Patents Assigned to INSTITUTE
  • Publication number: 20230029309
    Abstract: Titanium-containing alloys are generally described. The titanium-containing alloys are, according to certain embodiments, nanocrystalline. According to certain embodiments, the titanium-containing alloys have high relative densities. The titanium-containing alloys can be relatively stable, according to certain embodiments. Inventive methods for making titanium-containing alloys are also described herein. The inventive methods for making titanium-containing alloys can involve, according to certain embodiments, sintering nanocrystalline particulates comprising titanium and at least one other metal to form a titanium-containing nanocrystalline alloy.
    Type: Application
    Filed: April 29, 2022
    Publication date: January 26, 2023
    Applicant: Massachusetts Institute of Technology
    Inventors: Kathrin Graetz, Christopher A. Schuh
  • Publication number: 20230022757
    Abstract: The disclosure relates to modified vaccinia virus vectors derived from the Copenhagen strain of vaccinia virus, as well as methods of using the same for the treatment of various cancers. The disclosure provides modified Copenhagen-derived vaccinia virus vectors that exhibit various beneficial therapeutic activities, including enhanced oncolytic activity, spread of infection, immune evasion, tumor persistence, capacity for incorporation of exogenous DNA sequences, amenability for large scale manufacturing, and safety.
    Type: Application
    Filed: March 14, 2022
    Publication date: January 26, 2023
    Applicant: OTTAWA HOSPITAL RESEARCH INSTITUTE
    Inventors: John C. Bell, Fabrice Le Boeuf, Michael S. Huh, Matthew Y. Tang, Brian Andrew Keller, Adrian Pelin
  • Publication number: 20230025214
    Abstract: A biometric information measurement system and method are disclosed. A biometric information measurement system according to an embodiment of the present invention may comprise an implant device that is inserted into the human body so as to measure biometric information and an external device that transmits a signal to the implantable device while sweeping a frequency.
    Type: Application
    Filed: September 30, 2022
    Publication date: January 26, 2023
    Applicant: UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY)
    Inventor: Franklin Don Bien
  • Publication number: 20230025974
    Abstract: Smart membranes (14) are integrated into a small, unmanned surface vessel (20) to enable the efficient, automated cleanup of oil spills. Such a vessel (20) has the potential to provide a low-cost, modular solution for day-to-day oil-spill cleanup operations, especially in confined aquatic areas, such as under piers and in the small spaces between marine vessels and piers. The smart membranes (14) are provided on the surface of a conveyor belt (34) that circulates the membranes (14) through the surrounding body of water (10) for oil collection, as well as through an internal reduction chamber (22) of the vessel (20) for oil release. The smart membranes (14) are adapted to attract and repel oil (12) in response to low-voltage commands applied across the conveyor belt (34), using a process that is repeatable for a number of cycles, offering high efficiency and long durability (FIG. 5).
    Type: Application
    Filed: August 4, 2022
    Publication date: January 26, 2023
    Applicant: THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY
    Inventors: Eui-Hyeok Yang, Jian Xu, Wei Xu, Brendan Englot, Chang-Hwan Choi
  • Publication number: 20230027346
    Abstract: The application relates to substituted hydantoinamides of formula (I) as ADAMTS7 antagonists, to processes for their preparation, their use alone or in combination for the treatment or prophylaxis of diseases, in particular of cardiovascular diseases, including atherosclerosis, coronary artery disease (CAD), peripheral vascular disease (PAD), arterial occlusive disease or restenosis after angioplasty. R1 is hydrogen, alkyl, cycloalkyl, heterocycloalkyl, heteroaryl or phenyl; R2 is hydrogen, cyano, halogen, alkylsulfonyl, alkyl, cycloalkyl or alkoxy; R3, R4, R5, R6, R7 and R8 are independently hydrogen, halogen, alkyl or alkoxy; most groups being optionally substituted; with the proviso that at least one of R2, R3, R4 is H; X1, X2, X3, X4, X5 and X6 are independently N or C; with the proviso that in each ring maximal one X is N.
    Type: Application
    Filed: November 12, 2020
    Publication date: January 26, 2023
    Applicants: BAYER AKTIENGESELLSCHAFT, THE BROAD INSTITUTE, INC.
