Patents Assigned to INSTITUTE
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Publication number: 20250122262Abstract: The specification describes an antibody capture process comprising (i) obtaining a biological sample comprising antibodies, (ii) contacting the biological sample with recombinant pIgR or a dIgA-binding variant, wherein the pIgR or variant binds dIgA and forms a pIgR-dIgA complex. The process may further comprise (iii) directly or indirectly assessing the level of the pIgR-dIgA complex or the level of a complex between pIgR-dIgA and an antigen of interest. There is also an antibody capture process for determining gut wall integrity in a test subject, wherein the level or ratio of SIgA to dIgA is compared to a corresponding level or ratio from a control subject. The specification provides kits embodying the process and recombinant pIgR when used for, or for use, in capturing or detecting dIgA and/or IgM.Type: ApplicationFiled: November 6, 2024Publication date: April 17, 2025Applicant: The MacFarlane Burnet Institute for Medical Research and Public Health LtdInventors: David Andrew Anderson, Mary Louise Garcia, Nadine Carmel Barnes, Khayriyyah Mohd Hanafiah, Alan Lee Landay
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Publication number: 20250121317Abstract: A carbon dioxide capture and sequestration system is provided and includes a capture unit, a storage unit, a sequestration unit and a floating body unit. The capture unit is used for capturing carbon dioxide in the atmosphere; the storage unit is connected with the capture unit and is used for storing the carbon dioxide captured by the capture unit; the sequestration unit is connected with the storage unit and is used for sequestrating the carbon dioxide discharged by the storage unit. The capture unit, the storage unit and the sequestration unit are all arranged on the floating body unit so as to float on the sea. The system can sequestrate the captured carbon dioxide in situ and reduce the transportation cost.Type: ApplicationFiled: December 27, 2024Publication date: April 17, 2025Applicants: HUANENG CLEAN ENERGY RESEARCH INSTITUTE, SHANGHAI SHIDONGKOU NO. 2 POWER PLANT HUANENG INTERNATIONAL POWER CO., LTD.Inventors: Rong LIU, Zhaofang ZHENG, Shiwang GAO, Lianbo LIU, Hongwei NIU, Dongfang GUO, Shiqing WANG
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Publication number: 20250122462Abstract: One embodiment of the present invention provides an ecotoxicity monitoring device using Aliivibrio fischeri, and an ecotoxicity monitoring method using the same. The ecotoxicity monitoring device includes a reaction tank module, an Aliivibrio fischeri culture unit, a diluted water supply unit, a sample supply unit, an optical measurement unit, a control unit and an analysis unit, wherein the analysis unit is configured to calculate a correction coefficient based on the initial light quantity value of a reference reaction tank measured through the optical measurement unit and the final light quantity value measured after a predetermined time has elapsed, and calculate the corrected light quantity values of a sample reaction tank and a dilution reaction tank based on the calculated correction coefficient.Type: ApplicationFiled: October 10, 2024Publication date: April 17, 2025Applicants: KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY, DONGMOONENT CO., LTD.Inventors: Kyoung Jin LEE, Dong Kwon Lee, Jong Young Kim, Chul Woo Park, Moon Jin Lee, Hoon Choi
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Publication number: 20250122210Abstract: The disclosure relates to compounds that act as inhibitors of KRAS; pharmaceutical compositions comprising the compounds; and methods of treating or preventing disorders, including cancer and other proliferation diseases.Type: ApplicationFiled: June 29, 2022Publication date: April 17, 2025Applicant: DANA-FARBER CANCER INSTITUTE, INC.Inventors: Jianwei Che, Guangyan Du, Tinghu Zhang, Wenzhi Ji
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Publication number: 20250120964Abstract: The present invention relates to use of a novel compound for prevention or treatment of brain cancer, where the novel compound may function as a molecular gluc.Type: ApplicationFiled: October 15, 2024Publication date: April 17, 2025Applicants: ASTROGEN, INC., KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCESInventors: Su-Kyeong Hwang, Hyung Chul Ryu, Hae-June Lee, Soo-Ho Lee
