Patents Assigned to INSTITUTE
  • Publication number: 20160024588
    Abstract: Provided herein are methods and compositions for identifying subjects, including canine subjects, as having an elevated risk of developing cancer or having an undiagnosed osteosarcoma. These subjects are identified based on the presence of germ-line risk markers.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 28, 2016
    Applicants: The Broad Institute, Inc., President and Fellows of Harvard College
    Inventors: Elinor Karlsson, Kerstin Lindblad-Toh, Snaevar Sigurdsson, Emma Ivansson
  • Publication number: 20160028403
    Abstract: A three-terminal device that exhibits transistor-like functionality at cryogenic temperatures may be formed from a single layer of superconducting material. A main current-carrying channel of the device may be toggled between superconducting and normal conduction states by applying a control signal to a control terminal of the device. Critical-current suppression and device geometry are used to propagate a normal-conduction hotspot from a gate constriction across and along a portion of the main current-carrying channel. The three-terminal device may be used in various superconducting signal-processing circuitry.
    Type: Application
    Filed: March 11, 2014
    Publication date: January 28, 2016
    Applicant: Massachusetts Institute of Technology
    Inventors: Adam N. McCaughan, Karl K. Berggren
  • Publication number: 20160025592
    Abstract: A bearing test apparatus has a bearing cap coupled to an outer ring of a bearing to be tested (a “test bearing”), a driving rotary shaft coupled to an inner ring of the test bearing to rotate the inner ring, and a bearing torque meter for measuring a single torque of the test bearing, wherein an extension bar is formed at the bearing cap to protrude thereon, wherein the bearing torque meter includes a measurement rod configured to contact the extension bar and be fixed to support the extension bar in a direction opposite to a rotating direction of the driving rotary shaft, and a power sensor for measuring a force applied to the measurement rod, wherein the single torque of the test bearing is calculated based on a distance from the driving rotary shaft to the measurement rod and a force applied to the measurement rod.
    Type: Application
    Filed: October 3, 2014
    Publication date: January 28, 2016
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Yong Bok LEE, Bokseong CHOE, Jeon Kook LEE, Sol-Ji RYU, Byoungkuk LEE
  • Publication number: 20160026722
    Abstract: Disclosed is a content management method, which includes obtaining data for a content including a plurality of point-of-interest (POI) and a plurality of POI documents associated with each of the plurality of POIs, obtaining at least one level-of-detail (LOD) information which allows the content to be displayed according to an interest of the user, and determining a display format for the content based on the LOD information. Here, the LOD information may include information for the interest level of the user with regard to the content, and the interest level may be independent from a scale level of a map at which the content is displayed.
    Type: Application
    Filed: February 9, 2015
    Publication date: January 28, 2016
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Daeil SEO, Byounghyun YOO, Heedong KO
  • Publication number: 20160024662
    Abstract: A system and method are detailed for aluminizing surfaces of metallic substrates, parts, and components with a protective alumina layer in-situ. Aluminum (Al) foil sandwiched between the metallic components and a refractory material when heated in an oxidizing gas under a compression load at a selected temperature forms the protective alumina coating on the surface of the metallic components. The alumina coating minimizes evaporation of volatile metals from the metallic substrates, parts, and components in assembled devices that can degrade performance during operation at high temperature.
    Type: Application
    Filed: September 30, 2015
    Publication date: January 28, 2016
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: Yeong-Shyung Chou, Jeffry W. Stevenson
  • Publication number: 20160028402
    Abstract: A three-terminal device that exhibits transistor-like functionality at cryogenic temperatures may be formed from a single layer of superconducting material. A main current-carrying channel of the device may be toggled between superconducting and normal conduction states by applying a control signal to a control terminal of the device. Critical-current suppression and device geometry are used to propagate a normal-conduction hotspot from a gate constriction across and along a portion of the main current-carrying channel. The three-terminal device may be used in various superconducting signal-processing circuitry.
    Type: Application
    Filed: March 11, 2014
    Publication date: January 28, 2016
    Applicant: Massachusetts Institute of Technology
    Inventors: Adam N. McCaughan, Karl K. Berggren
  • Publication number: 20160029139
    Abstract: Disclosed is an apparatus and method for processing a multichannel audio signal. A multichannel audio signal processing method may include: generating an N-channel audio signal of N channels by down-mixing an M-channel audio signal of M channels; and generating a stereo audio signal by performing binaural rendering of the N-channel audio signal.
    Type: Application
    Filed: April 18, 2014
    Publication date: January 28, 2016
    Applicant: Electronics and Techcommunications Research Institute
    Inventors: Yong Ju LEE, Jeong Il SEO, Seung Kwon BEACK, Kyeong Ok KANG, Jin Woong KIM, Jae Hyoun YOO
  • Publication number: 20160022794
    Abstract: The present invention provides novel enterobactin-carrier protein conjugates and salmochelin-carrier protein conjugates, such as compounds of Formula (I), and salts thereof. The present invention also provides compositions, kits, and methods that involve the compounds of Formula (I) and are useful in inducing an immune response, treating a bacterial infection and/or inflammatory bowel disease in a subject, preventing a bacterial infection and/or inflammatory bowel disease in a subject, or inhibiting the growth of or killing a bacterium.
