Patents Assigned to INSTITUTE
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Patent number: 11458129Abstract: In some embodiments, methods of inhibiting, ameliorating, reducing the severity of, treating, reducing the likelihood of, or preventing social isolation stress or symptoms thereof in a subject in need thereof are described. In some embodiments, methods of determining a risk of social isolation stress in a subject are described.Type: GrantFiled: November 1, 2018Date of Patent: October 4, 2022Assignee: California Institute of TechnologyInventors: David J. Anderson, Moriel Zelikowsky, Andrea Choe
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Patent number: 11458158Abstract: Described herein are compounds and compositions characterized, in certain embodiments, by conjugation of various groups, such as lipophilic groups, to an amino or amide group of an amino acid, a linear or cyclic peptide, a linear or cyclic polypeptide, or structural isomer thereof, to provide compounds of the present invention, collectively referred to herein as “APPLs”. Such APPLs are deemed useful for a variety of applications, such as, for example, improved nucleotide delivery. Exemplary APPLs include, but are not limited to, compounds of Formula (I), (II), (III), (IV), (V), and (VI), and salts thereof, as described herein: wherein m, n, p, R?, R1, R2, R3, R4, R5, R8, Z, W, Y, and Z are as defined herein.Type: GrantFiled: May 5, 2020Date of Patent: October 4, 2022Assignee: Massachusetts Institute of TechnologyInventors: Yizhou Dong, Kevin Thomas Love, Robert S. Langer, Daniel Griffith Anderson, Delai Chen, Yi Chen, Arturo Jose Vegas, Akinleye C. Alabi, Yunlong Zhang
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Patent number: 11460920Abstract: A hybrid wave computer that computes an inputted original signal as frequency information includes: an input module configured to separate a frequency of the original signal by detecting an oscillation of an piezoelectric element by each position as the original signal having an embedded frequency of several bands is transmitted in a form of acoustic waves on a substrate provided with the piezoelectric element; a calculation module including at least one vibration amplifier or vibration damper for receiving the frequency of the original signal separated in the input module and amplifying or attenuating a wave for each frequency band to calculate the inputted original signal in a frequency band; and a storage module configured to store binarized frequency information in the calculation module as digital information, so that the original signal is interfaced in a form of waves.Type: GrantFiled: December 8, 2017Date of Patent: October 4, 2022Assignee: Daegu Gyeongbuk Institute of Science and TechnologyInventors: Sang Cheol Lee, Woo Young Jung
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Patent number: 11461912Abstract: A method and system provide for temporal fusion of depth maps in an image space representation. A series of depth maps are obtained/acquired from one or more depth sensors at a first time. A first Gaussian mixture model (GMM) is initialized using one of the series of depth maps. A second depth map is obtained from the depth sensors at a second time. An estimate of the motion of the depth sensors, from the first time to the second time, is received. A predictive GMM at the second time is created based on a transform of the first GMM and the estimate of the motion. The predictive GMM is updated based on the second depth map.Type: GrantFiled: July 19, 2018Date of Patent: October 4, 2022Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGYInventors: Larry H. Matthies, Cevahir Cigla
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Publication number: 20220311963Abstract: The present invention belongs to the technical field of CMOS image sensors, and particularly relates to an on-chip multiplexing pixel control circuit for controlling a super-large area array splicing CMOS image sensor. The multiplexing type pixel control circuit includes at least one multiplexing unit, each multiplexing unit includes L levels of serial pixel control sub-circuits and a windowing address gating circuit. Through the different positions of the multiplexing units in the whole chip, the group address buffer circuits of the multiplexing units generate different group address reference signals, which are compared with a group decoding address generated in a group decoding address buffer circuit to realize group decoding and gate the multiplexing unit. Meanwhile, the serial pixel control sub-circuit in the multiplexing unit is compared with a row decoding address to realize exposure and readout control of a corresponding row of the multiplexing unit.Type: ApplicationFiled: April 22, 2020Publication date: September 29, 2022Applicant: CHINA ELECTRONICS TECHNOLOGY GROUP CORPORATION NO. 44 RESEARCH INSTITUTEInventors: Zhijun WU, Changju LIU, Yiqiang LI
