Abstract: A system and method for ulcer detection which may generate a vector of grades including grades indicative of a probability that the image includes an ulcer, for example an ulcer of specific type. For each grade, generating may include finding ulcer candidates within the image, and for each ulcer candidate, building a property vector describing properties of the ulcer candidate and employing a trained classifier to generate the grade from the property vector. The grades may be combined to obtain an indication or score of the probability that the image includes an ulcer.

Abstract: Ulcer detection may include calculating ulcer head scores for image pixels, and calculating ulcer red region scores for pixels, each score correlated to the probability that the pixel color is typical to ulcer heads, ulcer red regions, or a other regions. Ulcer head scores may be compared to an ulcer head threshold level and, based on the results, ulcer head candidates may be obtained. Ulcer red region scores may be compared to a threshold and ulcer red region candidates may be obtained. Ulcer candidates may be formed by creating pairs including an ulcer head candidate and a potential ulcer red region candidate. A grade for ulcer candidates indicating the probability that the ulcer candidate is an ulcer may be used to generate a score for the image, the score indicating the probability that the image includes an ulcer.

Abstract: An in-vivo device may capture images of the GI system and transfer frames to an external system for analysis. As frames are transferred from the in-vivo device to the external system each frame may be scored as belonging to a first GI section or to a second GI section, and the frame scores may be buffered in a score buffer. Based on shifting of a reference function across the buffered frame scores and calculating distances between the buffered frame scores and the shifted reference function, the time at which the in-vivo device transitions from the first section of the GI system to the second section of the GI section may be determined.

Abstract: A system and method for detection of colorimetric abnormalities within a body lumen includes an image receiver for receiving images from within the body lumen. Also included are a transmitter for transmitting the images to a receiver, and a processor for generating a probability indication of presence of colorimetric abnormalities on comparison of color content of the images and at least one reference value.

Abstract: A method and device may control energy consumption of in an in vivo imaging device by determining or estimating an amount of energy needed to capture images at a frame rate until a complete passage of the device through a predetermined region of the gastrointestinal tract, and alter or limit the frame capture rate accordingly.

Abstract: A device, system and method for detecting bile and blood are provided. The device may comprise a housing having a gap through which in-vivo fluids may flow, illumination sources on one side of the gap, a light detector which is facing the illumination sources and is positioned on the opposite side of the gap for detecting light which passes through the in-vivo fluids, and a transmitter to transmit the detected signals generated according to the detected light. The system may further comprise a receiver to receive the detected signals transmitted by the transmitter, and a processor. The method may comprise comparing the detected signals with a predetermined threshold calculated from the transmission spectra of bile and of blood and determining the presence and/or concentration of bile and blood in-vivo.

Abstract: A system and method for detecting an anomaly in a tissue captured or imaged by an imaging system are provided. A uniform region in an image representing a tissue may be defined by identifying a group of pixels associated with a predefined variance from an imaging parameter value. An adaptive size window may be used to define a sub-region in a uniform region. An anomaly may be detected by identifying, in the sub-region, a set of pixels associated with imaging parameter values indicative of an anomaly. Other embodiments are described and claimed.

Abstract: A system and method may identify pathologies such as red pathologies in in-vivo images. Candidate pathology regions may be identified by identifying red regions. Features indicative of the probability of pathology in candidate regions may be identified. An image score for an image may be identified based on one or more identified features, the image score indicative of existence in the image of at least one candidate region with high probability of pathology. Calculating an image score may include calculating a candidate score for at least one identified candidate region based on features, the candidate score indicative of the probability of pathology being imaged in said candidate region, where the image score corresponds to the candidate score of the candidate region with the highest probability of pathology in the image.

Abstract: Device, system and method for in-vivo detection of H. pylori. For example, an in-vivo device includes a housing, a reference electrode disposed on the housing, and a working electrode disposed on the housing in close proximity to the reference electrode. The working electrode is coated by litography or screen printing with salt such that substantially no current passes between the working electrode and the reference electrode. The in-vivo device further includes a measuring device for measuring current, impedance, and/or resistance between the working and the reference electrodes, and a transmitter for transmitting the measurements. Presence of ammonia, which is a byproduct of H. pylori, causes increase in current and thus decrease in impedance or resistance between the reference electrode and the working electrode; thereby measurements of current, impedance, and/or resistance indicate on presence or absence of H. pylori.

