Abstract: A compliant mechanism is provided for accurate and precision alignment of mechanical component parts, surfaces or assemblies and the like, where low-cost, accurate, and repeatable alignment are desired. The compliant mechanism may be used in applications that require high precision alignment and where the relative location of coupled components must be variable or adjustable. The compliant mechanism includes a stage coupled to a plurality of hinges, at least one tab coupled to one of the hinges, and a support coupled to the tab. The relative position of the stage and the support may be adjusted by actuating (i.e., displacing) the tab(s) or other parts of the structure, to enable controlled movement in six degrees of freedom therebetween.

Abstract: The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be used in screening and diagnosis assays for abnormal GENSET expression and/or biological activity and for screening compounds that may be used in the treatment of GENSET-related disorders.

Abstract: A catalyst for the preparation of dimethyl carbonate from urea and methanol having a composition on weight base of: active component of from 20 to 50 wt %, and carrier of from 80 to 50 wt %, and prepared by equal-volume spraying and impregnating method is disclosed. The method for the synthesis of dimethyl carbonate can be carried out in a catalytic rectification reactor, said method comprising: (1) dissolving urea in methanol to form a methanol solution of urea; and (2) feeding the methanol solution of urea and methanol counter-currently into the reaction zone, wherein the reaction is carried out at conditions including reaction temperature of from 120° C. to 250° C., reaction pressure of from 0.1 MPa to 5 MPa, kettle bottom temperature of from 70° C. to 210° C., stripping section temperature of from 70° C. to 250° C., rectifying section temperature of from 70° C. to 280° C., and reflux ratio of from 1:1 to 20:1.

Abstract: In general, in one aspect, the invention features an article including a high-power, low-loss fiber waveguide that includes alternating layers of different dielectric materials surrounding a core extending along a waveguide axis, the different dielectric materials including a polymer and a glass.

Abstract: Disclosed is a catalyst for a partial oxidation reforming reaction of fuel in the form of disk having through-hole. In addition, according to the invention, there is provided a fuel reforming apparatus and method using the catalyst. The catalyst for a partial oxidation reforming reaction of fuel according to the invention makes it possible to progress the partial oxidation reforming reaction of fuel smoothly, to improve the efficiency when reforming the fuel and to simplify the fuel reforming reactor. According to the fuel reforming apparatus and method, since the heat of reaction is efficiently controlled and used, a simple on-off operation, reduction of starting time and a stable operational condition are accomplished, which are indispensably required for a fuel reforming system in fuel cells, such as household, portable and car fuel cells.

Abstract: A light source device and projector using the same is provided. The light source device includes multiple light source modules and a multi-channel optical light tube. The multi-channel optical light tube includes multiple channels, each of which has a light guiding portion and corresponds to one or more of the light source modules. The light source module transmits the output light to the corresponding light channel, and the light guiding portion of each light channel is provided with a reflective surface for combining the light input through the light channels to the multi-channel optical light tube, thus providing the output of the light source device.

Abstract: The invention is directed to compositions and methods for the detection of a malignant condition, and relates to the discovery of soluble and cell surface forms of HE4a polypeptides, including HE4a that is overexpressed in ovarian carcinomas. In particular the invention provides a nucleic acid sequence encoding HE4a, and also provides a method of screening for the presence of a malignant condition in a subject by detecting reactivity of an antibody specific for a HE4a polypeptide with a molecule naturally occurring in soluble and/or cell surface form in a sample from such a subject, and by hybridization screening using an HE4a nucleotide sequence, as well as other related advantages.

Abstract: This invention involves a two-level variable chip rate spreading and despreading method used in CDMA systems. The total spreading gain is the product of the two level spreading factors. Orthogonal sequences, ZCZ sequences and Pseudo-Noise (PN) sequences can be employed as the first- and second-level spreading codes. By employing the two-level spreading method, the interference existing in the systems can be suppressed efficiently and the system performance can be improved significantly.

Abstract: In accordance with the present invention, there are provide novel receptor interacting factors, referred to herein as “SMRT”, i.e., a silencing mediator (co-repressor) for retinoic acid receptor (RAR) and thyroid hormone receptor (TR). SMRT is a novel protein whose association with RAR and TR both in solution and on DNA response elements is destabilized by ligand. The interaction of SMRT with mutant receptors correlates with the transcriptional silencing activities of receptors. In vivo, SMRT functions as a potent co-repressor. A GAL4 DNA binding domain (DBD) fusion of SMRT behaves as a frank repressor of a GAL4-dependent reporter. Together, these data identify a novel class of cofactor which is believed to represent an important mediator of hormone action.

Abstract: The present invention relates to 3,4-dihydroquinazoline derivatives as T-type calcium channel blockers and a method of preparing the same. The present invention further relates to a composition comprising the same. The composition comprising the 3,4-dihydroquinazoline derivatives of the present invention can be effectively used for preventing and treating angina pectoris, high blood pressure, myocardial disease, pain and epilepsy by blocking the T-type calcium channel.

