Abstract: The present application relates to hybridization chain reaction (HCR). In particular, compositions and methods are presented for ultrasensitive molecular detection using HCR signal amplification. Some embodiments and methods involve cooperative probe junctions, reporter-labeled probes, and nonlinear HCR signal amplification.

Abstract: Disclosed herein is a class of molecules termed remodilins that are effective in treating asthma, pulmonary fibrosis, and associated disorders. The molecules ameliorate asthma and pulmonary fibrosis symptoms by various mechanisms, including inhibiting airway smooth muscle contractile protein accumulation, reducing airway constrictor hyperresponsiveness, inhibiting bronchial fibroblast transformation into myofibroblasts, and/or treating or preventing airway or pulmonary fibrosis.

Abstract: An integrated filter material, a preparation method and an application. The filter material is composed of a commercial dust removal filter material and a catalyst that is grown on the filter material and that has a function of simultaneously decomposing nitrogen oxides and dioxins. In the preparation method, a precursor solution of manganese and cerium oxides is impregnated on the filter material, and manganese and cerium oxides are grown on the filter material by means of a chemical reaction; and vanadium oxychloride is used as a precursor of vanadium oxide and is impregnated on the filter material, reacts in water, and prepared by drying, hydrothermal and other processes. The composite filter material may remove three kinds of pollutants in flue gas at the same time, and the catalyst is firmly loaded and does not easily fall off.

Abstract: A system for optically modulating a plurality of optical channels includes a power delivery module adapted to convert a coherent light beam into a plurality of optical channels, at least one optical modulator, optically coupled to the power delivery module, the at least one optical modulator adapted to optically modulate each of the plurality of the optical channels, and a vacuum chamber having a trapping plane therein, the vacuum chamber adapted to generate an addressable array of trapped particles at the trapping plane, wherein each of the plurality of optical channels is optically coupled to at least one of the trapped particles of the addressable array.

Abstract: Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids or the modification of nucleic acids or proteins, including editing a single site within the genome of a cell or subject, e.g., within the human genome. In some embodiments, fusion proteins of nucleic acid programmable DNA binding proteins e.g., GeoCas9 or variants thereof, and effector domains, e.g., deaminase domains, are provided. In some embodiments, methods for targeted nucleic acid editing or protein modification are provided. In some embodiments, reagents and kits for the generation of targeted nucleic acid editing proteins, e.g., fusion proteins of a GeoCas9 and effector domains, are provided.

Abstract: An operation method of a repeater relaying wireless communications between a base station and at least one terminal in a communication system may include: transmitting, to the base station, a first capability report including information on beam-related capability supported by the repeater; transmitting, to the base station, a first request signal for requesting to perform first configuration for coverage extension of the repeater; receiving, from the base station, information on the first configuration configured based on the first capability report and the first request signal; and relaying the wireless communications between the base station and the at least one terminal based on one or more beams formed based on the received first configuration.

Abstract: Provided is a method for preparing bencaosome comprising the steps of: mixing one or more lipid components with any one or more of the following: nucleic acid, compound and macromolecules, and treating the obtained mixture by heating. Also provided is a method for extracting decoctosome from plants comprising the steps of: preparing an extract of the plant with a solvent; performing differential centrifugation to the extract; resuspending the precipitates with an aqueous solution to provide the decoctosome.

Abstract: Recombinant adenovirus genomes that include an exogenous open reading frame (ORF) and a self-cleaving peptide coding sequence are described. Optimal placement of the exogenous genes for minimal impact on viral kinetics is further disclosed. Therapeutic applications of the recombinant adenoviruses are also described.

Abstract: The present invention relates to a radiant tube apparatus disposed in a heat treatment facility to perform a heat treatment of a strip and a method for manufacturing the same. The radiant tube apparatus includes a tube having an internal pipe, wherein the tube has a first continuous pattern and a second continuous pattern extending side by side and spaced apart from each other at a predetermined distance on a surface, and, in each of the first continuous pattern and the second continuous pattern, a plurality of unit patterns having a predetermined height from the surface are connected to each other in a longitudinal direction.

Abstract: The invention provides a method for homogenized coherent excitation of a sample for determining molecular structure. The method includes selecting a monochromatic coherent light, homogenizing the monochromatic coherent light; irradiating the sample with the homogenized monochromatic light; collecting the Raman scattered light to obtain a profile and analyzing the profile to obtain chemical specific signature of the sample. The invention also provides a method for obtaining two dimensional imaging of a sample using irradiation of large sample area by homogenized monochromatic light without compromise in spatial resolution. A system for homogenized coherent excitation of a sample for determining molecular structure is also provided.

