Patents Assigned to INSTITUTE
  • Publication number: 20060217919
    Abstract: According to an embodiment of the invention, a system for identifying when a running speed of an integrated circuit is within an applied clock speed is provided. A monotonic circuit is configured to receive input data and transmit output data. A completion detection circuit is configured to generate a completion detection signal for the monotonic circuit. A comparator is configured to compare at least the completion detection signal and a clock signal, and configured to emit an error signal if the clock signal arrives before the completion detection signal. A synchronous circuit element is configured to receive at least a portion of the output data and configured to be clock driven by the clock signal. The error signal represents that the clock speed is faster than an operating speed of the monotonic circuit.
    Type: Application
    Filed: January 12, 2006
    Publication date: September 28, 2006
    Applicant: Institute of Computer Science, Foundation for Research and Technology - Hellas ("ICS")
    Inventor: Christos Sotiriou
  • Patent number: 7112420
    Abstract: The invention provides isolated nucleic acids molecules, designated BBAP nucleic acid molecules, which encode proteins that interact with or bind to BAL molecules, which are differentially expressed in non-Hodgkin's lymphoma. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing BBAP nucleic acid molecules, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a BBAP gene has been introduced or disrupted. The invention still further provides isolated BBAP proteins, fusion proteins, antigenic peptides and anti-BBAP antibodies. Diagnostic methods using compositions of the invention are also provided.
    Type: Grant
    Filed: September 19, 2001
    Date of Patent: September 26, 2006
    Assignee: Dana-Farber Cancer Institute
    Inventors: Margaret A. Shipp, Ricardo Aguiar, Liqun Gu, Kunihiko Takeyama
  • Patent number: 7113114
    Abstract: Disclosed are a method and device of converting data words into code words. This method inserts 2p p guided bits before inputting each set of data words, performs a pre-defined operation, and generates 2p data sequences with different guided bits. It chooses q data sequences from the 2p data sequences for coding, performs a run length limited (RLL) coding with a coding rate m/n, and generates q (d, k) constrained code word sequences. Finally, an optimal (d, k) constrained code word sequence is selected from the q (d, k) constrained code word sequences. The device reduces the circuitry of the RLL coding applied guided scrambling without losing the control of direct current and low frequency components.
    Type: Grant
    Filed: October 4, 2005
    Date of Patent: September 26, 2006
    Assignee: Industrial Technology Research Institute
    Inventors: Chang-Po Ma, Yung-Chi Yang, Che-Kuo Hsu
  • Patent number: 7112429
    Abstract: The invention provides a thermal tolerant mannanase that is a member of the glycoside hydrolase family. The invention further discloses this mannanase as ManA. ManA has been isolated and characterized from Acidothermus cellulolyticus. The invention further provides recombinant forms of the identified ManA. Methods of making ManA polypeptides, including fusions, variants, and derivatives, are also disclosed. Methods of using mannanase A, including for the processing of food and for use in food stuffs as bulking agents and the like, are also disclosed.
    Type: Grant
    Filed: July 28, 2001
    Date of Patent: September 26, 2006
    Assignee: Midwest Research Institute
    Inventors: Shi-You Ding, William S. Adney, Todd B. Vinzant, Michael E. Himmel
  • Patent number: 7113637
    Abstract: In order to improve pattern recognition, various kinds of transformations are performed on an input object. One or more recognition algorithms are then performed on the input object transforms in addition to the input object itself. By performing recognition algorithms on an input object and its transforms, a more comprehensive set of recognition results are generated. A final recognition decision is based upon an input object and its transforms by aggregating the recognition results.
    Type: Grant
    Filed: August 24, 2001
    Date of Patent: September 26, 2006
    Assignee: Industrial Technology Research Institute
    Inventors: Yea-Shuan Huang, Chun-Wei Hsieh
  • Patent number: 7112419
    Abstract: The invention relates to a new kind of human protein associated with hepatoma and the polynucleotide encoding the polypeptide and a process for producing the polypeptide by recombinant methods. The present invention also relates to a method of applying the polypeptide for the diagnosis and treatment of various kinds of disease, such as cancer. Further, present invention relates to the antagonist of the polypeptide and therapeutic use of the same. In addition, the invention relates to the use of the same. In addition, the invention relates to the use of polynucleotide encoding the hepatoma associated human protein.
