Abstract: In accordance with one or more embodiments of the present disclosure, a method of starting a fuel reformer including a heating element and a subsequent autothermal reformer includes contacting a first fluid comprising oxygen with the heating element, passing the first fluid into the autothermal reformer to preheat a reformer catalyst within the autothermal reformer to a first temperature, reducing flow of the first fluid into the autothermal reformer, introducing a fuel into the autothermal reformer subsequent to preheating the reformer catalyst to initiate a partial oxidation reaction and generating additional heat, increasing flow of the fuel and first fluid to initiate autothermal reforming, and controlling the temperature of the reformer catalyst by supplying a cooling fluid, the first fluid, and the fuel and adjusting flow of each.

Abstract: Isoxazoles of formula (A) or (B) are inhibitors of HSP90 activity, and useful for treatment of, for example cancers: wherein R1, is a group of formula (IA): —Ar1-(Alk1)p-(Z)r-(Alk2)s-Q, wherein in any compatible combination Ar1 is an optionally substituted aryl or heteroaryl radical, Alk1 and Alk2 are optionally substituted divalent C1-C6 alkylene or C2-C6 alkenylene radicals, p, r and s are independently 0 or 1, Z is -0-, —S—, —(C?O)—, —(C?S)—, —SO.sub.

Abstract: The present invention relates to a wireless communication terminal and a wireless communication method for efficiently scheduling uplink multi-user transmission. To this end, provided are a base wireless communication terminal, including: a transceiver configured to transmit and receive a wireless signal; and a processor configured to control an operation of the transceiver, wherein the processor selects an access category for transmitting a trigger frame which solicits an uplink multi-user transmission, performs a backoff procedure for transmitting the trigger frame based on the selected access category, and transmits the trigger frame when a backoff counter of the backoff procedure expires and a wireless communication method using the same.

Abstract: Apparatus, system and method for medical analysis of a seated individual, includes determining the aortic valve opening; the PTT; and calculating the PWV. Determining the aortic valve opening includes collecting BCG data while sitting on a seat and determining the timing of the aortic valve opening, taking into account posture. Measuring the aortic pulse wave transit time includes collecting BCG data while sitting on a seat capable of measuring changes in apparent weight; determining the timing of the aortic valve opening; detecting the arrival of the pulse wave at the end point; and measuring the relative timings of the two events. Calculating the PWV includes determining a length of the arterial segment through which a pulse wave is to be measured between a start point and an end point; and dividing the determined length of the arterial segment by the PTT.

Abstract: The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections.

Abstract: Methods, compositions, and kits are provided for quantification of genome editing.

Abstract: The invention provides for use of CRISPR-Cas systems to sort barcoded cells or molecules. Cells or nucleic acid molecules may be sorted from a heterogenous population by targeting a barcode of interest specific for a cell or cell progeny or nucleic acid molecule of interest.

Abstract: Disclosed is an apparatus for centralized charging of electronic products, including a base, where charging grooves, charging racks, and a charging stand are provided on the top surface of the base in sequence from front to back; a charging head A is provided in the charging groove; a connecting piece A matching a plug-in type charging head is provided at the lower part of the charging rack; the base is further provided with connecting pieces B matching the plug-in type charging heads; the connecting pieces B are located at one side of the charging stand; and the charging head A, the connecting piece A, and the connecting piece B are electrically connected to an output end of a power adapter provided in the base, respectively.

Abstract: The present invention relates to a method for producing dextran polymer-based amplified nucleic acid aptamer nanoconstructs which efficiently and selectively capture a specific target molecule, the method comprising linking a short nucleic acid sequence or a complementary sequence for formation of nanoconstructs and a nucleic acid aptamer sequence for capture of the specific target molecule to a dextran polymer by a chemical reaction, mixing the resulting polymer/nucleic acid substances with each other to form nanostructures, subjecting the nanostructures to rolling circle amplification, thereby forming a nucleic acid aptamer having a repeated structure. The dextran polymer-based amplified nucleic acid aptamer nanoconstructs have the effect of efficiently and selectively capturing a specific target molecule.

Abstract: An ophthalmic lens for treating myopia comprising: a base lens with a front surface, a back surface, and a first power profile selected to correct or substantially correct for a distance refractive error of the eye; one or more myopia control elements on at least one of the front and back surfaces of the lens; a first viewing region having a dimension selected based, at least in part, on a concentration of a pharmaceutical agent for use in conjunction with an ophthalmic lens, the first viewing region being configured to minimize, reduce and/or eliminate vision disturbances for distance vision; and a second viewing region comprising a power profile that is relatively more positive compared to the first viewing region; wherein at least one of the size of the second viewing region and the relatively more positive power of the second viewing region is selected based, at least in part, on the concentration of the pharmaceutical agent.

Abstract: Provided is a method and apparatus for discontinuously transmitting/receiving packets for low-power consumption of a terminal in a cellular system for packet transmission. The present research provides a method and apparatus that can perform a low-power consuming operation when a terminal is in active state in a cellular system. The method for discontinuously transmitting/receiving packet data to reduce power consumption of a terminal in a cellular system, including the steps of: a) establishing discontinuous reception/transmission (DRX/DTX) parameters including discontinuous DRX/DTX cycle information for terminals operating in a transmission suspension mode, which is a sub-state of an active state; and b) performing DRX/DTX based on the DRX/DTX parameters in the terminals operating in the transmission suspension mode.

