Patents Assigned to Georgetown University
  • System and method for detecting, collecting, analyzing, and communicating event-related information
    Patent number: 9489495
    Abstract: A system and method involves detecting operational social disruptive events on a global scale, assigning disease event staging and warnings to express data in more simplistic terms, modeling data in conjunction with linguistics analysis to establish responsive actions, generating visualization and modeling capabilities for communicating information, and modeling disease propagation for containment and forecasting purposes.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: November 8, 2016
    Assignee: GEORGETOWN UNIVERSITY
    Inventors: Peter Chao-Yuan Li, Jeffrey R. Collmann, Jane W. Blake, Jae in Yoon
  • Preparation of antibody or an antibody fragment targeted immunoliposomes for systemic administration of therapeutic or diagnostic agents and uses thereof
    Patent number: 9480750
    Abstract: A method of preparing an antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex comprises the steps of (a) preparing an antibody or antibody fragment; (b) mixing said antibody or antibody fragment with a cationic liposome to form a cationic immunoliposome or with a cationic polymer to form a polyplex; and (c) mixing said cationic immunoliposome or said polyplex with a therapeutic or diagnostic agent to form said antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: November 1, 2016
    Assignee: Georgetown University
    Inventors: Esther H. Chang, Kathleen F. Pirollo
  • System and method for deterring malicious network attacks
    Patent number: 9483640
    Abstract: A system and method for deterring malicious network attacks. The system and method is configured to execute instructions on at least one of the processors to generate a plurality of random blocks of data; generate a first XOR result by using the XOR function with the plurality of random blocks of data as the XOR function inputs; generate a tail value by using the XOR function with the first XOR result and a random encryption key as the XOR function inputs; encrypt a designated file using the random encryption key; write the plurality of random blocks and tail value to at least one storage medium; and write the encrypted designated file to at least one storage medium.
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: November 1, 2016
    Assignee: Georgetown University
    Inventor: Thomas Clay Shields
  • Treating neural disease with tyrosine kinase inhibitors
    Patent number: 9474753
    Abstract: Provided herein are methods of treating or preventing a neurodegenerative disease, a myodegenerative disease or a prion disease in a subject comprising administering a tyrosine kinase inhibitor.
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: October 25, 2016
    Assignee: GEORGETOWN UNIVERSITY
    Inventor: Charbel Moussa
  • ELECTRONIC DEVICES WITH ORGANIC NANOPARTICLES
    Publication number: 20160301035
    Abstract: An organic field effect transistor includes a semiconductor substrate having an insulating layer and a source electrode and a drain electrode located on the insulating layer, where the source electrode and drain electrode are spaced apart and define a channel region. The organic field effect transistor also includes an organic semiconductor located in the channel region.
    Type: Application
    Filed: November 25, 2014
    Publication date: October 13, 2016
    Applicant: Georgetown University
    Inventors: Edward Van Keuren, George Burton
  • METHODS AND COMPOSITIONS FOR TREATING CANCER
    Publication number: 20160263086
    Abstract: Methods and compositions provided herein relate to the treatment of cancer. In some embodiments, the compositions have utility in the treatment of cancers including glioblastoma multiforme and lung cancer.