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Publication number: 20220308036Abstract: The present disclosure discloses a method for assessing soil health of cultivated land, which adopts “three sets of dual index assessment systems”, that is an index system for current soil function and a healthy soil function required by crops, an index system for current soil nutrition and healthy soil nutrition required by crops, and an index system for current crop output of cultivated land and a crop output expected by cultivated land users or owners. The method solves the shortcomings of the existing assessment systems that the existing soil health assessment index system has no hierarchy and applicability. This method includes using deviating degree of ratio R e.g., the index current value C/index health value E of measured dual index from 1 as well as it is simple, and the assessment result may directly determine the indicators or factors that can be used for guiding soil improvement and conservation.Type: ApplicationFiled: November 18, 2021Publication date: September 29, 2022Applicant: Institute of Mountain Hazards and Environment, Chinese Academy of SciencesInventors: Gangcai Liu, Kai Hu, Xuan Wang
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Publication number: 20220309661Abstract: Disclosed is a method and apparatus for quantifying severity of infectious disease based on a vision transformer using a chest X-ray (CXR) image. Here, a method of quantifying severity of infectious disease based on a vision transformer includes receiving an input CXR image; extracting a feature map from the received input CXR image using a pretrained neural network; classifying a lesion in the input CXR image using the vision transformer based on the extracted feature map; and quantifying severity of the input CXR image based on the extracted feature map and the classified lesion.Type: ApplicationFiled: March 25, 2022Publication date: September 29, 2022Applicant: Korea Advanced Institute of Science and TechnologyInventors: JongChul Ye, Sangjoon Park, Gwanghyun Kim
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Publication number: 20220307003Abstract: The present disclosure provides novel adenine base editors that retain ability to edit DNA efficiently but show greatly reduced off-target effects, such as reduced RNA editing activity, as well as lower off-target DNA editing activity and reduced indel by product formation. Also provided are base editing methods comprising contacting a nucleic acid molecule with an adenine base editor and a guide RNA that has complementarity to a target sequence. Further provided are complexes comprising a guide RNA bound to a base editor provided herein; and kits and pharmaceutical compositions for the administration of adenine base editor variants to a host cell.Type: ApplicationFiled: April 16, 2020Publication date: September 29, 2022Applicants: The Broad Institute, Inc., President and Fellows of Harvard CollegeInventors: David R. Liu, Holly A. Rees
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Publication number: 20220311381Abstract: A measurement method of subcell photocurrents and a matching degree of the subcell photocurrents of a multi-junction photovoltaic cell is provided. The measurement method includes measuring an I-V characteristic of the multi-junction photovoltaic cell; and measuring currents corresponding to respective current steps in an I-V curve to obtain approximate values of short-circuit currents of subcells in the multi-junction photovoltaic cell, and then calculating a mismatching degree of the multi-junction photovoltaic cell using step currents. According to the measurement method, a current mismatching degree of the multi-junction photovoltaic cell is obtained by calculating the mismatching degree of the step currents occurring in the I-V curve. The measurement method is rapid and simple, the measurement method avoids complicated and time-consuming processes where the subcell photocurrents are calculated based on a standard light source spectrum integral with bias lights applied.Type: ApplicationFiled: May 28, 2021Publication date: September 29, 2022Applicant: SUZHOU INSTITUTE OF NANO-TECH AND NANO-BIONICS (SINANO) , CHINESE ACADEMY OF SCIENCESInventors: Ancheng WANG, Jianrong DONG, Yurun SUN, Shuzhen YU, Jiajing YIN
