Abstract: Disclosed are a heterogeneously integrated optical modulator and a manufacturing method thereof. The modulator includes a substrate having a trench, an input waveguide disposed at one side of the trench, an output waveguide disposed at the other side of the trench, a first Mach-Zehnder interferometer including first branch waveguides disposed between the input waveguide and the output waveguide and a heater disposed on one of the first branch waveguides, and second Mach-Zehnder interferometers connected to each of the first branch waveguides.

Abstract: Provided is a grape pericarp extract that exhibits neuronal function modulating effects. The grape pericarp extract comprises 15 mg/g or more of malvidin-3,5-diglucoside in dry mass.

Abstract: The present disclosure relates to methods aimed towards non-invasive targeted genomic and epigenomic sequencing of spatially-defined cellular or subcellular region. More particularly, the present disclosure relates to methods of using photoselection to achieve non-invasive targeted genomic and epigenomic sequencing of spatially-defined cellular or subcellular regions, via the use of light-activated probes.

Abstract: The present invention relates to a method for analyzing a biological sample obtained from a subject, comprising analyzing components contained in a biological sample by an assay using a first molecule selected from the group consisting of a molecule binding to a sugar chain bindable with BC2LCN, a molecule binding to SerpinA3, and a molecule binding to Gal3BP, and a second molecule that is BC2LCN.

Abstract: A wearable patient device is provided that includes one or more sensors. The one or more sensors can record one or both of ECG information or phonocardiographic information. The sensor information can be used to determine the blood pressure of a monitored individual, including on a continuous basis. Blood pressure can be determined using one or both of a determined time to empty or fill one or more heart chambers or first and second blood velocities. Vital sign information can be provided to a monitoring individual, including graphical representations of trend information.

Abstract: Provided is a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof; a pharmaceutical composition for the prevention or treatment of Sirt6-associated diseases, including as an active ingredient, a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof; and a method for treating Sirt6-associated diseases including administering a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof to a subject in need.

Abstract: A method for preparation of a self-cleaning coating solution is provided. The method comprises mixing an aluminium compound with a solution of an ethanol compound to form a solution. Further, the formed solution is subjected to a first magnetic stirring. After the first magnetic stirring a first transparent solution is formed. Further, a stabilizing agent is added to the first transparent solution of the aluminium compound and the ethanol compound. Subsequent to adding the stabilizing agent a translucent solution is formed. Finally, the formed translucent solution is subjected to a second magnetic stirring for forming a homogeneous second transparent solution.

Abstract: An intra prediction method according to the present invention comprises the following steps: performing a directional prediction using at least one of a neighboring pixel of a current block and a left upper corner pixel positioned at a left upper corner of the current block so as to obtain a first prediction value for the current block; obtaining a second prediction value for the current block using the reference sample positioned in the current block; and weighted summing the first prediction value and the second prediction value using a weighting matrix so as to obtain a final prediction value for the current block. According to the present invention, image encoding/decoding efficiency may be improved.

Abstract: The present disclosure provides a modified catalyst, and preparation method and a method for producing aromatic hydrocarbons by aromatization of olefins using the modified catalyst. The modified catalyst comprises an acidic molecular sieve and an olefin aromatization active metal component, the total acid amount of the catalyst as measured by NH3-TPD method is not higher than 0.35mmo1/g, and ratio of the strong acid to weak acid is within a range of 0.8-1.2.

Abstract: The disclosure provides for systems, methods, and compositions for targeting polynucleotides. More particularly, the disclosure provides non-naturally occurring or engineered DNA or RNA-targeting systems comprising a novel DNA or RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA and wherein the CRISPR effector protein is a Cas protein.

Abstract: An antenna apparatus may be disclosed. The antenna apparatus may include a feed network including a plurality of first internal transmission lines arranged in a cross form and a plurality of second internal transmission lines arranged in a ring form around the plurality of first internal transmission lines; and a plurality of radiation elements positioned around the feed network and radiating signals fed by the feed network.

Abstract: Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA.

