Patents Assigned to Government of the United States as represented by the Secretary of the Army
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Publication number: 20110171266Abstract: The present invention features immunogenic compositions based on pre-fertilization or post-fertilization antigens expressed in the circulating gametocytes in the peripheral blood of infected persons or on the malaria parastes' stages of develop-ment in the mosquito midgut including extracellular male and female gametes, fertilized zygote and ookinete. The invention also features methods to prevent the transmission of malaria using the immunogenic compositions of the invention.Type: ApplicationFiled: July 22, 2009Publication date: July 14, 2011Applicants: THE JOHNS HOPKINS UNIVERSITY, The Government of the United States, as represented by the Secretary of the ArmyInventors: Nirbhay Kumar, Evelina Angov
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Publication number: 20110111380Abstract: A system for simulating one or more hemorrhages in order to provide a more dynamic and realistic hemorrhage simulation in order to train medical personnel and other critical care givers, such as first responders, medics, and emergency medical technicians (EMTs) on treating hemorrhages. The system includes a reservoir, a flow controller, and at least one conduit connected to at least one simulated wound site wherein the system supplies fluid to the simulated wound site in order to simulate a hemorrhage. The system may further include a plurality of wound sites that have their respective fluid flows controlled by the fluid flow controller. In at least one embodiment, the reservoir and the flow controller are housed within a bag. In at least one embodiment, the system further includes an audio system for providing audio cues to the simulation participants to enhance the realism of the simulation.Type: ApplicationFiled: January 19, 2011Publication date: May 12, 2011Applicant: Government of the United States, as represented by the Secretary of the ArmyInventor: Lynn R. King
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Publication number: 20100059048Abstract: In one embodiment, an apparatus is characterized by an intubation-tube placement device; and an intubation tube secured to the intubation-tube placement device. In another embodiment, an apparatus is characterized by an intubation-tube placement device; and an anti-perforation device coupled to the intubation-tube placement device. In another embodiment, an apparatus is characterized by an intubation-tube placement device; and at least one tactile-accentuator flap coupled to the intubation-tube placement device. In another embodiment, an apparatus is characterized by an intubation-tube placement device; and a handle affixed to the intubation-tube placement device.Type: ApplicationFiled: May 27, 2009Publication date: March 11, 2010Applicant: Government of the United States as represented by the Secretary of the ArmyInventor: Sean O'Mara
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Publication number: 20090310926Abstract: We have shown that a single layer of a 3D Zero Index Material (ZIM) has omnidirectional reflection properties. In the range between the electric plasma frequency and the magnetic plasma frequency, ZIM reflect radiation for all angles of incidence and polarization with reflectivities of ˜99%. In addition, with increasing angles of incidence, the reflecting band does not shift in frequency but actually widens. The operational bandwidth can be 100% or greater by increasing the separation between the electric and magnetic plasma frequencies. We have also shown that in the spectral region that allows the omnidirectional gap, ZIM can be used as the cladding of hollow waveguides with better performance than traditional hollow waveguides.Type: ApplicationFiled: August 24, 2009Publication date: December 17, 2009Applicant: Government of the United States as represented by the Secretary of the ArmyInventors: Giuseppe D'Aguanno, Mark J. Bloemer, Nadia Mattiucci, Michael Scalora
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Publication number: 20090048153Abstract: One embodiment of the present invention provides a composition, comprising, in amounts effective to treat sulfur mustard or half sulfur mustard induced toxicity or skin damage: an agent that inhibits alkylation of —SH and >NH protein groups; an agent that reduces —SS— to SH; a scavenger of reactive oxygen species; a substrate that maintains tissue reduction-oxidation status; an agent that protects against invading inflammatory cells and associated oxidative stress; an antagonist of prostaglandin synthesis; and an agent that induces tissue regeneration. Methods of using the composition are also provided.Type: ApplicationFiled: December 2, 2005Publication date: February 19, 2009Applicants: UNIVERSITY OF MARYLAND, BALTIMORE, The Government of the United States, as represented by the Secretary of the ArmyInventors: Shambhu D. Varma, John Petrali
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Publication number: 20080131461Abstract: The invention relates to novel vaccine regimens in which specific prime/boost regimens are applied using low-neutralized recombinant adenoviral vectors harboring nucleic acids encoding antigens from Plasmodium falciparum and purified recombinant protein vaccines such as RTS,S, in the context of appropriate adjuvants.Type: ApplicationFiled: October 13, 2005Publication date: June 5, 2008Applicants: Crucell Holland B.V., GlaxoSmithKline Biologicals S.A., The Government of the United States as Represented by the Secretary of the ArmyInventors: Maria Grazia Pau, Jaap Goudsmit, Joseph D. Cohen, Patrice Dubois, V.Ann Stewart, Donald Heppner
