Abstract: The present application relates broadly neutralizing monoclonal antibodies directed against HIV-1. In particular, monoclonal antibodies VRC-PG04 and VRC-PG05 are disclosed.
Type:
Grant
Filed:
March 10, 2013
Date of Patent:
July 5, 2016
Assignees:
INTERNATIONAL AIDS VACCINE INITIATIVE, THE SCRIPPS RESEARCH INSTITUTE, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
Inventors:
John Mascola, Dennis R. Burton, Wayne Koff, Peter Kwong, Gary Nabel, Sanjay K. Phogat, Pascal Raymond Georges Poignard, Melissa Danielle De Jean St. Marcel Simek-Lemos, Xueling Wu, Tongqing Zhou, Zhi-Yong Yang
Abstract: A terminal receives access priority information on a plurality of sub-beams configuring a beam from a base station, selects one of a plurality of beams, and selects one of a plurality of sub-beams of the selected beam on the basis of the access priority information to perform a random access.
Type:
Application
Filed:
December 29, 2015
Publication date:
June 30, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: The present disclosure provides a top emitting organic electroluminescent device including a first scattering layer, and a first electrode, at least one organic material layer, a second electrode and a second scattering layer formed on the first scattering layer sequentially. The first scattering layer contains a plurality of micro-particles that are 10 to 90 wt % of the first scattering layer.
Type:
Application
Filed:
December 26, 2014
Publication date:
June 30, 2016
Applicant:
Industrial Technology Research Institute
Inventors:
Jung-Yu Liao, Tien-Shou Shieh, Pei-Ching Liu
Abstract: The present invention relates to a continuous manufacturing process for a rubber masterbatch and a rubber masterbatch prepared therefrom. The manufacturing process comprises the following steps: step 1): a filler is added to a rubber solution, forming a rubber/filler/solvent mixture by stirring; and step 2): the solvent is removed and the mixture is dried, resulting in a rubber/filler masterbatch. The present invention also relates to a masterbatch prepared by the above-mentioned process and a rubber article prepared using the masterbatch. Compared to the wet mixing technologies in the prior art, the present invention has no specific requirements of rubber and filler, with a wider scope of usage. In addition, the filler has a high dispersion in rubber compounds, the production process thereof is continuous, highly efficient, low in energy consumption and labour, and thus low in cost.
Type:
Application
Filed:
July 22, 2014
Publication date:
June 30, 2016
Applicant:
EYE RUBBER INSTITUTE CO., LTD.
Inventors:
Mengjiao Wang, Jianjun Song, Deying Dai
Abstract: The disclosure provides an apparatus for aligning first and second plates that are parallel to each other and have the same orientation. The apparatus includes a detector that detects composite small-angle X-ray scattering emitted from patterns of the first and second plates that are perpendicularly impinged by X-ray, and a moving unit that aligns the first and second plates according to a composite amplitude distribution of the composite small-angle X-ray scattering. Therefore, the first and second plates are aligned to each other accurately.
Type:
Application
Filed:
December 24, 2014
Publication date:
June 30, 2016
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: A system comprising: a solid oxide fuel cell having an anode and a cathode; an anode recycle loop; and an adiabatic steam reformer positioned in the anode recycle loop.
Abstract: It has been very difficult to accumulate strong laser in the conventional optical resonator, because firstly it has been very difficult to control a resonator length less than 1 ? in resonation position which is required for the laser amplification more than 1,000 times and secondly, the conventional method has utilized laser strength of amplified laser in the optical resonator as the resonance control signal. The present invention provides an optical resonator system to accumulate strong laser. In the system, unamplified modulation wave or harmonic which are derived from oscillation laser are selectively used to tune a resonator length of the optical resonator.
Type:
Application
Filed:
September 12, 2013
Publication date:
June 30, 2016
Applicant:
Inter-University Research Institute Corporation High Energy Accelerator Research Organization
Abstract: Provided is a composition for treating diabetes, including a hypoglycemic agent and a Yukmijihwang-tang extract. More particularly, the hypoglycemic agent is administered into an individual, and the Yukmijihwang-tang extract is administered into the individual, thereby considerably increasing a hypoglycemic effect of the hypoglycemic agent, and preventing and reducing various diabetic complications such as diabetes and diabetic liver damage, renal damage, hyperlipidemia immunosuppression and ocular damage.
Type:
Application
Filed:
May 2, 2014
Publication date:
June 30, 2016
Applicant:
COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
Inventors:
Seok Bong KANG, Ho Sang SOHN, Joon Seok BYUN, Ki Cheul SOHN, Sae Kwang KU
Abstract: An apparatus and a method of manufacturing mesoporous silica are provided. The apparatus includes a mount, a reactor rotatably coupled to the mount, in which mixed solution of surfactant, water and acid is to be poured, an impeller installed to the reactor and rotating to stir the mixed solution, and a heating unit installed to cover an outer surface of the reactor thereby heating the reactor.
Type:
Application
Filed:
December 16, 2015
Publication date:
June 30, 2016
Applicant:
KOREA INSTITUTE OF CERAMIC ENGINEERING AND THCHNOLOGY
Abstract: Medical instruments, particularly structurally-adjustable speculums and retractors for obstetrical and gynecological operations, procedures, and examinations, including a minimally obstructive compact speculum or retractor. The compact speculum may comprise a first wing and a second wing; and a hinge comprising at least one hinge component. The compact speculum may further comprise a ratchet that releasably holds the wings in an open position. The hinge component may comprise the ratchet, an illumination source, a fluid handler, a light guide, a lubrication source, or a combination thereof. The compact speculum may be a vaginal speculum.
