Abstract: A transistor includes a substrate; a pair of constant current forming regions provided in the substrate; a pair of source/drain regions respectively provided on the pair of constant current forming regions in the substrate; and a gate structure provided between the pair of source/drain regions, wherein any one of the constant current forming regions immediately adjacent to any one of the pair of source/drain regions serving as a drain forms a constant current between the any one of the pair of source/drain region serving as the drain and the any one of the constant current forming regions.

Abstract: The adsorptive power and load capacity of an electrostatic chuck is vastly improved by maintaining an optimal state for in-plane stress produced at the interface between an adsorption surface and an object. The electrostatic adsorption module of the invention comprises a tip member having a bipolar adsorption surface and a support member that supports the tip member, wherein the tip member as a whole can be elastically displaced in the near and far direction with respect to the object to be adsorbed, and the tip member and the support member are coupled via a freely rotatable joint. The electrostatic adsorption device is provided with multiple tip members with bipolar adsorption surfaces that can be elastically displaced in the near and far direction with respect to the object to be adsorbed, the support member supporting the tip members extending from a substrate and the substrate being deformable.

Abstract: The present invention provides a pH-responsive lipid derivative represented by a structure represented by the following formula (i): (in the above-mentioned formula, each symbol is as described in the specification), and a pH-responsive transport carrier which is useful as a transport carrier for safely and efficiently performing delivery of low-molecular-weight drugs and the like to tumor tissues.

Abstract: A polymer, a thickening agent, and a preparation method therefor are provided. The polymer contains structural units of formula (1), formula (2), of formula (3), and of formula (4). The thickening agent contains the polymer and has instant solubility. It can be used for thickening slickwater, a glue solution, a cross-linked fracturing fluid and an acid solution having different viscosities, which improves compatibility between different fracturing fluids. Various fracturing fluid systems prepared by using the thickening agent have good temperature resistance, shearing resistance, sand-carrying performance, and a slow speed.

Abstract: The invention concerns a modified recombinant foot and mouth disease virus (FMDV) VP2 protein and further concerns an FMDV capsid precursor protein P1 comprising the modified VP2 protein. In a specific aspect, the present invention concerns a VP2 protein or a capsid precursor protein P1 comprising the VP2 protein, wherein the amino acid sequence of the VP2 protein is modified to improve the stability of FMDV capsids. The invention further relates to an isolated nucleic acid molecule and an expression vector comprising the nucleic acid molecule for recombinant expression of the modified VP2 protein or a capsid precursor protein P1 comprising the VP2 protein. In further aspects, the invention relates to a virus-like particle (VLP) obtained from the modified capsid precursor protein P1 and a vaccine for use in the protection of a subject against an infection with FMDV produced from the VLP.

Abstract: A method for a breast biopsy based on indirect magnetic resonance imaging (MRI) guidance of present disclosure, may comprises obtaining a breast MRI data of a patient, generating a deformable breast model using the breast MRI data, measuring real-time breast shape of the patient using a depth sensor, performing a real-time deformable registration using the deformable breast model and the real-time shape data, estimating movements of the MRI targets inside of the breast, performing a breast biopsy for the MRI targets.

Abstract: Described are the bifunctional compounds, compositions and methods of treating a disease or disorder characterized by aberrant extracellular-signal-regulated kinase 5 (ERK5) activity.

Abstract: An assembly includes a frame configured to couple to a valve, an actuating arm movably coupled to the frame and configured to move a movable component of the valve to adjust a position of the movable component, and a biasing member coupled to the actuating arm and the frame. The biasing member is configured to bias the actuating arm in a first direction relative to the frame. The assembly further includes one or more shape memory alloy (SMA) elements coupled to the actuating arm and the frame. Responsive to an activation that causes the one or more SMA elements undergo a dimensional transformation, the one or more SMA elements are configured to operate against the biasing member to bias the actuating arm in a second direction opposite the first direction relative to the frame.

Abstract: A method for evaluating Dry Eye Disease (“DED”) in a human or animal subject is provided. Thread thinning dynamics of a tear sample of the subject are determined using an acoustically-driven microfluidic extensional rheometry instrument. At least one physical parameter value of the tear sample is calculated based at least in part on the determined thread thinning dynamics. DED is evaluated based at least in part on the at least one calculated physical parameter value of the tear sample. A device for evaluating Dry Eye Disease (DED) in a human or animal subject is also provided. The device includes an acoustically-driven microfluidic extensional rheometry instrument and a processing device configured to evaluate DED based at least in part on the calculated at least one physical parameter value of the tear sample.

Abstract: A method for manufacturing a hydrocarbon compound from carbon dioxide, said method including: (a) a step of preparing an absorption-conversion catalyst that includes an oxide carrier, a first component supported on the oxide carrier and including at least one type of metal selected from the group consisting of alkali metals and alkaline earth metals, and a second component supported on the oxide carrier and including at least one type of metal selected from the group consisting of Ni, Fe, Co, Cu, and Ru; (b) a step of bringing the absorption-conversion catalyst and a carbon dioxide-including gas into contact under higher pressure than atmospheric pressure, and causing the carbon dioxide to be stored in the absorption-conversion catalyst; and (c) a step of bringing the absorption-conversion catalyst that has the carbon dioxide stored therein and a reducing gas into contact under higher pressure than atmospheric pressure, and obtaining the hydrocarbon compound.

