Abstract: The present application relates to compounds of Formula I or pharmaceutically acceptable salts, solvates and/or prodrugs thereof, to compositions comprising these compounds or pharmaceutically acceptable salts, solvates and/or prodrugs thereof, and various uses in the treatment of diseases, disorders or conditions that are treatable by inhibiting interactions with BCL6 BTB and/or by degrading BCL6, such as cancer.
Type:
Grant
Filed:
December 20, 2018
Date of Patent:
December 7, 2021
Assignee:
ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR)
Abstract: A multistatic array topology and image reconstruction process for fast 3D near field microwave imaging are presented. Together, the techniques allow for hardware efficient realization of an electrically large aperture and video-rate image reconstruction. The array topology samples the scene on a regular grid of phase centers, using a tiling of multistatic arrays. Following a multistatic-to-monostatic correction, the sampled data can then be processed with the well-known and highly efficient monostatic Fast Fourier Transform (FFT) imaging algorithm. In this work, the approach is described and validated experimentally with the formation of high quality microwave images. The scheme is more than two orders of magnitude more computationally efficient than the backprojection method. In fact, it is so efficient that a cluster of four commercial off-the-shelf (COTS) graphical processing units (GPUs) can render a 3D image of a human-sized scene in 0.048-0.101 seconds.
Type:
Grant
Filed:
June 6, 2019
Date of Patent:
December 7, 2021
Assignee:
Massachusetts Institute of Technology
Inventors:
William F. Moulder, James D. Krieger, Denise T. Maurais-Galejs, Huy T. Nguyen, Jeffrey S. Herd
Abstract: The present invention relates to a system for providing multimedia service, comprising a network device which provides multimedia services using a wireless network, and a terminal which receives the multimedia services from the network device. The network device may receive feedback on the multimedia service receiving state from the terminal that receives the multimedia services, and control the multimedia services based on the received feedback.
Type:
Grant
Filed:
December 5, 2012
Date of Patent:
December 7, 2021
Assignee:
Electronics and Telecommunications Research Institute
Abstract: A printing head module, system and method for printing laser light sources. The printing head module comprises one or more printing heads used for printing a plurality of laser light sources on a substrate successively or once for all; ink used for printing comprises a luminescent dye and a host material, as well as a solvent. The system comprises a printing head module and an ink cartridge; the printing head module is used for inkjet printing the laser light sources on the substrate; the ink cartridge is used for storing ink. By means of the technical solution, industrial manufacturing of the laser light sources is achieved, and speckles caused by laser coherence are eliminated.
Type:
Grant
Filed:
May 4, 2018
Date of Patent:
December 7, 2021
Assignee:
INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES
Inventors:
Yongsheng Zhao, Jiannian Yao, Jinyang Zhao, Yongli Yan
Abstract: Systems, methods, and computer-readable media for protecting cryptographic keys are provided. Each cryptographic key is divided into multiple shares for storage at remote locations and for storage on a local device.
Type:
Grant
Filed:
March 9, 2021
Date of Patent:
December 7, 2021
Assignee:
TECHNOLOGY INNOVATION INSTITUTE
Inventors:
Septimiu F. Mare, Najwa Aaraj, Marcos Manzano, Alvaro Garcia
Abstract: Metaphosphate compounds can directly phosphorylate other compounds to provide easy synthetic access to phosphorylated compounds, including cyclic phosphate compounds.
Abstract: A terrain modeling method that fuses geometric characteristics and mechanical characteristics, and a terrain modeling system are provided in the present invention. The method includes steps of: obtaining color images and depth images of the detected region, performing a terrain semantic segmentation on the color images, and fusing ground semantic information obtained by the semantic segmentation and depth information contained in the depth images at the same time to generate the point clouds; mapping the point clouds to a raster map in a map coordinate system to generate corresponding rasters, and updating the elevation values to the corresponding rasters; and calculating the input images in terms of terra-mechanical characteristics, and updating calculation results to the corresponding rasters to generate a terrain model.
Type:
Grant
Filed:
March 23, 2020
Date of Patent:
December 7, 2021
Assignee:
HARBIN INSTITUTE OF TECHNOLOGY
Inventors:
Liang Ding, Zongquan Deng, Ruyi Zhou, Haibo Gao, Wenhao Feng, Peng Xu, Nan Li, Zhen Liu
Abstract: A millimeter wave image based human body foreign object detection method, comprising: acquiring a millimeter wave gray scale image of a human body; according to a pre-determined foreign object imaging characteristic, extracting from the millimeter wave gray scale image a foreign object area image; according to a pre-determined foreign object image recognition algorithm, performing calculations on the foreign object area image, and acquiring a foreign object image from the foreign object area image; displaying the foreign object image as a foreign object detection result. Also provided is a millimeter wave image based human body foreign object detection system.
