Abstract: Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.

Abstract: The present invention provides compounds of the Formula (I) and (II), and salts thereof, wherein L1, L2, A, B, Z, and RO are as defined herein. The present invention also provides synthetic intermediates, methods of preparation and use, and kits comprising such compounds. Such compounds, when bound to a label or probe (B), may be useful in various assays for identifying bromodomain binding agents, for example, specific for the BET-family of bromodomains.

Abstract: A suction drain device of a disclosed liquid collecting apparatus actively pushes and pulls blood. This achieves liquid collection at high speed even under decreased pressure depending on a physiological state of an animal. Moreover, the liquid collecting apparatus includes a First flow path and a second flow path having a given length. Accordingly, the flow path with a given length set in advance and thus a known volume allows collection of a given amount volume of blood without measuring a length and an amount of blood using a volume measuring device. Accordingly, no need of the measuring device allows reduction in size of the liquid collecting apparatus. Consequently, the liquid collecting apparatus can be installed adjacent to the animal to achieve reduction in dead volume. Moreover, blood is flown to a fourth flow path branched with a connecting terminal, and is also flown to the second flow path branched with a connecting terminal.

Abstract: A method of imaging electrical conductivity distribution of a subsurface containing metallic structures with known locations and dimensions is disclosed. Current is injected into the subsurface to measure electrical potentials using multiple sets of electrodes, thus generating electrical resistivity tomography measurements. A numeric code is applied to simulate the measured potentials in the presence of the metallic structures. An inversion code is applied that utilizes the electrical resistivity tomography measurements and the simulated measured potentials to image the subsurface electrical conductivity distribution and remove effects of the subsurface metallic structures with known locations and dimensions.

Abstract: The present invention is directed to systems and methods for diagnosing amyotrophic lateral sclerosis (ALS) by assessing the expression level of a marker, FGGY. In other aspects, the present invention is also directed to systems and methods of establishing a prognosis of ALS disease severity by assessing the expression level of FGGY.

Abstract: The invention is directed to compositions and methods for the detection of a malignant condition, and relates to the discovery of soluble and cell surface forms of HE4a polypeptides, including HE4a that is overexpressed in ovarian carcinomas. In particular the invention provides a nucleic acid sequence encoding HE4a, and also provides a method of screening for the presence of a malignant condition in a subject by detecting reactivity of an antibody specific for a HE4a polypeptide with a molecule naturally occurring in soluble and/or cell surface form in a sample from such a subject, and by hybridization screening using an HE4a nucleotide sequence, as well as other related advantages.

Abstract: A robot arm (50) of the present invention includes, as a direct acting extensible/retractable joint (J3), an arm section (2) constituted by an upper structure group (20) and a lower structure group (21). Groups (20) and (21), having an arrangement in which structures are connected in series, partially engage so as to form a direct rigid combined structure, and are separated so as to release the rigid structure. An arm length can be adjusted arbitrarily. Section (2) can have a plane surface having no gap to prevent entry of a finger/dust. Separation of Groups (20) and (21) allows an upper structure (22) and a lower structure (23) to rotate around their rotational axes, to realize compact storage inside a robot arm supporting member (1). It is thus possible to prevent significantly entry of a finger/dust, and provide a compact direct acting extensible and retractable arm mechanism.

Abstract: An air conditioning control device and a method thereof are provided, and the air conditioning control method includes the following steps. A plurality of predetermined state information and a current state information are generated according to environment states of a physical space, and a target state information is selected form the plurality of predetermined state information according to a minimum energy consumption. Moreover, the current state information and the target state information are utilized to generate a current effective temperature value and a target effective temperature value, and a set temperature value and a return-air temperature value are extracted from an air conditioning controller. The current effective temperature value, the target effective temperature value, the set temperature value and the return-air temperature value are utilized to execute fuzzy inference to generate a temperature fine-tuning value.

Abstract: Disclosed herein are an apparatus and method for controlling a lighting network. The apparatus for controlling lighting network includes a control device and a plurality of control gears. The control device generates and transfers commands to control lighting. The plurality of control gears receives the commands from the control device and control lighting. The control device assigns a right to use a lighting network to the control gears, and the control gears send information about a change in a lighting state or error details to the control device using the right to use a lighting network.

Abstract: An augmented reality system includes a plurality of mobile devices. Each mobile device includes: an image capturing unit capturing a real image of a target marker to generate a captured image; a storage unit storing a reference image of the target marker, an individual virtual object and a plurality of interactive composite virtual objects; a wireless communication unit capable of short-distance wireless communication with another mobile device located within a predetermined range; a processing unit determining whether the captured image matches the reference image; and a display unit controlled by the processing unit to display one of the individual virtual object, the interactive composite virtual objects and the captured image.

