Abstract: A multilayer polypropylene film which includes at least one base layer containing propylene polymer or a propylene polymer mixture and resin, and at least one outer layer containing .alpha.-olefinic polymers having 2 to 10 carbon atoms is disclosed. The resin has a mean molecular weight of.gtoreq.1500. The invention also relates to a process for the production of the multilayer film, and to the use of the film in a twist wrapping process.

Abstract: Compounds of the formula I ##STR1## and the pharmaceutically tolerated salts thereof, are described. A process for their preparation and their use as medicaments in cardiovascular diseases are also described.

Abstract: A thermoplastic polymer/rubber composite body useful as fittings, couplings, sealing elements, rubber bearings and automotive housings comprises a molding of a thermoplastic polymer such as a polyacetal or polyester wherein a rubber copolymer with a crosslinking agent is molded thereon by injection molding, coinjection or coextrusion followed by the vulcanization of the rubber copolymer.

Abstract: For the preparation of predominantly unbranched higher primary alcohols, olefins from the Fischer-Tropsch synthesis are reacted with hydrogen and carbon monoxide in the presence of water and a catalyst which is rhodium, in metallic form or as a compound, and a water-soluble phosphine. The reaction product obtained is hydrogenated. The water-soluble phosphines employed are compounds whose anion is a phosphine containing at least one sulfonated or carboxylated aromatic radical and whose cation is a quaternary ammonium or phosphonium ion.

Abstract: The preparation of L-2-amino-4-methylphosphinobutyric acid (L-PPT) by transamination of (3-carboxy-3-oxopropyl)-methylphosphinic acid with the aid of the L-PPT-specific transaminase from E. coli DH 1 is very much more efficient when the gene coding for this enzyme is isolated, incorporated into a plasmid and then a microorganism is transformed therewith.

Abstract: A process for the chemical synthesis of oligonucleotidesUse of a dansylethoxycarbonyl group as base-labile 5'-hydroxyl protective group in the chemical synthesis of DNA and RNA and suitable synthetic processes.The ease of detection of the dansyl protective group and the ease of elimination from the sugar residue of the nucleotide without side reactions make oligonucleotide synthesis possible with high yields in very small quantities.

Abstract: PNA synthesis using an amino protective group which is labile to weak acids.

Abstract: Polymer blends obtainable by thermal treatment, at not less than 150.degree. C., of a mixture containing at least one high-performance polymer and from 15 to 99 parts by weight or preferably from 40 to 90 parts by weight and particularly preferably from 55 to 75 parts by weight, of a polymer containing sulfoxide groups, and crosslinked or partly crosslinked polymer blend obtainable by thermal treatment, at not less than 150.degree. C., of a mixture containing at least one of the high-performance polymers polyesters, partly fluorinated polymers, polyethersulfones, polysulfones, polyetherimides, polyamidoimides or polyacetals and at least one polymer containing sulfoxide groups, are distinguished by high thermal and chemical stability. Polymers containing sulfoxide groups are polyarylene sulfoxides, in particular polyphenylene sulfoxide. The polymer blends are used for the production of fibers, films or shaped articles.

Abstract: The present invention relates to a process for preparing a high-T.sub.c superconductor as a precursor material for the oxide-powder-in-tube method, which involves mixing the oxides of the elements Bi, Sr, Ca and Cu and completely melting them at temperatures of .gtoreq.1000.degree. C., then casting the melt onto a substrate which is kept at room temperature, and disintegrating the cooled melt block and grinding it into a powder.

Abstract: The invention relates to an electroluminescence device having at least one light-emitting layer which comprises conjugated, stiff-chain polymers which are soluble in organic solvents, wherein the emitted electroluminescence is polarized and the intensity of the light which is polarized parallel to the longitudinal axis of the substrate is at least three times the intensity polarized perpendicular thereto.

Abstract: Enzymatic RNA molecules have been designed that cleave mutant N-ras mRNA, preferably at a NUX cleavage site (N=any base, X=A, C or U). Preferred ribozymes have nucleotide sequences 5'-CCAACACCUGAUGAGCGUUAGCGAAACCUGCU-3' or 5'-UCCCAACCUGAUGAGCGUUAGCGAAACACCUG-3' (SEQ ID NOS:1 and 2), and derivatives thereof. The present invention also provides pharmaceuticals containing such molecules and the use of such molecules for the preparation of pharmaceuticals for the treatment of diseases involving abnormal cell growth and/or differentiation.

