Abstract: A system and method for estimating a size of an object in an image is provided. A tissue model may be provided. Points in an image may be selected. A distance or estimated distance of the points from an imaging device may be determined based on the tissue model. A geometrical relation associating the point, distances and an object may be derived. A size parameter of the object may be calculated based on the geometrical relation. Other embodiments are described and claimed.

Abstract: A system, method and virtual tool for size estimation of in-vivo objects includes receiving and displaying a two-dimensional image of in-vivo objects obtained by in-vivo imaging device; receiving indication of a selected area representing a point of interest from the user via a user input device; estimating depth of a plurality of image pixels around the selected area; calculating three-dimensional coordinates representation of the plurality of image points, based on the estimated depths; casting a virtual tool of a known size onto the three-dimensional representation; and projecting the virtual tool onto the two-dimensional image to create a cursor having a two-dimensional shape on the displayed image.

Abstract: The invention provides a device for in-vivo imaging, for example, using an in-vivo imaging device including an imager a lens and an illumination source, all positioned behind a single viewing window. The in-vivo imaging device may include an element to block light from reaching a point of reflection on the inner surface of the viewing window, thereby preventing the light from being received by the imager.

Abstract: The present invention provides a system and method for obtaining in vivo images. The system contains an imaging system and a transmitter for transmitting signals from a camera to a receiving system located outside a patient.

Abstract: A device, system and method for cytology acquisition which may be performed with a swallowable in vivo device, specifically with a swallowable endoscopy capsule. The swallowable capsule may comprise a rotatable drum, a brush attached onto the drum for brushing against a tissue and acquiring cytology, and a porthole through which the brush may be in contact with the tissue.

Abstract: An optimization unit controls electrical currents of a set of electromagnets to generate a wanted maneuvering magnetic field pattern (MMP) for moving an in-vivo device in the GI system. The optimization unit may calculate a magnetic force and a magnetic field to maneuver the in-vivo device from a current location and/or orientation to a new location and/or orientation. The optimization unit may solve a magnetic force optimization problem with respect to the magnetic force in order to determine electrical currents suitable for generating the wanted MMP. The optimization unit may additionally or alternatively solve a minimum electrical power optimization problem with respect to the electrical power to be consumed by the electromagnets in order to recalculate or adjust the electrical currents. The optimization unit may solve one or more of the optimization problems while complying with a set of constraints associated with or derived from each type of optimization objective.

Abstract: A system and method for detection of calorimetric abnormalities within a body lumen includes an image receiver for receiving images from within the body lumen. Also included are a transmitter for transmitting the images to a receiver, and a processor for generating a probability indication of presence of colorimetric abnormalities on comparison of color content of the images and at least one reference value.

Abstract: A system and method for acquiring images containing spatial and spectral information of an object include acquiring defocused images using an optical system based on extended depth of field. The optical system further includes a filter array comprising an array of at least six different sub-filters that are arranged such that any group of four immediately adjacent sub-filters includes at least one red sub-filter, at least one green sub-filter and at least one blue sub-filter. The filter array is located at the aperture stop of the optical system. A coded mask is located at the focal plane of the optical system, and an imager is located beyond the focal plane such that images acquired by the imager are defocused. The images are refocused, and spectral and spatial information is restored by designated software.

Abstract: A system and method for identifying an in-vivo image frame with one or more polyps. Center points of candidate imaged structures may be determined, each center point defining a respective circle. Polyp edge scores may be computed for a plurality of points around each center point, each polyp edge score measuring the coincidence of a respective candidate imaged structure and its respective circle. For each center point, a plurality of edge points of the respective candidate imaged structure may be detected based on the polyp edge score and a candidate imaged structure may be identified based on the detected edge points. For each candidate imaged structure, a candidate polyp may be identified for which extrapolating the detected edge points forms an edge in a shape approximating an ellipse. Image frames with candidate polyps contributing to an above threshold overall image score are determined and marked to include a polyp.

Abstract: A device and method for viewing a body lumen are provided. An assembly of a capsule endoscope and an endoscope is inserted into a body lumen. The capsule endoscope is positioned within the body lumen at a predetermined distance from the endoscope, and images are obtained from opposite sides of a desired location in the body lumen. In vivo procedures may be performed, while images of the procedure are obtained from opposite sides of the procedure location.

Abstract: A system and method for determining location and orientation of an in-vivo device, with respect to an external system in which the device is located include a frame with external magnets attached thereon. An in-vivo device is inserted into the patient's body, which is placed within the system, and the external magnets apply magnetic forces on the in-vivo device. A radio beacon transmitter is attached to the frame for transmitting a radio pulse. The in-vivo device includes an ultrasonic transmitter for transmitting an ultrasonic signal, which is triggered by the radio pulse. At least three transponders are placed on the patient's body, each transponder sending a first acoustic signal triggered by the radio pulse, and each sending a second acoustic signal triggered by the device's ultrasonic signal.

