Patents Assigned to INSTITUTE
  • Publication number: 20160045514
    Abstract: Described herein are compounds and compositions for the amelioration of arthritis or joint injuries by inducing mesenchymal stem cells into chondrocytes.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 18, 2016
    Applicant: The California Institute for Biomedical Research
    Inventors: Peter G. SCHULTZ, Arnab K. CHATTERJEE, Shoutian ZHU, Joshua PAYETTE, Hongchul YOON, Baiyuan YANG
  • Publication number: 20160046885
    Abstract: Embodiments of branched polymer lubricant additives comprise a branched polymer and, when combined with a lubricant base at a concentration from 1 wt % to 50 wt %, provide (i) a viscosity index ?150, (ii) that is at least 10% less than a coefficient of friction of the lubricant base alone in contact with a component of a device during operation of the device at a temperature within a range of 20 to 100° C., or (iii) both (i) and (ii).
    Type: Application
    Filed: August 11, 2015
    Publication date: February 18, 2016
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: Lelia Cosimbescu, Joshua W. Robinson, Priyanka Bhattacharya
  • Publication number: 20160047809
    Abstract: The present invention provides the in-vitro use of at least one in-vivo-target antigen of Aspergillus fumigatus for selective activation, detection and/or analysis of Aspergillus fumigatus specific CD4+ T cells in a sample comprising cells, wherein said at least one in-vivo-target antigen reveals an immune reactivity characterized by i) the in vivo existence of antigen-specific T cells comprising more than 60% memory T cells and ii) said antigen-specific T cells further comprise T cells able to produce IFN-gamma upon stimulation at a frequency between 15% and 80% and/or IL17 upon stimulation at a frequency between 5% and 30%. Said at least one in-vivo-target antigen may be selected from the group consisting of antigens Scw4, Pst1, Shm2, GliT and TpiA or fragments thereof. Also provided are a method, a composition, and a kit thereof.
    Type: Application
    Filed: August 12, 2015
    Publication date: February 18, 2016
    Applicants: MILTENYI BIOTEC GMBH, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoll Institute
    Inventors: Alexander SCHEFFOLD, Petra BACHER, Olaf KNIEMEYER, Janka TEUTSCHBEIN, Axel BRAKHAGE
  • Publication number: 20160049596
    Abstract: The present invention provides an organic thin film and an organic transistor having high performance stability and mobility. Specifically, there are provided an organic thin film including a compound containing a charge transporting molecular unit A having a structure of an aromatic fused ring system and a unit B serving as a side chain, the compound having a bilayer structure; an organic semiconductor device including the organic thin film; and an organic transistor including the organic thin film used as an organic semiconductor layer.
    Type: Application
    Filed: March 6, 2014
    Publication date: February 18, 2016
    Applicants: DIC CORPORATION, TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Junichi HANNA, Hiroaki LINO, Yasuyuki WATANABE, Junichiro KOIKE, Hiroshi MAKI, Yutaka TACHIKAWA, Atsuhisa MIYAWAKI, Yoshinobu SAKURAI
  • Publication number: 20160045149
    Abstract: [Object] An object is to provide a brain activity measuring apparatus and a brain activity measuring method that can precisely ensure reproducibility of measurements for a plurality of measurements made separately for a number of times using functional magnetic resonance imaging. [Solution] In an MRI apparatus 10, a data processing unit 32 determines rigid transformation between an original tomographic image obtained in a past measurement and stored in a storage unit 36 and a pilot tomographic image obtained in a present imaging session such that mutual information between the original and pilot tomographic images is locally maximized; and based on a parameter of the determined rigid transformation, position and direction of a slice image of the tomographic image in the present imaging session are corrected.
    Type: Application
    Filed: March 18, 2014
    Publication date: February 18, 2016
    Applicant: Advanced Telecommunications Research Institute International
    Inventors: Hironori NISHIMOTO, Takanori KOCHIYAMA, Yasuhiro SHIMADA, Ichirou FUJIMOTO
  • Patent number: 9264185
    Abstract: Provided are a packet processing apparatus and method for detecting a duplicate acknowledgement (ACK) packet. The packet processing apparatus initiates a session and then detects a retransmission packet and a duplicate ACK packet from input/output packets using statistic information related to packet retransmission. Accordingly, unnecessary traffic generated regardless of a user's intension can be blocked.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: February 16, 2016
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Dong-Won Kang, Joon-Kyung Lee, Sang-Wan Kim, Wang-Bong Lee, Sang-Sik Yoon, Jong-Dae Park
  • Patent number: 9260749
    Abstract: A method and a kit for cloning a nucleotide sequence adjacent to a known nucleotide sequence by PCR are disclosed. The method includes 1) preparing a DNA fragment with cohesive ends by cleaving a DNA that contains the known first nucleotide sequence and the second nucleotide sequence adjacent thereto using a restriction enzyme; 2) modifying the 3? end of the DNA fragment with a nucleotide analog to block further elongation of the DNA fragment; 3) linking the cohesive ends of the 3? end-modified DNA fragment with a linker, adapter or cassette having a cohesive end sequence complementary thereto; and 4) performing PCR using a known first nucleotide sequence-specific primer, and a linker, adapter or cassette sequence-specific primer.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: February 16, 2016
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Jung Hoon Sohn, Jung Hoon Bae
  • Patent number: 9261496
    Abstract: Provided herein are microfluidic devices that can be used as a 3D bioassay, e.g., for drug screening, personalized medicine, tissue engineering, wound healing, and other applications. The device has a series of channels {e.g., small fluid channels) in a small polymer block wherein one or more of the channels can be filled with a biologically relevant gel, such as collagen, which is held in place by posts. As shown herein, when the device is plated with cells such as endothelial cells, new blood vessels grow in the gel, which is thick enough for the cells to grow in three dimensions. Other channels, e.g., fluid channels, allow drugs or biological material to be exposed to the 3D cell growth. Cells, such as endothelial cells, can be cultured and observed as they grow on the surface of a 3D gel scaffold, where e.g., rates of angiogenesis can be measured, as well as intervascularization and extravascularization of cancerous cells.
