includes at least one user interface, at least one client coordinator, map data, at least one map manager, at least one client-side spatial analyzer, at least one cache manager, at least one data requester, and at least one information communicator. The multithreading server cluster includes: at least one servlet, at least one image accessor, at least one map configuration mechanism; at least one data storage access mechanism, at least one data source manager, and at least one server-side spatial manager.Type: GrantFiled: November 17, 2004Date of Patent: May 25, 2010Assignee: George Mason Intellectual Properties, Inc.Inventors: Chaowei Yang, Menas Kafatos, David W. Wong, Henry D. Wolf, Ruixin Yang