Abstract: This application relates generally to the production of modified, non-natural ?1-?2 domains of NKG2D ligands with attached polypeptides having specific target-binding properties, for example, antibodies or variable fragments of antibodies, that are selectively delivered to Chimeric Antigen Receptors (CARs) comprised of modified, non-natural NKG2D receptors on engineered mammalian cells. The targeting of surface-expressed molecules includes those of virus-infected cells that can then be attacked and ablated by engineered cells of the immunity system expressing CARs cognate to the modified, non-natural ?1-?2 domains of NKG2D ligands with attached polypeptides.

Abstract: A glenoid implant for an inverted shoulder prosthesis includes a base, a glenosphere having a central orifice and mounted on the base by mutual wedging between conical bearing surfaces, a main anchoring screw crossing the base and including an anchor rod having a tapped end segment, and an inner hole having a threaded intermediate portion, and a tip portion. A locking screw crosses the central orifice and includes a proximal head and a locking rod having an end segment intended to slide in the tip portion of the inner hole and a tapped intermediate segment intended to cooperate by screwing with the intermediate portion of the inner hole to lock the mutual wedging of the conical bearing surfaces, the proximal head abutting on an annular bearing surface in the central orifice.

Abstract: A method for producing a thin-film solar module with serially connected solar cells and related device. A back electrode layer is deposited on one side of a flat substrate and subdivided by first patterning trenches. An absorber layer is deposited over the back electrode layer and subdivided by second patterning trenches. A front electrode layer is deposited over the absorber layer. At least the front electrode layer is subdivided by third patterning trenches. A direct succession of a first patterning trench, a second patterning trench, and two adjacent third patterning trenches forms a patterning zone. The third patterning trenches are produced by laser ablation through a pulsed laser beam, where one third patterning trench is produced with laser pulses of higher energy and the other third patterning trench of the patterning zone is produced with laser pulses of lower energy.

Abstract: Methods and kits for sequencing and quantification of small RNA molecules from small quantities of starting materials, including single cells, are disclosed. The invention can be applied to, among others, preparing small RNA libraries, synthesizing cDNA from small RNAs, characterizing small RNAs from various cell types, studying cellular heterogeneity in pathological conditions, and diagnosing diseases.

Abstract: A robotic tool changer is provided including a tool adapter. The tool adapter includes a body having a robot wall, a tool wall, and a side wall extending from the robot wall to the tool wall. A rear opening is formed in the side wall and the tool wall through which a tool element extends to enter a tool hole formed in the body. The tool adapter also includes a locking member movable relative to the body between an open position in which the locking member permits positioning of the tool element into or out of the tool hole through the rear opening, and a closed position in which the locking member prohibits positioning of the tool element into or out of the tool hole through the rear opening.

Abstract: An apparatus for inhibiting formation of calcium based crystal, in which formation of calcium based crystals is inhibited by adding an optimal amount of magnesium to raw water having a high concentration of calcium ions and a high variation in calcium ion concentration and an apparatus for water treatment using the same.

Abstract: Provided is a novel analysis method which, when a chemical sensor is used to perform a measurement, makes it possible to identify a sample without controlling or monitoring a change in the time the sample is introduced. According to the present invention, a sample can be identified without knowing a change in the time the sample is introduced, by using a chemical sensor having a plurality of channels each having different characteristics to perform a measurement, and performing an analysis on the basis of responses obtained from each channel.

Abstract: Embodiments of the present invention provide a technique for forming a film having a high added value appearance quality and excellent hardness on the surface of a steel sheet in a short time.

Abstract: A fingerprint recognition method is provided. The method includes obtaining a plurality of fingerprint images by sensing a finger of a user, respectively calculating geometric center points corresponding to the fingerprint images, and calculating positions and offsets of the fingerprint images according to the geometric center points. The method also includes filling signals in the fingerprint images into a part of pixels in a pixel array according to the positions and the offsets of the fingerprint images, and obtaining signals of other pixels in the pixel array by inputting the signals filled in the part of pixels in the pixel array into an artificial intelligence engine. The method further includes generating a candidate fingerprint image and recognizing a user based on the candidate fingerprint image.

Abstract: The present invention relates to a pharmaceutical composition and a health functional food composition, which include phloroglucinol active ingredient, for preventing, treating, or ameliorating somnipathy and suppressing intolerance to, alleviating, or ameliorating side effects of an agonist at the benzodiazepine binding site of the GABA-A receptor. The pharmaceutical composition and the food composition rapidly and reliably induce and maintain sleep, prevent repeated awakenings, unalter physiological sleep architecture, are particularly devoid of residual sedative effects, which could impair daytime functioning and cognitive performance, and neither cause side effects nor intolerance to a conventional agonist at the benzodiazepine binding site of the GABA-A receptor despite long-term administration.

Abstract: A method, apparatus and system required to realize an optimization opportunity are disclosed. If an expression involves unsequenced evaluations involving side-effects and optionally references, then the expression is translated into optimized code that may involve optimized register usage, or optimized use of the underlying vectorization hardware. An alias-analysis logic is able to identify must-not-alias relationships through such expression tree structures. These must-not-alias relationships are helpful not just in optimizing the performance of that particular expression (from which these must-not-alias relationships were derived) but also in the performance of any other surrounding program statements that access the state elements participating in these must-not-alias relationships.

