Patents Assigned to INSTITUTE
  • Patent number: 8968740
    Abstract: The present invention is based, in part, on the discovery that galectin-1 (Gal1) plays a role in viral-associated PTLD, e.g., EBV-associated PTLD and hypoxia associated angiogenesis disorders. Accordingly, the invention relates to compositions, kits, and methods for diagnosing, prognosing, monitoring, treating and modulating viral-associated PTLD, e.g., EBV-associated PTLD and hypoxia associated angiogenesis disorders.
    Type: Grant
    Filed: November 12, 2010
    Date of Patent: March 3, 2015
    Assignees: Dana-Farber Cancer Institute, Inc., The Brigham and Women's Hospital, Inc., Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Fundacion Sales
    Inventors: Margaret A. Shipp, Jing Ouyang, Kunihiko Takeyama, Jeffery L. Kutok, Scott J. Rodig, Gabriel Rabinovich, Diego Omar Croci Russo, Mariana Salatino
  • Patent number: 8966774
    Abstract: Provided are embodiments of a section marking apparatus and method for dividing a geological survey site into one or more sections. In some embodiments, the section marking apparatus includes a case part, a fixing shaft part, a section marking part, and a driving pin part. The fixing shaft part is accommodated in the case part. The section marking part is coupled to the fixing shaft part, received in the case part, and has a marker string configured to be extracted to the outside of the case part. The driving pin part is coupled to the fixing shaft part and configured to be driven into a ground surface to secure the section marking apparatus to the ground surface. Accordingly, the section marking apparatus can be used to divide a site when the ground is flat or when the ground is uneven and/or has a slope.
    Type: Grant
    Filed: September 18, 2012
    Date of Patent: March 3, 2015
    Assignee: Korea Institute of Geoscience and Mineral Resources
    Inventors: Sung-Ja Choi, Il-Mo Kang
  • Patent number: 8968470
    Abstract: Disclosed herein are a graphite crucible for electromagnetic induction-based silicon melting and an apparatus for silicon melting/refining using the same, which performs a melting operation by a combination of indirect melting and direct melting. The crucible is formed of a graphite material and includes a cylindrical body having an open upper part through which a silicon raw material is charged into the crucible, and an outer wall surrounded by an induction coil, wherein a plurality of slits are vertically formed through the outer wall and an inner wall of the crucible such that an electromagnetic force created by an electric current flowing in the induction coil acts toward an inner center of the crucible to prevent a silicon melt from contacting the inner wall of the crucible.
    Type: Grant
    Filed: September 28, 2009
    Date of Patent: March 3, 2015
    Assignee: Korea Institute of Energy Research
    Inventors: Bo Yun Jang, Young Soo Ahn, Joon Soo Kim, Sang Hyun Park, Dong Kook Kim, Gwon Jong Yu
  • Patent number: 8968687
    Abstract: A method for recycling metals is provided by using extracellular proteins excreted by a specific thermophilic bacteria strain, Tepidimonas fonticaldi sp. nov., in which the extracellular proteins show excellent metal-ion binding ability, being useful in recycling rare earth metal ions and precious metal ions from geothermal fluids, boiler solutions, industrial wastewater or hard water.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: March 3, 2015
    Assignee: Industrial Technology Research Institute
    Inventors: Yin-Lung Han, Tai-Rong Guo, Jo-Shu Chang, Yung-Chong Lou, Wan-Ju Yu
  • Patent number: 8969800
    Abstract: An ion manipulation method and device to prevent loss of ions is disclosed. The device includes a pair of surfaces. An inner array of electrodes is coupled to the surfaces. A RF voltage and a DC voltage are alternately applied to the inner array of electrodes. The applied RF voltage is alternately positive and negative so that immediately adjacent or nearest neighbor RF applied electrodes are supplied with RF signals that are approximately 180 degrees out of phase.
