Abstract: Methods and systems and related compositions for separating through a solid matrix a mixture comprising a nucleic acid together with a target compound having a water solubility equal to or greater than 0.01 mg per 100 mL, which can be used for managing fluid flow, biochemical reactions and purification of the nucleic acid or other target analytes.

Abstract: The invention provides scFv antibodies and monoclonal antibodies that bind to and decrease an activity of Carbonic Anhydrase IX (G250). Also provided are the methods of treating and/or preventing cancer, such as renal clear cell cancer. Also provided are methods of identifying a carbonic anhydrase IX (G250) protein. The invention additionally provides methods of modifying immune effector cells, and the immune effector cells modified thereby.

Abstract: The present invention relates to an EPRS (glutamyl-prolyl-tRNA synthetase) protein or a fragment thereof. The EPRS protein of the present invention or fragment thereof may bind to PCBP2 protein to activate the MAVS signaling pathway, and thus it has anti-RNA viral effects, thereby being effective for preventing or treating a RNA viral infectious disease.

Abstract: The present invention discloses stimuli-sensitive protein conjugate which can make supramolecular protein assemblies and methods for using the same. The present invention provides simple and rational process for construction of said stimuli-sensitive spherical protein assemblies through supramolecular chemical strategy.

Abstract: Labeled probes, and methods of use thereof, comprise a Cas polypeptide conjugated to gRNA that is specific for target nucleic acid sequences, including genomic DNA sequences. The probes and methods can be used to label nucleic acid sequences without global DNA denaturation. The presently-disclosed subject matter meets some or all of the above identified needs, as will become evident to those of ordinary skill in the art after a study of information provided in this document.

Abstract: A gaging apparatus and method for automation of a shoemaking process are provided for automating a shoemaking process. According to the method, the gaging apparatus obtains operation data according to the gaging process of drawing a gaging line on a boundary between the upper and the sole for shoe manufacturing, and generates trajectory data for the boundary based on the operation data. Based on the trajectory data, the gaging apparatus generates robot trajectory data for performing a buffing and bonding process after the gaging process and transmits it to a shoemaking robot.

Abstract: A microscopy system includes a gas cluster beam system configured for generating a beam of gas clusters directed toward a sample to irradiate a sample and mill away successive surface layers from the sample, a scanning electron microscope system configured for irradiating the successive surface layers of the sample with an electron beam and for imaging the successive surface layers of the sample in response to the irradiation of the surface layer, and a processor configured for generating a three dimensional image of the sample based on the imaging of the successive layers of the sample.

Abstract: Some embodiments described herein relate to cells which have been genetically engineered to release a polypeptide when a population of the cells reaches a desired density. In some embodiments, the released polypeptide may be a therapeutic polypeptide. In some embodiments, the therapeutic polypeptide kills tumor cells or which inhibits the growth of tumor cells.

Abstract: A packet data unit session establishment method and network entity performing the same is disclosed. User equipment (UE) may establish registration with the core network through a first access network when the UE is registered in a core network through a second access network belonging to the network and a first PDU session is established through the second access network. The UE may transmit a non-access stratum (NAS) message including a PDU session identifier (ID) that is the same as an ID of the first PDU session to an access and mobility management function (AMF).

Abstract: Provided is a pyrolysis gasification apparatus for solid refuse fuel. The apparatus includes: a superheated steam housing formed in a cylindrical shape and installed in a horizontal direction, in which superheated steam is injected into the superheated steam housing; a screw casing formed in a tubular shape extending from one end to the other end inside the superheated steam housing and installed in the horizontal direction inside the superheated steam housing, in which solid refuse fuel (SRF) is introduced into the screw casing; a conveying screw with a plurality of screw blades on an outer peripheral surface, the conveying screw being installed inside the screw casing in the horizontal direction and rotating to convey the solid refuse fuel; and a superheated steam supplier for supplying superheated steam into the superheated steam housing, in which the superheated steam may move through a movement pat.

Abstract: One embodiment of the present invention provides an optical imaging apparatus using a metamaterial including a metamaterial array sensor which includes a plurality of unit cells made of a metamaterial and is positioned adjacent to an observation object, an imaging beam providing unit which provides an imaging beam toward the metamaterial array sensor, a control beam providing unit which controls a control beam provided to the unit cell to block the imaging beam incident on the unit cell, and an imaging beam measuring unit which measures a unit cell imaging beam transmission amount passing through the unit cell by measuring an imaging beam transmission amount of the metamaterial array sensor when the imaging beam passes through the unit cell and an imaging beam transmission amount of the metamaterial array sensor when the control beam is focused on the unit cell to block the imaging beam incident on the unit cell.