    Type: Application
    Filed: April 30, 2015
    Publication date: January 28, 2016
    Applicants: Massachusetts Institute of Technology, The Regents of the University of California
    Inventors: Elizabeth Marie Nolan, Phoom Chairatana, Manuela Raffatellu, Martina Sassone Corsi, Araceli Perez-Lopez
  • Publication number: 20160023991
    Abstract: Provided herein are compounds and compositions useful in increasing PPAR? activity. The compounds and compositions provided herein are useful for the treatment of PPAR? related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).
    Type: Application
    Filed: October 2, 2015
    Publication date: January 28, 2016
    Applicants: Salk Institute for Biological Studies, Mitobridge, Inc.
    Inventors: Ronald M. Evans, Michael Downes, Thomas J. Baiga, Joseph P. Noel, Emi Kanakubo Embler, Weiwei Fan, John F.W. Keana, Mark G. Bock, Arthur F. Kluge, Mike A. Patane
  • Publication number: 20160027954
    Abstract: The present disclosure provides improved thin film photovoltaic devices and related methods of fabrication. More particularly, the present disclosure provides improved CdTe photovoltaic devices and related fabrication methods. Disclosed is a novel thin film photovoltaic device and means for its fabrication. An exemplary device includes a metal oxide layer between the absorber layer and the rear electrode, resulting in an ohmic back contact and having improved device stability. The metal oxide layer can include at least one of silver oxide or copper oxide, and may additionally contain nickel oxide, molybdenum oxide, and/or vanadium oxide. The present disclosure is directed towards formation of a ohmic back contact for solar cells, the back contact having improved stability. In certain embodiments, the present disclosure provides for an ohmic contact to p-type II-VI semiconductors, and to the fabrication of solar cells having improved stability, and to solar panels incorporating such back contact schemes.
    Type: Application
    Filed: March 12, 2014
    Publication date: January 28, 2016
    Applicant: New Jersey Institute of Technology
    Inventors: Zimeng Cheng, Ken K. Chin, Alan E. Delahoy
  • Publication number: 20160023168
    Abstract: A complex nanofiltration membrane comprising a substrate and a separating layer, wherein the separating layer is an oxidant-treated, crosslinked network structure formed from a hydroxyl-containing polymer, a thiol-containing silane coupling agent and a crosslinking agent, is disclosed. Also disclosed are a process for preparing the complex nanofiltration membrane and use of the complex nanofiltration membrane in water treatment.
    Type: Application
    Filed: July 22, 2015
    Publication date: January 28, 2016
    Applicants: CHINA PETROLEUM & CHEMICAL CORPORATION, BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION
    Inventors: Yang ZHANG, Yiqun LIU, Guoyuan PAN, Hao YAN, Jian XU, Min GUO
  • Publication number: 20160022599
    Abstract: The present disclosure provides improved stripfilm based pharmaceutical products (e.g., for enhancing dissolution and bioavailability). More particularly, the present disclosure provides improved systems/methods for fabricating stripfilm based pharmaceutical products by utilizing higher viscosity film forming precursors and drying methods that accomplish improved/faster drying and provide improved/excellent content uniformity of active pharmaceutical agents in the stripfilm based pharmaceutical products. Exemplary systems/methods advantageously use high viscosity, bio-compatible polymeric precursors, (optional use of surface modified drug powders), and convective drying for fabrication of thin films loaded with nano and/or micro sized particles of poorly water-soluble active pharmaceutical ingredients (APIs) to achieve improved active content uniformity and very fast dissolution from poorly water soluble actives, while accomplishing fast drying during the fabrication process.
    Type: Application
    Filed: March 17, 2014
    Publication date: January 28, 2016
    Applicant: NEW JERSEY INSTITUTE OF TECHNOLOGY
    Inventors: Rajesh N. Dave, Ramani Susarla, Boris Khusid, Anagha A. Bhakay, Ecevit A. Bilgili, Fernando Muzzio
  • Publication number: 20160028048
    Abstract: An embodiment of the inventive concept provides a lithium battery including: a first pouch film; a first anode part on the first pouch film, the first anode part including a first anode terminal; a second cathode part on the first anode part; a polymer film on the second cathode part; a second anode part on the polymer film, the second anode part including a second anode terminal; a first cathode part on the second anode part; a second pouch film on the first cathode part; and an anode connector configured to penetrate the first and second anode terminals to provide an electrical connection between the first anode part and the second anode part.