Abstract: A method of searching a cell in a mobile station of a communication system in which a plurality of cells are grouped into a plurality of cell groups, each cell group including at least two cells, includes: detecting a primary synchronization signal and a secondary synchronization signal from a received signal; and identifying a cell based on a combination of the primary synchronization signal and the secondary synchronization signal. The secondary synchronization signal is related to the cell group to which the mobile station belongs and the primary synchronization signal is related to the cell to which the mobile station belongs within the cell group.

Abstract: There are provided a method for processing an exceptional case of establishing a default bearer and a device therefor in order to solve a problem in that a user equipment cannot actually receive an IP service by accessing a packet network while failing in establishing the default bearer in a mobile communication system. A method for processing an exceptional ease of establishing a default hearer in a mobility management entity includes: receiving a network attachment request from a user equipment; transmitting a network attachment acceptance including an activation request of the default bearer to the user equipment in response to the network attachment request; and cancelling a network attachment procedure when a completion response to the activation request of the default bearer is not received from the user equipment within a predetermined time.

Abstract: Provided are a power brokerage method and a power brokerage system, and the power brokerage system stores encrypted power brokerage and trading information and a digitally signed hash value in a blockchain distributed ledger through a smart contract code running on a blockchain platform and allows the same to be retrieved. Also, the power brokerage system protects sensitive information related to a brokerage trading contract, a bid, and a settlement by allowing a participant participating in the power market to retrieve original data related to power brokerage and trading information from a power trading server and to compare and verify data forgery/falsification and, at the same time, ensures data integrity and transparency of a brokerage contract and trading.

Abstract: Devices, systems, and methods for a treating dementia or Alzheimer's disease in a subject in need thereof. In one example, combined auditory and visual stimuli having a frequency of about 20 Hz to about 60 Hz, and more specifically about 40 Hz, are non-invasively delivered to the subject to induce synchronized gamma oscillations in at least one brain region of the subject. In particular, pursuant to various treatment and exposure protocols, combined auditory and visual stimulation (as opposed to auditory or visual stimulation alone) promotes a microglia response in the medial prefrontal cortex (mPFC). More generally, combined auditory and visual stimulation induces an extended microglia clustering response in the auditory cortex, the visual cortex, and the mPFC.

Abstract: The present disclosure relates to an imaging system and a detection method. The detection method includes the following steps. Receiving, by a processing unit of the image system, multiple recognition label data sets transmitted from multiple terminal devices. Determining a matching degree value between the recognition label data sets and an image data, and obtaining multiple weight values from a storage unit corresponding to the terminal devices. Setting the weight values and the corresponding matching degree values as multiple label points, and classifying the marker points into multiple cluster groups by a clustering algorithm. Calculating a centroid of the largest cluster group. The centroid of the largest cluster group corresponds to a clustering weight value and a clustering matching value. When the clustering weight value or the clustering matching value meets an adjustment condition, adjusting a neural network unit according to the largest cluster group.

Abstract: A platform for a semi-submersible floating type offshore structure according to an exemplary embodiment of the present invention includes a main body which is installed on the sea and has an arrangement structure in which a plurality of pontoons is combined to form a plurality of polygonal shapes; and a protrusion member connecting unit which extends from each corner of the main body and connects a protrusion member outwardly protruding from the main body to the main body.

Abstract: Methods and apparatus for contacting printing via electrostatic force. In one example, an apparatus for contact printing using an ink includes a substrate, a conductive layer disposed on the substrate, and a group of microstructures disposed on the conductive layer. Each microstructure includes a group of conductive porous medium extending from the conductive layer. The apparatus also includes a dielectric layer conformally disposed on the microstructures and configured to electrically insulate the microstructures from the ink during use. The conductive layer is configured to apply a voltage on the group of microstructures to facilitate the loading and dispensing of ink.

Abstract: The present invention relates to a docetaxel albumin nanoparticle pharmaceutical composition, a preparation method therefor, and a use thereof for manufacturing drugs for treating cancer. The pharmaceutical composition comprises docetaxel, albumin and amino acid(s), wherein the weight ratio between albumin and docetaxel is no more than 50, preferably is 20:1 to 1:1, and the weight ratio between amino acid(s) and docetaxel is not less than 0.5, preferably is 1:1 to 20:1.