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Publication number: 20250124726Abstract: Systems and methods are provided for determining intoxication in a driver. The system can receive data of a driver's face over a time interval and for each frame of the data, determine one or more parameters associated with eye movements and characteristics of the driver. Based on the one or more parameters for each frame, the frames can be featurized into one or more vectors, where each of the one or more vectors corresponds to a parameter of the one or more parameters. A weight can be applied to each of the one or more vectors and based on the weight of each of the one or more vectors, the system can predict whether the driver surpassed an intoxication threshold. If the driver surpassed the intoxication threshold, the system can alter an operating characteristic of a vehicle of the driver.Type: ApplicationFiled: October 11, 2023Publication date: April 17, 2025Applicants: Toyota Research Institute, Inc., Toyota Jidosha Kabushiki KaishaInventors: JOHN H. GIDEON, Guy Rosman, Kimimasa Tamura, Pujitha Gunaratne
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Publication number: 20250126246Abstract: The present invention relates to an image encoding method and an image decoding method. The image decoding method includes partitioning a picture into a plurality of coding units, constructing a coding unit group including at least one coding unit of the plurality of coding units, obtaining coding information in units of one coding unit group, and decoding at least one coding unit of the plurality of coding units included in the coding unit group by using the obtained coding information.Type: ApplicationFiled: December 23, 2024Publication date: April 17, 2025Applicant: Electronics and Telecommunications Research InstituteInventors: Jung Won KANG, Sung Chang LIM, Hyun Suk KO, Ha Hyun LEE, Jin Ho LEE, Dong San JUN, Seung Hyun CHO, Hui Yong KIM, Jin Soo CHOI
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Publication number: 20250122250Abstract: An auxin-degron system kit controlling degradation of a target protein in a non-plant-derived eukaryotic cell, in which the auxin-degron system kit includes a first nucleic acid encoding a mutant TIR1 family protein that has a mutation at an auxin-binding site; an auxin analog having an affinity for the mutant TIR1 family protein; and a second nucleic acid encoding a degradation tag that includes at least a partial Aux/IAA family protein and has an affinity for a complex of the mutant TIR1 family protein and the auxin analog.Type: ApplicationFiled: August 5, 2022Publication date: April 17, 2025Applicants: Inter-University Research Institute Corporation Research Organization of Information and Systems, Kake Educational InstitutionInventors: Masato Kanemaki, Ken-ichiro Hayashi, Takefumi Negishi
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Publication number: 20250122982Abstract: A production and transportation system for natural gas hydrates includes a gas storage reservoir, a plurality of hydrate storage and transportation tanks, a refrigerator, a pressure regulating valve, a liquid storage tank, a living quarter/surrounding user, a hydrate storage reservoir, a plurality of connecting pipes, a plurality of one-way gas valves, one-way liquid valves, and optional liquid pumps. The plurality of hydrate storage and transportation tanks are connected in parallel through the connecting pipes and then connected with an output end of the gas storage reservoir through the pressure regulating valve, the liquid storage tank is connected with the optional liquid pump and then sequentially connected with the plurality of hydrate storage and transportation tanks, and the plurality of hydrate storage and transportation tanks are connected in parallel and then connected with an input end of the living quarter/surrounding user through the optional liquid pump.Type: ApplicationFiled: May 8, 2024Publication date: April 17, 2025Applicant: GUANGZHOU INSTITUTE OF ENERGY CONVERSION, CHINESE ACADEMY OF SCIENCESInventors: Xiaosen LI, Yisong YU, Jianwu LIU, Wenzhe SUN, Zhaoyang CHEN
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Publication number: 20250120676Abstract: Echocardiography deep learning and cardiovascular outcomes are described. An echocardiogram analysis module may include a deep learning model to generate a video output for an input echocardiogram video, the deep learning model comprising a convolutional neural network and at least one dense layer. The echocardiogram analysis module may further include a cardiac prediction generator to generate a cardiac prediction based on video outputs generated for a plurality of input echocardiogram videos of an echocardiogram study, the cardiac prediction comprising a measurement prediction or a classification prediction.Type: ApplicationFiled: October 11, 2024Publication date: April 17, 2025Applicants: The General Hospital Corporation, Beth Israel Deaconess Medical Center, Inc., The Broad Institute, Inc.Inventors: Patrick T. Ellinor, II, Emily S. Lau, Jennifer Ho, Mostafa Al-Alusi, Paolo Di Achille, Puneet Batra, Steven Lubitz
