Abstract: Disclosed herein are polymers containing repeating units of formula (I) or copolymers containing the repeating units of formula (I) and (II), where R1 to R12, m, n, p, q, x and y are as defined herein. The polymers and copolymers have an antimicrobial effect and may be used therapeutically or in formulations intended for use as detergents.
Type:
Grant
Filed:
April 18, 2018
Date of Patent:
September 13, 2022
Assignees:
Nanyang Technological University, Massachusetts Institute of Technology
Inventors:
Bee Eng Mary Chan, Paula T. Hammond, Bo Liu, Wenbin Zhong
Abstract: A method for joint measuring argon-argon age and cosmic ray exposure age of an extraterrestrial sample is provided. The method for joint measuring determining argon age and cosmic ray exposure age may include: step A, sample packaging; step B, placing the packaged samples into a neutron reactor for irradiation; and step C, determining Ar isotopes of the packaged samples after being performed with a neutron irradiation and thereby calculating argon-argon age and cosmic ray exposure age. The method can overcome the defects of the prior art, and achieve high-precision simultaneous determination of the argon-argon age and the cosmic ray exposure age of samples.
Type:
Grant
Filed:
December 10, 2021
Date of Patent:
September 13, 2022
Assignee:
INSTITUTE OF GEOLOGY AND GEOPHYSICS
Inventors:
Fei Su, Huaiyu He, Ziheng Liu, Jiannan Li, Ruihong Yang
Abstract: Described are novel nicotine-binding antibodies and methods of using them for treating nicotine addiction and/or facilitating smoking cessation, or for treating nicotine overdose or nicotine poisoning.
Type:
Grant
Filed:
August 14, 2018
Date of Patent:
September 13, 2022
Assignees:
ANTIDOTE THERAPEUTICS, INC., BliNK BIOMEDICAL, Hennepin Healthcare Research Institute
Inventors:
Matthew W. Kalnik, Thomas Thisted, Nicola Beltraminelli, Stéphanie Fallot, Zuzana Biesova, Steve Fuller, Mark G. Lesage, Paul Pentel
Abstract: The present invention provides a planar three-dimensional displacement sensor for a multiaxis machining device. With the measurement of the (planar) three-dimensional displacement sensor in the multiaxis machining device, the multiaxis machining device and a multiaxis machining compensation method are able to eliminate various deformation effects effectively.
Type:
Grant
Filed:
December 25, 2019
Date of Patent:
September 13, 2022
Assignee:
National Chung-Shan Institute of Science and Technology
Abstract: Embodiments relate to a method including obtaining m measured values for each field sensor by measuring with respect to a first sensor group including first type of field sensors and a second sensor group including different second type of field sensors, which are attached to the rigid body, at m time steps; and calibrating a sensor frame of the first type of field sensor and a sensor frame of the second type of field sensor by using a correlation between the first type of field sensor and the second type of field sensor based on measured values of at least some of the m time steps, wherein the multiple field sensors include different field sensors of a magnetic field sensor, an acceleration sensor, and a force sensor, and a system therefor.
Type:
Grant
Filed:
November 24, 2020
Date of Patent:
September 13, 2022
Assignee:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Ig Jae Kim, Je Hyeong Hong, Donghoon Kang
Abstract: This disclosure provides a scalable and reproducible process to create complex 3D metal materials with sub-micron features by applying lithographic methods to transparent metal- or inorganic-rich polymer resins.
Type:
Grant
Filed:
October 30, 2019
Date of Patent:
September 13, 2022
Assignee:
California Institute of Technology
Inventors:
Andrey Vyatskikh, Stephane J. Delalande, Julia R. Greer
Abstract: Disclosed is a resonator for expanding a transfer distance. A conical resonator includes a metal layer configured to operate according to a resonant frequency, and a dielectric layer coupled to the top or bottom of the metal layer to space the metal layer apart from another metal layer without overlap, wherein the metal layer and the dielectric layer have a Swiss-roll structure, and include an input face to which power is supplied on the bottom and an open face on the top.
Type:
Grant
Filed:
November 27, 2020
Date of Patent:
September 13, 2022
Assignee:
ELECTRONICSAND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Jung Ick Moon, Je Hoon Yun, In Kui Cho, Ho Jin Lee, Sang-Won Kim, Seong-Min Kim, Jang Yeol Kim, Jaewoo Lee, Hyunjoon Lee, Dong Won Jang
Abstract: The present invention relates to a floating hydrophyte planting device, comprising a height-adjustable support, a buoyant rope, a planting net rope, a stabilizing rope and hydrophytes. The height-adjustable support comprises a fixed part and a movable part. The fixed part comprises columns and inclined stayed and fixed steel wires. A sawtooth groove is arranged on one side face of the column in the height direction and has multiple notches at different heights. The movable part comprises a twisting pull rod. The twisting pull rod is provided with a cross locking column vertical to the body of the twisting pull rod. The locking column is limited in the notch. After the twisting pull rod is twisted, the cross locking column may separate from the notch; after the twisting pull rod moves in the vertical direction and is twisted again, the cross locking column is limited in another notch.