Abstract: Various aspects and applications of microsystem process networks are described. The design of many types of Microsystems can be improved by ortho-cascading mass, heat, or other unit process operations. Microsystems having energetically efficient microchannel heat exchangers are also described. Detailed descriptions of numerous design features in microcomponent systems are also provided.

Abstract: Sensor for use in highly sensitive analytical devices for qualitative and quantitative analysis of natural waters and technology-related solutions, containing low concentrations of components determined. Design of a sensor provides for simplification and costs reduction of its manufacture, widening range of solutions analyzed, improvement of their kinetic characteristics and increase in analysis sensitivity. Sensor has multichannel structure in a form of a piece 1 of a polycapillary tube with through capillaries forming microchannels filled up with two layers of immiscible substances. One layer (4) is formed of water or aqueous solution, and another layer (3) is formed of organic substance. The first of the layers in microchannels contains sorbent microgranules 5.

Abstract: This invention generally relates to methods of producing an antibody phage population having affinity for a tumor cell target expressing a metastatic phenotype. The invention further relates to antibody compositions that specifically bind to a cell surface receptor on the metastatic cell.

Abstract: A method for speech processing in a code excitation linear prediction (CELP) based speech system having a plurality of modes including at least a first mode and a consecutive second mode. The method includes providing an input speech signal, dividing the speech signal into a plurality of frames, dividing at least one of the plurality of frames into sub-frames including a plurality of pulses, selecting a first number of pulses for the first mode, with a second number of remaining pulses in the frame plus the first number of pulses in the first mode for the second mode, providing a plurality of sub-modes between the first mode and the second mode, forming a base layer, forming an enhancement layer, generating a bit stream including a basic bit stream and an enhancement bit stream, wherein the basic bit stream is used to update memory states of the speech system.

Abstract: The present invention relates to a method for disrupting a gene in a plant using a tobacco retrotransposon, comprising the steps of introducing the retrotransposon into the plant, and culturing and regenerating the plant, into which the retrotransposon is introduced, to produce a transformed plant.

Abstract: Bifunctional molecules comprising two hsp-binding moieties which bind to hsp90 in the pocket to which ansamycin antibiotics bind connected via a linker are effective for inducing the degradation and/or inhibition of HER-family tyrosine kinases. For example, a compound of two geldanamycin moities joined by a four-carbon linker provides selective degradation of HER-family tyrosine kinases, without substantially affecting other kinases. These compounds can be used for treatment of HER-positive cancers with reduced toxicity, since these compounds potently kill cancer cells but affect fewer proteins than geldanamycin.

Abstract: The present invention discloses an organic-inorganic hybrid composition with sufficient flexibility, a high dielectric constant, which can be used as a bonding layer having a high thermal stability and high dielectric constant. The composition includes a) a high Tg epoxy resin system; b) ferroelectric ceramic particles having two particle size distributions, with one of them pertaining to a nano level; c) an electrically conductive powder, such as an electrically conductive carbon black; d) at least one macromolecular flexibilizer; e) a macromolecular dispersant; and f) additives such as a diluent, an adhesive promoter, a hardener, a hardener promoter, and an organic solvent.

Abstract: QoS router system and method are provided for effectively processing fragmented IP packets transmitted over a network. When receiving a first fragmented IP packet of a set from a flow, a router determines whether to allow the first packet to pass or to drop by according to predefined QoS rules. A pass status is recorded in a record if the packet is allowed to pass. A drop status is recorded in the record if the packet is dropped. When receiving other fragmented IP packet of the same set, the router determines whether to allow the fragmented packet to pass or to drop by according to the previous record. If the record is drop status, the packet is dropped, and if the record is pass status, the packet is allowed to pass when the used bandwidth of the flow does not exceeds a predetermined bandwidth.

Abstract: Described is a tile module for a phased array system. The tile module includes array elements configured in a two-dimensional array which is part of a larger subarray in the phased array system. A control module communicates with each array element to control a phase shift and an attenuation. In one embodiment a two-dimensional overlapped subarray manifold provides a weighted combination of RF signals received by the array elements of the tile module and array elements of other tile modules disposed in the same subarray of the phased array system. In another embodiment the two-dimensional overlapped subarray manifold distributes to the array elements weighted combinations of transmit RF signals applied to the tile module and other tile modules disposed in the same subarray. Advantageously, tile modules can be fabricated in large quantities, can be tested and calibrated independently, and can easily be installed or replaced in the phased array system.

Abstract: Disclosed is a crawler robot which, even of a small size, can climb over a high step and which can perform various aspects of operations. Rollers, are arranged at apexes of triangular frames, and elastic crawlers are wrapped around the rollers, with the two frames being connected by a central support shaft. Rotatably provided to the central support shaft is a one-joint link composed of a first link and a second link connected together by a rotation shaft. An end portion of the second link is rotatably connected with a front shaft of a subordinate crawler device equipped with crawlers wrapped around rollers. As a result, the crawler robot is composed of a triangular crawler device and the subordinate crawler device connected together by the one-joint link. The crawler robot can be operated by rotating and bending the link and by rotating the crawler devices in arbitrary directions.