Type:
Grant
Filed:
August 4, 2017
Date of Patent:
December 7, 2021
Assignees:
CHINA COMMUNICATION TECHNOLOGY CO., LTD., Shenzhen Institute of Terahertz Technology and Innovation
Abstract: The present disclosure is directed to systems and methods for producing a metal-containing powder useful for additive manufacturing. The metal-containing powder includes a plurality of metal-containing platelets having a defined physical geometry and a defined aspect ratio. The metal platelets may be produced by depositing a metal layer on a substrate that includes one or more recessed or raised surface features. The one or more recessed or raised surface features create a fracture pattern in a metal layer deposited across at least a portion of the one or more surface features. By separating the metal layer from the substrate and fracturing the metal layer along the fracture pattern, a plurality of metal platelets are produced. In some embodiments, a release agent may be disposed between the metal layer and the substrate to facilitate the separation of the metal layer from the substrate.
Type:
Grant
Filed:
June 20, 2019
Date of Patent:
December 7, 2021
Assignee:
SOUTHWEST RESEARCH INSTITUTE
Inventors:
Vasiliki Z. Poenitzsch, Randy L. McKnight, Carl F. Popelar, Michael A. Miller, John H. Macha, Kent E. Coulter
Abstract: Disclosed are a system for and a method of manufacturing a three-dimensional (3D) structure. The method may include injecting a fluid with a first pressure toward a surface of a first output layer to form a softening layer in the first output layer, injecting the fluid with a second pressure toward the softening layer to form an uneven structure in the softening layer, the second pressure being higher than the first pressure, and forming a second output layer on the softening layer with the uneven structure.
Type:
Grant
Filed:
February 12, 2020
Date of Patent:
December 7, 2021
Assignee:
Electronics and Telecommunications Research Institute
Inventors:
Ji-Young Oh, Yong Suk Yang, Kyung Hyun Kim, Kyu Sung Lee
Abstract: Provided are an anchor pin for placing shotcrete and fixing a textile grid and a method of constructing textile grid reinforced shotcrete using the same, wherein the anchor pin allows a textile grid reinforcement to be precisely disposed at a required position and, when shotcrete is placed, prevents a textile grid reinforcement from moving due to a driving pressure for precise construction so as to increase durability and safety of the concrete structure, allows primary and secondary shotcrete to be constructed while placing thicknesses thereof are visually checked so as to increase precision of construction, and allows the textile grid reinforcement to be disposed and fixed to accurately correspond to a shape of the concrete structure even when a lower portion of a slab, a wall, and a structure with a curved surface, such as a lining of a tunnel, are built.
Type:
Grant
Filed:
November 27, 2019
Date of Patent:
December 7, 2021
Assignee:
KOREA INSTITUTE OF CIVIL ENGINEERING AND BUILDING
TECHNOLOGY
Inventors:
Hyeong Yeol Kim, Kyung Taek Koh, Gum Sung Ryu, Gi Hong An, Dong Woo Seo, Seung Seop Jin
Abstract: Provided herein are, inter alia, methods and compositions to detect, monitor and treat cancer, wherein the cancer includes amplified extrachromosomal oncogenes. The methods are useful for personalized treatment and exploit differential expression of amplified extrachromosomal oncogenes in cancer cells versus healthy cells.
Type:
Grant
Filed:
May 24, 2018
Date of Patent:
December 7, 2021
Assignees:
The Regents of the University of California, Ludwig Institute for Cancer Research Ltd
Inventors:
Paul Mischel, Prashant Mali, Vineet Bafna, Kristen Turner, Viraj Deshpande, Doruk Beyter
Abstract: Embodiments of techniques for analyzing one or more genomic regions of a genome of an organism. Data about a genomic region may be analyzed to determine an information content of the genomic region, which may indicate an amount of information provided by the genomic region. The data about the genomic region may be or include data identifying a chromatin state for the genomic region. A chromatin state may be one of a set of chromatin states that each define a different set of one or more chromatin characteristics. Chromatin characteristics may be structural and/or functional features of genomic regions. A chromatin state of a genomic region may be determined from, and describe, the genomic region such that when a genomic region has a set of one or more chromatin characteristics, a chromatin state associated with that combination of one or more chromatin characteristics is identified for the genomic region.
