Patents Assigned to INSTITUTE
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Publication number: 20210070657Abstract: Provided are a textile reinforced cement composite for suppressing occurrence of slipping and a crack and a manufacturing method thereof.Type: ApplicationFiled: December 3, 2019Publication date: March 11, 2021Applicant: KOREA INSTITUTE OF CIVIL ENGINEERING AND BUILDING TECHNOLOGYInventors: Gum Sung RYU, Kyung Taek KOH, Hyeong Yeol KIM, Gi Hong AN, Dong Woo SEO, Seung Seop JIN
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Publication number: 20210071158Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.Type: ApplicationFiled: April 11, 2018Publication date: March 11, 2021Applicants: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Feng Zhang, David Benjamin Turitz Cox
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Publication number: 20210074872Abstract: A visibly transparent luminescent solar concentrator (LSC) is disclosed. The LSC includes a transparent substrate having at least one edge surface. A dye layer is coupled to the substrate, the dye layer having a peak absorption wavelength outside the visible band, the dye layer being configured to re-emit light at a peak emission wavelength outside the visible band, at least a portion of the re-emitted light being waveguided to the edge surface of the substrate. A photovoltaic device is coupled to the edge surface of the transparent substrate, the photovoltaic device being configured to absorb light at the peak emission wavelength and generate electrical energy.Type: ApplicationFiled: November 20, 2020Publication date: March 11, 2021Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Richard Royal Lunt, Vladimir Bulovic, Biles Clark Barr
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Publication number: 20210069177Abstract: Disclosed are a method for destroying cellular mechanical homeostasis and the use thereof, especially disclosed is a method for destroying cellular mechanical homeostasis by using a Myosin inhibitor thereby leading to cell softening and reduction of fibrosis in tissues and organs. Also disclosed are a method for promoting regeneration and repair of tissues and organs and the use thereof. The Myosin inhibitor can destroy the homeostasis of the cellular mechanical stress system, reduce the rigidity of tissues and organs in a pathological state, and stimulate stress and regeneration reactions similar to those in the regeneration processes in lower organisms; and can use the characteristics to greatly inhibit fibrosis during the organ damage and to promote the regeneration and repair of tissues and organs, and meanwhile can use stress response to greatly improve the ability of cellular genetic repair. The Myosin inhibitor is preferably (?)-Blebbistatin, or a derivative thereof (?)-Blebbistatin O-Benzoate.Type: ApplicationFiled: January 29, 2019Publication date: March 11, 2021Applicant: INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCESInventors: Qi ZHOU, Wei Ll, Zhengquan HE, Liu WANG
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Publication number: 20210071163Abstract: Embodiments disclosed include engineered CRISPR-Cas effector proteins that comprise at least one modification compared to an unmodified CRISPR-Cas effector protein that enhances binding of the CRISPR complex to the binding site and/or alters editing preference as compared to wild type. In certain embodiments, the CRISPR-Cas effector protein is C2c1. Embodiments also include viral vectors for delivery of CRISPR-Cas effector proteins, including C2c1. For example, the vectors may be designed to allow packaging of the CRISPR-Cas effector protein within a single vector. In another aspect delivery vectors, constructs, and methods of delivering larger genes for systemic delivery.Type: ApplicationFiled: December 21, 2018Publication date: March 11, 2021Applicants: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Feng Zhang, Bernd Zetsche
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Publication number: 20210070947Abstract: An aqueous polymer is provided, which is formed by neutralizing a copolymer modified by polyalkylene glycol with ammonia, primary amine, secondary amine, or a combination thereof, wherein the copolymer is copolymerized from an anhydride monomer with a double bond, a monomer with a double bond, and an initiator. The aqueous polymer can be mixed and dispersed with water and pigment powder to form a dispersion. The dispersion can be mixed with binder to form an aqueous paint.Type: ApplicationFiled: December 26, 2019Publication date: March 11, 2021Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Cha-Wen CHANG, Ruo-Han YU, Shinn-Jen CHANG, Yu-Hui CHEN, Jen-Yu CHEN
