Abstract: Disclosed are a heat exchange reactor and a method of manufacturing the same, and a method of manufacturing a heat exchange reactor includes: preparing lateral plates provided with a plurality of slits formed in parallel in a longitudinal direction; disposing two lateral plates to be spaced apart from each other while facing each other in a vertical direction; forming a plurality of flow path channels by inserting flow path partition plates into one or more slits of the two lateral plates in a horizontal direction; forming a plurality of flow path channels by inserting printed circuit heat exchange plates, which autonomously include one or more heat exchange flow paths therein, into one or more slits of the two lateral plates in a horizontal direction; and bonding the lateral plates, the flow path partition plates, and the printed circuit heat exchange plates.

Abstract: The present invention relates to a therapeutic method for the treatment of cancer that comprises the use of a combination of inotuzumab ozogamicin (CMC-544) and temsirolimus. The enhanced antitumor of the combination therapy is particularly useful for patient population that are recalcitrant to inotuzumab ozogamicin or temsirolimus therapy, relapse after treatment with inotuzumab ozogamicin or temsirolimus or where enhanced antitumor effect reduces toxicities associated with treatment using inotuzumab ozogamicin or temsirolimus.

Abstract: The invention provides methods of treating a meiotic kinase-associated disease, preferably the meiotic kinase HSET, by administering an inhibitor of the meiotic kinase. Preferably, the disease is associated with the presence of supernumerary centrosomes, such as cancer. Methods of inhibiting the growth of a tumor cell by contacting the cell with an inhibitor of a meiotic kinase, preferably HSET, are also provided. Screening methods for identifying inhibitors of the meiotic kinase HSET are also provided. Methods of selecting subjects for treatment with an inhibitor of a meiotic kinase, such as HSET, are also provided.

Abstract: A method for handover in a wireless communication system includes: when a received signal strength difference between a serving beam from a serving base station used for communication by a terminal and a target beam of a neighboring base station is equal to or greater than a first threshold value, and a received signal strength difference between an active beam and the target beam is equal to or greater than a second threshold value, determining a handover to the target beam; and transmitting a message to initiate the handover.

Abstract: The present invention relates to an artificial hip joint replacement system. The system includes an acetabulum portion having a cup suitable to be received by a subject's acetabular bone. The cup includes a rigid portion and an elastic portion attached to the rigid portion. Also included in the system is a ball received within the cup and in contact with the elastic portion and a femoral stem attached to the ball. The elastic portion is positioned to cause expansion and allow contraction of a space between the ball and the rigid portion of the cup so they are further apart from one another during periods of low mechanical loads.

Abstract: A magnetic sensor for sensing an external magnetic field includes first and second electrodes and first and second magnetic tunneling junctions. The first and second electrodes are disposed over a substrate; and the first and second magnetic tunneling junctions are conductively disposed between the first and second electrodes and connected in parallel between the first and second electrodes. The first and second magnetic tunneling junctions are arranged along a first easy axis of the magnetic sensor. The first magnetic tunneling junction includes a first pinned magnetization and a first free magnetization, and the second magnetic tunneling junction includes a second pinned magnetization and a second free magnetization. The first free magnetization and the second free magnetization are arranged substantially in parallel to the first easy axis and in substantially opposite directions.

Abstract: The present invention discloses an overheat prevention energy storage system preventing self from overheating, comprising a heat dissipating external surface, wherein at least a portion of the external surface is coated with at least one layer of heat dissipation coating of high emissivity. The present invention further discloses a method for preventing overheat of the energy storage system and a method for forming at least one layer of heat dissipation coating of high emissivity onto at least part of an external surface of the energy storage system or assemblies thereof.

Abstract: A method for diagnosing a biomarker using magnetic particles and quantum dots for quantitative analysis and a biomarker diagnosis kit are provided. The method for diagnosing a biomarker includes: ii) providing magnetic particles having surfaces to which a primary antibody capable of collecting a biomarker using a linker is fixed; ii) providing quantum dots having surfaces to which a secondary antibody capable of detecting the biomarker is fixed; iii) sandwich-targeting the biomarker by the magnetic particles and the quantum dots; iv) selectively separating quantum dots sandwich-targeting the biomarker among the quantum dots; and v) quantifying the concentration of the biomarker by measuring absorbance or intensity of fluorescence of separated quantum dots.

Abstract: In a method of rendering a plurality of graph elements, first sample data is generated to render an instance of a first graph element type in a first cell of a canvas panel. An indicator is received that indicates a second graph element type to present in the first cell overlaid with the instance of the first graph element type. Second sample data is generated to render an instance of the second graph element type in the first cell overlaid with the instance of the first graph element type. An indicator is received that indicates selection of a fourth indicator of the instance of the second graph element type. An indicator is received that indicates dropping of the fourth indicator into a second cell. Third sample data is generated to render a second instance of the second graph element type in the second cell.

Abstract: Electrochemical experiments are performed on a collection of samples by suspending a drop of electrolyte solution between an electrochemical experiment probe and one of the samples that serves as a test sample. During the electrochemical experiment, the electrolyte solution is added to the drop and an output solution is removed from the drop. The probe and collection of samples can be moved relative to one another so the probe can be scanned across the samples.

