Patents Assigned to INSTITUTE
-
Patent number: 12288679Abstract: A method for full Os isotope static measurement by NTIMS includes steps of: selecting and weighing rock samples, and dissolving the rock samples to obtain dissolution liquid; chemically separating Os from the dissolution liquid to obtain purified Os solution; loading the purified Os solution on a Pt filament to obtain a sample to be determined; selecting Faraday cups and ion counters, as well as 1012? and 1013? amplifiers in NTIMS based on natural abundances of different Os isotopes, thereby establishing a cup configuration for the full Os isotope static measurement; establishing a yield calibration method for ICs; performing full Os isotopes static measurement based on the yield-calibrated ion counters and gain-calibrated faraday cups; and processing analytical data to obtain a final data of Os isotopic composition. The method enables the determination of the full Os isotope and oxygen isotope compositions of low-content or small-size samples.Type: GrantFiled: April 22, 2024Date of Patent: April 29, 2025Assignees: Guangzhou Institute of Geochemistry (GIG), Chinese Academy of Sciences (CAS)Inventor: Guiqin Wang
-
Patent number: 12286701Abstract: A preparation method for a tungsten sulfide (WS2) solid lubricating film based on high power impulse magnetron sputtering (HiPIMS) is provided. The preparation method includes the following steps: step 1: depositing a metal conductive film on a surface of a WS2 target; step 2: using magnetic field sputtering to remove the metal conductive film in a target sputtering area on the surface of the WS2 target, thereby obtaining a first WS2 target; and step 3: performing the HiPIMS on the first WS2 target to obtain the WS2 solid lubricating film. The preparation method can achieve stable glow discharge of a WS2 target and use the high deposition energy of HiPIMS to prepare the WS2 solid lubricating film with high compactness and excellent wear resistance.Type: GrantFiled: March 20, 2024Date of Patent: April 29, 2025Assignees: Taizhou University, Wenling Gonglian Measuring & Cutting Tool Technology Service Center Co., Ltd, Wenling Research Institute of Taizhou UniversityInventors: Ping Zhang, Puyou Ying, Jianbo Wu, Vladimir Levchenko, Tao Yang, Changhong Lin, Jian Wu
-
Patent number: 12286621Abstract: Disclosed herein include methods, compositions, and systems for extending particle-associated oligonucleotides. In some embodiments, the methods of extending particle-associated oligonucleotides enable efficient methods of preparing a library of barcoded beads. It is also provided, in some embodiments, hydrogel beads degradable upon application of a chemical stimulus that comprise releasably attached oligonucleotides.Type: GrantFiled: September 27, 2019Date of Patent: April 29, 2025Assignee: California Institute of TechnologyInventors: Eduardo da Veiga Beltrame, Jase Gehring, Akshay Tambe, Lior S. Pachter, Taleen Dilanyan
-
Patent number: 12289740Abstract: A method for receiving a downlink channel by a terminal in a wireless communication system includes: receiving, from a base station, first information related to a guard band in a first resource region located in one carrier; receiving, from the base station, second information related to multiple resource sets, each of which is identified by the guard band in the first resource region on the basis of the first information; and receiving, from the base station, a downlink channel on a resource indicated by the second information to be available for reception of the downlink channel.Type: GrantFiled: March 30, 2023Date of Patent: April 29, 2025Assignee: WILUS INSTITUTE OF STANDARDS AND TECHNOLOGY INC.Inventors: Minseok Noh, Kyungjun Choi, Jinsam Kwak
-
Patent number: 12285469Abstract: Methods of making the M or L complex of the botulinum neurotoxin E with its associated neurotoxin binding protein(s) (NBP), and methods of using to treat pain and wrinkles by injecting locally. Methods of making and isolating the L and M complex comprise a multi-step process of: providing a bacterial cultured media comprising the complex of botulinum neurotoxin E and neurotoxin binding proteins; centrifuging and pelletizing the cultured media; stirring the pelletized culture at 0 to 10° C. over a period of 4 to 24 hours; centrifuging the stirred solution to obtain a supernatant; precipitating the supernatant and filtering to obtain the precipitate; and dissolving the precipitate, centrifuging and filtering to obtain a solution comprising M complex and/or L complex of botulinum neurotoxin E and its NBP; and passing the solution through a functionalized sephadex ion exchange column to isolate the complex.Type: GrantFiled: March 11, 2024Date of Patent: April 29, 2025Assignee: Institute of Advanced Sciences, Inc.Inventors: Bal Ram Singh, Raj Kumar