Abstract: The invention relates to a composition which is a pharmaceutical combination preparation comprising a compound which has an acetylcholinesterase-inhibitory action or exhibits muscarinergic action and a compound which increases the endogenous extracellular adenosine level, wherein the combination preparation is suitable for the treatment of dementia. The invention further relates to a process for the production of the combination preparation. The invention additionally relates to a process for treating patients in need of suitable therapy with the combination preparation.

Abstract: A fiber-reinforced, tubular food casing based on regenerated cellulose, which is produced using an amount of viscose solution which is decreased by 10 to 30% in comparison with the standard casing at a spinning speed increased by at least 25%.

Abstract: Monoclonal antibodies for selective immunological determination of high molecular weight, intact laminin forms in body fluids. The present invention relates to monoclonal antibodies for the selective immunological determination of high molecular weight forms of laminin in body fluids, to a process for preparing these antibodies, and to their use for diagnosing diseases. The antibodies according to the invention preferably bind to intact, native laminin, in particular to the structures of the laminin P1 domain of the laminin which are folded in a native manner.

Abstract: The invention relates to compounds of the formula I ##STR1## where R.sup.1 is H, alkyl, acyl, aryl, or a phosphate residue; R.sup.2 is H, OH, alkoxy, NH.sub.2, or halogen; B is a base customary in nucleotide chemistry; a is O or CH.sub.2 ; n is an integer from 1 to 100; W=O, S or Se; V=O, S, or NH; Y=O, S, NH, or CH.sub.2 ; Y'=O, S, NH, or alkylene; X=OH or SH; U=OH, SH, SeH, alkyl, alkoxy, aryl, aryloxy, or amine, and Z=OH, SH, SeH, an optionally substituted radical from the group comprising alkyl, aryl, heteroaryl, alkoxy, or amino, or a group which favors intracellular uptake or serves as the label of a DNA probe or attacks the target nucleic acid during hybridization, where if Z=OH, SH, CH.sub.3, or OC.sub.2 H.sub.5, at least one of the groups X, Y, Y', V, or W is not OH or O or R.sup.1 is not H; a process for their preparation and their use as inhibitors of gene expression, as probes for detecting nucleic acids and as aids in molecular biology.

Abstract: The invention provides the promoter of the cdc25B gene, a process for finding cdc25B promoters and methods for using the promoters for preparing a pharmaceutical.

Abstract: Methylphosphonic acid esters, processes for their preparation, and their useFrom the compounds of the formula I, ##STR1## in which the substituents R', Y, W and R have the meanings mentioned, in vivo have the action of the active compound radical W together with improved pharmacokinetics.

Abstract: The blends, according to the invention, of polyethylene and polypropylene having improved notched impact strength are distinguished by the fact that they containa) from 36 to 64% by weight of isotactic propylene homopolymer,b) from 35 to 63% by weight of high density polyethylene (HDPE) andc) from 1 to 10% by weight of a random copolymer comprising from 75 to 85% by weight of ethylene units and from 15 to 25% by weight of propylene units,all stated percentages by weight being based on the total weight of the respective blend.

Abstract: According to certain embodiments, the invention relates to a method of producing antibodies employing an immunoconjugate produced by conjugating at least one membrane-anchoring compound with at least one partial sequence of a viral, bacterial, or protoral protein. The immunoconjugate has the advantage that it can be stored for a very long time even without cooling. According to certain embodiments, the invention relates to an immunoconjugate for the specific induction of cytotoxic T-lymphocytes which comprises a conjugate from at least one membrane anchor compound and a protein, containing at least one killer T-cell epitope, of a virus, a bacterium, a parasite or a tumor antigen, or at least one partial sequence containing at least one killer T-cell epitope of a viral, bacterial or parasite protein or of a tumor antigen.

Abstract: A blend of at least one fluorine polymer, at least one oxidized polyarylene sulfide, at least one polyarylene sulfide and, if required, conventional additives results in a reduction in the expulsion of the oxidized polyarylene sulfides in gaseous form in the production of shaped articles from this blend, so that no cracks occur in the shaped article and problem-free processing by a cutting method is permitted.