Abstract: In-vivo devices, systems and methods for the detection of blood within in-vivo bodily fluids. The methods include irradiating in-vivo fluids passing through a gap in a housing of an in-vivo device introduced to the GI tract of a subject with a plurality of illumination sources positioned on a first side of a gap; detecting with at least one light detector positioned on the opposite side of the gap and facing the illumination sources, light irradiated by the illumination sources; transmitting a plurality of values representing the light detected over time; converting these values to blood concentration values over time, and comparing the blood concentration values to a predetermined threshold value. Based on the comparison, the method includes determining the type of bleeding profile, such that if a plurality of blood concentration values measured consecutively is above the threshold value, the bleeding profile indicates bleeding.

Abstract: An in vivo capsule has a cauterization element that may be deployed by physician while in vivo for cauterizing a lesion, such as bleeding. Energy is transferred from outside of the patient's body to the capsule and specifically to the ablating element, such as via a resonance circuit. Accordingly, it is the object of the present invention to provide a method and apparatus for precisely cauterizing or ablating tissue in-vivo. Embodiments of the invention may provide an in-vivo device having a cauterization or ablation element incorporated therein and a system and method for controlled navigation of the in-vivo cauterization device through a body lumen.

Abstract: Anorectal diagnostic procedures are oftentimes carried out with the patient laying in the left decubitus position, which leads to non-representative response to test maneuvers due to the unnatural position and patient anxiety. Devices spanning, or fastened on, the interglutial cleft of a patient allow for a more natural patient position and eliminate non-representative responses.

Abstract: A system and method for reconstructing locations of sensors in radiopaque images may estimate sensor locations in two groups of good radiographic images and use them to estimate candidate sensor locations in a group of bad radiographic images B1, . . . , Bn in which many sensors are indiscernible. A first iterative process pervading from the first image B1 to the last image Bn may determine a first set of candidate sensor locations, and a second iterative process pervading from the last image Bn to the first image B1 may determine a second set of candidate sensor location for each image. Location of a sensor in each image Bi may be estimated based on the pertinent first and second candidate sensor locations related, or determined for, the particular sensor in the particular image. Sensor locations still missing in the series of images are, then, estimated using the already estimated sensor locations.

Abstract: A method and device may control energy consumption of in an in vivo imaging device by determining or estimating an amount of energy needed to capture images at a frame rate until a complete passage of the device through a predetermined region of the gastrointestinal tract, and alter or limit the frame capture rate accordingly.

Abstract: A device and method for example operating an in vivo imaging device wherein the illumination is operated at a certain rate or range of rates, and images are transmitted from the device.

Abstract: An in-vivo imaging device for capturing one or more narrow band images of the gastrointestinal tract, or other body lumens or cavities of a patient, using one or more narrow band illumination sources and an imager having an array of light sensitive elements.

Abstract: A device for cryotherapy treatment of gastrointestinal lesions includes a cooling member that may be attached to a first tube for pressurizing cryogenic fluid through the tube and into the cooling member through nozzles located at the distal end of the first tube. A second tube may be attached to the cooling member for evacuating the cryogenic fluid from within the cooling member, following the fluid's expansion once it exits the first tube. The cryotherapy device may be attached to an endoscope such that the first tube may be passed through the endoscope's working channel, while the second tube may be passed along the endoscope's circumference. The cryotherapy device may further comprise securing means attached to the first tube, for securing the first tube to the endoscope's working channel, thus preventing free rotation of the cryotherapy device within the endoscope, relative to the rotation of the endoscope.

Abstract: In general, this disclosure describes techniques for placing a capsule for sensing one or more parameters of a patient. In particular, the techniques provide for anchoring of the capsule to a tissue at a specific site and releasing the capsule from the device using a single actuator. As an example, a delivery device may anchor the capsule to the tissue site during a first motion of the actuator and release the capsule from the delivery device during a second motion of the actuator. This allows a user to place the capsule by interacting with only a single actuator, thus making delivery of the capsule easier and more reliable.

Abstract: The invention provides a device for in-vivo imaging, for example, using an in-vivo imaging device including an imager a lens and an illumination source, all positioned behind a single viewing window. The in-vivo imaging device may include an element to block light from reaching a point of reflection on the inner surface of the viewing window, thereby preventing the light from being received by the imager.

Abstract: A device and system for monitoring the status of a battery in an in-vivo imaging device, prior to use of the in-vivo imaging device. The device may include a frame counter for counting the number of frames captured and may include monitoring the voltage of the battery. A warning signal is generated if it is determined that the battery is faulty prior to use. The warning signal can be generated by the device and/or by a receiver which receives data from the in-vivo imaging device and/or a by workstation which receives the data from the receiver.