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Publication number: 20210075053Abstract: The present disclosure relates to a cathode active material for a sodium ion secondary battery having high reversible capacity and excellent cycle characteristics, and a method for preparing the same. The cathode active material for a sodium ion secondary battery shows high reversible capacity and excellent cycle characteristics, when it is applied to a secondary battery. Therefore, when the cathode active material is used for manufacturing a cathode for a sodium ion secondary battery and the cathode is applied to a sodium ion secondary battery, the battery can substitute for the conventional expensive lithium ion secondary battery and can be applied to various industrial fields.Type: ApplicationFiled: December 23, 2019Publication date: March 11, 2021Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Kyung Yoon CHUNG, Dong Hyun KIM, Juhyeon AHN, Jaeho PARK, Ji-Young KIM, Min Kyung CHO, Byung Won CHO, Hun-Gi JUNG, Minah LEE, Seungho YU, Hyungseok KIM
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Publication number: 20210074867Abstract: A high absorption photovoltaic material and method of making the material for use in a solar cell are disclosed. The photovoltaic material includes a surface modified with a layer of repeating photonic crystal structures. The photonic crystal structures are approximately inverse conically shaped and have a curved sidewall that has an approximately Gaussian shape. The photonic crystal structures generally have a high vertical depth and sidewall angle. The structures also have a gradient refractive index profile and exhibit the parallel-to-interface refraction light trapping effect. An anti-reflective coating is disposed over the photonic crystal structure layer. The photovoltaic material exhibits near unity light absorption over a broad range of visible and near infrared wavelengths and incidence angles, even at reduced thicknesses.Type: ApplicationFiled: November 18, 2020Publication date: March 11, 2021Applicant: RENSSELAER POLYTECHNIC INSTITUTEInventors: Ping KUANG, Shawn Yu LIN, Anthony POST, Sajeev Oommen JOHN, Sergey Leonidovich EYDERMAN, Mei-Li HSIEH
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Publication number: 20210068858Abstract: Provided is a forceps driving apparatus including a body, a gripper installed to be received in the body and formed to be open and closed, an opening and closing member rotatably installed in the body to press or release two sides of the gripper by rotation, an elastic member connected to one side of the opening and closing member to provide an elastic force to the opening and closing member, an actuator connected to the other side of the opening and closing member to rotate the opening and closing member by contraction or extension, and a force sensing module to measure a gripping force of the gripper during the rotation of the opening and closing member.Type: ApplicationFiled: August 28, 2020Publication date: March 11, 2021Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Donghyun HWANG, Sungwoo PARK, Namseon JANG, Yong Seok IHN, Jinwoo JEONG, Keehoon KIM, Sang Rok OH, Sungwook YANG, Sehyuk YIM
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Publication number: 20210071240Abstract: The present disclosure relates to compositions and methods for detection of single-stranded breaks (SSBs) in dsDNA, including in genomic DNA. Measurement of the precise location of SSB damage in DNA, e.g.Type: ApplicationFiled: April 18, 2019Publication date: March 11, 2021Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE BROAD INSTITUTE, INC.Inventors: Sarah DiIorio, Joshua Elacqua, Arnaud Gutierrez, Navpreet Ranu, Paul Blainey
