Abstract: Node controllers in power distribution networks in accordance with embodiments of the invention enable dynamic frequency control. One embodiment includes a node controller comprising a network interface a processor; and a memory containing a frequency control application; and a plurality of node operating parameters describing the operating parameters of a node, where the node is selected from a group consisting of at least one generator node in a power distribution network wherein the processor is configured by the frequency control application to calculate a plurality of updated node operating parameters using a distributed process to determine the updated node operating parameter using the node operating parameters, where the distributed process controls network frequency in the power distribution network; and adjust the node operating parameters.
Type:
Application
Filed:
July 10, 2015
Publication date:
February 4, 2016
Applicant:
California Institute of Technology
Inventors:
Changhong Zhao, Enrique Mallada Garcia, Steven H. Low
Abstract: Disclosed is a method and system for browsing a virtual object. A virtual object browsing method includes acquiring identification information of a captured object from the object, acquiring information about a service provider of a virtual object mapped to the identification information, and acquiring related information of the object from the corresponding service provider based on the information about the service provider.
Type:
Application
Filed:
February 12, 2015
Publication date:
February 4, 2016
Applicant:
Korea Advanced Institute of Science and Technology
Inventors:
Jun Kyun Choi, Jin Hong Yang, Hyo Jin Park
Abstract: A method of depositing Ni—Cr and Si coatings onto a turbine component comprising supplying a Ni—Cr target and Si target with a dual-gun magnetron sputtering system; introducing inert gas and negatively biasing the magnet assembly; grounding or negatively biasing the turbine component to be coated; rotating the turbine component, wherein the turbine component has a surface; and forming a Ni—Cr and Si coating on the component surface.
Abstract: Computer-implemented methods and computer-readable media are disclosed for processing call-for-service data to facilitate queries and reports to enhance usefulness of call-for-service data. In one embodiment, a computer-implemented method performable by a computer system includes receiving at a computer system data for a plurality of calls-for-service. Individual data for an individual call-for-service includes one or more fields storing information relating to the call-for-service. Based on the information stored within the one or more fields of the individual data, one or more supplemental classifiers are automatically identified. The one or more supplemental classifiers are associated with the individual data. The one or more supplemental classifiers associated with the individual data enable the individual call-for-service to be identified when the one or more supplemental classifiers match one or more specified criteria.
Type:
Application
Filed:
March 14, 2013
Publication date:
February 4, 2016
Applicant:
Research Triangle Institute
Inventors:
Kevin Jay Strom, Mark William Pope, Maurice A Martin, Christopher Michael Griggs, James IIIiad Rineer, Crystal Majors Daye
Abstract: The present invention provides novel compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and pharmaceutical compositions thereof. The present invention also provides methods and kits using the inventive compounds and pharmaceutical compositions for treating and/or preventing diseases associated with protein aggregation, such as amyloidoses (e.g., Parkinson's disease and Alzheimer's disease), treating and/or preventing neurodegenerative diseases, treating and/or preventing diseases associated with Tar DNA binding protein 43 kDa, reducing or preventing protein aggregation, and/or modulating E3 ubiquitin ligase in a subject in need thereof.
Type:
Application
Filed:
March 17, 2014
Publication date:
February 4, 2016
Applicants:
Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
Inventors:
Susan L. Lindquist, Stephen L. Buchwald, Daniel Tardiff, Nathan Jui
Abstract: Provided is a method of manufacturing a transition metal chalcogenide thin film including providing a substrate having a transition metal film thereon, evaporating a chalcogen source to form a chalcogen material having a second molecular structure, decomposing the chalcogen material having the second molecular structure to form the chalcogen material having the first molecular structure, in which the first molecular structure includes relatively less atoms than the second molecular structure, and providing the chalcogen material having the first molecular structure on a transition metal film.
Type:
Application
Filed:
July 29, 2015
Publication date:
February 4, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Yong-Duck CHUNG, DAEHYUNG CHO, Woo Jung LEE, Won Seok HAN
Abstract: A method of manufacturing a polymer coated single ferromagnetic particle is provided. The method includes hydrophobizing one single hydrophilic ferromagnetic particle by absorbing an aliphatic acid having a hydrophobic aliphatic group and a hydrophilic acid group onto the single ferromagnetic particle to obtain a single hydrophobic ferromagnetic particle; emulsifying the one single hydrophobic ferromagnetic particle with a monomer liquid comprising a nonionic surface activating agent which re-hydrophilizes the one single hydrophobic ferromagnetic particle, to obtain an emulsified liquid; adding a radical addition initiator to the emulsified liquid; and emulsion polymerizing the monomer by radical addition polymerization.
