Abstract: CsChrimson light-activated ion channel polypeptides, their encoding polynucleotides, and variants thereof are provided. Methods of introducing and using CsChrimson light activated ion channels and variants thereof for to alter cell activity and function are also provided.
Type:
Application
Filed:
August 4, 2015
Publication date:
February 11, 2016
Applicants:
THE GOVERNORS OF THE UNIVERSITY OF ALBERTA, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventors:
Nathan Klapoetke, Brian Yichiun Chow, Edward Boyden, Gane Ka-Shu Wong, Yongku Peter Cho
Abstract: A computer-program causing a computing device to transmit a command to a data storage cluster for multiple data transfer threads thereof to request assignment of a data transfer from a distribution thread; await receipt of a request for assignment from a data transfer thread; compare the quantity data transfer threads to the quantity of computation threads of a data processing cluster; assign to the data transfer thread an exchange of a block of data with a single computation thread in response to receipt of the request and to the multitude of data transfer threads comprising a greater quantity of threads than the multitude of computation threads; and assign to the data transfer thread exchanges of multiple blocks of data with multiple computation threads in response to receipt of the request and to the multitude of data transfer threads comprising a lesser quantity of threads than the multitude of computation threads.
Abstract: An object of the present invention is to provide a method for producing poly(3-hydroxybutyrate-co-3-hydroxyhexanoate (P(3HB-co-3HHx)) having a high 3-hydroxyhexanoate fraction using a vegetable oil as a basic raw material. According to the present invention, a method is provided for producing P(3HB-co-3HHx) having a high 3-HHx fraction using a vegetable oil as a basic raw material by disrupting and so forth at least one gene encoding 2-enoyl-CoA hydratase or at least one gene encoding 3-hydroxyacyl-CoA dehydrogenase on a chromosome of a recombinant Cupriavidus necator strain imparted with the ability to produce P(3HB-co-3HHx).
Type:
Application
Filed:
February 27, 2014
Publication date:
February 11, 2016
Applicants:
Tokyo Institute of Technology, Kaneka Corporation
Abstract: A self-folding machine comprises a laminate including a flexible layer with a first side and a second side; a first rigid layer including at least one gap laminated to the first side of the flexible layer; a second rigid layer including at least one gap laminated to the second side of the flexible layer, wherein the rigid layers are more rigid than the flexible layer; a first contractible layer laminated to the first rigid layer and extending across at least one gap in the first rigid layer; and a second contractible layer laminated to the second rigid layer and extending across at least one gap in the second rigid layer, wherein the first and second contractible layers retract to respectively create folds in the machine across gaps in the first and second rigid layers when activated.
Type:
Application
Filed:
August 6, 2015
Publication date:
February 11, 2016
Applicants:
MASSACHUSETTS INSTITUTE OF TECHNOLOGY, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Inventors:
Samuel M. Felton, Robert J. Wood, Michael T. Tolley, Erik D. Demaine, Daniela Rus
Abstract: A method for synchronization by a D2D terminal in a D2D communication network through receiving a first D2D synchronization signal from at least one D2D synchronization source and performing synchronization according to a synchronization timing reference provided through the first D2D synchronization signal, and a method for negotiating whether to perform a role as a synchronization source with another D2D synchronization source through determining, when a D2D synchronization signal and a D2D synchronization channel are received from at least one D2D synchronization source, whether to maintain a role as the independent synchronization source based on negotiation information for negotiation between synchronization sources included in the D2D synchronization channel, and operating as a relaying synchronization source when the role as the independent synchronization source is not maintained, are provided.
Type:
Application
Filed:
August 6, 2015
Publication date:
February 11, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Changhee LEE, Wooram SHIN, Sung-Min OH, Ae-Soon PARK, Jeong Hwan LEE
Abstract: Disclosed herein are compositions and methods useful for controlling ?-amyloid levels. In particular, the instant invention relates to an antibody that catalyzes hydrolysis of ?-amyloid at a predetermined amide linkage are provided. The present invention also provides a vectorized antibody that is capable of crossing the blood brain barrier and is also capable of catalyzing the hydrolysis of ?-amyloid at a predetermined amide linkage. Also provided are methods for modulating ?-amyloid levels in vivo using antibodies that bind to ?-amyloid. These compositions and methods have therapeutic applications, including the treatment of Alzheimer's disease.
