Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a gene from the Ebola virus.

Abstract: A hypergolic bipropellant. The hypergolic bipropellant includes an ionic liquid fuel and nitric acid, which is operable as an oxidizer. The ionic liquid fuel comprises an open chain amine having at least one quarternized nitrogen and a dicyanamide anion.

Abstract: A polymer is characterized by a repeat unit represented by Structural Formula (I): or a copolymer thereof. A crosslinked polymer characterized by a repeat unit represented by Structural Formula (II), (III), (IV) or (V): or a copolymer thereof, wherein at least one such repeat unit of a first polymer strand is crosslinked with at least one repeat unit of a second polymer strand by at least one bridging unit, the first and second polymer strands and the repeat unit being components of the crosslinked polymer.

Abstract: The present invention provides methods and compositions for treating or preventing bacterial infections, where a pharmaceutically acceptable iron chelator that reduces biological availability of iron for one or more strains of bacteria, such as VK28 or an analog or derivative thereof is administered to a patient in need of treatment. The method also provides methods and compositions where an iron chelator and an antibiotic are administered to a patient in need of treatment for a bacterial infection.

Abstract: Grafted triglycerides comprising an acrylated triglyceride grafted with a fatty acid residue containing 4 to 28 carbon atoms. Also described are methods for making a grafted triglyceride and for curing a material selected from vinyl esters and unsaturated polyesters and mixtures thereof and optionally a reactive diluent. The method includes the steps of mixing a grafted triglyceride of the present invention with a material selected from vinyl esters, unsaturated polyesters and mixtures thereof to form a mixture, and curing the mixture to form a cured resin system. A cured resin system comprising a cured product obtained by the foregoing method and composites containing the cured product and a filler or reinforcing material are also disclosed. This method also includes use of the grafted triglycerides to make toughened resin and composite systems with reduced hazardous air pollutants without significantly reducing the glass transition temperature and significantly increasing the viscosity.

Abstract: A low-defect gallium nitride structure including a first gallium nitride layer comprising a plurality of gallium nitride columns etched into the first gallium nitride layer and a first dislocation density; and a second gallium nitride layer that extends over the gallium nitride columns and comprises a second dislocation density, wherein the second dislocation density may be lower than the first dislocation density. In addition, a method for fabricating a gallium nitride semiconductor layer that includes masking an underlying gallium nitride layer with a mask that comprises an array of columns and growing the underlying gallium nitride layer through the columns and onto said mask using metal-organic chemical vapor deposition pendeo-epitaxy to thereby form a pendeo-epitaxial gallium nitride layer coalesced on said mask to form a continuous pendeo-epitaxial monocrystalline gallium nitride semiconductor layer.

Abstract: The system in at least one embodiment provides a tamper evident specimen sample lock that in a further embodiment includes an embedded storage medium. They system and method in at least one embodiment allows for efficiently and securely creating, maintaining, identifying, tracking, and controlling inventories (either prospective or retrospective) of biological and chemical sample containers and their contents, while eliminating potential loss and degradation associated with handling the samples. The system in at least one embodiment provides a sample container tray or cryogenic box having one or more integrated RFID readers within an associated smart lid that sense RFIDs associated with the individual samples thereby eliminating the need to remove, visually inspect, and/or handle the samples.

Abstract: The present invention provides a system and method for controlling resuscitation in a patient. In at least one embodiment, the invention includes a fluid rate measurer, a controller electrically coupled to the fluid rate measurer, and a pump. The controller is adapted to receive signals from a physiological monitor and controls the pump.

Abstract: An exoskeletal orthosis includes a proximal cuff comprising a hinge along an upper edge of the cuff; an ankle section/footplate; and at least one posterior strut connecting the proximal cuff to the ankle section and foot plate.

Abstract: In one embodiment, an apparatus is characterized by an intubation-tube placement device; and an intubation tube secured to the intubation-tube placement device. In another embodiment, an apparatus is characterized by an intubation-tube placement device; and an anti-perforation device coupled to the intubation-tube placement device. In another embodiment, an apparatus is characterized by an intubation-tube placement device; and at least one tactile-accentuator flap coupled to the intubation-tube placement device. In another embodiment, an apparatus is characterized by an intubation-tube placement device; and a handle affixed to the intubation-tube placement device.