    Inventors: Daniel MEIBOM, Yolanda CANCHO GRANDE, Pierre WASNAIRE, Sarah Anna Liesa JOHANNES, Kristin BEYER, Till FREUDENBERGER, Damian BROCKSCHNIEDER, Dmitry ZUBOV, Dzianis MENSHYKAU, Tanja KRAINZ, Bryan MACDONALD, Yi XING, Nadine ELOWE, Guzman SANCHEZ
  • Publication number: 20230027892
    Abstract: Provided is an electronic device including a plurality of substrate electrodes on a substrate, the substrate electrodes including initial electrodes and spare electrodes, a bonding material covering the initial electrodes and the spare electrodes, module structures respectively provided on first initial electrodes of the initial electrodes, and solders between each of the first initial electrodes and each of the module structures, wherein the spare electrodes include second spare electrodes, wherein the module structures are not provided on the second spare electrodes, wherein the bonding material on the first initial electrodes is harder than the bonding material on the second spare electrodes.
    Type: Application
    Filed: July 14, 2022
    Publication date: January 26, 2023
    Applicant: Electronics and Telecommunications Research Institute
    Inventors: KWANG-SEONG CHOI, Yong-Sung EOM, Jiho JOO, GWANG-MUN CHOI, Seok-Hwan MOON, Ho-Gyeong YUN, CHANMI LEE, Ki-Seok JANG
  • Publication number: 20230027659
    Abstract: An own-position estimating device for estimating an own-position of a moving body by matching a feature extracted from an acquired image with a database in which position information and the feature are associated with each other in advance, includes an evaluation result acquiring unit acquiring an evaluation result obtained by evaluating matching eligibility of the feature in the database, and a processing unit processing the database on the basis of the evaluation result acquired by the evaluation result acquiring unit.
    Type: Application
    Filed: December 15, 2020
    Publication date: January 26, 2023
    Applicants: KABUSHIKI KAISHA TOYOTA JIDOSHOKKI, National Institute of advanced industrial Science and Technology
    Inventors: Tatsuya KOMURO, Norihiko KATO, Atsuhiko BANNO, Masashi YOKOZUKA, Hiromu ONDA
  • Publication number: 20230024744
    Abstract: A method and a system for optimizing problem-solving based on probabilistic bit circuits are provided. The method includes: performing a modeling transformation on an objective problem to obtain a corresponding Hamiltonian relationship; obtaining a column Hamiltonian of said probabilistic bit circuit based on said Hamiltonian relationship; and performing parallel annealing iterations on multicolumn Hamiltonian based on row-flipping operations on said probabilistic bit circuits to obtain an updated probabilistic bit configuration, so as to achieve optimization of said problem.
    Type: Application
    Filed: July 14, 2022
    Publication date: January 26, 2023
    Applicant: Institute of Semiconductors, Chinese Academy of Sciences
    Inventors: Kaiyou Wang, Xiukai Lan, Yucai Li, Yi Cao
  • Publication number: 20230021848
    Abstract: Deformable sensors and methods for magnetically modifying membrane stiffness are provided. A deformable sensor may include a membrane coupled to a housing to form a sensor cavity. The deformable sensor may further include a first magnet located on an inner surface of the membrane in the sensor cavity. The deformable sensor may additionally include a magnetic object located at a base within the sensor cavity. The magnetic object may be configured to modifiably repel the first magnet and modify stiffness of the deformable sensor based upon the modified repulsion.
    Type: Application
    Filed: July 20, 2021
    Publication date: January 26, 2023
    Applicant: Toyota Research Institute, Inc.
    Inventors: Manuel L. Kuehner, Naveen Suresh Kuppuswamy
  • Publication number: 20230025008
    Abstract: The present invention relates to a novel method for preparing lithium oxide. In the present invention, the particle size and shape of lithium oxide may be controlled during the preparing process. In addition, the present invention relates to lithium oxide with controlled particle size and shape prepared by this preparing method.
