Abstract: A combined preparation for simultaneous combined, simultaneous separate, or sequential use in the therapy of prophylaxis of disorders associated with undesirable high levels of TNF, e.g. septic or endotoxic shock and immunoregulatory and inflammatory disorders, which comprises an antibody to TNF or a TNF binding fragment thereof and a xanthine derivative. Particular preferred xanthine derivatives are 3,7-dimethyl-1(5-oxo-hexyl)xanthine (known as Pentoxifylline or TRENTAL) and 1-(5-hydroxy-5-methylhexyl)-3-methylxanthine and similar compounds. The anti-TNF antibody or fragment is preferably monospecific especially a humanized recombinant antibody or fragment.

Abstract: The invention relates to a composition comprising between 30 and 95% by volume of aerogel particles and at least one aqueous binder, where the particle diameter of the aerogel particles is less than 0.5 mm and the aerogel particles preferably have hydrophobic surface groups, a process for the preparation thereof, and the use thereof.

Abstract: This invention relates to an electrically conductive shaped article made from thermoplastic materials which are reinforced with glass and steel fibers wherein said fibers are incorporated into the thermoplastic material by pultrusion. The amount of glass fibers incorporated into the thermoplastic material is such that the specific conductivity is at least 10% greater than in a shaped article in which the glass fibers are replaced by thermoplastic material. The shaped article can be used for shielding an article from electromagnetic radiation.

Abstract: The use of conjugated compounds which contain two or more pyrimidine rings as part of the conjugated system as electroluminescence materials. The conjugated compounds containing pyrimidine rings have a high thermal stability and a high photostability. They are partially soluble in acids, which also makes possible processing from solution, as well as by vapor deposition.

Abstract: A process is described for preparing polyols in the form of bifunctional aromatic polyester alcohols from PET wastes and wastes from PET production. The process comprises dissolving the PET wastes in diethylene glycol (DEG), with the ratio of wastes to DEG being selected in such a way that the polyester alcohol obtained after the subsequent transesterification has a hydroxyl number (OHN) greater than 700 mg KOH/g, transesterifying the wastes dissolved in DEG and, if required or if desired, freed of solids, using known transesterification catalysts, with the ethylene glycol (EG) liberated in the process being at least partially distilled off, and distilling off free DEG at a temperature of below 140.degree. C. from the transesterification product at equilibrium until a polyester alcohol having an OHN of 260-500 mg KOH/g is obtained.

Abstract: In order to produce tubular moldings of high-temperature superconducting material based on oxides of bismuth, calcium, strontium, copper and optionally lead, a homogeneous melt of the oxide mixture in a predefined stoichiometry having temperatures from 900 to 1300.degree. C. is made to flow into a casting zone. The casting zone, as a function of its internal diameter, rotates at from 200 to 1500 rpm about its axis which is inclined by at least 15.degree. with respect to the horizontal. The solidified molding is taken from the casting zone and annealed for from 4 to 150 hours at from 700 to 900.degree. C. in an oxygen-containing atmosphere.

Abstract: Use of a dansylethoxycarbonyl group as base-labile 5'-hydroxyl protective group in the chemical synthesis of DNA and RNA and suitable synthetic processes.The ease of detection of the dansyl protective group and the ease of elimination from the sugar residue of the nucleotide without side reactions make oligonucleotide synthesis possible with high yields in very small quantities.

Abstract: 1-Fluoro-5,6,7,8-tetrahydroisoquinoline derivatives, and their use in liquid-crystalline mixtures1-Fluoro-5,6,7,8-tetrahydroisoquinoline derivatives of the formula (I)R.sup.1 ( --M.sup.1).sub.a (--A.sup.1 --M.sup.2).sub.b (--A.sup.2 --M.sup.3).sub.c --B(--M.sup.4 --A.sup.3).sub.d (--M.sup.5 --A.sup.4).sub.e (--M.sup.6 .sub.f --R.sup.2 (I)in which the symbols and indices have the following meanings:the group B is ##STR1## R.sup.1 and R.sup.2 are, for example, alkyl radicals having 1 to 20 carbon atoms;M.sup.1, M.sup.2, M.sup.3, M.sup.4, M.sup.5 and M.sup.6 are, for example, --O--, --CO--O--, --O--CO-- or a single bond;A.sup.1, A.sup.2, A.sup.3 and A.sup.4 are, for example, 1,4-phenylene, pyrimidine-2,5-diyl or trans-1,4-cyclohexylene, anda, b, c, d, e and f are zero or one, with the proviso that the sum of b, c, d and e is 0, 1 or 2.

Abstract: Novel polyene antibiotics, 3874 H1 to H6, processes for their preparation and use which are suitable for treating fungal diseases, trichomonad diseases, and for treating diseases associated with an increased steroid concentration.

Abstract: The present invention relates to hydantoin derivatives of the formula I ##STR1## and which are intermediates for the preparation of pharmaceutical active compounds, their preparation and their use in the preparation of the active compounds.

Abstract: The invention relates to 4-Amino-2-ureidopyrimidine-5-carboxamides of the formula I ##STR1## in which R.sup.1 is H or (C.sub.1 -C.sub.8)-alkyl, where one or more H can be replaced by F; R.sup.2 is selected from the group consisting of F, Cl, Br, H, -O-(C.sub.1 -C.sub.8)-alkyl, and -S-(C.sub.1 -C.sub.8)-alkyl, where the alkyl groups have one or more H replaced by F; R.sup.3 is -O-(C.sub.1 -C.sub.8)-alkyl or -S-(C.sub.1 -C.sub.8)-alkyl, where the alkyl groups have one or more H replaced by F; or R.sup.2 and R.sup.3 together form -O-(C.sub.1 -C.sub.5)-alkylene-O-, where the alkylene portion has one or more H replaced by F; and their physiologically tolerable salts. The invention further provides processes for preparing the compounds of formula I. The compounds are suitable for the treatment of disorders of lipid metabolism.