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Publication number: 20250125153Abstract: A method for etching a surface including obtaining a substrate comprising a material; reacting a surface of a substrate with a reactant, comprising a gas or a plasma, to form a reactive layer on the substrate, the reactive layer comprising a chemical compound including the reactant and the material; and wet etching or dissolving the reactive layer with a liquid wet etchant of solvent that selectively etches or dissolves the reactive layer but not the substrate.Type: ApplicationFiled: December 20, 2024Publication date: April 17, 2025Applicant: California Institute of TechnologyInventor: Harold Frank Greer
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Publication number: 20250120358Abstract: The present application discloses a method for improving density-tolerant yield of maize and use thereof, belongs to the field of plant biotechnology breeding. Compared with the Ig1 mutant strain, the LG1/Ig1 heterozygous genotype strain has excellent agronomic characters such as a widened leaf, a larger spike, a reduced empty stalk ratio and/or an increased yield by close planting; compared with the LG1 wild-type strain, the LG1/Ig1 heterozygous genotype material reduces a leaf angle and tassel branch number of maize, and has the effect of increasing the yield by close planting. The method has a wide application prospect in the field of maize high-yield breeding.Type: ApplicationFiled: September 30, 2024Publication date: April 17, 2025Applicants: BIOTECHNOLOGY RESEARCH INSTITUTE OF CHINESE ACADEMY OF AGRICULTURAL SCIENCES, SOUTH CHINA AGRICULTURAL UNIVERSITYInventors: Baobao WANG, Haiyang WANG, Changhe SUN, Di YANG, Zhanchao XIA, Yuelei ZHAO, Xinan ZHOU, Xinle ZHU, Zhigang ZHENG, Yurong XIE, Miaoyun XU
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Publication number: 20250121332Abstract: Articles, systems, and methods related to the separation of at least a first species from at least a second species using nanoporous membranes are generally described.Type: ApplicationFiled: September 7, 2022Publication date: April 17, 2025Applicant: Massachusetts Institute of TechnologyInventors: Rohit N. Karnik, Aaron Persad, Chun Man Chow, Chi David Cheng
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Publication number: 20250126654Abstract: The present disclosure provides a method for executing random access resource selection in UE served by an NTN. The method includes: detecting a synchronization signal block (SSB) transmitted by an NTN cell, based on a predefined communication resource associated with the SSB; determining an identifier (ID) associated with the detected SSB; maintaining assistance information, wherein the assistance information comprises at least one of the following: first information associated with a presentation order of the detected SSB; and second information associated with an available service duration d of a random access resource associated with the detected SSB; selecting one of the detected SSB as a first SSB based on the assistance information when a plurality of SSB are detected; and applying a random access resource associated with the first SSB for performing a random access procedure.Type: ApplicationFiled: October 8, 2024Publication date: April 17, 2025Applicant: Industrial Technology Research InstituteInventor: Ching-Wen Cheng
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Publication number: 20250122129Abstract: A method for preparing an adjustable organic fertilizer is provided. The method includes providing a ratio of nitrogen, phosphorus, and potassium required for a target crop and collecting a plurality of wastes. The method includes categorizing the fertilizer concentrations of the same type of feeding substrates within the wastes separately, and adjusting the composition of the categorized wastes to form a composite feeding substrate according to the ratio of nitrogen, phosphorus, and potassium required for the target crop. The method includes subjecting the composite feeding substrate to an anaerobic fermentation process. The anaerobic fermentation process includes introducing the composite feeding substrate into an acidification tank to obtain a first mixture and introducing the first mixture into a methanogenesis tank to obtain a second mixture.Type: ApplicationFiled: October 15, 2024Publication date: April 17, 2025Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Hsin-Ju HSIEH, Laurensia IRMAYANI, Jia-Jun TEE, Shing-Der CHEN, Ren-Yang HORNG, Jer-Young CHEN, Wen-Pin HUNG