Abstract: The application relates to a dextran affinity tag and use thereof. The present application provides an affinity tag, which is a segment of dextran binding domain, and can purify a target protein by its affinity with the dextran. The affinity tag of the present application has the advantages of more efficient in preparation and purification, and can be widely used in industrial applications that require protein purification processes.

Abstract: The coastal ecosystem carbon pool estimation method of the invention belongs to the field of environmental assessment, and includes the following steps: (a) determining the spatial boundary of the coastal ecosystem; (b) determining the dominant plant classification area of the coastal ecosystem; (c) calculating the carbon source of the freshwater plant dominant area; (d) size setting of carbon source sampling point in coastal ecosystem; (e) sampling method of carbon source sampling point in coastal ecosystem; (f) carbon source estimation method in coastal ecosystem.

Abstract: Provided is a wireless communication terminal that communicates wirelessly. The terminal includes: a transceiver; and a processor. The processor is configured to receive a frame through the transceiver, determine whether the frame is classified into an Intra-Basic Service Set (BSS) frame or an Inter-BSS frame according to a BSS from which the frame is transmitted, and access a channel according to whether the frame is an Intra-BSS frame or an Inter-BSS frame.

Abstract: Provided is a CRY2 variant in which E279 and/or E281 having a negative charge in a N277SEGE281 sequence of SEQ ID NO: 1 is substituted with any one selected from the neutral amino acid group of alanine (A), isoleucine (I), leucine (L), valine (V), phenylalanine (F), methionine (M) and tryptophan (W), or in which S278 or G280 of a N277SEGE281 sequence of SEQ ID NO: 1 is substituted with any one selected from the bulky amino acid group of tryptophan (W) and phenylalanine (F).

Abstract: Disclosed is a gait start intention detection device for detecting a walker's gait start intention, including a plurality of left foot sole sensor units and a plurality of right foot sole sensor units to measure ground reaction force signals generated from foot soles while walking, and a calculation unit to receive and calculate the left ground reaction force signal and the right ground reaction force signal, wherein the calculation unit calculates a center of pressure (COP) location in a walking direction and a direction perpendicular to the walking direction using data of the ground reaction force signal measured from each sensor unit, and detects the walkers gait start intention when a ground reaction force of a swing foot heel of the walker increases, and at the same time, the COP location moves to a rear side of the walker.

Abstract: The catalytic cracking catalyst contains a molecular sieve and an alumina substrate material. The alumina substrate material has a crystalline phase structure of ?-alumina. Based on the volume of pores with a diameter of 2-100 nm, the pore volume of the pores with a diameter of 2-5 nm accounts for 0-10%, the pore volume of the pores with a diameter of more than 5 nm and not more than 10 nm accounts for 10-25%, and the pore volume of the pores with a diameter of more than 10 nm and not more than 100 nm accounts for 65-90%.

Abstract: The present disclosure provides a method and a device for decentralized edge computing. An edge device for implementing decentralized edge computing using a plurality of neural networks having a stacked architecture is provided, including an uncooperative unit configured to generate an initial decision using a neural network of zero-th layer that is a lowest layer of the stacked architecture, an adjacently cooperative unit configured to generate a first transmission messages and a first decision using a pair of neural networks of a first layer, and a network-wide cooperative unit configured to generate a second transmission messages and a second decision using a pair of neural networks of a second layer.

Abstract: A system (100) for sheet metalworking comprising a punch (1) connectable to a press (P), wherein the punch (1) is configured with a first electrical terminal (2). A die (3) configured with a die surface (DS), to support sheet metal (SM). A support member (4) movably disposed in the die (1), the support member (4) is provided with a second electrical terminal (5). The support member (4) and the punch (1) contacts a working portion (B) of the sheet metal (SM) at an axis (A-A) to supply electric current to a localized region (LR) of the working portion (B) for sheet metalworking.

Abstract: A continuously-variable transmission (CVT) has: a gearbox having a first planetary gear train, a second planetary gear train, a first rotating spool defined by one of two sun gears, two ring gears, and two carriers of the first and second planetary gear train, a second rotating spool defined by another one of the two sun gears, the two ring gears, and the two carriers, an input defined by a remaining one of the first sun gear, the first carrier, and the first ring gear, and an output defined by a remaining one of the second sun gear, the second carrier, and the second ring gear; a first brake operatively connected to the first rotating spool; a second brake operatively connected to the second rotating spool; and a transmission motor drivingly engaged to the first rotating spool or to the second rotating spool.

Abstract: The present disclosure relates to a surface-enhanced Raman spectroscopy complex probe capable of effectively detecting a catecholamine compound even at extremely low concentrations. The complex probe includes a nanolaminate including a nanogap and metal nanoparticles. In this case, the nanolaminate and the metal nanoparticles are modified to a compound that may be bound to each functional group included in catecholamine, and thus, catecholamine included in an analyte is doubly recognized by the complex probe. In addition, since a hotspot emitting a strong SERS signal is formed by a nanogap included in a nanolaminate, it is possible to effectively detect a catecholamine compound even at extremely low concentrations.