Abstract: A device configured to be implanted in a subject includes a sensing module, a therapeutic module, and a battery. The sensing module includes at least two of an accelerometer, an electrocardiogram (ECG) sensor, a photoplethysmogram (PPG) sensor, and a temperature sensor. The therapeutic module includes a drug reservoir and a reciprocating pump. The battery powers the sensing module and the therapeutic module. The sensing module is configured to detect a biological event in the subject and, upon detection of the biological event, send a signal to the therapeutic module. The therapeutic module is configured to receive the signal from the sensing module and, upon receiving the signal, administer a drug to the subject from the drug reservoir via the pump.

Abstract: Communication systems and methods in accordance with various embodiments of the invention utilize modulation on zeros. Carrier frequency offsets (CFO) can result in an unknown rotation of all zeros of a received signal's z-transform. Therefore, a binary MOCZ scheme (BMOCZ) can be utilized in which the modulated binary data is encoded using a cycling register code (e.g. CPC or ACPC), enabling receivers to determine cyclic shifts in the BMOCZ symbol remitting from a CFO. Receivers in accordance with several embodiments of the invention include decoders capable of decoding information bits from received discrete-time baseband signals by: estimating a timing offset for the received signal; determining a plurality of zeros of a z-transform of the received symbol; identifying zeros from the plurality of zeros that encode received bits by correcting fractional rotations resulting from the CFO; and decoding information bits based upon the received bits using a cycling register code.

Abstract: Disclosed herein are systems and techniques for seamless and scalable piezoresistive matrix-based intelligent textile development using digital flat-bed and circular knitting machines. Disclosed embodiments allow for combining and customizing functional conductive and polyester and spandex yarns, thus allowing for designing the aesthetics and architecting and engineering both the electrical and mechanical properties of the pressure sensing textile. In addition, by incorporating a melting fiber, disclosed embodiments allow for shaping and personalizing a three-dimensional piezoresistive fabric structure that can conform to the human body through thermoforming principles.

Abstract: The provided is a helmet for mental state regulation. The device includes: a helmet, an electroencephalogram (EEG) acquisition module set to the helmet, a signal analysis module, a vagus nerve stimulation module and a vagus nerve stimulation ear clip; the EEG acquisition module is used to acquire an EEG signal of a target user in real time, and preprocess the acquired EEG signal; the signal analysis module is used to extract features of the preprocessed EEG signal, and the extracted EEG features are input into a mental state assessment model to obtain a mental state value of the target user; the vagus nerve stimulation module is used to determine stimulation parameters of the vagus nerve stimulation ear clip according to the mental state value of the target user, and adjust the stimulation parameters adaptively and dynamically by obtaining the EEG features in real time.

Abstract: Lithium niobate (LiNbO3, LN) is a ferroelectric crystal of interest for integrated photonics owing to its large second-order optical nonlinearity and the ability to impart periodic poling via an external electric field. However, on-chip device performance based on thin-film lithium niobate (TFLN) is presently limited by propagation losses arising from surface roughness on the nano- and microscale. Atomic layer etching (ALE) can smooth these features and thereby increase photonic performance. In one embodiment disclosed herein, an isotropic ALE process for x-cut MgO-doped LN uses sequential exposures of H2 and SF6/Ar plasmas. We observed an etch rate of 1.59±0.02 nm/cycle with a synergy of 96.9%. ALE can be achieved with SF6/O2 or Cl2/BCl3 plasma exposures in place of the SF6/Ar plasma step with synergies of 99.5% and 91.5% respectively. The process decreased the sidewall surface roughness of TFLN waveguides etched by physical Ar+ milling by 30% without additional wet processing.

Abstract: The present invention relates to broadly neutralizing anti-HIV-1 antibodies and isolated antigens. Also disclosed are related methods and compositions.

Abstract: Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface. In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent. In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components. In some cases, the tissue interfacing component may comprise and/or be associated with the pharmaceutical agent.

Abstract: An example method of preparing spherical composite powders is provided. The method includes introducing one or more starting material powders into an agitation mill. The method includes introducing a process control agent into the agitation mill, the process control agent including at least two immiscible liquids. The method includes agitating and milling the one or more starting material powders and the process control agent with the agitation mill to produce substantially spherical composite powders.

Abstract: A method, including irradiating graphene oxide (GO) with a beam of light or radiation to form reduced graphene oxide (RGO) in a three-dimensional (3D) pattern, wherein the RGO is porous RGO with pores having sizes tuned by controlling the beam of light or radiation.

Abstract: Barocaloric heat transfer systems and related methods are generally described. In some embodiments, a heat transfer system may include a barocaloric material which may generate heat upon compression and may cool down upon decompression. The barocaloric material may be pressurized using high pressure and low pressure fluids, which may, in some embodiments, also transfer heat to/from the barocaloric material. The heat transfer system may also include a hot heat exchanger to dissipate heat from the heat transfer system to a first environment and a cold heat exchanger to absorb heat from a second environment, effectively cooling the second environment. In some embodiments, the barocaloric material may be in particulate form.