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Publication number: 20250124318Abstract: Disclosed herein are a method for decomposing a Mixed Polarity Multiple Controlled Toffoli (MPMCT) gate in a quantum circuit and a quantum circuit designed using the method. The method includes dividing a process of decomposing an MPMCT gate in a quantum circuit into a front step, a central step, and a back step, selecting one of multiple decomposition methods in consideration of the sub-MCT gate assigned to each of the steps and the number (k) of work qubits of which the initial states are known (Clean Work Qubits (CWQs)), and decomposing the MPMCT gate into gates of a Clifford+T set, which is a standard fault-tolerant gate set, by applying the selected decomposition method.Type: ApplicationFiled: April 5, 2024Publication date: April 17, 2025Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventor: Jong-Heon LEE
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Publication number: 20250120372Abstract: The present disclosure provides, in some aspects, a humanized immunodeficient mouse model of human fibrosis. A humanized immunodeficient mouse model provided herein may be used, for example, for modeling human fibrosis, predicting human fibrosis, and testing putative fibrosis treatments.Type: ApplicationFiled: December 16, 2022Publication date: April 17, 2025Applicants: The Jackson Laboratory, University of Massachusetts, Massachusetts Institute of TechnologyInventors: Leonard D. Shultz, Michael A. Brehm, Dale L. Greiner, Daniel Anderson, Joshua C. Doloff
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Publication number: 20250121433Abstract: The present disclosure discloses an oscillating-pressure-and-spark-plasma combined sintering equipment and sintering method. By providing a system comprising a mainframe structural system, a servo motor hydraulic system, an oscillating pressurized hydraulic system, a vacuum and inert gas supply system, a pulse plasma power control system, and a mainframe control system, the mainframe structure adopts a pre-tightened frame beam to ensure the strength of the system under oscillation pressure and the stability of the overall structure. The equipment is additionally provided with an oscillation hydraulic system with adjustable frequency and pressure. During the sintering process of workpieces, the oscillation pressure can achieve the slip rearrangement of particles. It adopts an overlay mode of dual hydraulic systems. Therefore, the accuracy of pressure control in the system is ensured.Type: ApplicationFiled: December 27, 2023Publication date: April 17, 2025Applicants: Precision Industry Revolution Equipment Technology (Henan) Co., Ltd., ZHENGZHOU RESEARCH INSTITUTE FOR ABRASIVES & GRINDING CO., LTD.Inventors: Jiong ZHAO, Ning YAN, Jun WEI, Yanjun ZHAO, Jianfeng CAO, Xiangxu MENG, Ruifeng HAN, Yang ZHANG, Xiaolei WU, Ying XIA
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Publication number: 20250124285Abstract: A method implemented by a software for a multimodal evaluation engine stored on a memory is provided herein. The software is executable by a processor coupled to the memory to cause the method. The method includes receiving multimodal signatures of an object of interest from inspection elements and processing the multimodal signatures to transform the multimodal signatures into formats. The method also includes generating data representations of the formats and detecting whether anomalies are present within the object of interest based on the data representations.Type: ApplicationFiled: December 20, 2024Publication date: April 17, 2025Applicant: Battelle Memorial InstituteInventors: Anthony George, Nicholas Darby, Jeremy Bellay, David Collins, Katie Liszewski, Amir Rahimi
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Publication number: 20250120643Abstract: Some aspects of the present disclosure are related to articles for measuring electrical signals internal to a subject, e.g., of the gastrointestinal tract (GI tract). The articles, in some embodiments, are ingestible and/or implantable. In some embodiments, the articles comprise a substrate comprising a plurality of electrodes, the substrate having a Young's elastic modulus of greater than or equal to 0.01 MPa and less than or equal to 200 MPa. In some such cases, the Young's elastic modulus of the substrate facilitates elastic recoil of the substrate such that at least a portion of the plurality of electrodes contact a surface of a tissue at the location internal to the subject (e.g., the GI tract) and thus facilitate measurement of electrical signals at the location internal to the subject. Other aspects are related to methods of using the articles, for example, to monitor electrical signals from the location internal to the subject.Type: ApplicationFiled: October 11, 2024Publication date: April 17, 2025Applicants: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.Inventors: Robert S. Langer, Carlo Giovanni Traverso, Siheng You, So-Yoon Yang, Adam Gierlach, George Selsing