Abstract: The computing device trains a first model on a first data set using a first graph to predict relevant links between a plurality of nodes. The computing device obtains the first data set or a second data set associated with the plurality of nodes. The computing device determines the one or more features for the one or more links between the plurality of nodes, applies the trained first model to the one or more links between the plurality of nodes, outputs the relevant links and non-relevant links of the one or more links between the plurality of nodes, removes the non-relevant links between the plurality of nodes, connects each node of the plurality of nodes with the relevant links to generate one or more first sets of networks, and outputs the one or more first sets of generated networks.
Type:
Grant
Filed:
July 25, 2024
Date of Patent:
April 22, 2025
Assignee:
SAS INSTITUTE INC.
Inventors:
Nicholas Akbar Ablitt, James Byron Morris
Abstract: A thermal management system includes a refrigerant system and a coolant system. The refrigerant system includes a compressor, an indoor heat exchanger, a first flow regulating device, a first heat exchanger and an outdoor heat exchanger. The outdoor heat exchanger includes a first port and a second port. The first flow regulating device has a bi-directional throttling function. The first heat exchanger includes a first heat exchange section and a second heat exchange section. The thermal management system has a heating mode and a cooling mode which can be achieved by the same first flow regulating device. A control method of the thermal management system is also disclosed.
Type:
Grant
Filed:
May 28, 2021
Date of Patent:
April 22, 2025
Assignee:
HANGZHOU SANHUA RESEARCH INSTITUTE CO., LTD.
Abstract: Provided are a device for measuring the amount of snowfall and a method of controlling the same, the device including a bottom plate, a graduated ruler extending upward from the bottom plate, an image capturing unit configured to capture an image of the graduated ruler and an upper portion of snow deposited on the bottom plate by using an image capturing device, a measurement unit configured to measure the amount of snowfall based on information on the captured image, and a snow removing unit configured to push out the deposited snow to the outside of the bottom plate while moving in a direction from one side to the other side of the bottom plate.
Type:
Grant
Filed:
September 26, 2022
Date of Patent:
April 22, 2025
Assignee:
NATIONAL INSTITUTE OF METEOROLOGICAL SCIENCES
Abstract: A differential proportional temperature measurement circuit and method based on bidirectional constant voltage drive is proposed. The circuit and method applied to the precision temperature measurement of spacecraft, the main components include a bidirectional constant voltage source proportional bridge circuit, a differential and single-ended amplifier circuit, an analog-to-digital conversion circuit, a digital filter circuit, a data processing circuit and an isolated filter power supply circuit. The method adopts the bidirectional constant voltage drive technology, and enlarges and measures the difference between the voltage values of the reference resistor and the resistance to be measured by improving the sensing bridge of the ordinary commutation proportional method, and suppresses the long-term drift of the excitation unit and the voltage measurement unit. The method can meet the requirements of temperature measurement resolution of ?K magnitude and the power spectral density of ?K/Hz1/2 (0.
Type:
Grant
Filed:
November 11, 2024
Date of Patent:
April 22, 2025
Assignee:
Harbin Institute of Technology
Inventors:
Hongxing Yang, Shiyuan Lin, Ziqi Yin, Yan Wang, Pengcheng Hu, Ruitao Yang
Abstract: Optically computed phase imaging systems and methods are provided. An example system includes an interferometer configured to output 3D spatial-spectral data of a sample including an interferometric signal and an optical computation assembly having a spatial light modulator configured to modulate the 3D spatial-spectral data with a modulation pattern. The modulation pattern modulates the interferometric signal along a spectral dimension to select a depth to obtain a sample signal at the selected depth and modulates the interferometric signal along a first spatial dimension to create a waveform to facilitate phase extraction. The system further includes a detector configured to detect 2D spatial data of the sample. The system further includes a processor coupled to a memory, the processor configured to process the 2D spatial data to extract phase information of the sample.
Type:
Grant
Filed:
November 10, 2022
Date of Patent:
April 22, 2025
Assignee:
New Jersey Institute of Technology
Inventors:
Xuan Liu, Yuwei Liu, Yuanwei Zhang, Zhaoxiong Wan
Abstract: Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids or the modification of nucleic acids or proteins, including editing a single site within the genome of a cell or subject, e.g., within the human genome. In some embodiments, fusion proteins of nucleic acid programmable DNA binding proteins e.g., GeoCas9 or variants thereof, and effector domains, e.g., deaminase domains, are provided. In some embodiments, methods for targeted nucleic acid editing or protein modification are provided. In some embodiments, reagents and kits for the generation of targeted nucleic acid editing proteins, e.g., fusion proteins of a GeoCas9 and effector domains, are provided.
