Abstract: Embodiments of the invention provide a method detecting and treating cancer, such as lung cancer. In some aspects, the method may include detecting cancer in a subject, which may comprise assessing the expression of a marker in a sample from the subject. For example, the marker may comprise c-Met and/or Fn14. In some embodiments, if the subject is diagnosed as having cancer, the method may further provide administering a therapeutically effective amount of a substance that reduces the expression level of Fn14 to the subject to reduce the invasive and migratory capabilities of the cancer.

Abstract: Purine scaffold Hsp90 inhibitors are useful in therapeutic applications and as radioimaging ligands.

Abstract: The present invention provides a spin-transfer torque type injection locking oscillator which improves both power and noise performance by using pair of spin-transfer torque devices. One is optimized for high power and the other is optimized for low noise characteristics. The output signal of the low noise spin-transfer torque device is injected into the high output power spin-transfer torque for phase locking. The present invention has several advantages such as the miniaturization, the high quality and low cost, and the mass production of integrated chips by the nanoscale.

Abstract: Fluid-based no-moving part logic devices are constructed from complex sequences of micro- and nanofluidic channels, on-demand bubble/droplet modulators and generators for programming the devices, and micro- and nanofluidic droplet/bubble memory elements for storage and retrieval of biological or chemical elements. The input sequence of bubbles/droplets encodes information, with the output being another sequence of bubbles/droplets or on-chip chemical synthesis. For performing a set of reactions/tasks or process control, the modulators can be used to program the device by producing a precisely timed sequence of bubbles/droplets, resulting in a cascade of logic operations within the micro- or nanofluidic channel sequence, utilizing the generated droplets/bubbles as a control. The devices are based on the principle of minimum energy interfaces formed between the two fluid phases enclosed inside precise channel geometries.

Abstract: The present disclosure provides a method for producing carbon nanoparticles at low cost and with good efficiency. According to the disclosure of the present description, a voltage is applied between a graphite positive electrode and a negative electrode in an aqueous medium to generate arc discharge in a gap. An inert gas is introduced into the gap from a cylinder bottle at a predetermined flow rate. In this manner, carbon nanoparticles can be produced from carbon steam that is generated in the gap as a result of the arc discharge.

Abstract: A system and method for monitoring the properties of a fluid, such as water, in a steam pipe without mechanically penetrating the wall of the pipe. The system uses a piezoelectric transducer to launch an ultrasonic probe signal into the pipe. Reflected ultrasonic signals are captured in a transducer, which can be the same transducer that launched the probe signal. The reflected signals are subjected to data processing, which can include filtering, amplification, analog-to-digital conversion and autocorrelation analysis. A result is extracted which is indicative of a property of the fluid, such as a height of the condensed fluid, a cavitation of the condensed fluid, and a surface perturbation of the condensed fluid. The result can be recorded, displayed, and/or transmitted to another location. One embodiment of the system has been constructed and tested based on a general purpose programmable computer using instructions recorded in machine-readable non-volatile memory.

Abstract: Techniques are generally described for a progressive cavity pump and methods for making and using a progressive cavity pump. In an example, a progressive cavity pump may include a stator, a rotor and/or a bearing. The stator may include a helical shaped interior with a first pitch. The rotor may be inside the stator. The rotor may include a helical shaped exterior with a second pitch. The second pitch may be different from the first pitch. The rotor may be effective to rotate with respect to the stator and effective to move eccentrically within the stator to define at least one cavity inside the stator. At least one bearing may be between the rotor and the stator. The bearing may be sized and shaped so that the rotor is effective to rotate inside the bearing and the bearing is effective to move eccentrically along with the rotor.

Abstract: This invention relates to methods for selecting a treatment, treating, and predicting survival time in subjects with cancer, such as colorectal cancer, based on tumor expression levels of chemokines, cytotoxic genes, and/or dendritic cell genes.

Abstract: Disclosed are a magnetic field-controlled movable bio-scaffold and a method for constructing the same. The bio-scaffold is highly biocompatible and can readily move to a target site under the control of an external magnetic field.

Abstract: In exemplary implementations of this invention, light from a light field projector is transmitted through an angle-expanding screen to create a glasses-free, 3D display. The display can be horizontal-only parallax or full parallax. In the former case, a vertical diffuser may positioned in the optical stack. The angle-expanding screen may comprise two planar arrays of optical elements (e.g., lenslets or lenticules) separated from each other by the sum of their focal distances. Alternatively, a light field projector may project light rays through a focusing lens onto a diffuse, transmissive screen. In this alternative approach, the light field projector may comprise two spatial light modulators (SLMs). A focused image of the first SLM, and a slightly blurred image of the second SLM, are optically combined on the diffuser, creating a combined image that has a higher spatial resolution and a higher dynamic range than either of two SLMs.