Abstract: A method of forming crystallized semiconductor particles includes: forming amorphous semiconductor particles in a vacuumed aggregation chamber; transporting the amorphous semiconductor particles formed in the vacuumed aggregation chamber to a vacuumed deposition chamber within which a substrate is held; and applying a vapor of a metal catalyst to the amorphous semi-conductor particles while still in transit to the substrate in the vacuumed deposition chamber to induce crystallization of at least portion of the amorphous semiconductor particles via the metal catalyst in the transit, thereby depositing the crystallized semiconductor particles with the metal catalyst attached thereto onto the substrate.
Type:
Application
Filed:
March 7, 2014
Publication date:
February 11, 2016
Applicant:
Okinawa Institute of Science and Technology School Corporation
Inventors:
Singh VIDYA DHAR, Cathal CASSIDY, Mukhles Ibrahim SOWWAN
Abstract: The present invention is directed to methods for treating cancer in a subject, such as a cancer of the endocrine system. In some aspects, the method includes administering to the subject one or more of a polo-like kinase 1 inhibitor, a mouse double minute 2 inhibitor, and/or a mitotic catastrophe inducing compound. In other aspects, the method includes measuring an expression level of one or more markers, including caspase 8 and caspase 9, to assess the functionality of the caspase cascade in the subject.
Type:
Application
Filed:
October 23, 2015
Publication date:
February 11, 2016
Applicant:
THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
Inventors:
Kimberly J. Bussey, Michael J. Demeure, Aditi Bapat
Abstract: An optoelectronic device as well as its methods of use and manufacture are disclosed. In one embodiment, an optoelectronic device includes first and second semiconducting atomically thin layers with corresponding first and second lattice directions. The first and second semiconducting atomically thin layers are located proximate to each other, and an angular difference between the first lattice direction and the second lattice direction is between about 0.000001° and 0.5°, or about 0.000001° and 0.5° deviant from of a Vicnal angle of the first and second semiconducting atomically thin layers. Alternatively, or in addition to the above, the first and second semiconducting atomically thin layers may form a Moiré superlattice of exciton funnels with a period between about 50 nm to 3 cm. The optoelectronic device may also include charge carrier conductors in electrical communication with the semiconducting atomically thin layers to either inject or extract charge carriers.
Abstract: Provided are a YAG-based single crystal phosphor which produces fluorescence in an unconventional color and a phosphor-containing member and a light emitting device including the single crystal phosphor. Provided is a single crystal phosphor which includes a composition represented by composition formula (Y1?a?bLuaCeb)3+cAl5?cO12 (wherein 0?a?0.9994, 0.0002?b?0.0067 and ?0.016?c?0.315), and in which CIE chromaticity coordinates x and y of an emission spectrum satisfy a relationship of ?0.4377x+0.7384?y??0.4585x+0.7504 when a peak wavelength of excitation light is 450 nm and temperature is 25° C.
Type:
Application
Filed:
October 22, 2014
Publication date:
February 11, 2016
Applicant:
National Institute for Materials Science
Abstract: Methods of forming an organic thin film transistor are provided. The methods include providing a substrate and depositing and patterning a gate electrode on a first surface of the substrate. The methods include dispensing a first droplet of an insulating material on the gate electrode on the substrate and dispensing a second droplet of a semiconductor material on a first surface of the first droplet. The second droplet forms a hydrophobic structure having a central cavity. The methods also include dispensing a third droplet of a conductor material on a first surface of the second droplet such that the conductor material substantially fills the central cavity of the hydrophobic structure and forms a conductor material layer around the central cavity to define a source electrode and a drain electrode of the organic thin film transistor.