Abstract: The present invention provides methods of screening for compounds that interfere with the interaction between ERG. ETV1, ETV4 or ETV5 and mSWI/SNF (BAF) chromatin remodeling complex proteins. Included are methods of screening for compounds that interfere with the interaction between ERG, ETV1, ETV4 or ETV5 and BAF155. Methods of treating prostate cancer with compounds that interfere with the interaction between ERG, ETV1, ETV4 or ETV5 and mSWI/SNF (BAF) chromatin remodeling complex proteins are also provided.

Abstract: Provided herein are screening methods to select catalysts having a desired set of target properties from a reference catalyst, and catalysts so obtained, as well as related catalysts material, composition, methods and systems.

Abstract: Optically computed phase imaging systems and methods are provided. An example system includes an interferometer configured to output 3D spatial-spectral data of a sample including an interferometric signal and an optical computation assembly having a spatial light modulator configured to modulate the 3D spatial-spectral data with a modulation pattern. The modulation pattern modulates the interferometric signal along a spectral dimension to select a depth to obtain a sample signal at the selected depth and modulates the interferometric signal along a first spatial dimension to create a waveform to facilitate phase extraction. The system further includes a detector configured to detect 2D spatial data of the sample. The system further includes a processor coupled to a memory, the processor configured to process the 2D spatial data to extract phase information of the sample.

Abstract: Provided is a method performed by a system for distribution storage of blockchain transaction data based on an erasure code. The method includes performing RS encoding on a predetermined number of blockchain transaction original data; and after the RS encoding is performed, applying LRC encoding technique to blockchain transaction original data (LRC-encoded original data), which needs to be accessed high speed, among the RS-encoded transaction original data to encode and store the LRC-encoded original data, and repairing the LRC-encoded original data through decoding.

Abstract: Provided are a device for measuring the amount of snowfall and a method of controlling the same, the device including a bottom plate, a graduated ruler extending upward from the bottom plate, an image capturing unit configured to capture an image of the graduated ruler and an upper portion of snow deposited on the bottom plate by using an image capturing device, a measurement unit configured to measure the amount of snowfall based on information on the captured image, and a snow removing unit configured to push out the deposited snow to the outside of the bottom plate while moving in a direction from one side to the other side of the bottom plate.

Abstract: A differential proportional temperature measurement circuit and method based on bidirectional constant voltage drive is proposed. The circuit and method applied to the precision temperature measurement of spacecraft, the main components include a bidirectional constant voltage source proportional bridge circuit, a differential and single-ended amplifier circuit, an analog-to-digital conversion circuit, a digital filter circuit, a data processing circuit and an isolated filter power supply circuit. The method adopts the bidirectional constant voltage drive technology, and enlarges and measures the difference between the voltage values of the reference resistor and the resistance to be measured by improving the sensing bridge of the ordinary commutation proportional method, and suppresses the long-term drift of the excitation unit and the voltage measurement unit. The method can meet the requirements of temperature measurement resolution of ?K magnitude and the power spectral density of ?K/Hz1/2 (0.

Abstract: An agricultural composition comprises living microorganisms encapsulated in polymer gel microbeads which are applied onto seeds. In another embodiment, an agricultural composition comprises living microorganisms encapsulated in polymer gel macroheads for planting with seeds in soil. In another embodiment, an agricultural composition comprises living microorganisms immobilized in a polymer gel matrix that is coated on a seed.

Abstract: A technology enabling a terminal to receive acknowledgement (ACK)/negative ACK (NACK) information about data transmitted from the terminal is provided. The method includes receiving cyclic shift information for a reference signal from the base station; transmitting, to the base station, the data and a reference signal which is cyclic-shifted using a cyclic shift value, the cyclic shift value being determined based on a dynamic cyclic shift value mapped one-to-one to the cyclic shift information for the reference signal; and receiving, from the base station, the ACK/NACK information about the transmitted data through a radio resource of a downlink channel, the radio resource of the downlink channel being identified based on a modifier mapped one-to-one to the cyclic shift information for the reference signal.

Abstract: A thermal management system includes a refrigerant system and a coolant system. The refrigerant system includes a compressor, an indoor heat exchanger, a first flow regulating device, a first heat exchanger and an outdoor heat exchanger. The outdoor heat exchanger includes a first port and a second port. The first flow regulating device has a bi-directional throttling function. The first heat exchanger includes a first heat exchange section and a second heat exchange section. The thermal management system has a heating mode and a cooling mode which can be achieved by the same first flow regulating device. A control method of the thermal management system is also disclosed.

Abstract: Fissile target materials are provided. The fissile target materials can include a target substrate and a capturing layer operably interfacing with at least one surface of the target substrate. Fission fissile target materials are also provided that can include a target substrate comprising at least one fissile atom and a capturing layer operably interfacing with at least one surface of the target substrate. The capturing layer can include at least one fission product.