Type:
Application
Filed:
August 20, 2015
Publication date:
February 4, 2016
Applicants:
TOKYO INSTITUTE OF TECHNOLOGY, TAMAGAWA SEIKI KABUSHIKI KAISHA
Abstract: There is provided a compound semiconductor stack including a substrate (101) of which electrical resistance is greater than or equal to 1×105 ?cm, a first compound semiconductor layer (102) which is formed on the substrate (101), and contains In and Sb doped with carbon, and a second compound semiconductor layer (103) which is formed on the first compound semiconductor layer (102), has a carbon concentration less than a carbon concentration of the first compound semiconductor layer (102), and contains In and Sb. A film thickness of the first compound semiconductor layer (102) is greater than or equal to 0.005 ?m and less than or equal to 0.2 ?m. In addition, the carbon concentration of the first compound semiconductor layer (102) is greater than or equal to 1×1015 cm?3 and less than or equal to 5×1018 cm?3.
Type:
Application
Filed:
March 25, 2014
Publication date:
February 4, 2016
Applicants:
ASAHI KASEI MICRODEVICES CORPORATION, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
Abstract: The present invention pertains to the use of engineered variants of enzyme CYP102A, also known as P450-BM3, for cyclopropanation of olefins containing electron-withdrawing groups. One exemplary enzyme variant, referred to as BM3-HStar, contains five mutations away from wild-type P450-BM3, and demonstrates high activity towards cyclopropanation of olefinic substrates using ethyldiazoacetate (EDA) and other carbene transfer reagents. Products of these reactions are potential precursors of levomilnacipran derivatives, a class of compounds that have been shown to be selective inhibitors of monoamine transporters. In addition, cyclopropanation reactions with the P450-BM3 enzyme variants of the invention can be conducted in whole cells expressing the enzyme variants and can proceed under aerobic conditions.
Abstract: The purpose of the present invention is to provide a state estimation apparatus that appropriately estimates the internal state of an observation target by determining likelihoods from a plurality of observations. An observation obtaining unit of the state estimation system obtains, at given time intervals, a plurality of observation data obtained from an observable event. The observation selecting unit selects a piece of observation data from the plurality of pieces of observation data obtained by the observation obtaining unit based on a posterior probability distribution data obtained at a preceding time t?1. The likelihood obtaining unit obtains likelihood data based on the observation data selected by the observation selecting unit and predicted probability distribution data obtained through prediction processing using the posterior probability distribution data.
Type:
Application
Filed:
October 13, 2015
Publication date:
February 4, 2016
Applicants:
MegaChips Corporation, Kyushu Institute of Technology
Abstract: Isolated monoclonal antibodies and antigen binding fragments are disclosed herein that specifically bind polypeptides comprising a histidine phosphorylated at N3 (3-pHis). Nucleic acids encoding these antibodies, vectors including these nucleic acids, and host cells transformed with these vectors and nucleic acids are also disclosed. Methods are also disclosed for using these antibodies, such as for detection of polypeptides comprising a histidine phosphorylated at N3 (3-pHis), detection of a tumor, monitoring the effectiveness of therapeutic agent, and identifying antibiotics. In some embodiments, the methods can be used to investigate signal transduction pathways.
Type:
Application
Filed:
July 1, 2015
Publication date:
February 4, 2016
Applicant:
SALK INSTITUTE FOR BIOLOGICAL STUDIES
Inventors:
Tony Hunter, Stephen Rush Fuhs, Jill Meisenhelder
Abstract: The present invention provides methods of inducing proliferation of and/or differentiating cells comprising contacting cells with compounds within the methods of the invention. The present invention further provides cells obtainable by the methods of the invention. Liver disease affects more than 500 million people worldwide. Organ transplantation is the gold standard for treatment of liver failure, but organ shortages are acute.