Abstract: Devices, systems and methods for displaying in-vivo images at variable rate. For example, a system includes a processor to gradually increase a frame display rate of an in-vivo image stream based on a similarity among two or more in-vivo frames of the in-vivo image stream.

Abstract: Embodiments of the invention include a method and system for displaying an in vivo imaging procedure. The method includes receiving real-time image data captured by the capsule, and continuously generating an updated summarized color bar, said color bar comprising color strips and time scale marks. The color bar is calculated based on color values of received image data, and is updated continuously as new image data is received. The displayed time period is periodically updated, for example based on predetermined fixed time intervals, based on varying time intervals, or based on an accumulated amount of received image data. Other methods of determining the periodic updates may be used.

Abstract: An in-vivo device may allocate a sensing window in a work cycle for sensing and processing localization signals to determine the location/orientation of the in-vivo device. The in-vivo device may use a timing unit to schedule transmission of data frames and the sensing of the localization signals relative to a reference time embedded in work cycles. The timing unit may produce a clock signal based on which the in-vivo device may measure time specifics, which define the sensing window, relative to the reference time. A receiver may use data embedded in data frames to restore the clock signal and the reference time, and, from them, and using identical or similar time specifics, generate a synchronization signal for a localization signals source (LSS) to enable the LSS to generate localization signals in synchronization with the sensing windows.

Abstract: A system and method may analyse and display intestinal motility events, based on an image stream captured by an in vivo imaging device. According to some embodiments, the system includes a storage unit to store image frames from the image stream, a processor to select a strip of pixels from a plurality of image frames of the image stream and to align the selected strips adjacently to form a motility events bar, and a visual display unit for displaying the motility events bar to a user.

Abstract: An in-vivo device includes a first communication circuit to communicate with an external communication device by using a first communication protocol while the in- vivo device is in the gastrointestinal system of a subject, a communication condition monitoring (CCM) circuit to monitor communication conditions for the first communication circuit, a second communication circuit to communicate with the external communication device by using a second communication protocol, and a controller configured to receive, from the communication condition monitoring (CCM) circuit, a signal indicative of a communication condition of the communication via the first communication circuit, to compare the communication condition to prerequisite communication condition(s), and to activate the first communication circuit and concurrently deactivate the second communication circuit, or vice versa, based on the comparison result.

Abstract: Embodiments of the invention are related to a system and method of controlling a display of image stream. The system may include a memory to store the image stream; the image stream may comprise a plurality of image frames. The system may further include a processor configured to execute the method. The moving image stream may be displayed to a user in an image stream display area of a screen and a frame rate control interface may be generated on a speed control area of the screen, such that the image stream display area is horizontally adjacent to the speed control area. An indication of a desired frame rate for displaying the image stream of the image frames may be received from the user, in that the frame rate may be selected according to a location of a pointing indicator in the speed control area.

Abstract: An in-vivo imaging device and method for performing spectral analysis include inserting the in-vivo device into a patient's lumen, illuminating the tissue lumen and collecting the light scattered and reflected from the tissue. The device may comprise at least six illumination sources for illuminating the tissue. At least two of the six illumination sources illuminate at a different wavelength in the blue spectral region, at least two illuminate at a different wavelength in the green spectral region, and at least two illuminate at a different wavelength in the red spectral region. The illumination sources are adapted to illuminate in groups of three, wherein each group of three illumination sources comprises one illumination source that illuminates in the blue spectral region, one in the green spectral region, and one in the red spectral region. Each group of three illumination sources illuminates simultaneously.

Abstract: An in-vivo imaging system and method to automatically detect a pathology frame sequence in an image stream captured in vivo. An image stream comprising a plurality of image frames captured in vivo may be received, and a pathology score for at least a portion of the image frames is received. A seed frame which includes at least one pathology candidate may be selected, and the position of the pathology candidate in the seed frame may be determined. A sequence of frames adjacent to the seed frame is defined comprising frames that depict the pathology candidate, and a pathology sequence score is calculated based on the sequence, the pathology sequence score correlating to the probability that the sequence of frames adjacent to the seed frame includes a pathology. If the pathology sequence score is within a range, a display method may be adapted, or the pathology score may be changed based.

Abstract: The present invention provides a system and method for obtaining in vivo images. The system contains an imaging system and a transmitter for transmitting signals from a camera to a receiving system located outside a patient.