-
Patent number: 12287268Abstract: The present disclosure relates to a field programmable gate array (FPGA)-based multi-channel dynamic light scattering (DLS) autocorrelation system and method. The system includes a DLS generation apparatus, a photon correlator, and a host computer, where the photon correlator includes an FPGA and a universal serial bus (USB) communication module; the DLS generation apparatus is connected to the FPGA; the FPGA is configured to count and perform correlation calculation on photon pulses generated by the DLS generation apparatus; the USB communication module is connected to the host computer; the FPGA includes a dual counter module and a correlation calculation module; the dual counter module is connected to the DLS generation apparatus and the correlation calculation module; the correlation calculation module is connected to the USB communication module; the dual counter module includes a plurality of dual counters; and the correlation calculation module includes a plurality of correlators.Type: GrantFiled: January 19, 2022Date of Patent: April 29, 2025Assignee: National Institute of Metrology, ChinaInventors: Lu Huang, Yuqi Fang, Sitian Gao, Miao Sun
-
Patent number: 12289390Abstract: A node includes: a communication module that recovers a clock signal of another node; a high-precision clock module; a first phase/frequency comparison module; a time estimation section that estimates time information of each node; a counter value correction section that corrects a counter value; a fractional PLL; a second phase/frequency comparison module; and a division ratio correction section that corrects a division ratio of the fractional PLL.Type: GrantFiled: February 25, 2022Date of Patent: April 29, 2025Assignee: National Institute of Information and Communications TechnologyInventors: Yuichiro Yano, Tetsuya Ido, Motoaki Hara
-
Patent number: 12288348Abstract: A method for depth estimation performed by a depth estimation system associated with an agent includes determining a first depth of a first image and a second depth of a second image, the first image and the second image being captured by a sensor associated with the agent. The method also includes generating a first 3D image of the first image based on the first depth, a first pose associated with the sensor, and the second image. The method further includes generating a warped depth image based on transforming the first depth in accordance with the first pose. The method also includes updating the first pose based on a second pose associated with the warped depth image and the second depth, and updating the first 3D image based on the updated first pose. The method further includes controlling an action of the agent based on the updated first 3D image.Type: GrantFiled: June 29, 2023Date of Patent: April 29, 2025Assignee: TOYOTA RESEARCH INSTITUTE, INC.Inventors: Jiexiong Tang, Rares Andrei Ambrus, Vitor Guizilini, Adrien David Gaidon
-
Patent number: 12286485Abstract: Provided herein are anti-CD24 antibodies that selectively bind human CD24 expressed in cancer cells, but not human CD24 expressed in non-cancerous cells, and the use of such antibodies in cancer therapy.Type: GrantFiled: May 13, 2019Date of Patent: April 29, 2025Assignees: OncoC4, Inc., Children's Research Institute, Children's National Medical CenterInventors: Yang Liu, Pan Zheng, Rhonda Flores, Hung-Yen Chou, Zhihong Xue, Peiying Ye, Martin Devenport
-
Patent number: 12286152Abstract: A steering wheel-based HMI system for a vehicle includes a steer-by-wire system and a control module. The steer-by-wire system includes a steering wheel and a torque feedback unit mechanically connected to the steering wheel. The control module is communicatively connected to the torque feedback unit. The control module is configured to identify a communication, gather information about user securement of the steering wheel, and operate the torque feedback unit to apply a supplementary torque to the steering wheel for haptically issuing the communication through the steering wheel. The supplementary torque has a magnitude that is scaled based on the information about user securement of the steering wheel.Type: GrantFiled: June 24, 2021Date of Patent: April 29, 2025Assignee: Toyota Research Institute, Inc.Inventors: Hiroshi Yasuda, Manuel Ludwig Kuehner