Abstract: The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect both DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.

Abstract: A textile-reinforced concrete road paving apparatus and a method of repairing concrete road pavement can minimize use of construction equipment by using the textile-reinforced concrete road paving apparatus integrally formed to consecutively cut concrete, dispose a reinforcement material, and construct a repaired cross section so as to reduce a construction period, thereby remarkably reducing construction costs. Further, a textile grid reinforcement material, which is a noncorroding reinforcement material, is applied to form the repaired cross section of the concrete road pavement so as to prevent concrete from being detached due to corrosion. Further, a textile reinforced grid is precisely disposed at a required position, and thus the thicknesses of the primary and secondary concrete pavement are precisely adjusted, and thus construction precision can be increased.

Abstract: A deep neural network models semiconductor devices. Measurements of test transistors are gathered into training data including gate and drain voltages and transistor width and length, and target data such as the drain current measured under the input conditions. The training data is converted by an input pre-processor that can apply logarithms of the inputs or perform a Principal Component Analysis (PCA). Rather than use measured drain current as the target when training the deep neural network, a target transformer transforms the drain current into a transformed drain current, such as a derivative of the drain current with respect to gate or drain voltages, or a logarithm of the derivative. Weights in the deep neural network are adjusted during training by comparing the deep neural network's output to the transformed drain current and generating a loss function that is minimized over the training data.

Abstract: Disclosed herein are a method for automated fuzzing for an IoT device based on automated reset and an apparatus using the same. The method includes loading, by the apparatus, a fuzzing agent into an IoT device based on firmware; monitoring, by the apparatus, the status of processing of fuzzing input by the IoT device based on the fuzzing agent; collecting, by the apparatus, fuzzing data corresponding to occurrence of a crash based on hooking using the fuzzing agent when the crash occurs in the IoT device; and resetting, by the apparatus, the IoT device based on the fuzzing agent.

Abstract: The method for manufacturing a solid electrolyte using an LLZ material for a lithium-ion battery comprises the steps of: providing a starting material in which lanthanum nitrate [La(NO3)3.6H2O] and zirconium nitrate [ZrO(NO3)2.6H2O] are mixed at a mole ratio of 3:2; forming an aqueous solution by dissolving the starting material; forming a precipitate by putting ammonia, which is a complex agent, and sodium hydroxide, which adjusts the pH of a reactor, into the aqueous solution, mixing the same, and then co-precipitating the mixture; forming a primary precursor powder by cleaning, drying and pulverizing the precipitate; forming a secondary precursor powder by mixing lithium powder [LiOH.H2O] with the primary precursor powder and ball-milling the mixture so as to solidify the lithium; and forming a solid electrolyte powder by heat-treating the secondary precursor powder.

Abstract: A method and apparatus are disclosed which relate generally to worker-scheduling technology in a serverless cloud-computing environment, and more particularly, to technology that allocates workers for executing functions on a micro-function platform which provides a function-level micro-service. The method and apparatus process a worker allocation task in a distributed manner as two-step pre-allocation schemes before a worker allocation request occurs, and pre-allocates workers required for a service using a function request period and a function execution time, thus minimizing scheduling costs incurred by worker allocation requests.

Abstract: A method for measuring one or more quantities characterizing a composition of a medium includes causing a first non-uniform spatially varying optical signal to impinge on a portion of the medium, processing a second optical signal emitted from the medium in response to the first optical signal including determining characteristics of a spatial variation of the second optical signal, and determining the one or more quantities characterizing the composition of the medium based on the characteristics of the spatial variation of the second optical signal.

Abstract: Disclosed is a method for infiltrating a porous structure with a precursor solution by means of humidification. The infiltration method with a precursor solution using moisture control comprises the steps of: (S1) providing a substrate having porous structures deposited thereon; (S2) depositing, by electrospraying, a precursor solution on the substrate having porous structures deposited thereon; (S3) humidifying the porous structures having the precursor solution deposited thereon; and (S4) sintering the humidified porous structures.

Abstract: Provided is an image recognition processor. The image recognition processor includes a plurality of nano cores arranged in rows and columns and configured to perform a pattern recognition operation on an input feature using a kernel coefficient in response to each instruction, an instruction memory configured to provide the instruction to each of the plurality of nano cores, a feature memory configured to provide the input feature to each of the plurality of nano cores, a kernel memory configured to provide the kernel coefficients to the plurality of nano cores, and a functional safety processor core configured to receive a result of a pattern recognition operation outputted from the plurality of nano cores to detect the presence of a recognition error, and perform a fault tolerance function on the detected recognition error.