Type:
Application
Filed:
August 3, 2015
Publication date:
June 30, 2016
Applicant:
Alfred E. Mann Institute for Biomedical Engineering at the University of Southern Californ
Abstract: The present invention relates to a method of treating a warm-blooded animal, especially a human, having Mixed Lineage Leukemia (MLL rearranged ALL) comprising administering to said animal a therapeutically effective amount of a staurosporine derivative, especially PKC412 or a pharmaceutically acceptable salt thereof, alone or in combination with further therapeutic measures, for example, those defined herein; to the use of a staurosporine derivative for the preparation of a medicament for the treatment of MLL rearranged ALL; and to a commercial package comprising a staurosporine derivative together with instructions for its use in the treatment of MLL rearranged ALL.
Type:
Application
Filed:
October 30, 2015
Publication date:
June 30, 2016
Applicants:
DANA-FARBER CANCER INSTITUTE INC., NOVARTIS AG
Abstract: Disclosed is a base station apparatus and the base station apparatus includes: a first beam scheduler allocating resources to a plurality of electronic apparatuses corresponding to a first beam and generating resource allocation information including the resource allocation details; a second beam scheduler allocating resources to a plurality of electronic apparatuses corresponding to a second beam and generating resource allocation information including the resource allocation details; and a control scheduler receiving at least some of the resource allocation information generated by the first beam scheduler from the first beam scheduler, receiving at least some among the resource allocation information generated by the second beam scheduler from the second beam scheduler, and transmitting at least some information received from the second beam scheduler to the first beam scheduler, in which the first beam scheduler generates electronic apparatus control information based on at least some among the resource a
Type:
Application
Filed:
December 29, 2015
Publication date:
June 30, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: A compound, and a polymer prepared therefrom, are provided. The compound has a structure represented by Formula (I) or Formula (II): wherein A is R1 is C1-10 alkyl, C5-12 cycloalkyl, C6-14 aryl, C3-12 heteroaryl, C1-10 alkoxy, C6-12 aryloxy, C1-10 silyl, amino, thiol, or phosphonate group; R2 is H, or C1-10 alkyl; and, R3 is C1-10 alkoxy, C1-10 alkanol, amine, or hydroxy.
Type:
Application
Filed:
September 10, 2015
Publication date:
June 30, 2016
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: An ultrasound imaging system includes a beam receiving circuit and a back-end circuit. The beam receiving circuit receives a plurality of digitized echo signals. The back-end circuit is coupled to the beam receiving circuit for outputting a plurality of compressed delay timing parameters corresponding to a plurality of channels to the beam receiving circuit. The beam receiving circuit decompresses the compressed delay timing parameters into a plurality of delay timing parameters, and processes the digitized echo signals into an ultrasound beamforming value according to the delay timing parameters corresponding to the channels. The back-end circuit synthesizes an ultrasound image according to the ultrasound beamforming value outputted from the beam receiving circuit.
Type:
Application
Filed:
September 22, 2015
Publication date:
June 30, 2016
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: The disclosure provides a method for producing extracellular proteins from genus Tepidimonas, including: performing a fermentation culturing to a bacteria of genus Tepidimonas with a culturing medium to form a fermented liquid, wherein the composition of the culturing medium includes a carbon source which is an organic acid, selected from a group consisting of acetate, lactate and butyrate; a nitrogen source selected from a group consisting of (NH4)2SO4, NH4NO3, NH4Cl and urea; phosphate; carbonate; MgCl2; yeast extract; and trace elements, and wherein the gas feeding rate for the fermentation culturing is about 0-0.1 vvm; and after the fermentation culturing is completed, collecting the fermented liquid, wherein the fermented liquid contains extracellular protein secreted from the bacteria of genus Tepidimonas.
Type:
Application
Filed:
August 28, 2015
Publication date:
June 30, 2016
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: Systems and methods for classifying abnormalities within optical coherence tomography images of the eye are presented. One embodiment of the present invention is the classification of pigment epithelial detachments (PEDs) based on characteristics of their internal reflectivity, size and shape. The classification can be based on selected subsets of the data located within or surrounding the abnormalities. Training data can be used to generate the classification scheme and the classification can be weighted to highlight specific classes of particular clinical interest.
Type:
Application
Filed:
December 7, 2015
Publication date:
June 30, 2016
Applicant:
Doheny Eye Institute -University of Southern California
Abstract: Disclosed herein is a device-to-device discovery method in a wireless communication system. A device determines whether a first subframe for a physical layer uplink channel or signal and a second subframe for the discovery signal are the same. The device transmits the physical layer uplink channel or signal without transmitting or receiving the discovery signal, in the same subframe, when the first subframe and the second subframe are the same.
Type:
Application
Filed:
August 6, 2014
Publication date:
June 30, 2016
Applicant:
Electronics and Telecommunications Research Institute
Abstract: The present invention is directed to methods, compositions and reaction mixtures for conducting COLD-PCR, by controlling and varying a preferential denaturation time.