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Publication number: 20220306807Abstract: A polyimide, a film composition, and film prepared from the same are provided. The polyimide is a product of a reactant (a) and a reactant (b). The reactant (a) consists of a first dianhydride and a second dianhydride. The first dianhydride has a structure represented by Formula (I) and the second dianhydride has a structure represented by Formula (II) wherein R1, R2 and Ar1 are as defined in specification. The reactant (b) includes a first diamine, wherein the first diamine is and R3, R4, R5, or R6 are as defined in specification.Type: ApplicationFiled: December 29, 2021Publication date: September 29, 2022Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Yu-Yang SU, Yung-Lung TSENG, Chun-Wei SU
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Publication number: 20220309401Abstract: A method of improving performance of classification on the basis of mixed sampling is applied. The present invention is directed to providing a method and apparatus for improving the performance of classification on the basis of mixed sampling that are capable of, when learning a model that classifies types using deep learning by dividing the entire data set and using the divided data set for training, validation, and testing, applying different sampling techniques by types of data according to the characteristics of the training data in order to improve the classification performance.Type: ApplicationFiled: March 23, 2022Publication date: September 29, 2022Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventor: Won Joo PARK
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APPLICATIONS OF SERUM S100A8/A9 COMPLEX LEVEL IN PROGNOSIS ASSESSMENT OF ACUTE MYOCARDIAL INFARCTION
Publication number: 20220308067Abstract: Applications of a serum S100A8/A9 complex level in the prognosis assessment of acute myocardial infarction (AMI) are disclosed. The prognosis assessment refers to predicting short-term and long-term prognosis of an AMI patient undergoing percutaneous coronary intervention (PCI) and determining whether the patient falls into a high-risk group of postoperative adverse events (AEs) or a low-risk group of the postoperative AEs. The AEs include but are not limited to death, cardiogenic shock (CS), and acute heart failure (AHF). The S100A8/A9 complex is a heterodimer complex formed by S100A8 protein (Calgranulin A, MRP8) and S100A9 protein (Calgranulin B, MRP14) in a calcium ion-dependent manner. The S100A8/A9 complex refers to the S100A8/A9 complex in serum of the patient within 24 h after the PCI. An antibody pair for detecting the serum S100A8/A9 complex is also disclosed.Type: ApplicationFiled: August 16, 2019Publication date: September 29, 2022Applicant: BEIJING INSTITUTE OF HEART LUNG AND BLOOD VESSEL DISEASESInventors: Jie DU, Yulin LI, Xinying YANG, Ping LI -
Publication number: 20220306157Abstract: Disclosed are a vehicle-mounted camera gimbal servo system and a control method. The vehicle-mounted camera gimbal servo system includes a camera tri-axial gimbal and a servo control apparatus. The camera tri-axial gimbal includes a pitch motor, a roll motor, a yaw motor, a roll arm (1), a pitch arm (4), a yaw arm (5), a gimbal top (7), a camera (11), a pitch-axis bearing (12), and a counterweight block (13); the pitch motor includes a pitch motor stator (2) and a pitch motor rotor (3); the yaw motor includes a yaw motor stator (6) and a yaw motor rotor (8); the roll motor includes a roll motor stator (9) and a roll motor rotor (10); the servo control apparatus includes an inertial measurement unit, a three-dimensional modeling control unit, an angular velocity loop control unit, and an angular displacement loop control unit.Type: ApplicationFiled: July 13, 2020Publication date: September 29, 2022Applicant: Beijing Institute of TechnologyInventors: Chao Sun, Jianghao Leng
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Publication number: 20220310198Abstract: The present disclosure relates to antimicrobial compositions, particularly to antibiotic compositions; to methods for identification of antimicrobial compositions involving in silico prediction of antimicrobial activity; and to use of antimicrobial compositions and methods.Type: ApplicationFiled: September 9, 2020Publication date: September 29, 2022Applicants: MASSACHUSETTS INSTITUTE OF TECHOLOGY, THE BROAD INSTITUTE, INC.Inventors: James Collins, Regina Barzilay, Jonathan Stokes, Ian Andrews, Daniel Collins