Abstract: A process is described for preparing oligonucleotides by solid phase synthesis in which exocyclic amino groups present on nucleobases are protected with cyclic diacyl groups, which can be deprotected in the presence of a strong, nonnucleophilic base. Novel intermediates employing the cyclic diacyl protecting groups are also described.

Abstract: There are described compounds of the formula I ##STR1## in which R.sup.1 is (C.sub.1 -C.sub.10)-alkyl, (C.sub.1 -C.sub.8)-alkanoyl, (C.sub.6 -C.sub.10)-aryl or Het, each of which can be substituted by halogen, --OH, --NH.sub.2, --NH--CO--R.sup.7, --O--CO--R.sup.7 and --N--(R.sup.8).sub.2 where R.sup.7 =(C.sub.1 -C.sub.6)-alkyl and R.sup.8, independently of one another, is hydrogen or (C.sub.1 -C.sub.2)-alkyl or in which R.sup.1 is the radical of the formula II ##STR2## in which n is an integer from 3 to 10, m is zero to 3, R.sup.6, independently of one another, is (C.sub.1 -C.sub.6)-alkyl which is optionally substituted by halogen or --NH--CO--R.sup.7, where R.sup.7 =(C.sub.1 -C.sub.6)-alkyl, and X is absent or is (C.sub.1 -C.sub.10)-alkyl, and R.sup.2, R.sup.3, R.sup.4 or R.sup.5, independently of one another, are hydrogen, (C.sub.1 -C.sub.5) -alkyl, lithium, sodium, potassium or Si(R), where R=(C.sub.1 -C.sub.

Abstract: A composite film is described which has at least one base layer which predominantly comprises polypropylene, and at least one top layer. The top layer is sealable and comprises a homopolymer of an olefin. A process for producing the composite film, the top layer olefin homopolymer and packaging material made from the film also are described.

Abstract: A process for separating off phosphine oxides and alkylarylphosphines from an organic reaction mixture of a homogeneous hydroformylation carried out with the use of a catalyst system, which reaction mixture contains organometallic complex compounds and, in a molar excess, ammonium salts of aromatic phosphines as ligands comprising subjecting the organic reaction mixture to an extraction treatment with a 0.001-0.5% strength by weight of an alkali metal hydroxide or alkaline earth metal hydroxide solution and separating off the aqueous phase containing the phosphine oxides and alkylarylphosphines to decrease markedly the concentration of the phosphine oxides and alkylarylphosphines in the hydroformylation mixture, which process is particularly suitable for continuously operated hydroformylations.

Abstract: The invention relates to a material for producing electrically conducting connections in thermoplastic moldings, wherein the material contains a thermoplastic containing 0.5 to 30% by volume of conductive fibers having a length of 5 to 20 mm and a diameter of 5 to 100 .mu.m and has a volume resistivity of less than 1 ohm.cm.

Abstract: Increased synergistic herbicidal actions are obtained using combinations of the herbicides A and B, where A denotes substituted N-phenoxysulfonyl-N'-(4,6-disubstituted pyrimid-2-yl)ureas of the formula (I) as claimed in claim 1, and B denotes quinchlorac, molinate, thiobencarb, butachlor, pretilachlor, MON 7200, mefenacet, fenoxaprop-ethyl, dimepiperate and/or NTN-901.

Abstract: Sausage casings of starch which can be processed like a thermoplastic and to processes for the production and use thereof. The sausage casing comprises a thermoplastic starch which is comprised of natural starch which has been converted into an amorphous state.

Abstract: A water-soluble catalyst composition comprising rhodium complexes containing diphosphine ligands, wherein the diphosphine ligands present are compounds of the formula ##STR1## where R.sup.1 is selected from the group consisting of carboxylate (COO.sup.-), sulfonate (SO.sub.3.sup.-), phosphonate (PO.sub.3.sup.2-) and 2-amino ethanebisphosphonate ?NH--CH.sub.2 --CH(PO.sub.3.sup.2-).sub.2 !, R.sup.2 is selected from the group consisting of a straight-chain alkylene of 1 to 8 carbon atoms, an oxygen-containing alkylene of 2 to 6 carbon atoms, cycloalkylene of 3 to 10 carbon atoms and a member of the formulae II, III, IV or V ##STR2## a, b, c, d, e, f, g, h, k and l are individually 0 to 1, where at least one of a, b, c, d, e, f, g, h, k or l has to be equal to 1, x(s) are individually 0 or 1, y is an integer of 1 to 24, R.sup.3 and R.sup.

Abstract: Use of xanthine derivatives for the treatment of nerve damage following an interruption in blood circulation.The invention relates to the use of xanthine derivatives of the formula I ##STR1## in which R.sup.2 is a (C.sub.1 -C.sub.4)-alkyl group and at least one of the symbols R.sup.1 and R.sup.3 is a radical of the formula II or III ##STR2## in which A is CHOH, CO or dioxolane, R.sup.4 is a hydrogen atom or a (C.sub.1 -C.sub.4)-alkyl group and n is 0 to 5, and in which R.sup.5 and R.sup.6 are hydrogen atoms or (C.sub.1 -C.sub.4)-alkyl groups or, together with the nitrogen atom to which they are bonded, form a 5- to 7-membered ring, it being possible for one carbon atom to be replaced by an oxygen or nitrogen atom, m is 1 or 2 and the other radical R.sup.1 or R.sup.3, if appropriate, is a hydrogen atom, a (C.sub.1 -C.sub.6)-alkyl group or a (C.sub.3 -C.sub.