Abstract: There has been a need for coelenterazine analogs that exhibit luminescence properties different from those of known coelenterazine analogs. The present invention provides the compound represented by general formula (1).

Abstract: Provided is an electrolyte additive for a lithium ion secondary battery including an organic lithium compound and a hyper-branched structure material. The electrolyte additive enhances the decomposition voltage of the electrolyte up to 5.5 V, and increases the heat endurable temperature by 10° C. or more. The safety of the battery is thus improved.

Abstract: For an ultra dense network (UDN) having small cells of highly overlapped coverages, a user equipment (UE) selects in a handover process a preferred base station (BS) from candidate BSs for minimizing occurrence of handover events. The UE computes finite differences consisting of a first-, a second-, and one or more higher-order differences, according to received signal strength (RSS) values obtained for each candidate BS. A preference level, which is a total number of finite differences having consecutive order numbers, including the first-order difference, and being positive or non-negative, is computed for each candidate BS. One or more favorable candidate BSs from the candidate BSs are identified such that the group of such favorable candidate BSs has the same preference level that is maximum among all the preference levels computed for the candidate BSs. The preferred BS is selected from the group of such favorable candidate BSs.

Abstract: The invention provides a method and device of extracting a sound source acoustic image body in 3D space. The method includes: determining a spatial position of a sound source acoustic image and determining a speaker beside the spatial position where the sound source acoustic image is located according to the determined spatial position (?, ?, ?) of the sound source acoustic image; calculating a correlation of signals of all sound tracks of the selected speaker in the horizontal direction and the vertical direction, and obtaining and storing a parameter set {ICH, ICv, Min{ICH, ICv}} of a acoustic image body, wherein the Min{ICH, ICv} is a smaller value between ICH and ICV. The expression parameters of the acoustic image body obtained in the present invention are used for providing technical support for accurately restoring the size of the sound source acoustic image in a 3D audio live system, which solves the technical problem that the restored acoustic image in a 3D audio is excessively narrow at present.

Abstract: A byte addressable storing system is provided. The byte addressable storing system includes a data transmission interface and a processing unit. The data transmission interface connects to a byte addressable storing device. The processing unit creates a primary metadata table, a secondary metadata table, an indirect metadata matching table, a sub-block using status table and a metadata pointer in the byte addressable storing device via the data transmission interface. The processing unit further adjusts the allocation of metadata in the byte addressable storing device dynamically based on the aforesaid tables and pointer. The processing unit further stores a file into sub-blocks of blocks non-sequentially, and achieves record of the file via dynamic multi-level pointing.

Abstract: An e-Petri dish comprising a transparent layer having a specimen surface and a light detector configured to sample a sequence of sub-pixel shifted projection images of a specimen located on the specimen surface. The sub-pixel shifted projection images associated with light from a plurality of illumination angles provided by an illumination source.

Abstract: The treatment options for treating blast-induced and noise-induced traumatic brain injury and tinnitus are limited. Thus, the current invention provides methods for treating traumatic brain injury and tinnitus. The methods involve administering a pharmaceutically effective amount of a composition comprising 2,4-disulfonyl ?-phenyl tertiary butyl nitrone and N-acetylcysteine (NAC).

Abstract: A wound care dressing is provided, including a hydrophobic base fabric, a plurality of electrode pairs, a plurality of hydrogel layers, and a waterproof thin film. The hydrophobic base fabric has a first surface and a second surface opposite to each other. The electrode pairs are arranged in an array and disposed on the first surface of the hydrophobic base fabric. The hydrogel layers are not in contact with one other, and each hydrogel layer covers a top surface and side walls of each electrode in the electrode pairs. After the hydrogel layers are in contact with a wound and absorb tissue fluid from the wound, the hydrogel layers form a restrictive electronic cycling channel with the electrode pairs to establish a plurality of bioelectric fields promoting wound healing on a surface of the wound. The waterproof thin film is disposed on the second surface of the hydrophobic base fabric.

Abstract: A method and apparatus for detecting an isotope. Embodiments can detect radioactive isotopes. Embodiments can utilize a detector that incorporates at least two sub-detectors. Each sub-detector can receive energy from an isotope and create a signal corresponding to the received energy. Each sub-detector can incorporate a detector element, such as a detector element incorporating one or more diodes, a detector element incorporating a crystal, a detector element incorporating a solid-state device, or a detector element incorporating a scintillator. The sub-detectors can be configured such that for each isotope to be detected at least two of the sub-detectors produce different output signals, or readings. In an embodiment, each sub-detector is configured such that when there are at least two sub-detectors exposed to the isotope each of the corresponding readings from the sub-detectors is different from each of the other readings.

Abstract: A general-purpose vehicle remote control device and method are disclosed. The general-purpose vehicle remote control device includes a network communication unit, a user authentication unit, a user information database, and a remote control unit. The network communication unit communicates with a user who accesses a general-purpose vehicle remote control device over a network. The user authentication unit identifies the user. The user information database stores user information required for the identification of the user. The remote control unit transceives control signals and state information with a vehicle of the identified user or remotely starts the vehicle.