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Publication number: 20220311996Abstract: Disclosed herein are a method and apparatus for image encoding and decoding using prediction based on a block shape. Whether a prediction mode is available for a target block is determined. The determination is performed based on the shape of the target block. When the prediction mode is determined to be unavailable for the target block, signaling related to the prediction mode may be omitted, and determination of an additional prediction mode is performed. When the prediction mode is determined to be available for the target block, information indicating whether the prediction mode is to be used for the target block is signaled.Type: ApplicationFiled: June 22, 2020Publication date: September 29, 2022Applicants: Electronics and Telecommunications Research Institute, UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITYInventors: Gun BANG, Gwang-Hoon PARK, Woong LIM, Hui-Yong KIM, Woo-Woen GWUN, Tae-Hyun KIM, Dae-Young LEE, Won-Jun LEE
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Publication number: 20220306597Abstract: Embodiments of the present invention provide for syntheses and uses of mechanism-based nutritional colorants from vitamin C and amino-containing compounds, wherein the amino-containing compounds can be one of natural compounds or synthetic compounds, wherein the amino-containing compounds can be made through environmentally-friendly radical reactions that follow the antioxidant mechanism of action of vitamin C.Type: ApplicationFiled: March 25, 2021Publication date: September 29, 2022Applicant: WALKER CANCER RESEARCH INSTITUTE, INC.Inventor: Eduardo Palomino
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Publication number: 20220306338Abstract: Proposed is an anti-vibration pallet. More particularly, the present disclosure relates to an anti-vibration pallet that is capable of realizing an effect of an air spring by using only a combination of an auxiliary mount and a main mount that are formed of elastic bodies provided between an upper plate and a lower plate, and is also capable of maximizing an anti-vibration performance by controlling an optimal anti-vibration load according to a cargo load. In order to achieve the objectives described above, the present disclosure includes: an upper plate on which cargo is loaded on a top portion thereof; a lower plate positioned below the upper plate; a main mount installed between the lower plate and the upper plate; and an auxiliary mount installed outside the main mount.Type: ApplicationFiled: May 3, 2021Publication date: September 29, 2022Applicant: KOREA RAILROAD RESEARCH INSTITUTEInventor: Seung-Ho JANG
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Publication number: 20220305215Abstract: A kit for resuscitating a subject, particularly a neonatal patient, is described. In an embodiment, the kit includes a syringe having a tip defining a male Luer taper fitting, and an adaptor defining a first end portion shaped to couple with the male Luer taper fitting and a second end portion shaped to cooperatively couple with an opening of an endotracheal tube.Type: ApplicationFiled: March 25, 2022Publication date: September 29, 2022Applicant: Seattle Children's Hospital d/b/a Seattle Children's Research InstituteInventors: Heather Anne Cruz, Jennifer Janett Cerdena
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Publication number: 20220306484Abstract: Single crystals of a new noncentrosymmetric polar oxysulfide SrZn2S2O (s.g. Pmn21) grown in a eutectic KF-KCl flux with unusual wurtzite-like slabs consisting of close-packed corrugated double layers of ZnS3O tetrahedra vertically separated from each other by Sr atoms and methods of making same.Type: ApplicationFiled: June 10, 2022Publication date: September 29, 2022Applicants: University of South Carolina, National Institute For Materials ScienceInventors: Hans-Conrad Zur Loye, Yoshihiro Tsujimoto
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Publication number: 20220306496Abstract: Direct contact membrane distillation (DCMD) was used to generate high purity water from bacteria and endotoxin-contaminated water. The DCMD system includes a nanocarbon-coated membrane. Exemplary nanocarbon-coated membranes include a layer of carbon nanotubes immobilized relative to a polytetrafluorethylene surface (CNIM), a layer of carboxylate functionalized carbon nanotubes immobilized in the PTFE (CNIM-COOH), and a layer of graphene oxide immobilized in the PTFE (GOIM). The nanocarbon-immobilized membranes are effective in generating ultrapure, medical grade water.Type: ApplicationFiled: March 22, 2022Publication date: September 29, 2022Applicant: New Jersey Institute of TechnologyInventors: Somenath Mitra, Indrani Gupta, Joydeep Chakraborty