Abstract: A system and method for detecting a transition in a stream of images of a gastrointestinal (GI) tract may include selecting images from an in-vivo image stream; calculating a segment score for each selected image indicating in which segment of the GI tract the image was captured; applying a smoothing function on the scores; detecting a global step in the smoothed segment score signal indicating a substantial change in a parameter calculated based on segment score signal values of the segment score signal values; detecting a local step indicating a substantial change in a parameter calculated based on segment score signal values of a predetermined interval of the of the segment score signal values; combining the local step and the global step; and determining a point of transition in the stream from one anatomical segment to another, the point of transition correlating to the combined step.

Abstract: The invention provides a device for in-vivo imaging, for example, using an in-vivo imaging device including an imager a lens and an illumination source, all positioned behind a single viewing window. The in-vivo imaging device may include an element to block light from reaching a point of reflection on the inner surface of the viewing window, thereby preventing the light from being received by the imager.

Abstract: A device, system, and method for activating and initializing an in vivo imaging device with an RF radiation signal. Functionality of the in vivo imaging device is tested and results may be reported to a user. The in vivo imaging device may include an RF switch to facilitate powering or deactivation of one or more electrical components of the device. The initialization system may include an optical artifact testing unit, a field of illumination testing unit, and a transmission/reception testing unit. The activation system may comprise an in vivo device association unit which may relate a designated device to a single data recorder or to a single controller.

Abstract: A method and system cascade analysis for intestinal contraction detection is provided by extracting from image frames captured in-vivo. The method and system also relate to the detection of turbid liquids in intestinal tracts, to automatic detection of video image frames taken in the gastrointestinal tract including a field of view obstructed by turbid media, and more particularly to extraction of image data obstructed by turbid media.

Abstract: An in-vivo imaging device including a camera may include a frame storage device. Systems and methods which vary the frame capture rate of the camera and/or frame display rate of the display unit of in-vivo camera systems are discussed. The capture rate is varied based on for example, a physical quantity experienced by the camera system, or physical measurements related to the motion of the camera. Alternatively, the frame capture rate is varied based on comparative image processing of a plurality of frames. The frame display rate of the system may be varied based on comparative image processing of a multiplicity of frames. Both the frame capture and the frame display rates of such systems can be varied concurrently.

Abstract: A control circuit for controlling a state of a switching circuit may include a first unit to sense and interpret a wireless signal or physical parameter as an “on” signal to transition the switching circuit to the “on” state, or as an “off” signal to transition the switching circuit to the “off” state, and to transfer a first digital signal or logic value and/or a second digital signal or logic value, which may respectively or combinatorially represent the “on” signal or the “off” signal, to a second unit via a first output and/or a second output of the first unit, respectively. The second unit may force a control input of the switching circuit to a logic value which is a function of the first digital signal or value and/or second digital signal or value and congruent with the state to which the switching circuit is to be transitioned.

Abstract: In-vivo medical devices, systems and methods of operating such devices include a permanent magnetic assembly interacting with external magnetic fields for magnetically maneuvering said device to a desired location along a patient's GI tract, and anchoring said devices to the desired location for a period of time. The in-vivo medical device includes illumination sources, an optical system, and an image sensor for imaging the GI tract and thus assisting in locating the desired location. Some in-vivo medical devices include a concave window, which enables better imaging of small areas along the tissue. Furthermore, in-vivo devices with a concave window enable carrying operating tools without damaging the tissue of the GI tract, since prior to operation, the tools protrude from the concave window but remain behind the ends of the edges of the concave window.

Abstract: A device and method for operating an in vivo imaging device (10A) wherein the illumination produced by the device may be varied in intensity and/or duration, and/or the gain level or other parameters may be varied, according to, for example, the amount of illumination produced by the device which is reflected back to the device. In addition, a method is provided for detecting problematic pixels in an imaging device. This method may define and exclude non-functional pixels, based on for example an initial short exposure that enables a threshold saturation level to be reached only for problematic pixels. Moreover, a method is described for determining when an in vivo device enters the body, for example by calculating the progress of a dark frame, based on the light saturation threshold of the dark frame.

Abstract: A device, system and method may enable the obtaining of in vivo images from within body lumens or cavities, such as images of the gastrointestinal (GI) tract, where the data such as mosaic image data may be transmitted or otherwise sent to a receiving system in a compressed format.