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Publication number: 20080090103Abstract: Hematin, a hydroxyferriprotoporphyrin, is derivatized with one or more non-proteinaceous amphipathic groups. The derivatized hematin can serve as a mimic of horseradish peroxidase in polymerizing aromatic monomers, such as aromatic compounds. These derivatized hematins can also be used as catalysts in polymerizing aromatic monomers, and can exhibit significantly greater catalytic activity than underivatized hematin in acidic solutions. In one embodiment, polymerization is in the presence of a template, along which aromatic monomers align. An assembled hematin includes alternating layers of hematin and a polyelectrolyte, which are deposited on an electrically charged substrate. Assembled hematin can also be used to polymerize aromatic monomers.Type: ApplicationFiled: September 26, 2007Publication date: April 17, 2008Applicants: University of Massachusetts Lowell, Government of the United States, as Represented by the Secretary of the ArmyInventors: Sukant Tripathy, Susan Tripathy, Lynne Samuelson, Ferdinando Bruno, Sucharita Roy, Ramaswamy Nagarajan, Jayant Kumar, Bon-Cheol Ku, Soo-Hyoung Lee
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Publication number: 20080070900Abstract: A method of treating organophosphorous (OP) poisoning comprising administering to a mammal at risk for OP poisoning an OP poisoning-inhibiting amount of galantamine.Type: ApplicationFiled: September 23, 2005Publication date: March 20, 2008Applicants: University of Maryland, Baltimore, The Government of the United States as represented by The Secretary of the Army, U.S. Army Medical RInventors: Edson Albuquerque, Michael Adler, Edna Pereira
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Publication number: 20080047554Abstract: In one embodiment, a method includes but is not limited to: conditioning an inhalent environment; exposing a first organism to the inhalent environment for a first-organism duration of time; and exposing a second organism to the inhalent environment for a second-organism duration of time. In addition to the foregoing, other method embodiments are described in the claims, drawings, and text forming a part of the present application. In one or more various embodiments, related systems include but are not limited to circuitry and/or programming for effecting the foregoing-referenced method embodiments; the circuitry and/or programming can be virtually any combination of hardware, software, and/or firmware configured to effect the foregoing-referenced method embodiments depending upon the design choices of the system designer.Type: ApplicationFiled: October 30, 2007Publication date: February 28, 2008Applicant: The Government of the United States, As Represented By The Secretary of the ArmyInventors: Chad Roy, Justin Hartings
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Publication number: 20070237478Abstract: We have shown that a single layer of a 3D Zero Index Material (ZIM) has omnidirectional reflection properties. In the range between the electric plasma frequency and the magnetic plasma frequency, ZIM reflect radiation for all angles of incidence and polarization with reflectivities of ˜99%. In addition, with increasing angles of incidence, the reflecting band does not shift in frequency but actually widens. The operational bandwidth can be 100% or greater by increasing the separation between the electric and magnetic plasma frequencies. We have also shown that in the spectral region that allows the omnidirectional gap, ZIM can be used as the cladding of hollow waveguides with better performance than traditional hollow waveguides.Type: ApplicationFiled: April 3, 2006Publication date: October 11, 2007Applicant: Government of the United States as represented by the Secretary of the ArmyInventors: Giuseppe D'Aguanno, Mark Bloemer, Nadia Mattiucci, Michael Scalora
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Publication number: 20040214935Abstract: One group of polymers comprise repeat units of Structural Formula (I) and/or (II): 1Type: ApplicationFiled: January 21, 2004Publication date: October 28, 2004Applicants: University of Massachusetts Lowell, Government of the United States, as represented by the Secretary of the ArmyInventors: Ashok L. Cholli, Vijayendra Kumar, Ashish Dhawan, Jayant Kumar, Virinder Singh Parmar, Lynne Ann Samuelson, Ferdinando F. Bruno
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Publication number: 20040198945Abstract: Hematin, a hydroxyferriprotoporphyrin, is derivatized with one or more non-proteinaceous amphipathic groups. The derivatized hematin can serve as a mimic of horseradish peroxidase in polymerizing aromatic monomers, such as aromatic compounds. These derivatized hematins can also be used as catalysts in polymerizing aromatic monomers, and can exhibit significantly greater catalytic activity than underivatized hematin in acidic solutions. In one embodiment, polymerization is in the presence of a template, along which aromatic monomers align. An assembled hematin includes alternating layers of hematin and a polyelectrolyte, which are deposited on an electrically charged substrate. Assembled hematin can also be used to polymerize aromatic monomers.Type: ApplicationFiled: April 16, 2004Publication date: October 7, 2004Applicants: University of Massachusetts, Government of the United States, as represented by the Secretary of the ArmyInventors: Sukant Tripathy, Susan Tripathy, Lynne A. Samuelson, Ferdinando F. Bruno, Sucharita Roy, Ramaswamy Nagarajan, Jayant Kumar, Bon-Cheol Ku, Soo-Hyoung Lee