Abstract: In many embodiments of the invention, a space-based data center includes orbital server modules configured to be deployed in space, each module including a communication subsystem for module-to-module communications to form a data center, tiles arranged in a planar array, where each tile has a layered structure including solar cells forming a layer across a first surface, thermal radiator panels forming a layer across a second surface, electronic components distributed laterally in a layer between the layer of solar cells and the layer of thermal radiator panels, where each electronic component receives power locally from solar cells and rejects heat to the thermal radiator panel beneath it, where a first subset of tiles are compute tiles in which the electronic components include one or more computing processors and memory, and where a second subset of tiles are support tiles in which the electronics components include network switches and energy storage.

Abstract: A circuit comprising a first Fourier Transform block operable to perform a Fourier Transform and having a first input configured for receiving an I signal and a second input configured for receiving a Q signal; a first plurality of n of outputs for I channels and Q channels each comprising a different frequency bin output from the Fourier Transform; I and Q summing blocks comprising a set of connector lines connecting an ith one of I channels with an ith one of the Q channels; an inverse Fourier Transform block connected to the summing blocks and operable to perform an inverse Fourier Transform; a correlator for correlating the outputs of the inverse Fourier Transform; a Fourier Transform block for Fourier Transforming the correlator output; a comparator for comparing the correlation term to zero; and an error correction circuit for tuning the magnitude and phase of the I and Q channels using the comparator output as feedback.

Abstract: The exponential growth in deep learning models is challenging existing computing hardware. Optical neural networks (ONNs) accelerate machine learning tasks with potentially ultrahigh bandwidth and nearly no loss in data movement. Scaling up ONNs involves improving scalability, energy efficiency, compute density, and inline nonlinearity. However, realizing all these criteria remains an unsolved challenge. Here, we demonstrate a three-dimensional spatial time-multiplexed ONN architecture based on dense arrays of microscale vertical cavity surface emitting lasers (VCSELs). The VCSELs, coherently injection-locked to a leader laser, operate at gigahertz data rates with a 7T-phase-shift voltage on the 10-millivolt level. Optical nonlinearity is incorporated into the ONN with no added energy cost using coherent detection of optical interference between VCSELs.

Abstract: A cantilever may include a first dielectric layer that has a first intrinsic stress and a second dielectric layer overlying the first dielectric layer that has a second intrinsic stress that is different than the first intrinsic stress. The difference between the first and second intrinsic stresses may cause the cantilever to curve. A second dielectric layer can comprise a plurality of crossbars oriented at an angle relative to a length of the cantilever to reduce curvature in a width direction of the cantilever. The second dielectric layer can be patterned with a waveguide. The cantilever may be piezoelectrically actuated.

Abstract: Described herein are methods and uses thereof for in vivo evaluating functions of multiple genes in parallel by combining in utero genetic perturbation of progenitor cells and single-cell transcriptomic profiling of progeny cells in animals. These methods can be used, among other things, to reveal in vivo gene functions in a cell type-specific manner.

Abstract: In a real-time video transmission system for a cellular-connected unmanned aerial vehicle (UAV) based on an adaptive bitrate provided by the present disclosure, an on-board computer is loaded and configured on the UAV, such that the UAV can provide multiple video streams with different bitrates for retrieval. A client with a bitrate adaptation unit is set up, allowing the system to adjust the bitrate of the video stream according to network conditions in each time interval. Intranet penetration and port mapping are implemented on the cloud server, enabling the client to obtain, from the cloud server, the real-time video stream captured by the UAV. The present disclosure allows a remote user to watch, through a cellular network, the real-time video stream captured by the UAV.

Abstract: Methods, apparatuses, and systems related to the electrochemical separation of target gases from gas mixtures are provided. In some cases, a target gas such as carbon dioxide is captured and optionally released using an electrochemical cell (e.g., by bonding to an electroactive species in a reduced state). Some embodiments are particularly useful for selectively capturing the target gas while reacting with little to no oxygen gas that may be present in the gas mixture. Some such embodiments may be useful in applications involving separations from gas mixtures having relatively low concentrations of the target gas, such as direct air capture and ventilated air treatment.

Abstract: A system and method for enhancing communication between multiple parties includes a first user accessing a communication device; initiating a communication connection to a receiving communication device of a second user; and wherein at least one of the communication devices includes a list of enabled universal communication attributes of the user, utilizing one or more of the enabled communication attributes to complete the communication connection between the initiating and receiving communication devices. A user can select a desired communication attribute or multiple attributes which can be stored in the user's profile. The enabled attributes can be utilized by a network accessing the user's profile to complete the communication connection.

Abstract: A multiscale composite materials with few or no void defects are described. The composite materials include a network of porous materials. Methods and systems for the fabrication of the composite materials are generally described. According to certain embodiments, composite materials are fabricated without the use of an autoclave or low pressure environments.

Abstract: The present invention provides compositions and methods that allow lipid membranes to be imaged optically at nanoscale resolution via a lipid-optimized form of expansion microscopy, also referred to as membrane expansion microscopy (mExM). mExM, via a post-expansion antibody labeling protocol, enables protein-lipid relationships to be imaged in organelles such as mitochondria, the endoplasmic reticulum, the nuclear membrane, and the Golgi apparatus. mExM may be of use in a variety of biological contexts, including the study of cell-cell interactions, intracellular transport, and neural connectomics.