Abstract: A system and method for detecting in-vivo content includes an in-vivo imaging device for capturing a stream of image frames in a GI tract, a content detector for detecting and/or identifying one or more image frames from the stream of image streams that may show substantially only content, a display selector to remove detected frames from the image stream, and a monitor to display the remaining image frames as a reduced image stream.

Abstract: Devices and a system for detection of blood within in-vivo fluids are provided. A device comprises a housing that includes a gap. The gap has at least one opening through which in-vivo fluids may enter and/or exit the gap. The device further comprises an illumination source for illuminating the in-vivo fluids in the gap, a light detector for detecting light which passes through the in-vivo fluids in the gap, and flexible fins disposed on the housing in the vicinity of the gap's opening for covering the opening when the fins are folded and for pumping fluids into and out of the opening by repeated closure and opening of the opening by the fins, due to repeated peristaltic waves. This pumping effect may lead to continuous flow of fluids into and out of the opening and thus into and out of the gap of the device.

Abstract: A system and method for editing an image stream captured by an in-vivo imaging device that passes through the GI tract. The image stream including a plurality of image frames. A plurality of image sequences in the image stream may be detected. The plurality of image sequences may capture the same GI tract region. Some of the plurality of image sequences may be excluded from an edited image stream. The edited image stream may be displayed on a monitor.

Abstract: A method and system for automatically detecting villi texture in in-vivo images. In-vivo images may be received from an in vivo imaging capsule, and at least one image may be selected for analysis. Textural details may be extracted, for example using morphological top hat transforms. The image may be divided into segments or patches. The patches may be pruned using a set of threshold conditions, which are calculated based on grayscale or color statistics of the patches. The patches may be classified as containing villi texture or not based for example on rotation-invariant textural features computed in the Fourier domain. A sum, score or rating for the image may be calculated based on the classification of each patch. The final score of the image may be averaged over a number of, for example, consecutive images, and the score may be used for detecting entry into the small bowel and segmenting the image stream to anatomical regions.

Abstract: A system and method may allow editing of an image stream, which may be produced by, for example, an ingestible capsule. A workstation accepts images acquired by the capsule and displays the images on a monitor as a moving image. The editing method may include, for example, selecting images which follow predetermined criteria. A shortened movie may thus be created.

Abstract: A device for in vivo analysis includes: a reaction chamber to store a detecting reagent able to react with a sample collected in vivo; and optionally a labeled-substance chamber to store a labeled substance able to bind to at least a portion of a compound resulting from a reaction of the detecting reagent and the sample. The in-vivo imaging device, typically an autonomous capsule, may have a housing, the housing comprising a window; an illumination source located within the housing to illuminate a body lumen through the window; an imager to receive light reflected from the body lumen through the window; and a transmitter to transmit image data to a receiving system. The window is coated with liposomes containing a marker such that the imager may acquire images which include the marking.

Abstract: A system, method and device for immobilizing an imager in-vivo and/or focusing images on the imager reflected from an in-vivo site to be monitored with for example a moveable or otherwise adjustable focusing mechanism. The imaging sensor may for example be positioned on an acute angle to an in-vivo surface to which the device is immobilized so that the device may for example image an in-vivo area that is opposed to such device. Sensors in addition to or other than an imaging sensor may be used.

Abstract: A method and system for determining intestinal dysfunction condition are provided by classifying and analyzing image frames captured in-vivo. The method and system also relate to the detection of contractile activity in intestinal tracts, to automatic detection of video image frames taken in the gastrointestinal tract including contractile activity, and more particularly to measurement and analysis of contractile activity of the GI tract based on image intensity of in vivo image data.

Abstract: The present invention provides a system and method for obtaining in vivo images. The system contains an imaging system and a transmitter for transmitting signals from a camera to a receiving system located outside a patient.

Abstract: A system and method may allow editing of an image stream, which may be produced by, for example, an ingestible capsule. A workstation accepts images acquired by the capsule and displays the images on a monitor as a moving image. The editing method may include, for example, selecting images which follow or conform to a combination of a plurality of predetermined criteria. A shortened movie may thus be created.

Abstract: A system and method for indicating transferability of a non-dissolvable target in-vivo device through the GI tract are described. The in vivo system includes a dissolvable in-vivo device which has two operational phases; an initial phase in which the device is of initial dimensions and a final phase in which the device is of final dimensions. In the initial phase the device can pass freely through a normally configured body lumen whereas it may not be able to pass freely through an abnormally configured lumen. In the final phase the device can pass freely through a body lumen even if it is abnormally configured.