-
Patent number: 12285427Abstract: This invention establishes a new paradigm for treatment of Parkinson's disease (PD) by eliminating senescent cells that reside in or around the site of the disease pathophysiology. Exposure of test subjects to the herbicide paraquat (PQ) increases the risk for developing Parkinson's disease. The data in this disclosure show that PQ induces a senescence arrest and SASP in astrocytes, in culture and in vivo in mice, and senescent cell markers were present in astrocytes in midbrain tissue from PD patients. In a transgenic mouse model, senescent cell ablation protected against PQ-induced PD-like neuropathology. Removal of senescent cells from affected sites using small molecule agents that specifically target senescent cells can help prevent or ameliorate signs and symptoms of the disease.Type: GrantFiled: August 7, 2023Date of Patent: April 29, 2025Assignees: Unity Biotechnology, Inc., Mayo Foundation for Medical Education and Research, Buck Institute for Research on AgingInventors: Remi-Martin Laberge, Judith Campisi, Marco Demaria, Bennett G. Childs, Jan M. A. Van Deursen, Nathaniel David, Alain Philippe Vasserot
-
Patent number: 12285416Abstract: Disclosed herein are methods of reducing muscle contraction in a diaphragm or peripheral muscle(s) of a patient sufficient to permit a surgical procedure. The methods may comprise the step of administering an oxime or pharmaceutically acceptable salt thereof to a subject in need thereof in an amount sufficient to achieve said reduced muscle contraction/neuromuscular blockade. Kits and articles of manufacture comprising a container having a label and a composition are also disclosed.Type: GrantFiled: June 21, 2022Date of Patent: April 29, 2025Assignee: Battelle Memorial InstituteInventors: Brian L. Burback, Jessica Catherine Bright, Jerry D. Johnson
-
Patent number: 12285793Abstract: A forming device and a forming method for a part with a regular cross-section are provided, and relates to the technical field of metal member forming and manufacturing. A part to be formed is heated by a part heating temperature control assembly to obtain required microstructure evolution, so that the forming performance is improved. A temperature control die assembly can be heated by setting die heating assemblies, so that hot stamping, die quenching and stress relaxation can be carried out. The internal stress state of the part is controlled by an axial force control assembly.Type: GrantFiled: March 31, 2024Date of Patent: April 29, 2025Assignees: DALIAN UNIVERSITY OF TECHNOLOGY, AVIC MANUFACTURING TECHNOLOGY INSTITUTEInventors: Kailun Zheng, Dechong Li, Lihua Du, Yujie Han
-
Patent number: 12286594Abstract: A fluidized bed reactor, a device, and a method for producing low-carbon olefins from oxygen-containing compound are provided. The fluidized bed reactor includes a reactor shell, a reaction zone, a coke control zone and a delivery pipe, where there are n baffles arranged in the coke control zone, and the n baffles divide the coke control zone into n sub-coke control zones which include a first sub-coke control zone, a second sub-coke control zone, and an nth sub-coke control zone; at least one catalyst circulation hole is provided on each of the n-1 baffles, so that the catalyst flows in an annular shape in the coke control zone, where n is an integer. The device and method can be adapted to a new generation of DMTO catalyst, and the unit consumption of production ranges from 2.50 to 2.58 tons of methanol/ton of low-carbon olefins.Type: GrantFiled: October 16, 2020Date of Patent: April 29, 2025Assignee: DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCESInventors: Mao Ye, Tao Zhang, Jinling Zhang, Shuliang Xu, Hailong Tang, Xiangao Wang, Cheng Zhang, Jinming Jia, Jing Wang, Hua Li, Chenggong Li, Zhongmin Liu
-
Patent number: 12288028Abstract: Improvement is made in performance of a trained neural network that uses positional information indicating a position at which each token included in an input sequence is present in the input sequence.Type: GrantFiled: July 6, 2020Date of Patent: April 29, 2025Assignee: NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGYInventors: Kehai Chen, Rui Wang, Masao Uchiyama, Eiichiro Sumita
-
