Abstract: Dual variable domain (DVD) immunoconjugates and uses thereof are provided. Aspects of the subject immunoconjugates include a DVD immunoglobulin molecule having a first and a second variable domain, and a cargo moiety (e.g., a drug moiety) that is covalently conjugated to the second variable domain via a linker. Methods of making and using the subject immunoconjugates in the prevention and/or treatment of cancer and other diseases are also provided.

Abstract: Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.

Abstract: Testing for software applications can be implemented according to some aspects described herein. For example, a system can receive override data, including a location of a logical statement in source code and an override command, that is associated with a software application. The system can generate debugging data based on the override data, the debugging data including a breakpoint associated with the location and a debugger command corresponding to the override command. The system can then provide the debugging data as input to debugging software, the debugging software being configured to monitor execution of the software application during a software test. The debugging software can determine that the breakpoint has been reached and responsively execute the debugger command for testing a target portion of source code for the software application.

Abstract: An optical processor is presented for applying optical processing to a light field passing through a predetermined imaging lens unit. The optical processor comprises a pattern in the form of spaced apart regions of different optical properties. The pattern is configured to define a phase coder, and a dispersion profile coder. The phase coder affects profiles of Through Focus Modulation Transfer Function (TFMTF) for different wavelength components of the light field in accordance with a predetermined profile of an extended depth of focusing to be obtained by the imaging lens unit. The dispersion profile coder is configured in accordance with the imaging lens unit and the predetermined profile of the extended depth of focusing to provide a predetermined overlapping between said TFMTF profiles within said predetermined profile of the extended depth of focusing.

Abstract: A method for regenerating an amine-based, acid gas absorbent using a mixed catalyst containing silver oxide and silver carbonate includes the steps of absorbing an acid gas into an acid gas absorbent having an amine group to obtain an acid gas-absorbed absorbent; and regenerating the amine-based, acid gas absorbent by adding a catalyst mixture containing silver oxide and silver carbonate to the acid gas-absorbed absorbent and by removing the acid gas at a temperature ranging from 40° C. to 86° C. When the amine-based acid gas absorbent is an acid gas absorbent solution and when the acid gas that is absorbed into the acid gas absorbent solution is carbon dioxide, the catalyst mixture efficiently promotes decomposition of carbon dioxide-bound carbamate in the acid gas absorbent solution that absorbs the carbon dioxide through a novel catalytic reaction pathway.

Abstract: A reactivation composition for activating or re-activating expression of a silenced X chromosome gene in a cell includes a non-cytotoxic histone deacetylase (HDAC) inhibitor. The reactivation composition includes the non-cytotoxic HDAC inhibitor and may further include a DNA methylation inhibitor. A method of activating or re-activating expression of a silenced X chromosome gene in a cell includes administering a reactivation composition including a non-cytotoxic HDAC inhibitor. The method of activating or re-activating expression of a silenced X chromosome gene may further includes administering a reactivation composition that includes a non-cytotoxic HDAC inhibitor and an inhibitor of DNA methylation.

Abstract: Apparatus and methods relating to programmable superconducting cells are described. A programmable superconducting cell can be formed from a superconducting current loop having at least two terminals connected to the loop. The current loop and terminals can be formed from a single layer of superconducting material. The programmable superconducting cell can be incorporated into a crossbar architecture to form a high-speed vector-matrix multiplying processor for deep neural network computations.

Abstract: The invention relates to a terahertz full polarization state detection spectrometer, which comprises a terahertz wave generator, a polarizer, a polarization splitter, a horizontal terahertz detector and a vertical terahertz detector. The terahertz wave generator generates a terahertz wave and the polarizer optimizes the terahertz wave for purity. The sample to be detected modulates the terahertz wave after purity optimization to obtain the terahertz modulated wave. The terahertz modulated wave is decomposed by the polarization splitter into a horizontal terahertz wave and a vertical terahertz wave whose polarization states are perpendicular to each other. The two terahertz waves are detected by two corresponding terahertz detectors respectively. According to the detected result, the characteristic of the sample is analyzed.

Abstract: A wireless sensor platform design and a single walled carbon nanotube/ionic liquid-based chemidosimeter system can incorporated into a highly sensitive and selective chemical hazard badge that can dosimetrically detect an analyte down to a sub parts-per-million concentration.

Abstract: Spectrally-efficient digital logic (SEDL) techniques implement spectrally-efficient pulses (e.g., Gaussian-shaped pulses) in lieu of conventional square waveforms to improve electromagnetic, radio frequency, and other unwanted emissions. The SEDL techniques can be used for analog-to-digital converters (ADC) and digital-to-analog converters (DAC). An ADC circuit comprises a plurality of comparators configured to receive an analog input signal and compare the analog input signal to a predetermined reference signal, an encoder, and a spectrally-efficient circuit. A DAC circuit includes an integrator circuit, a clocked comparator circuit, a pulse generator, and a combiner circuit. The clocked comparator circuit receives the logic state of each SEDL pulse. The pulse generator receives the logic state and generates a scaled SEDL pulse for each input SEDL pulse. A combiner circuit combines the outputs from the pulse generator and determines analog value corresponding to the input values.