    Type: Grant
    Filed: October 30, 2014
    Date of Patent: March 3, 2015
    Assignee: Battelle Memorial Institute
    Inventors: Aleksey Tolmachev, Richard D. Smith, Yehia M. Ibrahim, Gordon A. Anderson, Erin M. Baker
  • Patent number: 8967374
    Abstract: A device and method are provided for storing medicaments and foods and/or beverages separately during shelf life, and for mixing the medicaments and foods and/or beverages when ready for use. A body of the device defines a plurality of first chambers for receiving a medicament, and a plurality of second chambers for receiving a food and/or beverage. A first sealing portion is located between the first and second chambers and is movable between a closed position preventing fluid communication between the chambers, and an open position permitting fluid communication between the first and second chambers for mixing the medicament and the food and/or beverage when ready for use.
    Type: Grant
    Filed: May 18, 2007
    Date of Patent: March 3, 2015
    Assignee: Dr. Py Institute LLC
    Inventor: Daniel Py
  • Patent number: 8972184
    Abstract: An apparatus and method for determining an orbit of a geostationary satellite is provided. The orbit of the geostationary satellite may be determined using at least one pseudo-range of the geostationary satellite calculated based on an orbit and a position of at least one global positioning system (GPS) satellite, position information of the geostationary satellite, and an angle between the geostationary satellite and each GPS satellite.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: March 3, 2015
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Yoo La Hwang, Byoung Sun Lee
  • Patent number: 8968425
    Abstract: Disclosed is a method for producing a renewable fuel using a supercritical fluid. The method includes charging a supported catalyst into a continuous reactor and adding a catalyst activating material thereto to activate the supported catalyst, feeding an oil or fat, hydrogen and a supercritical fluid into the continuous reactor and allowing hydrogenation and hydrodeoxygenation reactions of the oil or fat in the supercritical fluid to proceed, and collecting a renewable fuel as the reaction product. The method enables the production of an oxygen-free renewable fuel in a higher yield at a lower hydrogen pressure and a lower reaction temperature than conventional methods for producing renewable fuels.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: March 3, 2015
    Assignee: Korea Institute of Science and Technology
    Inventors: Jaehoon Kim, Jong Min Park, Jae Young Han, Seok Ki Kim
  • Patent number: 8968643
    Abstract: The object of the present invention is to provide an Ni-based single crystal super alloy capable of improving strength by preventing precipitation of a TCP phase at high temperatures. This object is achieved by an Ni-based single crystal super alloy having a composition comprising 5.0-7.0 wt % of Al, 4.0-10.0 wt % of Ta, 1.1-4.5 wt % of Mo, 4.0-10.0 wt % of W, 3.1-8.0 wt % of Re, 0-0.50 wt % of Hf, 2.0-5.0 wt % of Cr, 0-9.9 wt % of Co and 4.1-14.0 wt % of Ru in terms of its weight ratio, with the remainder consisting of Ni and unavoidable impurities. Furthermore, in this Ni-based single crystal super alloy, when lattice constant of matrix is taken to be a1 and lattice constant of precipitation phase is taken to be a2, a2?0.999a1.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: March 3, 2015
    Assignees: National Institute for Materials Science, IHI Corporation
    Inventors: Toshiharu Kobayashi, Yutaka Koizumi, Tadaharu Yokokawa, Hiroshi Harada, Yasuhiro Aoki, Mikiya Arai, Shoju Masaki
  • Patent number: 8970099
    Abstract: The present disclosure relates to an ionization chamber with a built-in temperature sensor, which is especially adapted for devices, such as X-ray units, gamma irradiators and linear accelerators, whichever is used for performing radiation dose output measurement accordingly. In an embodiment, the ionization chamber comprises: a cavity, an inner electrode, a chamber wall, an outer electrode, a guard electrode and a calibrated temperature sensor for detecting real-time temperature inside the cavity of ionization chamber to be used in the correction process of radiation dose measurement signals. With the aforesaid device, not only the accuracy of measurement can be improved effectively, but also the time consumed in a radiation dose measurement period can be reduced greatly since it will no longer bear the disadvantage that the radiation dose measurement has to wait until the temperatures inside and outside the cavity of ionization chamber had reached a thermal equilibrium before the measurement.