Type:
Grant
Filed:
May 27, 2020
Date of Patent:
September 13, 2022
Assignee:
FISHERY MACHINERY AND INSTRUMENT RESEARCH INSTITUTE, CHINESE ACADEMY OF FISHERY SCIENCES
Abstract: Thioesters, thiocarbamates, thiocarbazates, semithiocarbazates, peptides, aza-amino acid conjugates, and azapeptides; and a chemoselective and site-specific functionalization protocol of protected thiocarbazates and semithiocarbazates are described. The protocol features the use of Mitsunobu reaction to alkylate specifically the nitrogen atom close to the acylthiol moiety with alcohols to produce protected mono-substituted thiocarbazates that can be stored for months, activated under mild conditions at low temperature using halonium reagents and integrated orthogonally to make substituted semicarbazides that can be used, e.g., as synthons in synthesis of aza-amino acid conjugates, azapeptides and other peptidomimetics.
Type:
Grant
Filed:
May 8, 2020
Date of Patent:
September 13, 2022
Assignee:
THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
Abstract: Disclosed is a hydrofining catalyst comprising: an inorganic refractory component comprising a first hydrodesulfurization catalytically active component in a mixture with at least one oxide selected from the group consisting of alumina, silica, magnesia, calcium oxide, zirconia and titania; a second hydrodesulfurization catalytically active component; and an organic component comprising a carboxylic acid and optionally an alcohol. The hydrofining catalyst of the present application shows improved performance in the hydrofining of distillate oils. Also disclosed are a hydrofining catalyst system comprising the hydrofining catalyst, a method for preparing the catalyst and catalyst system, and a process for the hydrofining of distillate oils using the catalyst or catalyst system.
Type:
Grant
Filed:
April 9, 2019
Date of Patent:
September 13, 2022
Assignees:
CHINA PETROLEUM & CHEMICAL CORPORATION, RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPEC
Inventors:
Wenbin Chen, Le Zhang, Xiangyun Long, Hong Nie, Mingfeng Li, Dadong Li, Qinghe Liu, Xueyan Ju
Abstract: The present disclosure relates to method of distinguishing between two or more species of one or more organisms in a sample, by contacting a biological sample comprising ribosomal ribonucleic acid (rRNA) with a set of antisense probes, wherein the set of probes contains at least one detectable probe that is specific for a target rRNA sequence of each species to be tested, and wherein the individual probes specific for each species comprises less than about 85% sequence identity; and, detecting hybridization between one or more of the probes and the rRNA, thereby distinguishing between two or more species in a sample.
Type:
Grant
Filed:
March 14, 2014
Date of Patent:
September 13, 2022
Assignees:
THE BROAD INSTITUTE, INC., THE GENERAL HOSPITAL CORPORATION
Inventors:
Roby Bhattacharyya, Deborah Hung, Jonathan Livny
Abstract: Disclosed is a self-powered real-time monitoring system for fluid flushing of an underwater fixed foundation. Said system converts wave energy into electrical energy by means of a wind energy capturing module and a wave energy capturing module, and then uses the electrical energy to supply power to a settlement monitoring module, achieving the reduction of power consumption of the settling monitoring module during the detection of underwater surface settlement at the periphery of a fixed foundation.
Abstract: A method of growing semiconductor layers may include: growing a first semiconductor layer on a surface of a substrate at which a crystal layer is exposed, wherein the first semiconductor layer is different from the crystal layer in at least one of a material and a crystal structure; cutting the first semiconductor layer such that a cut surface of the first semiconductor layer extends from a front surface of the first semiconductor layer to a rear surface of the first semiconductor layer; and growing a second semiconductor layer on the cut surface of the first semiconductor layer, wherein the second semiconductor layer has a material and a crystal structure that are same as those of the first semiconductor layer.
Type:
Grant
Filed:
April 27, 2020
Date of Patent:
September 13, 2022
Assignees:
DENSO CORPORATION, NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY
Abstract: A controller performs a first process of scanning a cylindrical irradiation region including a focused spot of laser light emitted from a laser light emitter to machine a flank face side of a workpiece to manufacture a cutting tool having a plurality of cutting edges arranged in line. In the first process, the controller scans the cylindrical irradiation region along a scanning path that has periodicity and changes a machining depth to form the plurality of cutting edges. The controller further performs a second process of scanning the cylindrical irradiation region including the focused spot of the laser light emitted in a direction different from an irradiation direction of the laser light in the first process to machine a rake face side of the workpiece.