Abstract: A system and method used to create a longitudinal medical record for an injured person that in at least one embodiment begins a location remote from a medical facility. The system includes in at least one embodiment a plurality of mobile computing devices. In at least one embodiment, the mobile computing devices provide an interface for receiving information from a first responder or a medic.

Abstract: A system and method used to create a longitudinal medical record for an injured person that in at least one embodiment begins a location remote from a medical facility. The system includes in at least one embodiment a plurality of mobile computing devices. In at least one embodiment, the mobile computing devices provide an interface for receiving information from a first responder or a medic.

Abstract: A device for measuring the manual dexterity of a subject comprising a central processing unit, a display, storage means, data-entry means and software programming designed to gather the manual dexterity data of a subject is disclosed together with methods of use thereof.

Abstract: A system and process for the aerodynamic stabilization of rocket-assisted artillery projectiles launched from smooth-bore cannons comprises multiple stabilization fins stowed circumferentially and held by a cap until muzzle exit. At muzzle exit, the cap separates and allows the fins to self-deploy using the energy stored within the fin material, which is either shape memory alloy or spring steel. The fins are then locked into place and serve to stabilize the projectile without interfering with the discharge of hot propelling gasses from the rocket nozzle.

Abstract: We disclose Ebola Sudan Boniface virus GP Monoclonal antibodies, epitopes recognized by these monoclonal antibodies, and the sequences of the variable regions of some of these antibodies. Also provided are mixtures of antibodies of the present invention, as well as methods of using individual antibodies or mixtures thereof for the detection, prevention, and/or therapeutic treatment of Ebola Sudan Boniface virus infections in vitro and in vivo.

Abstract: A system and method used to create a longitudinal medical record for an injured person that in at least one embodiment begins a location remote from a medical facility. The system includes in at least one embodiment a plurality of mobile computing devices. In at least one embodiment, the mobile computing devices provide an interface for receiving information from a first responder or a medic.

Abstract: The present invention features immunogenic compositions based on pre-fertilization or post-fertilization antigens expressed in the circulating gametocytes in the peripheral blood of infected persons or on the malaria parastes' stages of develop-ment in the mosquito midgut including extracellular male and female gametes, fertilized zygote and ookinete. The invention also features methods to prevent the transmission of malaria using the immunogenic compositions of the invention.

Abstract: A system for simulating one or more hemorrhages in order to provide a more dynamic and realistic hemorrhage simulation in order to train medical personnel and other critical care givers, such as first responders, medics, and emergency medical technicians (EMTs) on treating hemorrhages. The system includes a reservoir, a flow controller, and at least one conduit connected to at least one simulated wound site wherein the system supplies fluid to the simulated wound site in order to simulate a hemorrhage. The system may further include a plurality of wound sites that have their respective fluid flows controlled by the fluid flow controller. In at least one embodiment, the reservoir and the flow controller are housed within a bag. In at least one embodiment, the system further includes an audio system for providing audio cues to the simulation participants to enhance the realism of the simulation.

Abstract: In one embodiment, an apparatus is characterized by an intubation-tube placement device; and an intubation tube secured to the intubation-tube placement device. In another embodiment, an apparatus is characterized by an intubation-tube placement device; and an anti-perforation device coupled to the intubation-tube placement device. In another embodiment, an apparatus is characterized by an intubation-tube placement device; and at least one tactile-accentuator flap coupled to the intubation-tube placement device. In another embodiment, an apparatus is characterized by an intubation-tube placement device; and a handle affixed to the intubation-tube placement device.

Abstract: We have shown that a single layer of a 3D Zero Index Material (ZIM) has omnidirectional reflection properties. In the range between the electric plasma frequency and the magnetic plasma frequency, ZIM reflect radiation for all angles of incidence and polarization with reflectivities of ˜99%. In addition, with increasing angles of incidence, the reflecting band does not shift in frequency but actually widens. The operational bandwidth can be 100% or greater by increasing the separation between the electric and magnetic plasma frequencies. We have also shown that in the spectral region that allows the omnidirectional gap, ZIM can be used as the cladding of hollow waveguides with better performance than traditional hollow waveguides.