Type:
Grant
Filed:
October 29, 2019
Date of Patent:
April 22, 2025
Assignees:
The Broad Institute, Inc., President and Fellows of Harvard College
Abstract: Provided is a method performed by a system for distribution storage of blockchain transaction data based on an erasure code. The method includes performing RS encoding on a predetermined number of blockchain transaction original data; and after the RS encoding is performed, applying LRC encoding technique to blockchain transaction original data (LRC-encoded original data), which needs to be accessed high speed, among the RS-encoded transaction original data to encode and store the LRC-encoded original data, and repairing the LRC-encoded original data through decoding.
Type:
Grant
Filed:
December 27, 2023
Date of Patent:
April 22, 2025
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Sohyun Park, Myungcheol Lee, Beongjun Choi
Abstract: Fissile target materials are provided. The fissile target materials can include a target substrate and a capturing layer operably interfacing with at least one surface of the target substrate. Fission fissile target materials are also provided that can include a target substrate comprising at least one fissile atom and a capturing layer operably interfacing with at least one surface of the target substrate. The capturing layer can include at least one fission product.
Type:
Grant
Filed:
July 31, 2020
Date of Patent:
April 22, 2025
Assignee:
Battelle Memorial Institute
Inventors:
Samuel S. Morrison, Lance R. Hubbard, Nicolas Uhnak, Bruce K. McNamara, Gabriel B. Hall
Abstract: An agricultural composition comprises living microorganisms encapsulated in polymer gel microbeads which are applied onto seeds. In another embodiment, an agricultural composition comprises living microorganisms encapsulated in polymer gel macroheads for planting with seeds in soil. In another embodiment, an agricultural composition comprises living microorganisms immobilized in a polymer gel matrix that is coated on a seed.
Type:
Grant
Filed:
November 21, 2016
Date of Patent:
April 22, 2025
Assignee:
Battelle Memorial Institute
Inventors:
Anthony D. Duong, Ramanathan S. Lalgudi, Jane P. Fife, Craig M. Bartling, Katarzyna Kucharzyk
Abstract: This invention relates to methods comprising administering a FAK inhibitor (e.g., VS-6063) in combination with a dual RAF/MEK inhibitor (e.g., CHS 126766) that are useful in the treatment of abnormal cell growth, such as cancer, in a subject such as humans.
Type:
Grant
Filed:
January 18, 2024
Date of Patent:
April 22, 2025
Assignee:
The Institute of Cancer Research: Royal Cancer Hospital
Abstract: Embodiments of the present disclosure disclose a random access method and a random access device, and relate to the field of communication technology. The method includes: first random access message is sent to a network device by a spatial terminal, where the first random access message carries a first preamble sequence, the first preamble sequence is generated based on a target mask, and the target mask is associated with a height where the spatial terminal is located; and a response message from the network device is received. In this way, the spatial terminal may initiate the random access using the first preamble sequence associated with the height where the spatial terminal is located, thereby avoiding collision and conflict with preamble sequences used by the spatial terminals at other heights, improving success rate of random access of the spatial terminal, and further improving efficiency of the random access.
Type:
Grant
Filed:
October 30, 2024
Date of Patent:
April 22, 2025
Assignee:
SHANGHAI SATELLITE NETWORK RESEARCH INSTITUTE CO., LTD.
Inventors:
Xiaofan Xu, Yueyue Zhang, Jianfei Tong, Hong Yan
Abstract: Provided are an apparatus and method for honeycomb artifacts removal for removing honeycomb artifacts in images received from an optical fiber imaging device through a honeycomb artifact removal model. The honeycomb artifact removal apparatus according to an embodiment includes a control unit configured to create a training dataset, build the honeycomb artifact removal model with the created training data, remove a honeycomb artifact in an input image through the built honeycomb artifact removal model and output a corrected image, wherein the control unit is configured to perform preprocessing of a raw image, acquire a honeycomb artifact image through the optical fiber imaging device, and synthesize the preprocessed raw image with the honeycomb artifact image to generate a honeycomb artifact synthesized image, and the training dataset is created by mapping the honeycomb artifact synthesized image as input data and the preprocessed raw image as output data.
Type:
Grant
Filed:
May 11, 2022
Date of Patent:
April 22, 2025
Assignee:
Korea Institute of Science and Technology
Abstract: A method and an apparatus for manufacturing a silicon carbide single crystal, and a silicon carbide single crystal ingot, obtaining a silicon carbide single crystal reduced in defects such as threading dislocations, are provided. The method manufactures a silicon carbide single crystal by supplying a raw material gas into a reaction vessel with a seed substrate, and heats the interior to grow a silicon carbide single crystal on the surface of the seed substrate. The method includes growing the silicon carbide single crystal on the seed substrate surface, while controlling the temperature, to perform pair annihilation of threading dislocations or synthesis of the threading dislocations; and a second step of maintaining the temperature inside the reaction vessel in the state of the first predetermined temperature after execution of the first step, to bring the leading ends of the threading dislocations close to the surface of the seed substrate.