Abstract: A method and system for preprocessing microscopic images. A method includes identifying a plurality of microglial cells shown in microglial cell channel images, wherein identifying the plurality of microglial cells further comprises quantizing the microglial cell channel microscopic images and filtering a plurality of objects in the quantized microglial cell channel microscopic images; identifying a soma and at least one projection for each of the plurality of microglial cells, wherein identifying the soma and the at least one projection for each microglial cell further includes iteratively removing pixels on the microglial cell as shown in one of the microglial cell channel images, wherein each soma and each projection has a respective size; and determining an activation state of each microglial cell based on the size of the soma and a total size of the at least one projection identified for the microglial cell.

Abstract: A chip package structure including first and second insulating layers, first and second circuit structures, a chip on the first circuit structure, an encapsulant, a conductive through via, and first and second heat dissipation layers is provided. The first circuit structure is disposed at the first surface of the first insulating layer. The bottom electrode of the chip is electrically connected to the first circuit structure. The second circuit structure is disposed on the chip and electrically connected to the top electrode of the chip. The encapsulant encapsulates the first and second circuit structures and the chip. The conductive through via is disposed in the encapsulant and connects the first and second circuit structures. The second insulating layer is disposed on the second circuit structure. The first heat dissipation layer is disposed on the first insulating layer. The second heat dissipation layer is disposed on the second insulating layer.

Abstract: Methods to build multi-functional scattering structures while respecting tight requirements imposed by manufacturing processes are described. The described methods and devices are based on etching away wire networks embedded in 3D structures to form voids in order to perform a target function. Optimization algorithms for designing binarized devices that meet manufacturing requirements are also disclosed.

Abstract: A method for soil moisture retrieval using multi-channel collaboration algorithm and passive microwave radiometry including: establishing mathematical relationship formula between brightness temperatures at any two channels according to microwave radiative transfer equation; collecting actual brightness temperatures of core channel and collaborative channels; selecting parameters to be retrieved including soil moisture value; giving a series of estimated values of parameters to be retrieved, calculating a series of predicted brightness temperatures of collaborative channels according to actual brightness temperature of core channel, microwave radiative transfer equation and mathematical relationship formula, comparing predicted brightness temperatures with actual brightness temperature, and determining soil moisture value.

Abstract: A method for providing maximum traffic flow throughput and controlling vehicular pollution concentration is provided. The method includes (i) processing a source location and a destination location obtained from a user device associated with a user to determine at least one possible route to reach the destination location from the source location, (ii) determining at least one maximum flow route that includes at least one edge with an edge capacity from the at least one possible route, (iii) determining maximum traffic flow capacity for the at least one maximum flow route, (iv) determining active traffic flow routes by comparing continuously if shared or common edges of a plurality of route solutions is less than or equal to a pre-defined limit and (v) partitioning the maximum traffic flow capacity for the active traffic flow routes and permuting each partition of the maximum traffic flow capacity for the active traffic flow routes.

Abstract: In an apparatus for evaluating reliability of a nuclear power plant operator, an expected task finishing time for each task of the operator is calculated based on input data for reliability evaluation of the operator to determine a task completion time for each task of the operator based on the calculated expected task finishing time and the input data. An initial time for the tasks is determined based on the input data and the task completion time for a current task. A total execution time of the operator is calculated based on the determined task completion time and initial time. An available time allowed for the operator to complete the tasks is calculated based on a predetermined allowed time and the determined initial time. A task failure probability is obtained from the difference between the calculated total execution time and the calculated available time based on probability distribution information.

Abstract: A device for searching a biomarker to be used for determining whether or not a first treatment has an effect on a disease, the biomarker search device includes: a first storage; a second storage storing; a third storage; a fourth storage; a signature molecular information detector; a regression analyzer; a network generator; and a biomarker determinator.

Abstract: A package structure is provided. The package structure includes a substrate. The package structure also includes a hybrid pad disposed on the substrate. The hybrid pad includes a metal layer and a buffer layer connected to the metal layer. The Young's modulus of the buffer layer is less than the Young's modulus of the metal layer. The package structure further includes an electrically connecting structure disposed on the hybrid pad. The package structure includes a chip layer electrically connected to the electrically connecting structure. The package structure also includes a bonding pad disposed between the electrically connecting structure and the chip layer.

Abstract: An object is to provide a technology for enabling prevention of deterioration of characteristics of an oxide semiconductor device. The oxide semiconductor device includes an n-type gallium oxide epitaxial layer, a p-type oxide semiconductor layer, and an oxide layer. The p-type oxide semiconductor layer is disposed above the n-type gallium oxide epitaxial layer, contains an element different from gallium as a main component, and has p-type conductivity. The oxide layer is disposed between the n-type gallium oxide epitaxial layer and the p-type oxide semiconductor layer, and is made of a material different from gallium oxide and different at least partly from a material of the p-type oxide semiconductor layer.