    Type: Application
    Filed: December 7, 2020
    Publication date: January 26, 2023
    Applicants: POSCO, RESEARCH INSTITUTE OF INDUSTRIAL SCIENCE & TECHNOLOGY
    Inventors: Jae Myung LEE, Jun-Kyu AHN, Woo Chul JUNG, Kee Uek JEUNG, Jung Kwan PARK, Sang Won KIM
  • Publication number: 20230028893
    Abstract: The present invention relates to a three-dimensional structure electrode, a method for manufacturing same, and an electrochemical element including the electrode. The present invention is characterized by comprising: (a) an upper conductive layer and a lower conductive layer which have a structure constituting an assembly within which a conductive material and a porous nonwoven fabric including a plurality of polymeric fibers are three-dimensionally connected in an irregular and continuous manner, thereby forming a mutually connected porous structure; and (b) an active material layer forming the same assembly structure as the conductive layers and forming a three-dimensionally filled structure in which electrode active material particles are uniformly filled inside the mutually connected porous structure formed in the assembly structure, wherein the active material layer is formed between the upper conductive layer and the lower conductive layer.
    Type: Application
    Filed: September 28, 2022
    Publication date: January 26, 2023
    Applicants: UNIST (Ulsan National Institute of Science and Technology), LG Energy Solution, Ltd.
    Inventors: In Sung Uhm, Sang Young Lee, Yo Han Kwon, Ju Myung Kim, Joon Won Lim, Jae Hyun Lee, Je Young Kim, Seong Hyeok Kim
  • Publication number: 20230022775
    Abstract: This disclosure provides riboregulators specific for particular viruses or for particular human transcription factors. The viral-specific riboregulators may be used to detect the presence of the particular virus, and this may enable diagnosis of an infection. The transcription factor specific riboregulators may be used to detect the presence and/or measure the level of the particular transcription factor, and this may enable diagnosis or prognosis of a particular condition such as cancer.
    Type: Application
    Filed: December 11, 2020
    Publication date: January 26, 2023
    Applicants: President and Fellows of Harvard College, Massachusetts Institute of Technology
    Inventors: Luis Ruben Soenksen Martinez, Nicolaas Angenent-Mari, Alexander S. Garruss, James J. Collins, George M. Church, Katherine Collins, Diogo M. Camacho
  • Publication number: 20230025634
    Abstract: Provided is a 5G dual port beamforming antenna. The beamforming antenna according to an embodiment of the present disclosure includes a plurality of patch antennas, and the patch antenna includes: a first patch positioned on an upper portion; a second patch positioned on a left side under the first patch and having a plurality of feeding ports formed thereon; a third patch positioned on an upper portion of a right side of the second patch; and a fourth patch positioned on a lower portion of the right side of the second patch. Accordingly, 3D wide angle beamforming is possible in an antenna to be used in 5G mobile communication systems, military radar systems, etc.
    Type: Application
    Filed: December 22, 2020
    Publication date: January 26, 2023
    Applicant: Korea Electronics Technology Institute
    Inventors: Ki Jin KIM, Kwang Ho AHN, Soo Chang CHAE
  • Publication number: 20230028358
    Abstract: Two inverters (10) provided at respective both ends of open-end windings (8) are appropriately controlled. As control regions (R) of a rotating electrical machine (80), a first speed region (VR1) and a second speed region (VR2) in which the rotational speed of the rotating electrical machine (80) is higher than in the first speed region (VR1) for the same torque are set, and in the second speed region (VR2), a rotating electrical machine control device (1) controls both inverters (10), a first inverter (11) and a second inverter (12), by mixed pulse width modulation control in which control is performed such that a plurality of pulses with different patterns are outputted during a first period (T1) which is a half cycle of electrical angle, and an inactive state continues during a second period (T2) which is the other half cycle.