    Type: Grant
    Filed: September 29, 2011
    Date of Patent: February 16, 2016
    Assignees: Massachusetts Institute of Technology, The General Hospital Corporation, The Brigham and Women's Hospital, Inc., Children's Medical Center, Corp.
    Inventors: Roger Dale Kamm, Haruhiko Harry Asada, Waleed Ahmed Farahat, Ioannis K. Zervantonakis, Levi B. Wood, Chandrasekhar Kothapalli, Seok Chung, Jeffrey D. Macklis, Suzanne Tharin, Johanna Varner, Young Kum Park, Kwang Ho Lee, Le Thanh Tu Nguyen, Choong Kim
  • Patent number: 9261119
    Abstract: For eliminating turbulence in a wall bounded flow a section of the flow-bounding wall is moved in the direction of the flow over the flow-bounding wall.
    Type: Grant
    Filed: November 22, 2011
    Date of Patent: February 16, 2016
    Assignee: INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA
    Inventor: Björn Hof
  • Patent number: 9265071
    Abstract: A signaling method for a terminal that performs direct communication between terminals terminal is disclosed. A transmitting terminal transmits a link establishment request message for establishing a link to a receiving terminal, and the receiving terminal transmits a link establishment response message responding to this message to the transmitting terminal. The link establishment request message includes a field indicating a flow to use if the receiving terminal acquires a token.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: February 16, 2016
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Sung Cheol Chang, Mi Young Yun, Seokki Kim, Won-Ik Kim, Hyun Lee, Sung Kyung Kim, Chul Sik Yoon
  • Patent number: 9259493
    Abstract: Disclosed is a liver tumor-targeting ultrasound contrast agent. The ultrasound contrast agent includes a gas-generating core and a hyaluronic acid shell. The ultrasound contrast agent can be specifically delivered to liver cells. This specific delivery enables easy differentiation between normal liver cells and liver tumor cells by ultrasound imaging. In addition, the ultrasound contrast agent is highly stable in aqueous condition and causes no cytotoxicity. Also disclosed is a method for preparing the ultrasound contrast agent.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: February 16, 2016
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kwang Meyung Kim, Ick Chan Kwon, Inchan Youn, Hyun Su Min, Hong Yeol Yoon, Jae Hyung Park
  • Patent number: 9260524
    Abstract: The invention relates to specific binding members, particularly antibodies and active fragments thereof, which recognize an aberrant post-translationally modified, particularly an aberrant glycosylated form of the EGFR. The binding members, particularly antibodies and fragments thereof, of the invention do not bind to EGFR on normal cells in the absence of amplification of the wild-type gene and are capable of binding the de2-7 EGFR at an epitope which is distinct from the junctional peptide. Antibodies of this type are exemplified by the novel antibody 806 whose VH and VL sequences are illustrated as SEQ ID NOs: 2 and 4 and chimeric antibodies thereof as exemplified by ch806.
