Patents Assigned to Ikonisys Inc.
  • Publication number: 20080238674
    Abstract: A system for automatically locating positions on an object and uniquely identifying the object employing an electronic tag positioned in or on the object. The system utilizes a plurality of sensors to locate the electronic tag and identify the object, and triangulation techniques to locate positions on the object where the object may be manipulated according to instructions coded with respect to the positions. Advantageously, the present invention may be used for automatically locating specimens on a microscope slide without regards to their positions on the slide, and for uniquely labeling a microscope slide.
    Type: Application
    Filed: March 29, 2007
    Publication date: October 2, 2008
    Applicant: Ikonisys, Inc.
    Inventors: Triantafyllos P. Tafas, Youngmin Kim
  • Publication number: 20080231973
    Abstract: A mechanism is disclosed for incorporation into automatic microscope which permits the interchanging of optical path components such as objective lens assemblies, filters, and imaging devices. The mechanism features good placement accuracy and repeatability to permit the maintenance of system calibrations.
    Type: Application
    Filed: August 2, 2007
    Publication date: September 25, 2008
    Applicant: Ikonisys, Inc.
    Inventor: Wei Guo
  • Patent number: 7424165
    Abstract: A method and system for auto-focusing is disclosed where the number of the fractal pixels having a fractal dimension within a predetermined range is determined. The focused image is determined by adjusting the image to maximize the fractal pixel count. Alternatively, the focused image may be selected from a set of images, the image having the largest fractal pixel count selected as the focused image.
    Type: Grant
    Filed: October 5, 2004
    Date of Patent: September 9, 2008
    Assignee: Ikonisys, Inc.
    Inventor: Joel M. Recht
  • Publication number: 20080213902
    Abstract: Improvements in FISH staining employing a microscope slide holder which allows for batch processing of slides in the hybridization process.
    Type: Application
    Filed: August 3, 2007
    Publication date: September 4, 2008
    Applicant: Ikonisys, Inc.
    Inventors: Ilia Ichetovkin, Michael Kilpatrick
  • Publication number: 20080212172
    Abstract: An embodiment is disclosed for performing the image processing for analyzing the results of a fluorescence in situ hybridization (FISH) microscopic automated sample analysis to determine specific chromosomal characteristics.
    Type: Application
    Filed: October 26, 2007
    Publication date: September 4, 2008
    Applicant: Ikonisys, Inc.
    Inventors: Yanning Zhu, Triantafyllos Tafas, Youngmin Kim, Xiuzhong Wang
  • Publication number: 20080213824
    Abstract: Improvements in FISH staining employing an aqueous acetonitrile/dimethylsulfoxide mixture in a fluorophore coupling reaction.
    Type: Application
    Filed: August 3, 2007
    Publication date: September 4, 2008
    Applicant: IKONISYS, INC.
    Inventor: Ilia Ichetovkin
  • Publication number: 20080212865
    Abstract: An embodiment is disclosed for performing the image processing for analyzing the results of a fluorescence in situ hybridization (FISH) microscopic automated sample analysis to determine specific chromosomal characteristics.
    Type: Application
    Filed: August 2, 2007
    Publication date: September 4, 2008
    Applicant: Ikonisys, Inc.
    Inventors: Yanning Zhu, Triantafyllos Tafas, Youngmin Kim, Xiuzhong Wang
  • Publication number: 20080213769
    Abstract: Automated methods for detecting cancer and related hyperplasias in biological samples.
    Type: Application
    Filed: October 26, 2007
    Publication date: September 4, 2008
    Applicant: Ikonisys, Inc.
    Inventors: Triantafyllos P. Tafas, Petros Tsipouras, Michael Kilpatrick, Gary Sarkis
  • Publication number: 20080206774
    Abstract: In various embodiments methods for automated screening for gene amplification in biological tissue samples using an automated fluorescence microscope to analyze fluorescence in situ hybridized samples are provided. Various additional embodiments provide methods of high throughput screening for gene amplification.
    Type: Application
    Filed: March 19, 2008
    Publication date: August 28, 2008
    Applicant: IKONISYS, INC.
    Inventors: Triantafyllos P. Tafas, Michael Kilpatrick, Xiuzhong Wang, Youngmin Kim, Michael Thomas, Petros Tsipouras
  • Publication number: 20080198450
    Abstract: A microscope slide mount capable of z-axis movement.
    Type: Application
    Filed: August 2, 2007
    Publication date: August 21, 2008
    Applicant: Ikonisys, Inc.
    Inventors: Wei Guo, Triantafyllos Tafas
  • Publication number: 20080199948
    Abstract: A method for recognizing an object in an image is disclosed wherein a fractal map of the image is generated by estimating the fractal dimension of each pixel in the image. The fractal map may be segmented by thresholding and locations of candidate objects are determined. The pixel value of the image pixel corresponding to the same location where the candidate object is found in the fractal map may be compared to a threshold value. If the pixel value is greater than the threshold value, the candidate object is recognized as a valid object.