    Type: Grant
    Filed: October 9, 2013
    Date of Patent: March 3, 2015
    Assignee: Institute of Nuclear Energy Research Atomic Energy Council, Executive Yuan
    Inventors: Jeng-Hung Lee, Shi-Hwa Su, Tzeng-Te Huang, Bor-Jing Chang
  • Patent number: 8969076
    Abstract: The invention provides methods and compositions for the expression of small RNA molecules within a cell using a lentiviral vector. The methods can be used to express doubles stranded RNA complexes. Small interfering RNA (siRNA) can be expressed using the methods of the invention within a cell, which are capable of down regulating the expression of a target gene through RNA interference. A variety of cells can be treated according to the methods of the invention including embryos, embryogenic stem cells, allowing for the generation of transgenic animals or animals constituted partly by the transduced cells that have a specific gene or a group of genes down regulated.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: March 3, 2015
    Assignee: California Institute of Technology
    Inventors: Carlos Lois-Caballe, David Baltimore, Xiao-Feng Qin
  • Patent number: 8969295
    Abstract: The present invention provides methods for identifying genes and pathways involved in plasticity. The invention applies some of these methods to identify genes that are differentially regulated in at least a portion of the nervous system of an individual subjected to conditions known to result in altered nervous system plasticity, i.e., dark rearing (DR) or monocular deprivation (MD). The genes are targets for pharmacological agents that modify plasticity. The invention also identifies biological pathways that are enriched in genes that are differentially regulated under conditions known to result in altered nervous system plasticity. The present invention further provides methods and compositions for modifying plasticity in the nervous system of a subject.
    Type: Grant
    Filed: April 12, 2007
    Date of Patent: March 3, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Mriganka Sur, Daniela Tropea, Gabriel Kreiman
  • Patent number: 8971388
    Abstract: An RF receiver/transmitter apparatus for carrier aggregation is disclosed, to provide a routing circuitry formed by a plurality of mixer modules for achieving both the function of carrier aggregation and the mixing frequency process of signals. This architecture allows sharing an RF front-end, improving degree of integration, and reducing hardware cost and circuitry power consumption. In addition, in the process of reception and transmission, the apparatus may perform different processing and configuration for each sub-channel to increase circuit design flexibility. The receiver apparatus includes at least one antenna, a first signal processing unit, a routing mixer device, a second signal processing unit and a digital signal processor (DSP); and the routing mixer device includes a plurality of mixer module and a plurality of current/voltage adders to achieve signal routing control through opening or closing of the mixer, switching the signal transmission path or switching the signal synthesizer.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: March 3, 2015
    Assignee: Industrial Technology Research Institute
    Inventors: Chia-Hao Tu, Chang-Ming Lai, Jian-Yu Li
  • Patent number: 8969353
    Abstract: Aminoalcohol lipidoids are prepared by reacting an amine with an epoxide-terminated compound are described. Methods of preparing aminoalcohol lipidoids from commercially available starting materials are also provided. Aminoalcohol lipidoids may be prepared from racemic or stereochemically pure epoxides. Aminoalcohol lipidoids or salts forms thereof are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the amino moiety of these aminoalcohol lipidoid compounds, they are particularly suited for the delivery of polynucleotides. Complexes, micelles, liposomes or particles containing the inventive lipidoids and polynucleotide have been prepared. The inventive lipidoids may also be used in preparing microparticles for drug delivery. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: March 3, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Kerry Peter Mahon, Kevin Thomas Love, Christopher G. Levins, Kathryn Ann Whitehead, Robert S. Langer, Daniel Griffith Anderson
  • Patent number: 8968929
    Abstract: The present disclosure is directed at an electrode and methods for forming such electrode for a battery wherein the electrode comprises silicon clathrate. The silicon clathrate may include silicon clathrate Si46 containing an arrangement of 20-atom and 24-atom cages fused together through 5 atom pentagonal rings and/or silicon clathrate Si34 containing an arrangement of 20-atom and 28-atom cages fused together through 5 atom pentagonal rings. The silicon clathrate may be present as particles having a largest linear dimension in the range of 0.1 ?m to 100.0 ?m.