Publication number: 20250128202Abstract: Provided is a carbon dioxide capturing apparatus comprising: a reaction tower including a carbon dioxide adsorption unit or a carbon dioxide absorption unit which adsorbs or absorbs carbon dioxide from exhaust gas; desorption tower connected to the reaction tower and including an adsorbent heating unit for heating an adsorbent circulating inside or an absorbent heating unit for heating an absorbent circulating inside; an adsorbent or absorbent which circulates in the reaction tower and the desorption tower and alternately adsorbs and desorbs carbon dioxide or alternately absorbs and desorbs carbon dioxide; and a heat exchange unit which desorbs carbon dioxide from the adsorbent on which carbon dioxide is adsorbed or the absorbent in which carbon dioxide is absorbed, through heat exchange between the adsorbent on which carbon dioxide is adsorbed and the heated adsorbent, or between the absorbent in which carbon dioxide is absorbed and the heated absorbent, wherein the adsorbent on which carbon dioxide is adsorType: ApplicationFiled: October 29, 2024Publication date: April 24, 2025Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGYInventors: Yong Ki PARK, Hwi Min SEO, Ki Woong KIM, Dae Jin KIM
-
Publication number: 20250128894Abstract: The present disclosure discloses a pneumatic conveying system and an optimized configuration method. The pneumatic conveying system uses a pressure-type elephant bionic trunk conveying pipeline to convey a material or uses a suction-type elephant bionic trunk conveying pipeline to convey a material, wherein the pressure-type elephant bionic trunk conveying pipeline is a pipeline with a gradually enlarged inner diameter, and the suction-type elephant bionic trunk conveying pipeline is a pipeline with a gradually reduced inner diameter.Type: ApplicationFiled: September 27, 2023Publication date: April 24, 2025Applicants: JIANGSU XCMG CONSTRUCTION MACHINERY RESEARCH INSTITUTE LTD., JIANGSU XCMG STATE KEY LABORATORY TECHNOLOGY CO., LTD.Inventors: Yang LI, Xiaopei LI, Jianquan SANG, Haiqiang LI
-
Publication number: 20250128935Abstract: A microelectromechanical sensing device includes a substrate, a plurality of support structures and a sensing structure. The sensing structure is supported by the plurality of support structures and is disposed above the substrate. The sensing structure includes a first dielectric layer, an electrode layer, a sensing layer and a second dielectric layer. The first dielectric layer has a dielectric top surface coplanar with the support top surface of each of the support structures. The electrode layer is disposed on the first dielectric layer and directly contacts the plurality of support structures. The sensing layer is disposed on the first dielectric layer and a projection of the sensing layer toward the substrate does not overlap the plurality of support structures. The second dielectric layer is disposed on the electrode layer and the sensing layer, wherein the first dielectric layer and the second dielectric layer are made of the same material.Type: ApplicationFiled: October 18, 2024Publication date: April 24, 2025Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Ming-Fa CHEN, Bor-Shiun LEE, Chin-Jou KUO
-
Publication number: 20250130193Abstract: The present invention provides a method for sensing volatile fatty acid with high sensitivity and measuring volatile fatty acid with high accuracy and provides a device for such sensing and measurement.Type: ApplicationFiled: September 16, 2022Publication date: April 24, 2025Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCEInventors: Jin KAWAKITA, Izumi ICHINOSE
-
Publication number: 20250133765Abstract: A semiconductor device, comprising: a substrate; a plurality of bit lines located on the substrate, and disposed parallel to each other in a first horizontal direction; a plurality of word lines located on the bit line, and disposed parallel to each other in a second horizontal direction substantially perpendicular to the first horizontal direction; a plurality of channel patterns arranged in an array on the bit line, the plurality of channel patterns; a gate insulating pattern located between the plurality of channel patterns and the plurality of word lines; a plurality of switching insulating layers each formed on an upper surface of each of the plurality of channel patterns, at least a portion of which has a thickness that an electron can penetrate upon application of a voltage; and a plurality of control electrodes disposed parallel to each other to connect the plurality of switching insulating layers, is disclosed.Type: ApplicationFiled: May 30, 2024Publication date: April 24, 2025Applicant: TAESUNG ENVIRONMENTAL RESEARCH INSTITUTE CO., LTD.Inventors: Gi Yeol YUN, Seok Man Kim, Chai Rok Lim, Hyeok-je Jeong, Myung-Kon Jo