    Type: Grant
    Filed: April 17, 2001
    Date of Patent: September 26, 2006
    Assignee: Shanghai Cancer Institute
    Inventors: Xintai Zhao, Dafang Wan, Jianren Gu
  • Patent number: 7112605
    Abstract: The invention relates to sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones compounds having formula (I) wherein R1 is selected from the group consisting of 4-methylsulfonyl, 4-aminosulfonyl, hydrogen, 2-, 3-, or 4-halogen, C1–C6-alkyl, cyclopentyl, cyclohexyl, C1–C4-alkoxy, hydroxy, cyano, nitro, amino or trifluoromethyl; R2 is selected from the group consisting of 4-methylsulfonyl, 4-aminosulfonyl, hydrogen, 2-, 3-, or 4-halogen, C1–C6-alkyl, cyclopentyl, cyclohexyl, C1–C4-alkoxy, hydroxy, cyano, nitro, amino or trifluoromethyl; and R3 is selected from the group consisting of hydrogen, methyl, ethyl, n-propyl, i-propyl, c-propyl, n-butyl, isobutyl; provided that when R1 is a methylsulfonyl or aminosulfonyl group, R2 is any group as defined above except a methylsulfonyl or aminosulfonyl group; and when R2 is a methylsulfonyl or aminosulfonyl group, R1 is any group as defined above except a methylsulfonyl or aminosulfonyl group, also to processes for the preparation of such compounds, to pharmaceutical co
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: September 26, 2006
    Assignees: Research Institute of Materia Medica Chinese Acadamy of Medical Sciences, Jiangsu Hengrui Medicine Company Ltd.
    Inventors: Zongru Guo, Guifang Cheng, Fengming Chu, Ai Ping Bai, Wen Hui Hu, Fang Shen, Guangzhong Yang, Boling Xu
  • Patent number: 7112720
    Abstract: The invention relates to a novel transformation method for plants of the genus Allium, in particular to onion plants. Plants transformed by the method are also provided. The method preferably involves an Agrobacterium tumefaciens-mediated transformation, more preferably involving immature embryos as the explant source and employing a binary vector.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: September 26, 2006
    Assignee: New Zealand Institute for Crop & Food Research Limited
    Inventors: Carolyn Elizabeth Lister, Colin Charles Eady
  • Patent number: 7112361
    Abstract: A decomposable thin film comprising a plurality of polyelectrolyte layers of alternating charge, wherein decomposition of the thin film is characterized by degradation of at least a portion of the polyelectrolyte layers.
    Type: Grant
    Filed: October 24, 2002
    Date of Patent: September 26, 2006
    Assignee: Massachusetts Institute of Technology
    Inventors: David M. Lynn, Eduardo Vazquez, Robert Langer, Paula T. Hammond
  • Patent number: 7112666
    Abstract: This invention is intended to isolate and identify a vWF-specific cleaving protease. The vWF-specific cleaving protease cleaves a bond between residues Tyr 842 and Met 843 of vWF and comprises a polypeptide chain having Leu-Leu-Val-Ala-Val as a partial sequence, and more preferably comprises a polypeptide chain having the partial N-terminal amino acid sequence of a mature protein, Ala-Ala-Gly-Gly-Ile-Leu-His-Leu-Glu-Leu-Leu-Val-Ala-Val, and having a molecular weight of 105 to 160 kDa in SDS-PAGE under reducing or non-reducing conditions. Isolation and identification of this vWF-specific cleaving protease have led to the possibility of replacement therapy for patients having diseases resulting from a deficiency of the protease, such as thrombotic thrombocytopenic purpura.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: September 26, 2006
    Assignee: Juridical Foundation the Chemo-Sero-Therapeutic Research Institute
    Inventors: Kenji Soejima, Noriko Mimura, Hiroaki Maeda, Chikateru Nozaki, Takayoshi Hamamoto, Tomohiro Nakagaki
  • Patent number: 7112939
    Abstract: The present invention relates to a mobile system and a moving method of the mobile system. According to the present invention, a natural period is measured from a vibration component signal generated by a force due to acceleration/deceleration of wheels, and the mobile system moves by applying an acceleration profile containing an acceleration period or a deceleration period based on the natural period. Therefore, the acceleration profile based on the natural period is applied such that vibration that is visible to a user is not generated during acceleration and deceleration of the mobile system. As a result, quality of the mobile system is improved.
    Type: Grant
    Filed: November 29, 2005
    Date of Patent: September 26, 2006
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Eul Gyoon Lim, Dae-Hwan Hwang
  • Patent number: 7112325
    Abstract: The invention provides a novel calcium-independent cytosolic phospholipase A2/B enzyme, polynucleotides encoding such enzyme, antibodies to such enzyme, and methods for screening unknown compounds for anti-inflammatory activity mediated by the arachidonic acid cascade.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: September 26, 2006
    Assignee: Genetics Institute, LLC
    Inventors: Simon Jones, Jin Tang
  • Patent number: 7113690
    Abstract: An anti-counterfeit method and system by using a nano metal grating, wherein an object to be recognized is formed with the nano metal grating. During the recognition process, an incidental light is applied on the metal grating. In response to the incidental light, the metal grating has its specific optical incidence and reflection characteristics. The object is then identified whether it is genuine or fake by observing the refraction light passing through and reflection light reflected from the metal grating. Further, the incident light beam can be polarized to generate polarized light beams and then irradiated on the metal grating, whereafter the recognition of the object is performed by observing the reflection and refraction lights of the irradiated polarized light beam. The recognition further can be accomplished by rotating the metal grating, thus the intensity of the refraction and reflection lights will accordingly be changed, thereby identifying the object.