    Type: Grant
    Filed: July 23, 2010
    Date of Patent: March 3, 2015
    Assignee: Southwest Research Institute
    Inventors: Kwai S. Chan, Candace K. Chan, Wuwei Liang
  • Patent number: 8969254
    Abstract: Oligonucleotide-based microarrays for tissue typing (e.g., HLA tissue typing) are provided. More particularly, the microarrays are high resolution arrays useful for diagnostic evaluations and determining donor/recipient transplant compatibility.
    Type: Grant
    Filed: December 16, 2011
    Date of Patent: March 3, 2015
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Ellis L. Reinherz, Vladimir Brusic, Guanglan Zhang, Derin Benerci Keskin, David Deluca, Honghuang Lin
  • Patent number: 8972313
    Abstract: An apparatus for the learning emotion of a robot includes an internal state calculation unit for detecting external environment information and calculating an internal state vector value for one point of an internal state coordinate system; an emotion decision processing unit for generating an emotion value within each emotion value group, indicated by the coordinates of the internal state input value of the robot on the coordinate system, as an emotion of the robot; a behavior generation unit for deciding the behavior of the robot based on the decided motion value and making an emotional expression; and an emotion learning unit for generating feedback information on the emotion value, corresponding to one point of the coordinate system, based on the decided emotion value and information on the type of emotion from a user input unit and changing an emotion probability distribution of the coordinate system using the feedback information.
    Type: Grant
    Filed: October 1, 2012
    Date of Patent: March 3, 2015
    Assignee: Korea Institute of Industrial Technology
    Inventors: Ho Seok Ahn, Dong Wook Lee, Woong Hee Shon
  • Patent number: 8971912
    Abstract: Disclosed embodiments include a method of paging one of a plurality of mobile subscribers in a wireless communication network. The method includes receiving, at a base station, an idle mode request from the one mobile subscriber and sending an idle mode notification to a control device, after receiving the idle mode request from the one mobile subscriber. The method also includes receiving a paging request from the control device and sending a paging advertisement intended for the one mobile subscriber, after receiving the paging request from the control device.
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: March 3, 2015
    Assignee: Industrial Technology Research Institute
    Inventors: Chie-Ming Chou, Jung-Mao Lin
  • Patent number: 8967457
    Abstract: A total history management system using a radio frequency identification (RFID) tag and a barcode. The system includes an RFID tag, a barcode recorder and a barcode reader. The RFID tag is attached to a box containing a plurality of individual products to store an environmental history of a distribution. The barcode recorder is configured to provide, to each of the plurality of individual products, a barcode in which identification (ID) information of the RFID tag is recorded. The barcode reader is configured to recognize the barcode attached to each of the plurality of individual products, and to output the environmental history of the distribution, corresponding to the ID information of the RFID tag that is received in response to a query with respect to the RFID tag, using the recognized barcode.
    Type: Grant
    Filed: August 28, 2012
    Date of Patent: March 3, 2015
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Dong Beom Shin, Heyung Sub Lee, Sang Hyun Mo, Kang Bok Lee, Jae Heum Lee, Cheol Sig Pyo
  • Patent number: 8971657
    Abstract: The invention provides a method for improving image quality. Through applying variation value during operation of iterated algorithm, this invention can reduce blur phenomenon caused by partial volume effects and improve image accuracy. In an embodiment, by applying the algorithm utilized in the method for improving image quality, this invention further provides an imaging system to detect the distribution of the object, thereby obtaining a clear restored image corresponding to the radiation source.
    Type: Grant
    Filed: August 8, 2013
    Date of Patent: March 3, 2015
    Assignee: Institute of Nuclear Energy Research Atomic Energy Council, Executive Yuan
    Inventors: Fan-Pin Tseng, Meei-Ling Jan, Yu-Ching Ni