Abstract: An interrupt control device between clock domains is provided. An interrupt sharing logic is configured to receive one or more original interrupt signals and generate a combined interrupt signal. An interrupt processing logic is configured to output a processed interrupt signal to a processor according to the combined interrupt signal, so that the processor executes an interrupt service routine. When the interrupt service routine is executed, the processed interrupt signal changes to be disabled; before the interrupt service routine is completed, the processor outputs an interrupt clear signal to change the respective interrupt signal to be negated. After the interrupt processing logic detects that interrupt signal has been cleared successfully, the interrupt processing logic will generate the processed interrupt signal according to the combined interrupt signal again.

Abstract: The present invention relates to a wireless communication terminal and a wireless communication method for efficiently scheduling uplink multi-user transmission. To this end, provided are a base wireless communication terminal, including: a transceiver configured to transmit and receive a wireless signal; and a processor configured to control an operation of the transceiver, wherein the processor selects an access category for transmitting a trigger frame which solicits an uplink multi-user transmission, performs a backoff procedure for transmitting the trigger frame based on the selected access category, and transmits the trigger frame when a backoff counter of the backoff procedure expires and a wireless communication method using the same.

Abstract: The techniques described herein relate to methods and apparatus for a resistive switching device. The resistive switching device includes a first electrode formed in a substrate. The resistive switching device also includes a plurality of layers formed above the first electrode, including a plurality of oxide layers, wherein one or more of the plurality of oxide layers comprise doped oxide layers, and one or more conductive spacers, wherein each pair of oxide layers of the plurality of oxide layers are separated by a conductive spacer of the one or more conductive spacers. The resistive switching device also includes a second electrode formed above the plurality of layers, such that the first electrode, the plurality of layers, and the second electrode are in series.

Abstract: A method and system for heat recovery and/or power plant cooling, incorporating an ejector configured to transfer vapor from a generator to a condenser. The ejector includes a converging-diverging nozzle to create a low pressure zone that entrains a fluid. The ejector is within a cooling fluid cycle line in heat exchange combination with an exhaust flue gas. Two fluid flows of the fluid cycle line are mixed via the ejector into a combined fluid, wherein the ejector adjusts a temperature and/or pressure of the combined fluid. Condensing the combined fluid provides a cooling medium.

Abstract: The present invention provides pharmaceutical compounds for the treatment of high-grade superficial bladder cancer in patent in need thereof. Further described are compositions of azolium salts for use in such treatment.

Abstract: A method for efficiently preparing ferrate based on nascent state interfacial activity. The method is as follows: (a) preparing nascent iron solution; (b) adding an oxidizing agent to the iron solution of step (a); (c) adding alkali solution or alkali particles to the mixed solution of step (b), mixing by stirring, and carrying out solid-liquid separation; (d) adding a stabilizing agent to the liquid separated out in step (c), and thus obtaining ferrate solution. The yield is 78-98%. The prepared ferrate solution is stable and can be stored for 3-15 days.

Abstract: The present invention provides a pharmaceutical composition for inhibiting the metastasis of cancer, comprising, as an active ingredient, an antibody that specifically binds to an epidermal growth factor receptor, and a method for inhibiting the metastasis of cancer using the composition. The composition or the method is effective in inhibiting the invasion of various gastric cancer cell lines induced by EGFR ligands. Therefore, the pharmaceutical composition can be usefully used for inhibiting the metastasis of cancer.

Abstract: A method and apparatus for optimizing average bit error probability via a deep multi-armed bandit in an orthogonal-frequency division multiplexing and index modulation system for low power communication are proposed. The method proposed in the present invention comprises: detecting BPSK symbols and subcarriers among all subcarriers; defining a combination of selected subcarriers as a subcarrier selection pattern; selecting the subcarrier selection pattern through learning to minimize the average bit error probability for all combinations of selected subcarriers; and updating a learning parameter of the subcarrier selection pattern selected through learning.

Abstract: The image decoding method according to the present invention comprises the steps of: determining the availability of a block adjacent to a current block; configuring a merge candidate list for the current block on the basis of the result of the determined availability; and performing motion compensation for the current block on the basis of the merge candidate list, wherein the step of determining availability comprises the steps of inducing block availability information on the adjacent block and inducing the availability of motion information on the adjacent block, and the step of determining the availability of the adjacent block is such that when there is more than one adjacent block, the availability of adjacent blocks can be determined in accordance with a predetermined order restriction.

Abstract: A medium for culturing Balantidium ctenopharyngodoni in vitro, method for preparing the medium and method for culture in vitro are provided, which belongs to technical field of in vitro culture of intestinal protozoa. The formulation of the culture medium includes: 100 ml of Ringer's solution, 0.5 g of yeast extract, 1.0 g of proteose peptone, 3-6 ml of fetal bovine serum, 6-10 ml of horse serum, 300-500 ?l of Bacillus licheniformis suspension, 200-300 mg of aseptic starch. Culture steps include: inoculating collected Balantidium ctenopharyngodoni into a prepared medium, filling with nitrogen and sealing, culturing at 15° C. for 48-72 hours, then transferring to another fresh medium, cycling back and forth, proliferating the Balantidium ctenopharyngodoni continuously. Balantidium ctenopharyngodoni are capable of achieving cell division and proliferation in the culture medium, and lays foundation for the physiological and experimental ecology research of the Balantidium ctenopharyngodoni.