    Type: Application
    Filed: October 20, 2014
    Publication date: September 15, 2016
    Applicant: GEORGETOWN UNIVERSITY
    Inventors: Jeffrey A. Toretsky, Aykut Uren
  • Reversible room-temperature ionic liquids
    Patent number: 9433895
    Abstract: One aspect of the present invention relates to salts that are room-temperature ionic liquids (RTILs), methods of making them, and methods of using them in connection with temporary or permanent gas sequestration. Another aspect of the present invention relates to a class of solvents which can be transformed into RTILs by exposure to a gas, and methods of using them in connection with temporary or permanent gas sequestration.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: September 6, 2016
    Assignee: Georgetown University
    Inventors: Tao Yu, Richard G. Weiss, Taisuke Yamada, Mathew George
  • Methods of treating bacterial infections with 1,2-benzisothiazolinone and isoindolinone derivatives
    Patent number: 9428472
    Abstract: Methods of treating, preventing and ameliorating bacterial infections with 1,2-benzisothiazolinone and isoindolinone derivatives are disclosed. Pharmaceutical compositions containing 1,2-benzisothiazolinone and isoindolinone derivatives are useful for treating bacterial infections caused by drug resistant strains of bacteria, including but not limited to methicillin and vancomycin bacterial organisms.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: August 30, 2016
    Assignee: GEORGETOWN UNIVERSITY
    Inventors: Deepu Alex, Richard Calderone, Stephen Peters
  • Method and system for generating a photo-response from MoS2 schottky junctions
    Patent number: 9431573
    Abstract: Devices incorporating a single to a few-layer MoS2 channels in combination with optimized substrate, dielectric, contact and electrode materials and configurations thereof, exhibit light emission, photoelectric effect, and superconductivity, respectively.
    Type: Grant
    Filed: June 4, 2014
    Date of Patent: August 30, 2016
    Assignee: Georgetown University
    Inventors: Makarand Paranjape, Paola Barbara, Amy Liu, Marcio Fontana
  • Catalytic C—H bond activation
    Patent number: 9416080
    Abstract: Disclosed is a method for the transition metal-mediated oxidation of C—H bonds to form C—O or C—S bonds. The methods are useful for the formation of ethers (R—OR?) from alcohols, R?OH, and sp3-hybridized C—H bonds in substrates, R—H. Aryl or heteroaryl acetates may also be used for C—H to C—OAr bond formation. The methods are also useful in the preparation of C—S bonds from acetyl-protected thiols, MeC(O)SR, and disulfides, RSSR. Advantageously, the methods minimize reaction steps, the handling of oxidized intermediates, and environmental impact.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: August 16, 2016
    Assignee: Georgetown University
    Inventors: Timothy H. Warren, Nicholas G. Sapiezynski
  • Fluorescent CDK inhibitors for treatment of cancer
    Patent number: 9408848
    Abstract: Disclosed are molecules and their synthesis. The fluorescent moiety also facilitates screening, tracking, and pharmacodynamic studies of the drug in a biological system both in vitro and in vivo.
    Type: Grant
    Filed: August 17, 2009
    Date of Patent: August 9, 2016
    Assignee: Georgetown University
    Inventors: Venkata Mahidhar Yenugonda, Milton L. Brown
  • PtCu and PtNi Electrocatalysts Doped with Iodine
    Publication number: 20160226073
    Abstract: Disclosed are metal alloy materials comprising iodine adsorbed onto the catalyst surface exhibiting surprisingly improved performance and durability in comparison with known electrocatalysts. Methods of preparation of the catalysts and methods of use thereof are also described.
    Type: Application
    Filed: August 19, 2014
    Publication date: August 4, 2016
    Applicant: Georgetown University
    Inventors: YuYe J. Tong, Honghui Wang
  • Competitive inhibitor of GP120
    Patent number: 9399663
    Abstract: Peptides and peptide analogs that competitively inhibit HIV protein gp120 and methods for making and using the same.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: July 26, 2016
    Assignee: Georgetown University
    Inventors: Italo Mocchetti, Valeriya Avdoshina
  • ENHANCING THE LEGIBILITY OF IMAGES USING MONOCHROMATIC LIGHT SOURCES
    Publication number: 20160212302
    Abstract: A system and method are described for enhancing readability of document images by operating on each document individually. Monochromatic light sources operating at different wavelengths of light can be used to obtain greyscale images. The greyscale images can then be used in any desired image enhancement algorithm. In one example algorithm, an automated method removes image background noise and improves sharpness of the scripts and characters using edge detection and local color contrast computation.