Abstract: Embodiments of the invention provide a method of genotyping a C. gattii sample, which can include forming a plurality of mixtures for nucleic amplification. The method can include amplification of specific sequences within the C. gattii genome that can provide definitive genotype information to distinguish between one or more types or subtypes of C. gattii.
Type:
Application
Filed:
August 6, 2015
Publication date:
February 11, 2016
Applicants:
THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE, ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNVERSITY
Inventors:
David Engelthaler, Elizabeth Driebe, Erin Kelley, Paul Keim
Abstract: The present invention provides compositions useful to induce immune response to human metapneumovirus. Also provided are related materials and methods, including methods to induce an immune response in a mammal, comprising administering the compositions herein.
Type:
Application
Filed:
March 14, 2014
Publication date:
February 11, 2016
Applicants:
Ohio State Innovation Foundation, Research Institute at Nationwide Children's Hospital
Inventors:
Jianrong Li, Yongwei Wei, Yu Zhang, Mark E. Peeples
Abstract: A computer-program causing a computing device to transmit, from a data transfer thread of a multitude of data transfer threads executed within a data storage cluster and to a distribution thread at a network address on a network, a request for an assignment of an exchange of data with at least one computation thread of a multitude of computation threads executed within a data processing cluster; exchange a block of data with a single computation thread of the multitude of computation threads in response to receipt of an assignment to exchange the block of data with the single computation thread; and exchange multiple blocks of data with multiple computation threads of the multitude of computation threads in a round robin manner among the multiple computation threads in response to receipt of an assignment to exchange the multiple blocks of data with the multiple computation threads.
Abstract: The present invention provides methods for catalyzing a nitrene insertion into a C—H bond to produce a product having a new C—N bond, comprising providing a C—H containing substrate, a nitrene precursor and an engineered heme enzyme; and allowing the reaction to proceed for a time sufficient to form a regioselective product having a new C—N bond.
Abstract: A method of preparing a lithium phosphate-based solid electrolyte according to an embodiment of the present invention may include preparing a precursor solution which includes a lithium compound, a phosphate compound, and an aluminum compound, forming a first intermediate by performing a hydrothermal reaction process on the precursor solution, forming a second intermediate by calcinating the first intermediate, and crystallizing the second intermediate. The precursor solution may further include a metal compound or a metalloid compound. The lithium phosphate-based solid electrolyte of the present invention may have high ionic conductivity and high purity.
Type:
Application
Filed:
October 19, 2015
Publication date:
February 11, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Kunyoung KANG, Young-Gi LEE, Kwang Man KIM, Dong Ok SHIN
Abstract: The invention generally provides supplements and methods of using the same to improve cognitive functions such as learning, memory, concentration, focus, attention, and mood.
Abstract: There is provided a transmission/reception method of a base station in a device to device (D2D) communication environment in which terminals directly communicate with each other. The base station variably sets the transmission power intensity of a downlink signal over time. Furthermore, the base station broadcasts the downlink signal with set transmission power intensity.
Type:
Application
Filed:
August 6, 2015
Publication date:
February 11, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Kyoung Seok LEE, Mi Young YUN, Ae-Soon PARK
Abstract: An optical waveguide for optical interconnection including a polymer sheet comprising a crosslinked product of a prepolymer, the prepolymer prepared by condensation reaction between a first compound represented by the formula Ar—H, where Ar comprises (a) a crosslinkable moiety at one end, (b) a moiety selected from the group consisting of —O—, —S—, —COO—, —CO—, —COS—, —SO2—, and —NH—, and (c) one or two repeating units selected from the group consisting of: where A is carbon or nitrogen, and X is hydrogen or halogen; and a second compound consisting of an aromatic moiety.
Type:
Application
Filed:
October 21, 2015
Publication date:
February 11, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Seung Koo PARK, Jung Jin JU, Suntak PARK, Jong-Moo LEE, Min-su KIM, Jin Tae KIM, Joong-Seon CHOE