Abstract: A system for automatically locating positions on an object and uniquely identifying the object employing an electronic tag positioned in or on the object. The system utilizes a plurality of sensors to locate the electronic tag and identify the object, and triangulation techniques to locate positions on the object where the object may be manipulated according to instructions coded with respect to the positions. Advantageously, the present invention may be used for automatically locating specimens on a microscope slide without regards to their positions on the slide, and for uniquely labeling a microscope slide.
Abstract: A mechanism is disclosed for incorporation into automatic microscope which permits the interchanging of optical path components such as objective lens assemblies, filters, and imaging devices. The mechanism features good placement accuracy and repeatability to permit the maintenance of system calibrations.
Abstract: A method and system for auto-focusing is disclosed where the number of the fractal pixels having a fractal dimension within a predetermined range is determined. The focused image is determined by adjusting the image to maximize the fractal pixel count. Alternatively, the focused image may be selected from a set of images, the image having the largest fractal pixel count selected as the focused image.
Abstract: An embodiment is disclosed for performing the image processing for analyzing the results of a fluorescence in situ hybridization (FISH) microscopic automated sample analysis to determine specific chromosomal characteristics.
Type:
Application
Filed:
October 26, 2007
Publication date:
September 4, 2008
Applicant:
Ikonisys, Inc.
Inventors:
Yanning Zhu, Triantafyllos Tafas, Youngmin Kim, Xiuzhong Wang
Abstract: An embodiment is disclosed for performing the image processing for analyzing the results of a fluorescence in situ hybridization (FISH) microscopic automated sample analysis to determine specific chromosomal characteristics.
Type:
Application
Filed:
August 2, 2007
Publication date:
September 4, 2008
Applicant:
Ikonisys, Inc.
Inventors:
Yanning Zhu, Triantafyllos Tafas, Youngmin Kim, Xiuzhong Wang
Abstract: In various embodiments methods for automated screening for gene amplification in biological tissue samples using an automated fluorescence microscope to analyze fluorescence in situ hybridized samples are provided. Various additional embodiments provide methods of high throughput screening for gene amplification.
Type:
Application
Filed:
March 19, 2008
Publication date:
August 28, 2008
Applicant:
IKONISYS, INC.
Inventors:
Triantafyllos P. Tafas, Michael Kilpatrick, Xiuzhong Wang, Youngmin Kim, Michael Thomas, Petros Tsipouras
Abstract: A method for recognizing an object in an image is disclosed wherein a fractal map of the image is generated by estimating the fractal dimension of each pixel in the image. The fractal map may be segmented by thresholding and locations of candidate objects are determined. The pixel value of the image pixel corresponding to the same location where the candidate object is found in the fractal map may be compared to a threshold value. If the pixel value is greater than the threshold value, the candidate object is recognized as a valid object.
Type:
Application
Filed:
March 21, 2008
Publication date:
August 21, 2008
Applicant:
Ikonisys, Inc.
Inventors:
Triantafyllos Tafas, Michael Kilpatrick, Petros Tsipouras
Abstract: A method for determining viable normal blastomeres for implantation entailing labeling the blastomere with an antibody to hyperglycoslyated hCG and determining the binding of chromosomal probes directed to chromosomal regions of the chromosome.
Type:
Application
Filed:
August 3, 2007
Publication date:
July 31, 2008
Applicant:
Ikonisys, Inc.
Inventors:
Triantafyllos Tafas, Ilia Ichetovkin, Michael Kilpatrick, Petros Tsipouras
Abstract: An automatic microscope is disclosed which incorporates dynamic scanning of the microscope slide and other interchangeable optical path components.
Abstract: A method for recognizing an object in an image is disclosed wherein a fractal map of the image is generated by estimating the fractal dimension of each pixel in the image. The fractal map may be segmented by thresholding and locations of candidate objects are determined. The pixel value of the image pixel corresponding to the same location where the candidate object is found in the fractal map may be compared to a threshold value. If the pixel value is greater than the threshold value, the candidate object is recognized as a valid object.
Abstract: The present invention provides devices and methods for detection of particles, such as biological cells, in samples using a photosensitive waveguide. The photosensitive waveguide changes its transmissivity in a detectable manner in response to controlling radiation emitted from the particles. In preferred embodiments, the waveguide is two-dimensional and the position of the particles as well as their presence is obtained by scanning the waveguide in two non-parallel directions. The provided devices are preferably used to locate labeled cells. The present invention also includes control systems and methods for detecting and locating cells using the devices provided.
Abstract: A method for recognizing an object in an image is disclosed wherein a fractal map of the image is generated by estimating the fractal dimension of each pixel in the image. The fractal map may be segmented by thresholding and locations of candidate objects are determined. The pixel value of the image pixel corresponding to the same location where the candidate object is found in the fractal map may be compared to a threshold value. If the pixel value is greater than the threshold value, the candidate object is recognized as a valid object.
Abstract: The contrast of an image produced by epifluorescence microscopy may be increased by placing a dichroic reflector behind the sample. The dichroic reflector reflects the emission light emitted by the fluorescent tags in the sample back through the objective lens while allowing the shorter wavelength excitation light to pass through the sample holder.