Abstract: The present invention is directed to RNA monomers comprising O-acetal levulinyl protecting groups at the 2? and/or the 5?-hydroxy functionalities of the ribose moiety. Said monomers may be incorporated into oligoribonucleotides or RNA polynucleotides. Furthermore, the invention is directed to methods for the synthesis of said RNA monomers, oligoribonucleotides and RNA polynucleotides, as well as methods for their deprotection and methods for the use of said compounds and compositions comprising said compounds. In particular, such compounds and compositions comprising them are used in methods for light-directed synthesis of RNA microarrays.

Abstract: Disclosed are genes that, when overexpressed in cells expressing alpha-synuclein, either suppress or enhance alpha-synuclein mediated cellular toxicity. Compounds that modulate expression of these genes or activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to treat or prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity.

Abstract: A cyclic azine compound of formula (1): wherein, Y is C—H or a nitrogen atom, Ar1 is a C6-18 aromatic hydrocarbon group, which may be substituted with an C1-4 alkyl group or a phenyl group, Ar2 is a hydrogen atom, or a C6-18 aromatic hydrocarbon group, which may be substituted with a phenyl group or a pyridyl group, or is a nitrogen-containing condensed ring C9-15 aromatic group, Ar3 is a nitrogen-containing condensed ring C9-15 aromatic group, X is a phenylene group, and n is an integer in the range of 0-3. The cyclic azine compound is useful as a constituent of an organic electroluminescent device.

Abstract: A method of manufacturing a metal foil with microcracks includes placing a metal foil between a first material sheet and a second material sheet and then rolling them to form a plurality of microcracks in the metal foil. The microcracks are penetrating, and a sidewall of each of the microcracks is an irregular rough surface. Two ends of each of the microcracks are acute angles. A sound-absorbing structure includes at least one metal foil and a base plate kept at a distance from the metal foil, wherein at least one resonant cavity air layer is formed between the metal foil and the base plate by the distance, and the metal foil has microcracks.

Abstract: A display structure is provided. The display structure includes a first substrate, a pixel array, a second substrate and an optical component. The pixel array is disposed on the first substrate. Each of pixels of the pixel array includes a light-transparent region and a non-light-transparent region. The second substrate is disposed on the pixel array. The optical component has a microlens structure. After the light passes through the microlens structure, the light passes directly through the plurality of the light-transparent regions without passing through the edge of the plurality of the non-light-transparent regions.

Abstract: A method for producing synthesis gas, including: 1) pre-processing a biomass raw material; 2) pyrolyzing the biomass raw material to yield a pyrolysis gas and a carbon powder; 3) separating the pyrolysis gas from the carbon powder and a solid heat carrier; 4) separating the carbon powder away from the solid heat carrier via a solid-solid separator; 5) conveying the generated pyrolysis gas to a condensate tank for spray condensation, condensing a condensable part in the pyrolysis gas to generate biological fuel oil, pressurizing the generated biological fuel oil by a high pressure oil pump and feeding to a gasification furnace to be gasified; and 6) feeding one part of non-condensable pyrolysis gas to a combustion bed to combust with air, and conveying the other part of the non-condensable pyrolysis gas to the pyrolysis bed as a fluidizing medium.

Abstract: A method for producing steam includes combusting a fuel and an oxidant to generate heat in a combustion stream, and injecting impure water into the combustion stream such that the heat produces a steam stream including particulate matter precipitated from the impure water. A steam generator includes a combustion chamber that has an initial section including an oxidant feed that is substantially free of nitrogen and a fuel feed, and downstream from the initial section at least one liquid water feed.

Abstract: Described herein is a fixed-point piece-wise linear (FP PWL) approximation technique for computations of nonlinear functions. The technique results in circuit designs having relatively few and simple arithmetic operations, short arithmetic operands and small-sized look-up tables and the circuits resultant there from can be efficiently pipelined to run at multi-GSamples/s throughputs. In one exemplary embodiment, the FP PWL approximation technique was used in the design of an energy-efficient high-throughput and high-precision signal component separator (SCS) for use with in an asymmetric-multilevel-outphasing (AMO) power amplifier. The FP PWL approximation technique is appropriate for use in any application requiring high-throughput, area and power constrained hardware implementations of nonlinear functions.

Abstract: Provided is a substrate, including a substrate material, two conductive structures, and at least one diode. The two conductive structures extend from a first surface of the substrate material to a second surface of the substrate material via two through holes penetrating through the substrate material. The at least one diode is embedded in the substrate material at a sidewall of one of the through holes.

Abstract: A method of forming a beam-link by a Base Station (BS) in a wireless communication system using a beamforming scheme includes determining at least one downlink beams to be used for downlink transmission and/or reception, transmitting a reference signal to a Mobile Station via the at least one downlink beam, receiving the reference signal via an uplink beam from the Mobile station, and updating the at least one downlink beam to increase a Signal-to-Noise Ratio (SNR). Accordingly, a beam-link using an initial beam-link between the BS and the MS and adaptive beamforming can be rapidly constructed in a high frequency band BDMA cellular system.