Type:
Grant
Filed:
October 12, 2021
Date of Patent:
April 22, 2025
Assignees:
CENTRAL RESEARCH INSTITUTE OF ELECTRIC POWER INDUSTRY, DENSO CORPORATION
Abstract: The present invention relates to a substrate for nucleic acid amplification, and a method for manufacturing same, the substrate for rapid and accurate PCR analysis comprising: a transparent substrate; a metal layer formed on the transparent substrate; an N-heterocyclic carbene compound having one end annealed to the surface of the metal layer; and a primer immobilized on the other end of the N-heterocyclic carbene compound.
Type:
Grant
Filed:
July 12, 2019
Date of Patent:
April 22, 2025
Assignee:
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
Inventors:
Oh Seok Kwon, Tai Hwan Ha, Kyung Ho Kim, Jin Yeong Kim, Seon Joo Park, Seong Eun Seo
Abstract: Methods, systems, and compositions related to the recycling and/or recovery of activating materials from activated aluminum are disclosed. In one embodiment, an aqueous solution's composition may be controlled to maintain aluminum ions dissolved in solution during reaction of an activated aluminum. In another embodiment, aluminum hydroxide containing the activating materials may be dissolved into an aqueous solution to isolate the activating materials.
Type:
Grant
Filed:
February 14, 2024
Date of Patent:
April 22, 2025
Assignee:
Massachusetts Institute of Technology
Inventors:
Jude Kelley, Eric Morgan, Roderick Russell Kunz
Abstract: Provided herein are analogs of unnatural nucleotides bearing predominantly hydrophobic nucleobase analogs that form unnatural base pairs during DNA polymerase-mediated replication of DNA or RNA polymerase-mediated transcription of RNA. In this manner, the unnatural nucleobases can be introduced in a site-specific way into oligonucleotides (single or double stranded DNA or RNA), where they can provide for site-specific cleavage, or can provide a reactive linker than can undergo functionalization with a cargo-bearing reagent by means of reaction with a primary amino group or by means of click chemistry with an alkyne group of the unnatural nucleobase linker.
Type:
Grant
Filed:
February 22, 2023
Date of Patent:
April 22, 2025
Assignee:
The Scripps Research Institute
Inventors:
Floyd E. Romesberg, Denis A. Malyshev, Lingjun Li, Thomas Lavergne, Zhengtao Li
Abstract: A device includes, in part, an antenna adapted to receive an RF signal that includes modulated data, a splitter/coupler adapted to split the received RF signal, a receiver adapted to demodulate the data from a first portion of the RF signal, and a power recovery unit adapted to convert to a DC power a second portion of the RF signal. The splitter/coupler is optionally adjustable to split the RF signal in accordance with a value that may be representative of a number of factors, such as the target data rate, the DC power requirement of the device, and the like. The device optionally includes a switch and/or a power combiner adapted to deliver all the received RF power to the receiver depending on any number of operation conditions of the device or the device's distance from an RF transmitting device.
Type:
Grant
Filed:
January 4, 2023
Date of Patent:
April 22, 2025
Assignee:
California Institute of Technology
Inventors:
Seyed Ali Hajimiri, Florian Bohn, Behrooz Abiri
Abstract: A method for directly preparing a trivalent chromium compound by electrochemical oxidation of ferrochrome is provided. The method includes: putting ferrochrome as an anode, and placing the anode into an electrolyte solution containing a complexing agent together with a cathode, then turning on a power supply for electrolysis reaction so that chromium and iron in ferrochrome are directly converted into free Cr3+ and Fe3+ respectively, allowing one of Cr3+ and fe3+ to form a stable soluble metal complex together with the complexing agent, and allowing the other of Cr3+ and Fe3+ to form a metal hydroxide solid together with OH? generated by electrolysis reaction, so as to obtain an electrolysis completion slurry. Compared with the prior art, the present application has no hexavalent chromium salt stage, thereby shortening the process flow and avoiding the generation of chromium-containing waste residue.
Type:
Grant
Filed:
April 23, 2023
Date of Patent:
April 22, 2025
Assignee:
QINGHAI INSTITUTE OF SALT LAKES, CHINESE ACADEMY OF SCIENCES
Inventors:
Bo Li, Haitao Feng, Yaping Dong, Zhengrong Niu, Wu Li
Abstract: A decarboxylation coupling electrocatalysis method for catalyzing an aromatic trimethyl ammonium salt and ?-nickel ketonate is provided. The method includes the following steps: step 1, adding aryl-ammonium trifluoromethyl sulfonate, ?-keto acid and sodium acetate in a molar ratio of 1:2:2 into a reaction bottle in a nitrogen atmosphere, adding an electrolyte n-Bu4NBF4, and then adding a mixed solution of acetonitrile and N,N-dimethylformamide, where a volume ratio of the acetonitrile to the N,N-dimethylformamide is 1:4; and step 2, stirring a mixture in step 1 so as to dissolve the mixture, inserting two electrodes, using a graphite electrode as a positive electrode and a nickel electrode as a negative electrode, adding water for stirring after a reaction, and conducting extraction, drying and purification to obtain an aromatic ketone compound.