    Type: Application
    Filed: September 29, 2020
    Publication date: January 26, 2023
    Applicants: AISIN CORPORATION, NAGOYA INSTITUTE OF TECHNOLOGY
    Inventors: Subrata SAHA, Hiroki IWAI, Takashi KOSAKA, Hiroak MATSUMORI, Naoto SAITO, Yoshinobu ITO, Isao FUJIWARA
  • Publication number: 20230026961
    Abstract: In one embodiment, there is provided an apparatus for low-dimensional manifold constrained disentanglement for metal artifact reduction (MAR) in computed tomography (CT) images. The apparatus includes a patch set construction module, a manifold dimensionality module, and a training module. The patch set construction module is configured to construct a patch set based, at least in part on training data. The manifold dimensionality module is configured to determine a dimensionality of a manifold. The training module is configured to optimize a combination loss function comprising a network loss function and the manifold dimensionality. The optimizing the combination loss function includes optimizing at least one network parameter.
    Type: Application
    Filed: July 7, 2022
    Publication date: January 26, 2023
    Applicant: Rensselaer Polytechnic Institute
    Inventors: Ge Wang, Chuang Niu, Wenxiang Cong
  • Publication number: 20230026983
    Abstract: Polymeric mist control materials, methods of forming polymeric mist control materials, and methods of using such materials for mist control are provided. The polymeric mist control additives are formed of molecules comprised predominantly of monomers that confer high solubility in fuel and include associative groups that attract each other in donor-acceptor manner, and are incorporated such that multiple associative groups are in close proximity (“clusters”), such that the clusters are separated by very long non-associative sequences.
    Type: Application
    Filed: March 7, 2022
    Publication date: January 26, 2023
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Ming-Hsin WEI, Julia A. KORNFIELD, Ralph Leonard Ameri DAVID
  • Publication number: 20230028239
    Abstract: Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are provided. These methods may be performed without forming embryoid bodies or clusters of pluripotent stem cells, and may be performed without the use of stromal inducer cells. Additionally, the yield and/or purity can be greater than has been reported for prior methods of producing platelets from pluripotent stem cells. Also provided are compositions and pharmaceutical preparations comprising platelets, preferably produced from pluripotent stem cells.
    Type: Application
    Filed: May 24, 2022
    Publication date: January 26, 2023
    Applicant: Astellas Institute for Regenerative Medicine
    Inventors: Qiang Feng, Shi-Jiang Lu, Robert P. Lanza
  • Publication number: 20230026024
    Abstract: Proposed is a two-pot-two-step simultaneous conversion system for carbon dioxide and a hydrocarbon containing at least one hydroxy group and a method thereof. The system integrates a process of producing a metal salt that is a dehydrogenated form of the hydrocarbon, hydrogen, and water by reacting a hydrocarbon containing at least one hydroxy group in the presence of water and a metal oxalate, and a process of converting carbon dioxide or carbon dioxide-derived carbonate into formate by hydrogenation, thereby increasing energy efficiency while maintaining a higher hydrocarbon conversion rate and a higher carbon dioxide conversion rate than the one-pot conversion system for hydrocarbon and carbon dioxide.
    Type: Application
    Filed: July 6, 2022
    Publication date: January 26, 2023
    Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Young Kyu HWANG, Changho YOO, Dong Won HWANG, Do-Young HONG, Jaedeuk PARK, In Hyoup SONG, Maeum LEE, Kyung-Ryul OH, Anil Haribhau VALEKAR
  • Publication number: 20230028590
    Abstract: An ALS treatment method includes administering to an ALS patient an inhibitor for a target A or a promoter for a target B. The target A is one or more genes selected from the genes in Table 1-1 or a protein encoded by the gene, and the inhibitor for the target A is a substance that inhibits expression of the gene, or a substance that inhibits a function of the protein encoded by the gene. The target B is one or more genes selected from the genes in Table 1-2 or a protein encoded by the gene, and the promoter for the target B is a substance that promotes the expression of the gene, or a substance that promotes a function of the protein encoded by the gene.
    Type: Application
    Filed: June 30, 2022
    Publication date: January 26, 2023
    Applicants: MITSUBISHI TANABE PHARMA CORPORATION, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Manolis KELLIS, Sergio Sebastian PINEDA, Myriam HEIMAN, Makoto TAMURA
  • Publication number: 20230025039
    Abstract: The present disclosure provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides Cas proteins and their use in modifying target sequences.
    Type: Application
    Filed: September 18, 2020
    Publication date: January 26, 2023
    Applicants: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Feng Zhang, Han Altae-Tran, Soumya Kannan