    Type: Application
    Filed: January 19, 2016
    Publication date: July 21, 2016
    Applicant: Georgetown University
    Inventors: Ophir Frieder, Gideon Frieder, Jon Parker
  • Increasing parkin activity by administering a deubiquitinating enzyme inhibitor
    Patent number: 9393244
    Abstract: Provided herein are methods of promoting parkin activity in a subject, comprising: selecting a subject with a disorder associated with decreased Parkin activity; and administering to the subject an effective amount of a composition that increases parkin activity, wherein the composition is an inhibitor of a deubiquitinating enzyme.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: July 19, 2016
    Assignee: Georgetown University
    Inventor: Charbel Moussa
  • MIRNA in Gulf War Illness
    Publication number: 20160194716
    Abstract: Provided herein is a method of determining a level of one or more miRNAs in a subject that has or is at risk of developing Gulf War Illness (GWI). The method includes obtaining a biological sample from the subject and determining a level of one or more miRNA molecules in the biological sample. Also provided are compositions and kits for carrying out the provided methods.
    Type: Application
    Filed: December 30, 2015
    Publication date: July 7, 2016
    Applicant: GEORGETOWN UNIVERSITY
    Inventors: James N. Baraniuk, Narayan Shivapurkar, Rakib Rayhan
  • Systems and Process For Forming Carbon Nanotube Sensors
    Publication number: 20160181539
    Abstract: A system for forming a functionalized sensor for sensing a molecule of interest includes at least one single or multi-wall carbon nanotube having a first and a second electrode in contact therewith on a substrate; a third electrode including a decorating material on the substrate a predetermined distance from the at least one single or multi-wall carbon nanotube having a first and a second electrode in contact therewith, wherein the decorating material has a bonding affinity for bioreceptors that react with the molecule of interest; and wherein applying a voltage to the third electrode causes the decorating material to form nanoparticles of the decorating material on the at least one single or multi-wall carbon nanotube.
    Type: Application
    Filed: March 2, 2016
    Publication date: June 23, 2016
    Applicant: Georgetown University
    Inventors: Makarand PARANJAPE, Jianyun ZHOU
  • SYSTEM AND METHOD OF APPLYING STATE OF BEING TO HEALTH CARE DELIVERY
    Publication number: 20160180043
    Abstract: A system for assisting a subject to select a proper form of treatment. The system comprises: a monitoring section that remotely monitors a health status of the subject; an inference section that infers medical information about the subject based on information subject posted on social networks; a subject database that stores subject's information; and a symptom engine that stores symptoms of medical situations. The inference section applies the health status and the medical information against symptoms stored in the symptom engine to determine a proper form of treatment.
    Type: Application
    Filed: March 2, 2016
    Publication date: June 23, 2016
    Applicant: Georgetown University
    Inventors: Howard Federoff, Ophir Frieder, Eric Burger
  • SYSTEM AND METHOD FOR DETECTING, COLLECTING, ANALYZING, AND COMMUNICATING EVENT-RELATED INFORMATION
    Publication number: 20160170814
    Abstract: A system and method involves detecting operational social disruptive events on a global scale, modeling data in conjunction with linguistics analysis to establish responsive actions, and generating visualization and executing models for communicating information.
    Type: Application
    Filed: March 18, 2014
    Publication date: June 16, 2016
    Applicant: Georgetown University
    Inventors: Peter C. LI, Manabu TORII, David M. HARTLEY, Noele P. NELSON
  • System and method for enhancing the legibility of degraded images
    Patent number: 9361676
    Abstract: Disclosed are embodiments for a system, method, and computer program product for performing an process on an original image, the process being implemented by a computer system performs a comprising the at least one computer: performing an process on an image that renders the processed image legible than then the original image, wherein the analysis segregates dark pixels of the image from light pixels of the image. The method can comprise: first converting the image into a grayscale image. The method comprises processing a pixel area for each pixel of the image is a dark pixel or a light pixel and determining if a pixel is proximate to an edge.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: June 7, 2016
    Assignee: Georgetown University
    Inventors: Jon Parker, Gideon Frieder, Ophir Frieder