Abstract: Provided are a method and apparatus for localizing a multichannel sound signal. The method includes: obtaining a multichannel sound signal to which sense of elevation is applied by applying a first filter to an input sound signal; determining at least one frequency range of a dynamic cue according to change of a head-related transfer function (HRTF) indicating information regarding paths from a spatial location of an actual speaker to ears of an audience; and applying a second filter to at least one sound signal, corresponding to the determined at least one frequency range, of at least one channel in the multichannel sound signal to change the at least one sound signal so as to remove or to reduce the dynamic cue when the multichannel sound signal is output.

Abstract: A pixel structure includes an original light emitting diode die and a repairing light emitting diode die emitting light of a same color, and an extending conductor. The original light emitting diode die includes a first epitaxial layer, and a first electrode and a second electrode disposed at opposite sides of the first epitaxial layer. The repairing light emitting diode die includes a second epitaxial layer, and a third electrode and a fourth electrode disposed at a same side of the second epitaxial layer. The extending conductor includes a first portion, a second portion and a cut-off region. The first portion is electrically connected to the second electrode of the original light emitting diode die. The second portion is electrically connected to the third electrode of the repairing light emitting diode die. The cut-off region is located in the first portion or between the first portion and the second portion.

Abstract: The present invention discloses a hypocrellin derivative substituted both in a pen-position and in a 2-position by an amino, and a preparation method and use thereof. A general structural formula of the derivative is as represented by formulas I-a to I-d: The hypocrellin derivative substituted both in a peri-position and in a 2-position by an amino prepared in the present invention has a maximum absorption wavelength of 600-650 nm and a molar extinction coefficient reaching about 20000-40000 M?1cm?1. Compared with unmodified hypocrellin or hypocrellin having only a 2-position modified, an absorption spectrum of the derivative is significantly red-shifted and the molar extinction coefficient is greatly improved, and the derivative can efficiently produce reactive oxygen species such as singlet oxygen in a photosensitive condition.

Abstract: The present disclosure is directed toward optical elements, such as sample cuvettes, lenses, prisms, and the like, whose transmissivity is increased by the addition of a geometric anti-reflection layer disposed on at least one surface of the optical element, where the geometric anti-reflection layer includes a plurality of geometric features that collectively reduce the reflectivity of the interface between the surface and another medium. As a result, more of an optical signal incident on the surface passes through the interface. In some embodiments, every surface through which an optical signal passes includes a geometric anti-reflection layer. Due to the increased transmissivity of the optical element, in some embodiments, the use of low-cost, high-refractive-index materials, such as conventional silicon, is enabled.

Abstract: The invention relates to control compositions for a quantitative polymerase chain reaction. More particularly, the invention relates to control compositions for a quantitative polymerase chain reaction having at least one barcode sequence fragment and at least a first and a second primer binding site fragment, and to methods of their use.

Abstract: A method of making a silicon on insulator structure comprises: providing a bonded structure, the bonded structure comprises the first substrate, the second substrate and the insulating buried layer, the insulating buried layer is positioned between the first substrate and the second substrate; peeling off a layer of removing region of the first substrate from the bonded structure to obtain a first film; at a first temperature, performing a first etching to etch the first film to remove a first thickness of the first film; at a second temperature, performing a second etching to etch the first film to planarize the first film and remove a second thickness of the first film, the first temperature being lower than the second temperature, the first thickness being greater than the second thickness, and a sum of the first thickness and the second thickness being a total etching thickness of the first film.

Abstract: A forced separation device includes a transmission shaft, a main shaft, an electromagnetic transmission mechanism, a blasting separation mechanism and a pressure-resistant cabin. A pressing cover is fastened to the upper portion of the pressure-resistant cabin. The electromagnetic transmission mechanism is provided with a driving chuck and a driven chuck. The driving chuck is connected with the transmission shaft, the driven chuck is connected with the main shaft, the pressing cover is welded with the transmission shaft, and the driven chuck is welded with the lower portion of the pressure-resistant cabin. The blasting separation mechanism is provided with explosive packages and detonators. A plurality of explosive packages are distributed between the pressing cover and the top surface of the pressure-resistant cabin, and each explosive package is connected with the corresponding detonator respectively. The pressure-resistant cabin is further internally provided with a storage battery.

Abstract: An image encoding/decoding method is disclosed. An image decoding method of the present invention may comprise deriving an intra-prediction mode of a current block by using an intra-prediction mode of a neighbor block adjacent to the current block, configuring a reference sample of the current block, and performing intra-prediction on the current block by using the intra-prediction mode and the reference sample, wherein when the intra-prediction mode of the neighbor block is unavailable, the intra-prediction mode of the neighbor block may be replaced with a planar mode.

Abstract: A computing device learns a directed acyclic graph (DAG). An SSCP matrix is computed from variable values defined for observation vectors. A topological order vector is initialized that defines a topological order for the variables. A loss value is computed using the topological order vector and the SSCP matrix. (A) A neighbor determination method is selected. (B) A next topological order vector is determined relative to the initialized topological order vector using the neighbor determination method. (C) A loss value is computed using the next topological order vector and the SSCP matrix. (D) (B) and (C) are repeated until each topological order vector is determined in (B) based on the neighbor determination method. A best topological vector is determined from each next topological order vector based on having a minimum value for the computed loss value. An adjacency matrix is computed using the best topological vector and the SSCP matrix.