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Publication number: 20210075040Abstract: A hierarchical fault classification method for a fuel cell system, a multi-stage fault diagnosis method therefor, and a fault diagnosis device therefor are disclosed. The fuel cell system is divided into a subsystem, a component, and an element step by step. The multi-stage fault diagnosis method includes detecting a subsystem, a fault of which occurs, in the fuel cell system composed of a plurality of subsystems and detecting an upper-level component, which causes the fault, among upper-level components included in the subsystem, the fault of which occurs, using measurement data and a control signal.Type: ApplicationFiled: January 30, 2020Publication date: March 11, 2021Applicant: KOREA INSTITUTE OF ENERGY RESEARCHInventors: Won Yong LEE, Hwan Yeong OH, Min Jin KIM, Seok Hee PARK, Gu Gon PARK, Tae Hyun YANG, Sung Dae YIM, Young Jun SOHN, Byung Chan BAE, Seung Gon KIM, Dong Won SHIN, Seung Hee WOO, So Jeong LEE, Hye Jin LEE, Yoon Young CHOI
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Publication number: 20210075023Abstract: Flexible air-breathing microscale fuel cells are produced using ion exchange polymer membranes without silicon substrates or other rigid components. The microscale fuel cells provide long-life energy supply sources in portable electronics due to reduced volume, high energy density, and low cost. More particularly, the microscale fuel cell has a direct hydrogen flow-through porous anode electrode with a pair of air-breathing cathodes.Type: ApplicationFiled: November 20, 2020Publication date: March 11, 2021Applicant: THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGYInventors: Ronald Besser, Seyed Reza Mahmoodi
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Publication number: 20210070925Abstract: An aqueous polymer is formed by neutralizing a copolymer modified by polyalkylene glycol with ammonia, primary amine, secondary amine, inorganic base, or a combination thereof, wherein the copolymer is copolymerized from an anhydride monomer with a double bond, a monomer with a double bond, and an initiator. The aqueous polymer can be mixed and dispersed with water and pigment powder to form a dispersion. The dispersion can be mixed with binder to form an aqueous paint.Type: ApplicationFiled: September 3, 2020Publication date: March 11, 2021Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Cha-Wen CHANG, Ruo-Han YU, Shinn-Jen CHANG, Yu-Hui CHEN, Jen-Yu CHEN
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Publication number: 20210069914Abstract: A robotic platform manipulating peripheral nerve system includes a manipulator and a recorder. The manipulator includes a rotating guide, a plurality of rotating movers and a plurality of manipulating units. The rotating guide has an opening portion through which the recorder records, and has a guide rail at a side. The rotating movers are combined with the rotating guide and move along the guide rail. The manipulating units are respectively fixed to the rotating movers, and a manipulating part performs the operation being connected to an end of each of the manipulating units.Type: ApplicationFiled: September 10, 2019Publication date: March 11, 2021Applicants: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITYInventors: Keehoon KIM, Yong Seok Ihn, Donghyun Hwang, Sehyuk Yim, Sang Rok Oh, Jinwoo Jeong
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Patent number: 10941386Abstract: A modified endoinulinase is provided, comprising modified wild-type T. purpuregenus endoinulinase, or a functional fragment thereof, in which an amino acid residue at each one of one or more positions corresponding to 128, 316, 344, 350 or 504 of wild-type T. purpuregenus endoinulinase is substituted, wherein: (i) a tyrosine residue corresponding to Y128 is substituted with H, K or R; a glutamate residue corresponding to E344 is substituted with K, H or R; and a threonine residue corresponding to T504 is substituted with M, S or Y; and optionally an alanine residue corresponding to A316 is substituted with T, S, C or M; (ii) a tyrosine residue corresponding to Y128 is substituted with H, K or R; a glutamate residue corresponding to E344 is substituted with K, H or R; a threonine residue corresponding to T504 is substituted with M, S or Y; and a glutamine residue corresponding to Q350 is substituted with L, G, A, V or I; or (iii) a tyrosine residue corresponding to Y128 is substituted with H, K or R.Type: GrantFiled: August 7, 2018Date of Patent: March 9, 2021Assignee: MIGAL GALILEE RESEARCH INSTITUTE LTD.Inventors: Itamar Yadid, Rami Cohen, Livnat Afriat-Jurnou
