Abstract: An imaging device having an in vivo CMOS image sensor, at least one illumination source and a controller. The controller controls the illumination source to illuminate for a first period and to be shut off for a subsequent period.

Abstract: An imager and a method for real-time, non-destructive monitoring of light incident on imager pixels during their exposure to light. Real-time or present pixel signals, which are indicative of present illumination on the pixels, are compared to a reference signal during the exposure. Adjustments, if necessary, are made to programmable parameters such as gain and/or exposure time to automatically control the imager's exposure to the light. In a preferred exemplary embodiment, only a selected number of pixels are monitored for exposure control as opposed to monitoring the entire pixel array.

Abstract: A system and method may determine the orientation of an in-vivo imaging device relative to the earth's gravitation field. Some embodiments may enable indication of specific locations where other methods provide non-satisfactory imaging coverage. The system may include an in-vivo imaging system with a container or shell containing an orientation object. The container may be placed in at least one optical dome or optical field of an in-vivo imaging device, such as an autonomous capsule. The location of the orientation object's image on the in-vivo imaging device imager, as well as size of the image, may be determined as functions of the location of the orientation object inside the container, for each image acquired.

Abstract: A system and method for determining the path length through a body lumen, for example to a specified location, is described. A location detection system may identify the location in space of an in-vivo device over time. A path-length detection unit may use data from the location detection system to determine a path traveled by an in-vivo device. A site of interest along that path may be identified. The distance of the site of interest from at least one end point of a body lumen may be determined.

Abstract: A device and method is described for enabling an examining device to pass through an abnormally configured body lumen. The device may pass through a body lumen while maintaining an initial dimension. Upon encounter with an abnormally configured body lumen, the device may be depleted and take on a final dimension after a predetermined time period, regardless of its current orientation with respect to the body lumen, so that the device may pass through and vacate the abnormally configured body lumen shortly after the predetermined time period may have elapsed.

Abstract: A system and method for detecting in-vivo content, may include an in-vivo imaging device for capturing a stream of image frames in a GI tract, a content detector for detecting and/or identifying one or more image frames from the stream of image streams that may show content, and a graphical user interface (GUI) to display image frames detected.

Abstract: A system and method for detecting in-vivo content, may include an in-vivo imaging device for capturing a stream of image frames in a GI tract, a content detector for detecting and/or identifying one or more image frames from the stream of image streams that may show content, and a graphical user interface (GUI) to display image frames detected.

Abstract: A device and system enables obtaining data such as in vivo images from within body lumens or cavities, such as images of the gastrointestinal (GI) tract. A device may include an imaging system and a radio frequency (RF) transmitter for transmitting signals from an imaging device to a receiving system. The signal strength of the transmitter may be varied or changed to account for, for example, the amount of signal attenuation resulting from body tissues.

Abstract: A medical wireless imaging device comprises an image sensor, a transmitter, a receiving device, and a plurality of light sources. The transmitter transmits data through a wireless communication link to a processing device. The receiving device wirelessly receives control data from a control unit. Each light source is configured to be individually controlled according to the control data. A reference image is stored for each light source. Intensities of each light source are calculated based on a reference image and on an input image.

Abstract: An in-vivo imaging device including a ballast that may for example orient such device in a known orientation relative to the gravitational force on such ballast. Such imaging device may, for example, assume a known orientation when it is free to move, and may capture images from such known orientation. The device may include one or more imagers, which may be oriented at different angles or points of view (e.g., forward and transverse). A method of use may include moving a patient so that the device inside the patient images different fields of view.

Abstract: A device, system and method for calculating a size of an object using images acquired by a typically moving imager, for example in the gastrointestinal (GI) tract. A distance traveled by the moving imager during image capture may be determined, and spatial coordinates of image pixels may be calculated using the distance. The size of the object may be determined, for example, from the spatial coordinates. The moving imager may be in a swallowable capsule, or, for example, an endoscope.

Abstract: An imaging device having an in vivo CMOS image sensor, at least one illumination source and a controller. The controller controls the illumination source to illuminate for a first period and to be shut off for a subsequent period.

Abstract: A system and method may display an image stream, where an original image stream may be divided into two or more subset images streams, each subset image stream being displayed simultaneously or substantially simultaneously. The images may be collected from an ingestible capsule traversing the GI tract.

Abstract: Methods and systems for producing a 3D image representation of an in vivo object that include illuminating the object with at least two separate illumination sources included in a wireless imaging device, the first of the at least two illumination sources for illuminating said object from a first side of the object and the second of the at least two illumination sources for illuminating said object from a second side of the object; obtaining at least a first image and a second image of the object, whereby the first image is obtained using a first illumination source, and the second image is obtained using the second illumination source; comparing between photometry measurements of reflected light intensity in the at least first and second images; and constructing a 3D image representation of the object from the at least first and second images, based on said comparison.

Abstract: An in-vivo device, system, and method are described where an in-vivo device may transmit an image stream to an external receiving device. Reducing the size of the image data necessary for transmission may conserve energy consumed by the in-vivo device during transmission. An image data comparator unit incorporated within the in-vivo device may compare a captured image to a previously transmitted image and transmit, for example, only captured images that are substantially dissimilar to a previously captured image.

Abstract: A system and method may allow displaying a plurality of image streams, where the image streams may be divided, for example into a number of selected subset couplet images which follow predetermined criteria. According to some embodiments, each couplet may be displayed simultaneously or substantially simultaneously. A workstation may accept the images acquired by, for example a capsule and may display the images on a monitor as a moving image.

Abstract: An in vivo device for sensing a lumen such as the GI tract, such as an in vivo imaging device or other sensing device, may include a substantially spherical housing and an oblong appendage attached to the housing. The appendage may be detached in vivo, for example in the stomach. The in vivo device may then roll and glide along a stomach wall to provide, for example, a smooth sampled image stream.

Abstract: A system and method may display an image stream, where an original image stream may be divided into two or more subset images streams, each subset image stream being displayed simultaneously or substantially simultaneously. Post processing may be used to fuse images shown simultaneously or substantially simultaneously. The images may be collected from an ingestible capsule traversing the GI tract.

Abstract: Provided are a system and method for in vivo and in situ detection of body lumen conditions. The system comprises at least one interaction chamber for containing an endo-luminal sample, the interaction chamber comprising at least one indicator; at least one light source for illuminating the interaction chamber; and at least one optical detector for detecting in vivo optical changes occurring in the interaction chamber. The reaction between the indicator and sample may result in an optical change, which is detected and possibly imaged by the optical detector.

Abstract: An in vivo device and a method for collecting and measuring oximetry data in a body lumen, such as using a swallowable capsule. The in vivo device may include instruments for collecting oximetry data, for example an illuminator and an oximetry data detector.