    Type: Application
    Filed: March 21, 2008
    Publication date: August 21, 2008
    Applicant: Ikonisys, Inc.
    Inventors: Triantafyllos Tafas, Michael Kilpatrick, Petros Tsipouras
  • Publication number: 20080187464
    Abstract: An apparatus for the feeding of microscope slides from a storage device to a slide stage.
    Type: Application
    Filed: August 3, 2007
    Publication date: August 7, 2008
    Applicant: Ikonisys, Inc.
    Inventors: Wei Guo, Yash Agarwal, Youngmin Kim, Triantafyllos Tafas
  • Publication number: 20080182253
    Abstract: Automated methods for detecting cancer and related hyperplasias in biological samples.
    Type: Application
    Filed: October 25, 2007
    Publication date: July 31, 2008
    Applicant: Ikonisys, Inc.
    Inventors: Triantafyllos P. Tafas, Petros Tsipouras, Michael Kilpatrick, Gary Sarkis
  • Publication number: 20080182244
    Abstract: A method for determining viable normal blastomeres for implantation entailing labeling the blastomere with an antibody to hyperglycoslyated hCG and determining the binding of chromosomal probes directed to chromosomal regions of the chromosome.
    Type: Application
    Filed: August 3, 2007
    Publication date: July 31, 2008
    Applicant: Ikonisys, Inc.
    Inventors: Triantafyllos Tafas, Ilia Ichetovkin, Michael Kilpatrick, Petros Tsipouras
  • Publication number: 20080180794
    Abstract: A light-tight enclosure system for housing an automated microscope.
    Type: Application
    Filed: August 2, 2007
    Publication date: July 31, 2008
    Applicant: Ikonisys, Inc.
    Inventors: Triantafyllos Tafas, Yash Agarwal, Youngmin Kim, Wei Guo, Richard Eberle, Joseph Turgeon, Michael Kilpatrick, Petros Tsipouras
  • Publication number: 20080180790
    Abstract: An automatic microscope is disclosed which incorporates dynamic scanning of the microscope slide and other interchangeable optical path components.
    Type: Application
    Filed: August 3, 2007
    Publication date: July 31, 2008
    Applicant: Ikonisys, Inc.
    Inventors: Triantafyllos Tafas, Yanning Zhu
  • Publication number: 20080131026
    Abstract: A method for recognizing an object in an image is disclosed wherein a fractal map of the image is generated by estimating the fractal dimension of each pixel in the image. The fractal map may be segmented by thresholding and locations of candidate objects are determined. The pixel value of the image pixel corresponding to the same location where the candidate object is found in the fractal map may be compared to a threshold value. If the pixel value is greater than the threshold value, the candidate object is recognized as a valid object.
    Type: Application
    Filed: February 11, 2008
    Publication date: June 5, 2008
    Applicant: Ikonisys, Inc.
    Inventor: Joel M. RECHT
  • Publication number: 20080131064
    Abstract: The present invention provides devices and methods for detection of particles, such as biological cells, in samples using a photosensitive waveguide. The photosensitive waveguide changes its transmissivity in a detectable manner in response to controlling radiation emitted from the particles. In preferred embodiments, the waveguide is two-dimensional and the position of the particles as well as their presence is obtained by scanning the waveguide in two non-parallel directions. The provided devices are preferably used to locate labeled cells. The present invention also includes control systems and methods for detecting and locating cells using the devices provided.
    Type: Application
    Filed: March 27, 2007
    Publication date: June 5, 2008
    Applicant: IKONISYS, INC.
    Inventors: Petros Tsipouras, Triantafyllos Tafas
  • Patent number: 7373018
    Abstract: A method for recognizing an object in an image is disclosed wherein a fractal map of the image is generated by estimating the fractal dimension of each pixel in the image. The fractal map may be segmented by thresholding and locations of candidate objects are determined. The pixel value of the image pixel corresponding to the same location where the candidate object is found in the fractal map may be compared to a threshold value. If the pixel value is greater than the threshold value, the candidate object is recognized as a valid object.
    Type: Grant
    Filed: May 7, 2007
    Date of Patent: May 13, 2008
    Assignee: Ikonisys, Inc.
    Inventor: Joel Recht
  • Publication number: 20080106743
    Abstract: The contrast of an image produced by epifluorescence microscopy may be increased by placing a dichroic reflector behind the sample. The dichroic reflector reflects the emission light emitted by the fluorescent tags in the sample back through the objective lens while allowing the shorter wavelength excitation light to pass through the sample holder.
    Type: Application
    Filed: January 7, 2008
    Publication date: May 8, 2008
    Applicant: IKONISYS, INC.
    Inventors: Triantafyllos Tafas, Petros Tsipouras