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Patent number: 10941072Abstract: The disclosed fluorophosphate glasses for an active device include: a metaphosphate composition including Al(PO3)3; a fluoride composition including BaF2 and SrF2; and a dopant composed of ErF3 and YbF3, and have thermal and mechanical properties to be able to be used as a glass base material for an active device (e.g., optical fiber laser), have a high emission cross-section characteristic, have a reinforced upconversion and downconversion emission characteristic, and have high sensitivity S in a cryogenic environment.Type: GrantFiled: May 19, 2018Date of Patent: March 9, 2021Assignee: KOREA PHOTONICS TECHNOLOGY INSTITUTEInventors: Ju Hyeon Choi, Jung Whan In, Yeon Hwang, Young Bok Kim
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Patent number: 10940864Abstract: Control commands in a system and method for autonomously driving a vehicle or partially autonomously driving a vehicle are generated on the basis of an environment representation, which is generated from sensor signal of a sensing means. The environment representation where ambiguous objects are identified is such that information obtained from the driver of the vehicle are added. The system generates an information request. Additional information is extracted and accumulated in the environment representation map. Traffic is then determined and suitable control signals for the vehicles are generated. In case no ambiguous objects are included in the environment representation but the system is not capable of deciding on traffic, the driver is asked to disambiguate the situation or to instruct on dealing with the traffic.Type: GrantFiled: August 10, 2016Date of Patent: March 9, 2021Assignee: HONDA RESEARCH INSTITUTE EUROPE GMBHInventors: Martin Heckmann, Heiko Wersing
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Patent number: 10943561Abstract: The image data display system according to the present invention makes it possible to comprehend a global distribution of measurement values and a change in details of the measurement values simultaneously. In the present invention, a color information conversion unit converts the measurement values to color information for representing the global distribution of the measurement values. A detail extraction unit extracts detail information of the measurement values from the measurement values. A detail adjustment unit adjusts the strength of detail information and generates adjusted detail information. A color information adding unit adds color information on the basis of the adjusted detail information.Type: GrantFiled: September 7, 2017Date of Patent: March 9, 2021Assignees: NEC Corporation, TOKYO INSTITUTE OF TECHNOLOGYInventors: Takashi Shibata, Masayuki Tanaka, Masatoshi Okutomi
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Patent number: 10940462Abstract: A vanadium-based catalyst comprises an active phase carried on a carrier. The active phase comprises vanadium oxide, potassium sulfate, sodium sulfate, and assistants. The carrier comprises ultra-large-pore silicon dioxide and diatomite, the average pore size of the ultra-large-pore silicon dioxide ranges from 100 nm to 500 nm, and the diatomite is a refined diatomite having a silicon dioxide content of higher than 85% after refinement. The preparation method for the vanadium-based catalyst comprises: 1) mixing potassium vanadium and potassium hydroxide, and allowing a prepared mixed solution and sulfuric acid to carry out a neutralization reaction; and 2) mixing a neutralization reaction product in step 1) with the carrier and sodium sulfate, and carrying out rolling, band extrusion, drying and roasting to prepare the vanadium-based catalyst, assistant compounds being added in step 1) and/or step 2).Type: GrantFiled: June 13, 2017Date of Patent: March 9, 2021Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, SINOPEC NANJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTDInventors: Xianguo Tian, Shixin Wei, Tianlei Dong, Huiqin Yin, Tianming Xie, Jian He
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Patent number: 10940198Abstract: The present invention relates to a herpes zoster vaccine composition, which comprises glycoprotein E of Varicella zoster virus, a glucopyranosyl lipid adjuvant, and a metabolic oil, and selectively increases a cell-mediated immune reaction without having disadvantages of attenuated live vaccines, thereby exhibit high safety and a high preventive effect against herpes zoster.Type: GrantFiled: December 20, 2017Date of Patent: March 9, 2021Assignees: MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH, INFECTIOUS DISEASE RESEARCH INSTITUTEInventors: Hyo Jung Nam, Eun Mi Kim, Duck Hyang Shin, Steven G. Reed, Kang Il Yoo, Sung Jun Hong