    Type: Application
    Filed: July 17, 2015
    Publication date: January 28, 2016
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Young-Gi LEE, Kwang Man KIM, Kunyoung KANG, Dong Ok SHIN
  • Publication number: 20160023403
    Abstract: The present application relates generally to systems and methods for using machine vision to provide information on one or more aspects of an additive fabrication device, such as calibration parameters and/or an object formed by the device or in the process of being formed by the device. According to some aspects, a method is provided for calibrating an additive fabrication device. According to some aspects, a method is provided for assessing at least a portion of an object formed using an additive fabrication device. According to some aspects, a method is provided for fabricating a second object in contact with a first object using an additive fabrication device. According to some aspects, an additive fabrication device configured to perform one or more of the above methods may be provided.
    Type: Application
    Filed: March 12, 2015
    Publication date: January 28, 2016
    Applicant: Massachusetts Institute of Technology
    Inventors: Javier E. Ramos, Pitchaya Sitthi-Amorn, Wojciech Matusik, Yuwang Wang
  • Publication number: 20160027153
    Abstract: A magnetic resonance imaging (MRI) apparatus and an MRI method are provided. The MRI apparatus includes a data acquisition unit configured to acquire a first image by performing an MRI scan on an object. The MRI apparatus further includes an image acquisition unit configured to acquire a second image by performing de-noising filtering on the first image in a spatial domain, acquire a third image based on the first image and the second image, acquire a fourth image by performing low-pass filtering on the third image in a frequency domain, and acquire a final image based on the second image and the fourth image.
    Type: Application
    Filed: June 17, 2015
    Publication date: January 28, 2016
    Applicants: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Jung-hwi EUN, Jong Beom RA
  • Publication number: 20160024157
    Abstract: Polypeptides comprising various amino acid sequences derived from Haemophilus influenzae type b, including a number of lipoproteins. These can be used in the development of vaccines for preventing and/or treating bacterial meningitis. They may also be useful for diagnostic purposes, and as targets for antibiotics. Antibodies against the polypeptides are also disclosed, as are the coding nucleic acids.
    Type: Application
    Filed: October 6, 2015
    Publication date: January 28, 2016
    Applicants: GLAXOSMITHKLINE BIOLOGICALS SA, J. CRAIG VENTER INSTITUTE, INC.
    Inventors: Vega MASIGNANI, Rino RAPPUOLI, Herve TETTELIN
  • Publication number: 20160023904
    Abstract: The present invention generally relates to articles comprising microstructures and methods for forming microstructures. The microstructures may be mechanically coupled to impart complex three dimensional shapes. For example, one or more microstructures may be grown on a substrate at different average growth rates, resulting in curved microstructures.
    Type: Application
    Filed: July 28, 2014
    Publication date: January 28, 2016
    Applicants: Massachusetts Institute of Technology, University of Michigan, The Board of Regents Acting For and On Behalf of the C/O Technology Man
    Inventors: Anastasios John Hart, Sei Jin Park, Sameh Hani Tawfick, Michael FI De Volder
  • Publication number: 20160024535
    Abstract: Provided is a method for producing a saccharified solution of wood-based biomass having toxicity reduced or removed, comprising the steps of: preparing a saccharified solution in which wood-based biomass has been pretreated by hydrolysis; and reducing toxicity in the saccharified solution using an electrochemical detoxification method. The method is capable of efficiently removing the toxicity of compounds which are produced during the pretreatment process and inhibit growth of microorganisms and fermentation. In addition, the method is capable of increasing the efficiency of production by minimizing sugar loss and additional costs during the toxicity removal process.
    Type: Application
    Filed: October 2, 2015
    Publication date: January 28, 2016
    Applicant: Korea Institute of Science and Technology
    Inventors: Youngsoon UM, Yunje KIM, Dongjin SUH, Kyung Min LEE, Jeong Myeong HA
  • Publication number: 20160024110
    Abstract: Provided are a polycyclic pyrazolinone derivative indicated by general formula (1) (in the formula, R1, X1, X2, X3, and Y indicate the definitions provided in the Specification) and a herbicide comprising same as effective component thereof.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 28, 2016
    Applicants: KAKEN PHARMACEUTICAL CO., LTD., SAGAMI CHEMICAL RESEARCH INSTITUTE
    Inventors: Osamu KOBAYASHI, Naoko NIIKURA, Tomoko INOUE, Satoshi MIZUTA, Reiko TAKATSUNA, Kenji HIRAI, Kentaro SHIROUZU, Miyoo OBATA
  • Publication number: 20160028049
    Abstract: Provided is a lithium battery including a first pouch film, a first anode part on the first pouch film, a second cathode part on the first anode part, a polymer insulating film on the second cathode part, the polymer insulating film including a disk which is configured to penetrate the polymer insulating film, a second anode part on the polymer insulating film, a first cathode part on the second anode part, and a second pouch film on the first cathode part. Herein, the second cathode part is electrically connected to the second anode part through the disk.
    Type: Application
    Filed: July 17, 2015
    Publication date: January 28, 2016
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Young-Gi LEE, Kwang Man KIM, Kunyoung KANG, Dong Ok SHIN