Type:
Application
Filed:
March 14, 2014
Publication date:
February 4, 2016
Applicants:
The Broad Institute, Inc., Massachusetts institute of Technology
Inventors:
Sangeeta Bhatia, Jing Shan, Michelle Palmer, Nathan Ross
Abstract: The present invention is aimed to provide a method for preparing an acceptor that is N-glycan hydrolyzed antibody or a Fc fragment thereof used for producing antibody having a homogeneous N-glycan structure; a method for determining a combination of endoglycosidases for use in said preparation; and a method for measuring N-glycans linked to an antibody. The present invention is directed to a method for producing a N-glycan hydrolyzed antibody or Fc fragment thereof, comprising reacting the antibody or the Fc fragment thereof with several endoglycosidases; and a method for determining quantitative information of an objective N-glycan with a desired structure linked to an antibody or a Fc thereof, comprising a protease treatment step and a glycopeptide measurement step, etc.
Type:
Application
Filed:
April 17, 2015
Publication date:
February 4, 2016
Applicants:
THE NOGUCHI INSTITUTE, IMMUNO-BIOLOGICAL LABORATORIES CO., LTD.
Abstract: Methods are disclosed for forming subwavelength coatings for use in the UV, visible, or infrared part of the electromagnetic spectrum. A first material and a second material are deposited onto a substrate. The first material may include dielectric spheres of subwavelength size that self-assemble on the substrate to form a template or scaffold with subwavelength size voids between the spheres into which the second material is deposited or filled. First and second materials are heated on the substrate at a preselected temperature to form the subwavelength coating.
Abstract: The invention features fragments of the Candida cell surface proteins Als3 and Hyr1 and combinations thereof useful in immunizing a subject against fungal or bacterial infections or both.
Type:
Application
Filed:
March 14, 2014
Publication date:
February 4, 2016
Applicants:
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, NovaDigm Therapeutics, Inc.
Inventors:
Ashraf S. IBRAHIM, Michael R. YEAMAN, Scott G. FILLER, John E. EDWARDS, JR., John P. HENNESSEY, JR.
Abstract: Methods of enabling locomotor control, postural control, voluntary control of body movements (e.g., in non-weight bearing conditions), and/or autonomic functions in a human subject having spinal cord injury, brain injury, or neurological neuromotor disease are described.
Type:
Application
Filed:
July 2, 2015
Publication date:
February 4, 2016
Applicants:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC., CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventors:
Victor Reggie Edgerton, Roland R. Roy, Yury Gerasimenko, Joel W. Burdick, Susan J. Harkema, Jonathan Hodes, Yu-Chong Tai, Mandheerej S. Nandra, Claudia A. Angeli, Thomas Anthony Desautels
Abstract: A method for bonding stainless steel members includes: contacting a first stainless steel member with a second stainless steel member that has a strain exceeding 50% reduction; and heating the first and second stainless steel members to a re-crystallization initiation temperature or higher, after the contacting.
Type:
Application
Filed:
October 13, 2015
Publication date:
February 4, 2016
Applicants:
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, KOMATSUSEIKI KOSAKUSHO CO., LTD.
Abstract: Biomedical devices for implantation with decreased pericapsular fibrotic overgrowth are disclosed. The device includes biocompatible materials and has specific characteristics that allow the device to elicit less of a fibrotic reaction after implantation than the same device lacking one or more of these characteristic that are present on the device. Biocompatible hydrogel capsules encapsulating mammalian cells having a diameter of greater than 1 mm, and optionally a cell free core, are disclosed which have reduced fibrotic overgrowth after implantation in a subject. Methods of treating a disease in a subject are also disclosed that involve administering a therapeutically effective amount of the disclosed encapsulated cells to the subject.
Type:
Application
Filed:
March 14, 2014
Publication date:
February 4, 2016
Applicant:
Massachusetts Institute of Technology
Inventors:
Minglin Ma, Daniel G. Anderson, Robert S. Langer, Omid Veiseh, Joshua Charles Doloff, Delai Chen, Christian J. Kastrup, Arturo Jose Vegas
Abstract: The present invention is directed to a monoclonal antibody that recognizes human CD9 in its native form. The invention is also directed to a hybridoma cell line that produces the monoclonal antibody, and exosome isolation kits using the antibody.
Type:
Application
Filed:
March 17, 2014
Publication date:
February 4, 2016
Applicant:
The Translational Genomics Research Institute
Abstract: The present invention provides a new photoreactive compound which can be used in technologies for photoreactions of nucleic acid, and also provides a photoreactive crosslinking agent comprising the above photoreactive compound. A photoreactive compound represented by the following formula I can be used.
Type:
Application
Filed:
March 27, 2014
Publication date:
February 4, 2016
Applicant:
JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY