Abstract: A reciprocating drive apparatus (10) comprises a housing (12) and a mandrel (14), wherein the mandrel (14) and the housing (12) are configurable to be rotated relative to each other. The apparatus (10) further comprises a reciprocating piston (16) mounted within a piston housing (18) to define a piston chamber (20a), wherein the piston (16) is moveable in reverse first and second axial directions (A,B), and a rotary valve assembly (24) comprising a valve inlet (28) for communicating with a pressure region (P) and a valve exhaust (30) for communicating with an exhaust region (E). The rotary valve assembly (24) is operated by relative rotation between the mandrel (14) and the housing (12) to be cyclically reconfigured between a pressure configuration and an exhaust configuration.

Abstract: Apparatuses, methods, and systems are disclosed for uplink/downlink scheduling. One apparatus includes a processor and a memory that stores code executable by the processor. The code, in various embodiments, determines an uplink schedule for data to be transmitted from a user equipment. In a further embodiment, the code determines a downlink schedule for data to be provided to the user equipment. The apparatus may include a transmitter that provides an uplink grant message to the user equipment to initiate an uplink transmission based on the uplink schedule. In certain embodiments, the uplink schedule and the downlink schedule are determined without using a predefined split pattern for uplink and downlink transmission.

Abstract: The present invention relates to a method for preparing a stabilised crystalline A/M/X material comprising an oxide of formula [Z]pOq and a compound of formula [A]a[M]b[X]c, wherein [Z] comprises at least one element Z capable of forming an oxide with a band gap of at least 3 eV; p and q are positive numbers; [A] comprises one or more A cations; [M] comprises one or more M cations; [X] comprises one or more X anions; a is an integer from 1 to 6; b is an integer from 1 to 6; and c is an integer from 1 to 18. Often, the stabilised crystalline A/M/X material is a perovskite. The invention also provides a stabilised crystalline A/M/X material, which can be produced by the process of the invention. The invention further provides materials and devices containing the stabilised crystalline A/M/X material of the invention.

Abstract: The present invention provides phagemid vectors and associated phagemid particles for cancer treatment, and in particular, to the use of novel phagemid particles and associated expression systems for the treatment, prevention, amelioration, or management of cancer. In particular, the invention relates to the use of phagemid particles and expression systems for the delivery of transgenes encoding cytokines, for the treatment, prevention, amelioration, or management of cancer. The invention also extends to the use of phagemid particles and expression systems for the delivery of transgenes, and for the combination of such treatment with the use of adoptively transferred T cells, for the treatment, prevention, amelioration, or management of cancer.

Abstract: The present invention relates to a semiconductor device comprising a semiconducting material, wherein the semiconducting material comprises a compound comprising: (i) one or more first monocations [A]; (ii) one or more second monocations [BI]; (iii) one or more trications [BIII]; and (iv) one or more halide anions [X]. The invention also relates to a process for producing a semiconductor device comprising said semiconducting material. Also described is a compound comprising: (i) one or more first monocations [A]; (ii) one or more second monocations [BI] selected from Cu+, Ag+ and Au+; (iii) one or more trications [BIII]; and (iv) one or more halide anions [X].

Abstract: The invention relates to RNA constructs, and particularly, although not exclusively, to mRNA constructs and saRNA replicons and to nucleic acids and expression vectors encoding such RNA constructs. The invention extends to the use of such RNA constructs in therapy, for example in treating diseases and/or in vaccine delivery. The invention extends to pharmaceutical compositions comprising such RNA constructs, and methods and uses thereof.

Abstract: The sensor device (10) comprises a sensor module (101) and an input-output interface (105) arranged to send and receive data over a bidirectional line (11). A buffer (103) is arranged to store time-series sensor data. A programmable and erasable nonvolatile memory (109) receives and stores an identifier for the sensor device (10). The sensor module (101) generates an inference using the sensor data. The sensor device (10) is arranged to switch between sending, over the bidirectional line (11), data sensed by the sensor module (101) and the generated inference. The sensor device (10) is a single-wire sensor device. The input-output interface (105) is a single-wire input-output interface. The sensor module (101) is a motion, electropotential, electroimpedance, chemical, or optical sensor module. The sensor device (10) is provided in a system comprising a master device. The sensor device (10) or system is incorporated into a wearable article.

Abstract: A disclosed apparatus and method provide recommendations for products which a customer may need to order and/or items which the customer may have forgotten to order. An exemplary recommendation unit can communicate with a product information database, a product similarity database, a customer purchase history database and a customer order database. The recommendation unit includes a determining unit to store a determined similarity of products in the product similarity database, a training unit to train a model based on information about products previously purchased by each customer and information about at least one determined similarity as stored in the product similarity database, a similarity unit to generate at least one product similar to at least one product to be purchased by a customer based on information about a current order of a customer, and a calculating unit to calculate a probability that a customer forgot to add a similar product.

Abstract: An implantable intravascular pressure sensor comprising a first transducer arranged to provide a pressure dependent signal in response to alternating electrical signals of a first frequency band, a second transducer arranged to provide a reference signal in response to alternating electrical signals of a second frequency band different from the first frequency band and an antenna coupling for sending and receiving said signals.

Abstract: An image of a garment is obtained (101). The garment comprises a marker located on an outside surface of the garment. The marker comprises a code string identifying the garment encoded into a visual symbol. The image is processed to generate a data string representing the visual symbol (102). The data string is used to access activity data associated with a sensor of the garment identified by the code string. The system comprises the garment and one or more electronic devices operable to perform the method.

Abstract: A retrieval controller is disclosed for identifying an item to be retrieved from a flat storage surface by a robot for identifying one item, amongst items stored on a common surface that can be retrieved by a robot equipped with a lateral-motion gripper. The retrieval controller includes: a depth map computing unit configured to establish a global coordinate system, and establish an orthonormal set of basis vectors u, v and w defined in the global coordinate system, where w is approximately orthogonal to the surface that the items are stored on; a vector determination unit; an item selection unit; and a robot instructing unit configured to instruct the robot to retrieve the item based on uv coordinates of one or more w-aligned edges having associated quadrilateral-based, right prisms which do not have interiors that intersect any right, enclosing prisms selected by the item selection unit.

Abstract: A load handling device is disclosed for retrieving, transporting, and delivering containers in a storage system having a grid structure formed of two substantially perpendicular sets of rails or tracks located above stacks of containers. An exemplary load handling device can include a wheel assembly, a container receiving space, and a plurality of vehicle modules. The wheel assembly can include a first set of wheels to guide movement of the load handing device in a first direction and a second set of wheels to guide movement of the load handing device in a second direction. Each of the vehicle modules can include a container lifting means arranged to lift a container into the container receiving space and each of the vehicle modules can be moveable to adjust the spacing of the containers in the load handling device.

Abstract: A gripper for latching to a storage container is disclosed which includes: a gripper housing; a pair of gripper arms held in the gripper housing, wherein the gripper arms have cooperating shapes; and a movable rotatable actuator held in a channel between the pair of gripper arms for moving the gripper arms between closed and open positions. A load handling device for lifting and moving storage containers can include one or more grippers. A method of using a gripper, and a grid-based storage and retrieval system which can include at least one load handling device containing one or more grippers are also disclosed.

Abstract: An interferometric scattering microscope is adapted by performing spatial filtering of output light, which comprises both light scattered from a sample location and illuminating light reflected from the sample location, prior to detection of the output light. The spatial filtering passes the reflected illumination light but with a reduction in intensity that is greater within a predetermined numerical aperture than at larger numerical apertures. This enhances the imaging contrast for coherent illumination, particularly for objects that are weak scatterers.

Abstract: An apparatus, computer program and method is described comprising: separating neuron discharge patterns obtained from electromyography signals into one or more frequency band signals based on bandpass filter configuration parameters and converting one or more of said one or more frequency band signals into a one or more control signals, wherein said one or more control signals include one or more first control signals, wherein the or each first control signal is an independent augmented control signal.

Abstract: The present invention relates to containers which can be stacked one on top of another whilst still permitting easy access to the contents of any container within the stack without the need for de-stacking. The contents of the containers remain secured within the container.

Abstract: Apparatuses, methods, and systems are disclosed for uplink transmissions. One apparatus includes a processor that generates a preamble sequence for an uplink transmission. The preamble sequence of the apparatus includes indication information. The apparatus includes a transmitter that transmits the preamble sequence. The transmitter transmits uplink information based on the indication information.

Abstract: An object handling and retrieving system and method are described. A storage system is described suitable for storing multiple product lines in an automated warehouse environment. The storage system includes a plurality of load handling devices disposed above a frame and independently moveable to access different stacks. The load handling device can retrieve and transport a target container to a sequencing and temporary storage portion having a sorting frame for taking delivery of the target container and moving it to an output port of the sorting frame.

Abstract: A load handling device is disclosed for lifting and moving containers stacked in a storage system having a grid framework structure supporting a pathway arranged in a grid pattern above the stacks of containers. The load handling device includes a vehicle body housing a driving mechanism, the driving mechanism being powered by a rechargeable power source electrically coupled to an electrical charge point for electrically coupling with a charge head of a charge station; and a lifting device having a lifting drive assembly and a grabber device, wherein the lifting device includes the electrical charge point such that charging of the rechargeable power source occurs by the lifting device engaging with the charge head.

Abstract: The present disclosure is directed to radially-based magnetic resonance imaging. In any one or more embodiments, the present methods and systems provide that the angular increment between subsequent radial k-space spokes to be sampled to provide the imaging is performed for a predetermined or pre-defined restricted set of reconstruction window sizes (numbers of radial spokes per frame), or limited views, to maximize the uniformity of sampling within the restricted set of window sizes.