Abstract: Disclosed herein are a method, an apparatus, and a storage medium for image encoding/decoding. An intra-prediction mode for the target block is derived, and intra-prediction for the target block that uses the derived intra-prediction mode is performed. The intra-prediction mode for the target block is derived using an artificial neural network, and an MPM list for the target block is derived using information about the target block, pieces of information about blocks adjacent to the target block, and the artificial neural network. The artificial neural network outputs one or more available intra-prediction modes. Further, the artificial neural network outputs match probabilities for one or more candidate intra-prediction modes, and each of the match probabilities for the candidate intra-prediction modes indicates a probability that the corresponding candidate intra-prediction mode matches the intra-prediction mode for the target block.

Abstract: An error extraction method for foreground digital correction of a pipeline analog-to-digital converter including: acquiring a transmission curve of a pipeline analog-to-digital converter, and controlling an input signal to be within a sub-segment 0 of the transmission curve; during extraction of error information of an ith pipeline stage, setting a magnitude of the input signal according to Formula (I); locking the outputs of all previous-stage comparators in the ith pipeline stage of the pipeline analog-to-digital converter; and completing, according to original output code of the pipeline analog-to-digital converter, error extraction by means of adaptive iteration, stage-by-stage, sequentially from a last stage to a first stage of a pipeline.

Abstract: Provided are a surface-aminated mesoporous silica nanoparticle, a method of preparing the same, use of the nanoparticle for delivering a ribonucleoprotein, and use of the nanoparticle for the prevention or treatment of cancer. The surface-aminated mesoporous silica nanoparticle may be loaded with large RNPs such as Cas9-RNP, and thus may be applied to treatment of various diseases treatable by gene editing.

Abstract: The invention provides methods to monitor cell free nucleic acids.

Abstract: The present disclosure relates to compositions and methods for the diagnosis and treatment or prevention of EGLN1-dependent cancers. In particular, the instant disclosure provides for identification of a cancer as EGLN1-dependent, and selection and/or administration of an inhibitor of EGLN1 or VHL (Von Hippel-Lindau Tumor Suppressor) as a therapeutic agent for such a cancer and/or subject having or at risk of developing such a cancer.

Abstract: A nanoelectromechanical systems (NEMS) oscillator network and methods for its operation are disclosed. The NEMS oscillator network includes one or more network inputs configured to receive one or more input signals. The NEMS oscillator network also includes a plurality of NEMS oscillators coupled to the one or more network inputs. Each of the plurality of NEMS oscillators includes a NEMS resonator and produces a radio frequency (RF) output signal that oscillates at a particular frequency and a particular phase. The NEMS oscillator network further includes a plurality of connections that interconnect the plurality of NEMS oscillators. The NEMS oscillator network further includes one or more network outputs coupled to the plurality of NEMS oscillators and configured to output one or more output signals.

Abstract: Disclosed is a dTAG system comprising a small molecule degraders of FKBP12-tagged proteins via recruitment of Von Hippel-Lindau E3 ubiquitin ligase (VHL) E3 ubiquitin ligase and uses thereof.

Abstract: The present disclosure provides a differential clock cross point detection circuit and a detection method. The detection circuit includes: a first MOS transistor (M1), a second MOS transistor (M2) and a capacitor (C); a drain of the first MOS transistor (M1) is connected to a negative terminal (CLK?) of a differential clock, a gate of the first MOS transistor (M1) is connected to a positive terminal (CLK+) of the differential clock, and a source of the first MOS transistor (M1) is connected to a drain of the second MOS transistor (M2); a gate of the second MOS transistor (M2) is connected to the negative terminal (CLK?) of the differential clock, and a source of the second MOS transistor (M2) is connected to an output terminal through a node; one terminal of the capacitor (C) is connected to a node (A), and the other terminal of the capacitor (C) is grounded.

Abstract: A power electronic transformer structure includes: a support, a high-frequency transformer, a base, high-voltage side modules, and a low-voltage side module. The high-voltage side modules are respectively located at the front, top, and back of the support; the low-voltage side module is located at the bottom of the support; the high-frequency transformer is located at the middle of the support.

Abstract: Disclosed are a demand management control method and a demand management control apparatus for inducing dynamic participation of a consumer in an energy consumption load management program. The demand management control method refers to a promotion method for expanding an active participation of a consumer through a dynamic order of charging power of a charging load device with respect to a load having a consumption characteristic in an energy accumulation form in a distribution network management area in which an energy charging supply device is installed, and distributes and manages a demand within an energy supply goal of the consumer through a participation promotion. Also, the demand management control method provides changed cost information to the consumer using an incentive through a demand management contribution weight according to an energy demand and supply status and encourages or promotes the dynamic participation of the consumer.