Abstract: A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid compound or derivative thereof, wherein the compound or derivative thereof is able to readily enter the mitochondrion without special transport enzymes. A dietary formulation suitable for treatment of heart tissue in cardiac or surgical patients has been found which comprises a seven-carbon fatty acid chain, wherein the seven-carbon fatty acid chain is characterized by the ability to transverse the inner mitochondrial membrane by a transport mechanism which does not require carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, or carnitine/acylcarnitine translocase and the ability to undergo mitochondrial ?-oxidation, and wherein the compound is selected from the group consisting of n-heptanoic acid or a derivative thereof, a triglyceride comprising n-heptanoic acid or a derivative thereof, and triheptanoin or a derivative thereof.

Abstract: According to embodiments of the disclosure, a flexible device and a fabrication method thereof are provided. The flexible device has a first area and a second area, and the stiffness of a portion of the first area is greater than the stiffness of the second area. The flexible device may include a flexible substrate and a rigid element. The flexible substrate includes a first surface and a second surface opposite to each other. The second surface has a coarse structure. The surface roughness of the second surface is greater in the first area than in the second area. The rigid element is disposed on the first surface of the flexible substrate and located in the first area. The stiffness of the rigid element is greater than the stiffness of the flexible substrate. A projection area of the coarse structure on the flexible substrate overlaps an area of the rigid element.

Abstract: Improved lithium-sulfur energy storage systems can utilizes LixSy as a component in an electrode of the system. For example, the energy storage system can include a first electrode current collector, a second electrode current collector, and an ion-permeable separator separating the first and second electrode current collectors. A second electrode is arranged between the second electrode current collector and the separator. A first electrode is arranged between the first electrode current collector and the separator and comprises a first condensed-phase fluid comprising LixSy. The energy storage system can be arranged such that the first electrode functions as a positive or a negative electrode.

Abstract: A live biological specimen is imaged by generating a plurality of light sheets; directing the plurality of light sheets along an illumination axis through the biological specimen such that the light sheets spatially and temporally overlap within the biological specimen along an image plane, and optically interact with the biological specimen within the image plane; and recording, at each of a plurality of views, images of the fluorescence emitted along a detection axis from the biological specimen due to the optical interaction between the light sheets and the biological specimen. The temporal overlap is within a time shift that is less than a resolution time that corresponds to a spatial resolution limit of the microscope.

Abstract: A terminal device (1) frame-length-modulates an identifier of the radio apparatus (3) to generate a plurality of frames having a plurality of frame lengths, and transmits the generated plurality of frames to an access point (2) over wire or wireless communication. The access point (2) transfers the plurality of frames transmitted by the terminal device (1) to the radio apparatus (3) in the IP or MAC layer. The radio apparatus (3) detects the plurality of frame lengths of the plurality of frames received from the access point (2) and decodes the detected plurality of frame lengths to obtain an identifier. If the obtained identifier matches the identifier of the radio apparatus (3), the radio apparatus (3) transitions to active mode.

Abstract: Neutron-detecting structures and methods of fabrication are provided which include: a substrate with a plurality of cavities extending into the substrate from a surface; a p-n junction within the substrate and extending, at least in part, in spaced opposing relation to inner cavity walls of the substrate defining the plurality of cavities; and a neutron-responsive material disposed within the plurality of cavities. The neutron-responsive material is responsive to neutrons absorbed for releasing ionization radiation products, and the p-n junction within the substrate spaced in opposing relation to and extending, at least in part, along the inner cavity walls of the substrate reduces leakage current of the neutron-detecting structure.

Abstract: The present invention generally relates to compositions, methods, and systems for separating carbon-based nanostructures.

Abstract: The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids.

Abstract: An automated adaptive optics and laser projection system is described. The automated adaptive optics and laser projection system includes an adaptive optics system and a compact laser projection system with related laser guidance programming used to correct atmospheric distortion induced on light received by a telescope. Control of the automated adaptive optics and laser projection system is designed in a modular manner in order to facilitate replication of the system to be used with a variety of different telescopes. Related methods are also described.

Abstract: The present disclosure provides, in part, compositions comprising an antibody or antibody fragment that immunospecifically binds to MCH class I polypeptide-related sequence A (MICA), or an epitope thereof.