Abstract: The present invention relates to the field of high polymer material manufacturing, and discloses an air-isolated continuous feeding system for synthesizing polylactic acid from lactide and a feeding method thereof. The continuous feeding system comprises a raw material bag/box and a raw material collector for collecting and outputting lactide, the raw material bag/box is connected with a shielding gas input pipeline, a discharge pipe is movably inserted into the raw material bag/box, a cyclone separator is connected downstream of the discharge pipe, and a solid substance outlet of the cyclone separator is connected with the raw material collector. According to the invention, deterioration of the lactide raw material incurred by moisture absorption and oxidation is avoided, and the reaction conversion ratio and final product purity are improved. The continuous feeding system is easy to operate, can save manpower and material resources, and is applicable to industrial application.
Type:
Grant
Filed:
December 29, 2020
Date of Patent:
December 7, 2021
Assignees:
Nutrition & Health Research Institute, COFCO Corporation, COFCO (jilin) Bio-Chemical Technology CO., Ltd, Jilin COFCO Biomaterial Co., Ltd, COFCO Biotechnology Co., Ltd.
Inventors:
Yi Tong, Yi Li, Fang Tian, Bo Chen, Tai An, Lida Wu
Abstract: Provided is a wireless communication terminal that communicates wirelessly. The terminal includes: a transceiver; and a processor. The processor is configured to receive a Downlink Multi-User (DL MU) PPDU including information for an Uplink Multi-User (UL MU) transmission from a base wireless communication terminal by using the transceiver, and transmit the UL MU PPDU to the base wireless communication terminal based on the information for UL MU transmission.
Type:
Grant
Filed:
April 16, 2020
Date of Patent:
December 7, 2021
Assignees:
WILUS INSTITUTE OF STANDARDS AND TECHNOLOGY INC., SK TELECOM CO., LTD.
Abstract: Disclosed is a semantic sentiment analysis method fusing in-depth features and time sequence models, including: converting a text into a uniformly formatted matrix of word vectors; extracting local semantic emotional text features and contextual semantic emotional text features from the matrix of word vectors; weighting the local semantic emotional text features and the contextual semantic emotional text features by using an attention mechanism to generate fused semantic emotional text features; connecting the local semantic emotional text features, the contextual semantic emotional text features and the fused semantic emotional text features to generate global semantic emotional text features; and performing final text emotional semantic analysis and recognition by using a softmax classifier and taking the global semantic emotional text features as input.
Type:
Grant
Filed:
September 1, 2021
Date of Patent:
December 7, 2021
Assignee:
INSTITUTE OF AUTOMATION, CHINESE ACADEMY OF SCIENCES
Inventors:
Jianhua Tao, Ke Xu, Bin Liu, Yongwei Li
Abstract: The present disclosure provides a solar heat absorber including: an inlet through which a heat collecting medium enters the solar heat absorber; a passage member configured to be fluidly connected with the inlet such that the heat collecting medium enters the passage member through the inlet; and a collection member configured to be fluidly connected with the passage member such that the heat collecting medium enters the collection member through the passage member. In the solar heat absorber according to the present disclosure, the ceramic particles are used as the heat collecting medium. In addition, the present disclosure also provides a solar heat collecting system including the solar heat absorber, and a solar power generation system including the solar heat collecting system.
Type:
Grant
Filed:
December 26, 2016
Date of Patent:
December 7, 2021
Assignee:
INSTITUTE OF MODERN PHYSICS, CHINESE ACADEMY OF SCIENCES
Inventors:
Lei Yang, Xiaofei Gao, Yangyang Yang, Sheng Zhang, Yuan Tian, Jianrong Zhang, Ping Lin
Abstract: The present disclosure relates to image reconstruction with favorable properties in terms of noise reduction, spatial resolution, detail preservation and computational complexity. The disclosed techniques may include some or all of: a first-pass reconstruction, a simplified datafit term, and/or a deep learning denoiser. In various implementations, the disclosed technique is portable to different CT platforms, such as by incorporating a first-pass reconstruction step.
Type:
Grant
Filed:
August 6, 2018
Date of Patent:
December 7, 2021
Assignees:
GENERAL ELECTRIC COMPANY, RENSSELAER POLYTECHNIC INSTITUTE
Inventors:
Lin Fu, Sathish Ramani, Jie Tang, Bruno Kristiaan Bernard De Man, Jed Douglas Pack, Jiang Hsieh, Ge Wang