Abstract: The invention relates to a system and method for CO2 capture. The system includes a fleet of CO2 producing assets comprising a fleet of assets having at least two individual assets that produce CO2 containing gas streams, and a set of modular CO2 capture units to capture the CO2 from the CO2 containing gas streams produced by the fleet of assets, wherein at least one of the individual assets is equipped with not less than two modular CO2 capture units, and at least one of the modular CO2 capture units is operated at more than one of the assets during the service life of the modular CO2 capture unit. The method for CO2 capture includes providing the fleet of assets and equipping them with a set of modular CO2 capture units. Advantage over current approaches is performance is optimized across a fleet of assets rather than at an individual site.

Abstract: The present disclosure provides, in some embodiments, in vitro blood brain barrier (iBBB) having functional properties of in vivo BBB as well as methods of identifying compounds capable of traversing the iBBB. Compounds capable of crossing the iBBB and therapeutic uses of such compounds are also described.

Abstract: The present disclosure provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof. The compounds of the present disclosure are inhibitors of kinases (e.g., a cyclin-dependent kinase (CDK) (e.g., CDK7)). The compounds may be selective for inhibiting the activity of a kinase (e.g., CDK7) over certain other kinases (e.g., CDK2, CDK9, CDK12). Also provided are pharmaceutical compositions, kits, methods of use, and uses that involve the compounds. The compounds may be useful in inhibiting the activity of a kinase, down-regulating the transcription of MYC or MCL-1, inhibiting the growth of a cell, inducing apoptosis of a cell, treating a disease, and/or preventing a disease (e.g., proliferative disease, cystic fibrosis).

Abstract: There are provided an apparatus, method, system, and recording medium for performing selective encoding/decoding on feature information. An encoding apparatus generates residual feature information. The encoding apparatus transmits the residual feature information to a decoding apparatus through a residual feature map bitstream. The residual feature information is the difference between feature information extracted from an original image and feature information extracted from a reconstructed image. Feature information of the reconstructed image is generated using the reconstructed image. Reconstructed feature information is generated using the feature information of the reconstructed image and reconstructed residual feature information.

Abstract: Disclosed is a preparation method of a renewable epoxy asphalt material and a regeneration process. The preparation method comprises: I Vanillin and 4-aminophenol are reacted in water with stirring to obtain VAN-AP; II. VAN-AP is mixed with epichlorohydrin, to which tetrabutylammonium bromide is added and heated at 80 to 90° C. for reaction; sodium hydroxide solution is then added dropwise for reaction; the mixture is concentrated to obtain GE-VAN-AP; III. Preheated asphalt is mixed with a polyetheramine curing agent and a polyetheramine accelerator to form component A; GE-VAN-AP is melted as component B; the component A is evenly mixed with the component B to obtain a renewable epoxy asphalt material. During the regeneration, the resin phase structure in the epoxy asphalt is gradually depolymerized, whereby asphalt regenerant is used to restore the properties of the aged asphalt phase and reshape the resin phase structure to complete the regeneration.

Abstract: The disclosed embodiments relate to a dismantling device configured for a frame of a PV module. The dismantling device includes a connection portion, a first holding portion, and a second holding portion. The first holding portion is connected to the connection portion and configured to press against one of an inner wall and outer wall of the frame. The second holding portion is slidably disposed on the connection portion and movably closer to or away from the first holding portion along a sliding direction. The second holding portion is configured to press against the other one of the inner wall and the outer wall so as to clamp the frame with the first holding portion and to distort the frame.

Abstract: Disclosed herein are an apparatus and method for generating a proxy for a Dockerized AI library. The method may include generating a proxy server and a proxy client for relaying access to an AI library based on an interface predefined for the access to the AI library generated as a Docker image according to an embodiment, generating a Dockerfile in order to generate a new Docker image configured to run the AI library in the form of a server using the generated proxy server, and generating the new Docker image based on the Dockerfile.

Abstract: Recombinant adenovirus genomes that include a heterologous open reading frame (ORF) and a self-cleaving peptide coding sequence are described. The recombinant adenovirus genomes and recombinant adenoviruses produced by the disclosed genomes can be used, for example, in high-throughput assays to measure virus replication kinetics. Methods for measuring replication kinetics of a recombinant adenovirus are also described.

Abstract: A hydrate kinetic inhibitor, which is prepared by a polymerization of mercaptoethanol and N-vinylcaprolactam, is hydroxyl terminated poly(N-vinylcaprolactam) having a structure of formula (I) below, wherein n=10 to 1000. The inhibitor is a novel hydrate kinetic inhibitor, which has low effective concentration and high cloud point, and is effective when the degree of supercooling is relatively high.

Abstract: The present disclosure relates to compositions, methods, and kits for increasing the viability of bacteria that have been subjected to freeze-drying/lyophilization. In particular, the disclosure relates to compositions and methods for increasing the viability of living medicines (e.g.