    Type: Grant
    Filed: December 11, 2012
    Date of Patent: February 16, 2016
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Lloyd J. Old, Gerd Ritter, Achim Jungbluth, Elisabeth Stockert, Webster K. Cavenee
  • Patent number: 9261566
    Abstract: An impedance analysis device adapted to an object under test (OUT) includes a signal generator, a signal analysis unit and a processing unit. The signal generator outputs a pulse signal to the OUT. The signal analysis unit acquires a response signal which the OUT responds to the pulse signal, and analyzes the response signal to obtain an analysis parameter. The processing unit coupled to the signal analysis unit receives the analysis parameter, so as to obtain an impedance variation characteristic of the OUT.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: February 16, 2016
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Cihun-Siyong Gong, Yi-Feng Luo, Li-Ren Huang, Kai-Cheung Juang
  • Patent number: 9261578
    Abstract: An apparatus for creating a radio map includes a radio signal acquiring unit that acquires information on radio signals between one or more cooperative intelligent robots, a radio environment modeling unit that estimates radio strength for each cell configuring the radio map from the information on radio signals acquired by the radio signal acquiring unit, and a radio map creating unit that classifies a communication region of each cell and models the radio map according to the radio strength for each cell estimated by the radio environment modeling unit.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: February 16, 2016
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Hyun-Ja Im, Chang-Eun Lee, Min-Su Jang, Dae-Ha Lee, Seo-Hyun Jeon, Young-Jo Cho, Sung-Hoon Kim, Jong-Hyun Park
  • Patent number: 9259597
    Abstract: A phacoemulsificator for the removal of lens tissue, wherein the phacoemulsificator contains: a power source configured to provide pulsed electrical power, and a pump configured to provide vacuum, characterized in that the phacoemulsificator contains at least one eye ring connectable to the pump wherein the proximal end of said eye ring is suitable to be applied onto an ocular globe and means to generate ultrasound beam connectable to the power source wherein said means are fixed on the distal end of the eye ring.
    Type: Grant
    Filed: August 26, 2009
    Date of Patent: February 16, 2016
    Assignees: EYE TECH CARE, INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Fabrizio Romano, Philippe Chapuis, Laurent Farcy, Thomas Charrel
  • Patent number: 9263854
    Abstract: Technologies are generally described for implementing non-linear VCSEL equalization. In some examples, a rising edge tap parameter, a falling edge tap parameter, an equalization delay and a bias current may be used to equalize a data signal to be output from a VCSEL. A VCSEL model may be used to derive a VCSEL response to one or more isolated data pulses. The derived response may then be used to determine the rising and falling edge tap parameters and an equalization delay, based on a bias current value for the VCSEL and a data rate associated with the data signal. The data signal may then be adjusted based on the equalization delay and the rising and falling edge tap parameter and sent to the VCSEL for output. At the same time, the VCSEL may be biased with a bias current having the bias current value.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: February 16, 2016
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Mayank Raj, Azita Emami
  • Patent number: 9264174
    Abstract: A wideband intelligent jamming control apparatus and method is provided, which efficiently control an unauthorized threat signal. The wideband intelligent jamming control apparatus includes a signal detection terminal for detecting and analyzing wideband frequency signals in real time, and transmitting a jamming command and jamming signal specification information if a corresponding wideband frequency signal is determined to be an unauthorized threat signal. A jamming terminal receives the jamming command and the jamming signal specification information, and generates and emits a jamming signal based on the jamming command and the jamming signal specification information. The signal detection terminal and the jamming terminal may be configured to be physically separated from each other and may be controlled on a network.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: February 16, 2016
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Jin-Gak Jang, Hui-Rae Cho, In-Ho Hwang, Jong-Kyu Kim, Chun-Soo Kim
  • Patent number: 9261486
    Abstract: The invention relates to a method and a device for detecting, measuring and evaluating defects in an object and/or specific material property of an object using a phased array wave technique. The device comprises of a phased array transceiver probe/source and control unit for use in a phased array wave technique for transmitting and receiving wave signals on and from the area to be inspected. The phased array source is divided into a plurality of virtual probes/sources and each virtual probe/source comprises of plurality of elements arranged sequentially but without phasing for excitation.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: February 16, 2016
    Assignee: INDIAN INSTITUTE OF TECHNOLOGY
    Inventors: Krishnan Balasubramaniam, Saivathan Alavudeen, Chitti Venkatta Krishnamurthy
  • Patent number: 9262862
    Abstract: A method and an apparatus for reconstructing a three dimensional model of an object are provided. The method includes the following steps. A plurality of first depth images of an object are obtained. According to a linking information of the object, the first depth images are divided into a plurality of depth image groups. The linking information records location information corresponding to a plurality of substructures of the object. Each depth image group includes a plurality of second depth images, and the substructures correspond to the second depth images. According to the second depth image and the location information corresponding to each substructure, a local module of each substructure is built. According to the linking information, the local models corresponding to the substructures are merged, and the three-dimensional model of the object is built.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: February 16, 2016
    Assignee: Industrial Technology Research Institute
    Inventors: Yao-Yang Tsai, Hian-Kun Tenn, Jay Huang
  • Patent number: 9262730
    Abstract: A dynamic service network creation apparatus includes a resource lookup and registration unit configured to look up and register network resource information of each of a plurality of network resource providers which are managed by a netstore apparatus; and a service network topology configuration unit configured to, in response to a service reservation request being received from each of a plurality of service providers through a service management system, dynamically configure a service network for providing a network-based service from the service provider to a service user that is to use the service of the service provider, wherein the dynamic service network creation apparatus is connected to the service management system that manages the network-based service provided by a plurality of the service providers and the netstore apparatus.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: February 16, 2016
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Tai-Won Um, Chang-Woo Yoon, Kang-Woon Hong, Nam-Kyung Lee, Ho-Yeon Lee, Seung-Hyun Jeon, Hyun-Woo Lee, Won Ryu