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Publication number: 20040047872Abstract: Transcutaneous immunization system delivers antigen to immune cells through topical application, and induces an antigen-specific immune response in an animal or human. The improvement involve a system for marking the successful delivery of the immunization using indicators or using marking systems to allow better application of the patch to a prepared skin surface.Type: ApplicationFiled: September 10, 2003Publication date: March 11, 2004Applicant: The Government of the United States, as represented by the Secretary of the ArmyInventors: Gregory M. Glenn, Carl R. Alving
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Publication number: 20040037391Abstract: An apparatus including but not limited to a charge-coupled device (CCD)-array sensor positioning mechanism, the positioning mechanism structured to position a CCD-array sensor to capture a first target area; and the CCD-array sensor positioning mechanism further structured to position the CCD-array sensor to capture a second target area proximate to the first target area, the first and second target areas spatially related such that a first radiographic image recorded at the first target area may be combined with a second radiographic image recorded at the second target area to form a composite radiographic image substantially analogous to a single radiographic image of an aggregate target area covered by the first and second target areas.Type: ApplicationFiled: April 8, 2003Publication date: February 26, 2004Applicant: Government of the United States, as represented by the Secretary of the ArmyInventor: Steven L. Eikenberg
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Publication number: 20030055354Abstract: In one embodiment, a method includes but is not limited to: conditioning an inhalent environment; exposing a first organism to the inhalent environment for a first-organism duration of time; and exposing a second organism to the inhalent environment for a second-organism duration of time. In one embodiment, a method includes but is not limited to: conditioning an inhalent environment; exposing a first organism to the inhalent environment until a calculated first-organism delivered dosage meets or exceeds a predefined first-organism target dosage; and exposing a second organism to the inhalent environment until a calculated second-organism delivered dosage meets or exceeds a predefined second-organism target dosage. In one embodiment, a method includes but is not limited to: detecting a first organism via a first-organism biochip device implanted in the first organism; and controlling a first-organism dosage in response to the first-organism biochip device.Type: ApplicationFiled: May 29, 2002Publication date: March 20, 2003Applicant: Government of the United States, as represented by the Secretary of the ArmyInventors: Chad J. Roy, Justin M. Hartings
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Publication number: 20020195103Abstract: In one embodiment, an apparatus is characterized by an intubation-tube placement device; and an intubation tube secured to the intubation-tube placement device. In another embodiment, an apparatus is characterized by an intubation-tube placement device; and an anti-perforation device coupled to the intubation-tube placement device. In another embodiment, an apparatus is characterized by an intubation-tube placement device; and at least one tactile-accentuator flap coupled to the intubation-tube placement device. In another embodiment, an apparatus is characterized by an intubation-tube placement device; and a handle affixed to the intubation-tube placement device.Type: ApplicationFiled: March 1, 2002Publication date: December 26, 2002Applicant: Government of the United States, as represented by the Secretary of the ArmyInventor: Sean T. O'Mara
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Publication number: 20020176995Abstract: A method and process for treating wood. The steps include preparing isocyanate-based reactive prepolymer resins for impregnation, impregnating wood with these impregnation resins, curing the impregnated wood at elevated temperatures, preparing isocyanate resin-based coating materials and applying these coating materials on the cured impregnated wood and curing the coatings at room or elevated temperatures.Type: ApplicationFiled: January 17, 2002Publication date: November 28, 2002Applicant: The Government of the United States as represented by the Secretary of the ArmyInventors: Darrel D. Nicholas, Eugene Michael Ivankoe, Moon G. Kim, Charles U. Pittman, Lichang Wang, Ahmed Kabir, Tor P. Schultz, Leonard L. Ingram
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Patent number: 4056290Abstract: The frequency of a laser beam can be changed by directing the laser beam through a crystal that has paraelectric and ferroelectric states, above and below a Curie transition temperature, respectively. The crystal is maintained at a constant temperature slightly above its Curie transition temperature when no change in the frequency of the laser beam is desired; and a voltage is applied across the crystal to drive it from its paraelectric into its ferroelectric state when a relatively large change in the frequency of the laser beam is desired.Type: GrantFiled: March 18, 1976Date of Patent: November 1, 1977Assignee: The Government of the United States as represented by the Secretary of the ArmyInventors: Lloyd C. Bobb, Kimball Kramer
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Patent number: 4056060Abstract: Armor-piercing rounds having improved penetrators therein providing high axial moments of inertia, and hence, high gyroscopic stability which is attributable to the variously configured non-circular cross-sections of the penetrators.Type: GrantFiled: March 10, 1977Date of Patent: November 1, 1977Assignee: The Government of the United States, as represented by the Secretary of the ArmyInventor: Patrick J. Devine