Type:
Grant
Filed:
February 25, 2020
Date of Patent:
September 13, 2022
Assignees:
National University Corporation Tokai National Higher Education and Research System, Nagoya Institute of Technology
Abstract: A generic point of care based portable device and method thereof as a platform technology for detecting pathogenic infection via nucleic acid based testing achieving sample-to-result integration, comprising the following interconnected stand-alone modules: a thermal unit for executing piece-wise isothermal reactions in a pre-programmable concomitant fashion without necessitating in-between operative intervention; a colorimetric detection unit seamlessly interfaced with smartphone-app based analytics for detecting the target analyte.
Type:
Grant
Filed:
March 15, 2021
Date of Patent:
September 13, 2022
Assignee:
INDIAN INSTITUTE OF TECHNOLOGY KHARAGPUR
Abstract: The present invention relates to a vaginal sustained-release drug delivery system for luteal support and a method for preparation and use thereof. The vaginal sustained-release drug delivery system for luteal support is a progesterone depot-type vaginal ring having a bilayer structure of a core layer and a film layer enclosing the core layer, wherein the core layer is composed of a solid scaffold carrier of medical EVA containing a drug uniformly dispersed therein, and the film layer is composed of a medical EVA material containing no drug. The vaginal sustained-release drug delivery system for luteal support according to the present invention can be used for assisted reproduction and for treatment of functional uterine bleeding, premenstrual syndrome and the like due to luteal phase defect with a significantly improved therapeutic effect.
Type:
Grant
Filed:
October 12, 2019
Date of Patent:
September 13, 2022
Assignee:
NATIONAL RESEARCH INSTITUTE FOR FAMILY PLANNING
Inventors:
Meiying Ning, Liangyu Xia, Xu Ma, Bin He
Abstract: A device for generation of genuine random numbers, uses quantum stochastic processes in optical parametric nonlinear media. The dimensionality of the random numbers is varied from 2 to over 100,000. Their statistical properties, including the correlation function amongst random numbers, are tailored using linear and nonlinear optical circuits following the parametric nonlinear media. Both the generation and manipulation of random numbers are integrated on a single nanophotonics chip. By incorporating optoelectric effects, fast streams of random numbers are created in custom statistical properties, which are updated or reconfigured in real time, such as at 10 GHz speed. The unpredictability of the random numbers is quantifying by evaluating their min-entropy. The genuineness of quantum random numbers is tested using both statistical tools and independently verified by measuring the quantum entanglement between the photons in real time.
Type:
Grant
Filed:
June 27, 2018
Date of Patent:
September 13, 2022
Assignee:
THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY
Abstract: A neural probe structure includes a probe that is inserted into a subject, a body to support a rear end of the probe, at least one light source included in the body, a photo diode formed in the probe, and an optical waveguide extending from the at least one light source in the body to the photo diode of the probe, wherein the photo diode is formed at a smaller height than the optical waveguide.
Type:
Grant
Filed:
June 8, 2020
Date of Patent:
September 13, 2022
Assignee:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Abstract: Disclosed is a method of producing an olefin using a circulating fluidized bed process, including: (a) supplying a hydrocarbon mixture including propane and a dehydrogenation catalyst to a riser which is in a state of a fast fluidization regime, and thus inducing a dehydrogenation reaction; (b) separating an effluent from the dehydrogenation reaction into the catalyst and a propylene mixture; (c) stripping, in which a residual hydrocarbon compound is removed from the catalyst separated in step (b); (d) mixing the catalyst stripped in step (c) with a gas containing oxygen and thus continuously regenerating the catalyst; (e) circulating the catalyst regenerated in step (d) to step (a) and thus resupplying the catalyst to the riser; and (f) cooling, compressing, and separating the propylene mixture, which is a reaction product separated in step (b), and thus producing a propylene product.
Type:
Grant
Filed:
December 4, 2019
Date of Patent:
September 13, 2022
Assignees:
SK GAS CO., LTD., KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY, KOREA NATIONAL UNIVERSITY OF TRANSPORTATION INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventors:
Yong Ki Park, Won Choon Choi, Daesung Park, Hawon Park, Changyeol Song, Deuk Soo Park, Ung Gi Hong, Miyoung Lee, Sungwon Kim, Chaeeun Yeo
Abstract: An embodiment takes the form of a prediction system that obtains a respective indicated similarity of trajectories in each of a plurality of combinations of observed vehicle trajectories. The prediction system, for each of the combinations, calculates a distance between respective intermediate representations, generated by a neural network, of the trajectories in the combination, and performs a training of the neural network based on a calculated loss between the distance and the indicated similarity of the trajectories in the combination. The respective calculated losses converge after performing respective trainings for the combinations.
Type:
Grant
Filed:
August 19, 2019
Date of Patent:
September 13, 2022
Assignee:
TOYOTA RESEARCH INSTITUTE, INC.
Inventors:
Stephen G. McGill, Guy Rosman, Luke S. Fletcher