    Type: Grant
    Filed: May 4, 2004
    Date of Patent: September 26, 2006
    Assignee: Industrial Technology Research Institute
    Inventors: Pong Lai, Ying-Tsung Lu, Ching-Chin Wu
  • Patent number: 7113388
    Abstract: In accordance with the invention there is provided a semiconductor capacitor having a first semiconductor layer which forms a first capacitor electrode and which includes silicon, a second capacitor electrode and a capacitor dielectric including praseodymium oxide between the capacitor electrodes, in which provided between the capacitor dielectric including praseodymium oxide and at least the first semiconductor layer including silicon is a first thin intermediate layer representing a diffusion barrier for oxygen. In particular the thin intermediate layer can include oxynitride.
    Type: Grant
    Filed: April 23, 2003
    Date of Patent: September 26, 2006
    Assignees: IHP GmbH- Innovations for High Performance, Microelectronics/Institute Fur Innovative Mikroelektronik
    Inventor: Hans-Joachim Müssig
  • Patent number: 7112723
    Abstract: A globulin-2 regulatory region is shown, which provides improved seed preferred, and particularly embryo preferred expression in plants. Methods of use are also shown in preferentially expressing a heterologous protein to the embryo tissue of a plant. The sequence is particularly useful in expression of heterologous proteins to the embryo of monocotyledonous plants, particularly cereals, and maize.
    Type: Grant
    Filed: July 27, 2005
    Date of Patent: September 26, 2006
    Assignee: Applied Biotechnology Institute
    Inventors: Stephen Streatfield, Robert Love, Jeff Bray
  • Patent number: 7113461
    Abstract: A circuit for tracking error signal detection on an optical storage medium, which has a plurality of digitizers, a plurality of logic comparators and a difference amplifier, is disclosed. The circuit involves summing the signals to be compared and obtaining a delay signal via a delayer. Therefore, the phase difference of the signals is detected via the delay signal to obtain the tracking error signal of the optical storage medium.
    Type: Grant
    Filed: June 24, 2003
    Date of Patent: September 26, 2006
    Assignee: Industrial Technology Research Institute
    Inventors: Chih-Chien Huang, Yuh Cheng, Nai-Heng Tseng
  • Patent number: 7112569
    Abstract: The present invention relates to a novel protein inhibiting ? amyloid aggregation and a strain producing the protein, more precisely, to a novel protein inhibiting ? amyloid aggregation, a gene coding the protein, a Streptomyces sp. strain producing the protein and a therapeutic agent for neurodegenerative disorders containing the protein as an effective ingredient. The therapeutic agent of the present invention containing the protein inhibiting ? amyloid aggregation as an effective ingredient can be effectively used for the prevention and the treatment of neurodegenerative disorders like Alzheimer's disease.
    Type: Grant
    Filed: July 2, 2004
    Date of Patent: September 26, 2006
    Assignee: National Institute of Health
    Inventors: Sangmee Ahn Jo, Inho Jo, Ho Jeong Kwon, Chang Jin Kim, Jeong Eun Park
  • Patent number: 7112615
    Abstract: Methods and systems are disclosed for fabricating ultra-low dielectric constant porous materials. In one aspect of the invention, a method for making porous low-k films is disclosed. The method uses polymer based porogens as sacrificial templates around which a chemical vapor deposition (CVD) or plasma enhanced chemical vapor deposition (PECVD) deposited matrix is formed. Upon pyrolysis, the porogens decompose resulting in a porous ultra-low dielectric material. This method can be used, for example, to produce porous organosilicate glass (OSG) materials, ultra-low dielectric nanoporous materials, porous ceramics, porous scaffolds, and/or porous metals. Various uses and embodiments of the methods and systems of this invention are disclosed.
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: September 26, 2006
    Assignee: Massachusetts Institute of Technology
    Inventors: Karen K. Gleason, Qingguo Wu, April Ross
  • Patent number: 7112423
    Abstract: The present invention provides methods and kits for amplifying target nucleic acids (including whole genomes) using nicking agents. In certain aspects, the amplification does not require the use of any external oligonucleotide primers that are capable of annealing to a portion of the target nucleic acid. This invention is useful in many areas such as genetic disease diagnoses, forensic analyses and palcoarcheological studies.
    Type: Grant
    Filed: July 15, 2002
    Date of Patent: September 26, 2006
    Assignee: Keck Graduate Institute
    Inventors: Jeffrey Van Ness, David J Galas, Lori K Van Ness
  • Patent number: RE39308
    Abstract: A 3,5-dioxa-12-azawurtzitane compound represented by the formula (I) shown in the specification. The dioxaazawurtzitane compound may be prepared by reacting an amino acid, an oligo- or polypeptide or a polyamino acid with a trialdehyde represented by formula (II) shown in the specification.
    Type: Grant
    Filed: May 7, 2004
    Date of Patent: September 26, 2006
    Assignees: National Institute of Science and Technology
    Inventors: Hiroshi Izumi, Shigeru Futamura