Abstract: The present disclosure provides antibodies that specifically bind to human glucocorticoid-induced TNFR family related receptor (GITR) and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human GITR and modulate GITR activity, e.g., enhance, activate or induce GITR activity, utilizing such antibodies. The present disclosure also provides methods for treating disorders, such as cancer and infectious diseases, by administering an antibody that specifically binds to human GITR and modulates GITR activity e.g., enhances, activates or induces GITR activity.

Abstract: Provided is a spike neural network circuit. The spike neural network circuit includes an axon configured to generate an input spike signal, a synapse including a first transistor for outputting a current according to a weight and a second transistor connected to the first transistor and outputting the current according to an input spike signal, a neuron configured to compare a value according to the current output from the synapse with a reference value and generate an output spike signal based on a comparison result, and a radiation source attached to a substrate on which the synapse is formed, configured to output radiation particles to the synapse, and configured to increase magnitudes of threshold voltages of the first and second transistors of the synapse.

Abstract: Provided by the present invention is a magnesium-antimony-based (Mg—Sb-based) thermoelement, a preparation method and application thereof. The Mg—Sb-based thermoelement comprises: a substrate layer of a Mg—Sb-based thermoelectric material positioned in the center of the thermoelement, transitional layers that are attached to the two surfaces of the substrate layer, and two electrode layer that are respectively attached to the surfaces of the two transitional layers; the transitional layers are made of a magnesium-copper alloy and/or magnesium-aluminum alloy, and the electrode layer is made of copper. The transitional layer and the electrode layer which are developed in the present invention and which are suitable for a Mg—Sb-based thermoelectric material have great significance and prospects in application. The electrode layer enable the Mg—Sb-based thermoelectric material to have an opportunity to enter the market and realize commercialization.

Abstract: The invention relates to a method for controlling an electrical transmission link (3) between first and second AC voltage buses (11, 21) comprising a high-voltage DC line (320), first and second AC/DC converters (321, 322) connected to the high-voltage DC line (320), comprising: retrieving a setpoint active power value (Pdc0) applied to a converter (321, 322); retrieving the instantaneous values V1 and V2 of the voltages on the first and second buses; wherein the setpoint active power of the first or of the second converter is modified by a value including a term ?Pdc, so as to impose new dynamics on the first and second areas, where: ?Pdc=?Pdcs+?Pdca.

Abstract: Provided is an X-ray tube. The X-ray tube includes a cathode electrode, an anode electrode vertically spaced apart from the cathode electrode, an emitter on the cathode electrode, a gate electrode disposed between the cathode electrode and the anode electrode, the gate electrode including an opening at a position corresponding to the emitter, and a spacer provided between the gate electrode and the anode electrode. The spacer includes an insulator and conductive dopants doped in the insulator.

Abstract: Disclosed herein is a complex generator including a hydrophilic fiber membrane coated with an adsorption material. Electrical energy is generated in such a manner that the adsorption material is adsorbed onto a polar solvent in some region of the hydrophilic fiber membrane by asymmetrical wetting of the polar solvent for the hydrophilic fiber membrane.

Abstract: A washing and desalting device includes a first shell and a plurality of filaments. The first shell has a first receiving cavity and is provided with a liquid inlet and a liquid outlet that communicate with the first receiving cavity. The plurality of the filaments is provided in the first receiving cavity, and the length direction of each of the filaments is consistent with that of the first receiving cavity. The device can be incorporated in a washing and dehydrating system.

Abstract: The present invention discloses a Ziegler-Natta catalyst system for olefin polymerization, comprising at least one compound represented by formula (I) as (i) an internal electron donor, (ii) an external electron donor, or (iii) the both, wherein M1, M2, M3, M4, M5, M6, M1?, M2?, M3?, M4?, M5? and M6? are each independently selected from the group consisting of hydrogen, hydroxy, amino, aldehyde group, carboxy, acyl, halogen atoms, —R1 and —OR2, wherein R1 and R2 are each independently a C1-C10 hydrocarbyl, which is unsubstituted or substituted by a substituent selected from the group consisting of hydroxy, amino, aldehyde group, carboxy, acyl, halogen atoms, C1-C10 alkoxy and heteroatoms; and wherein, when among M1-M6 and M1?-M6?, any two adjacent groups on the same phenyl ring are each independently selected from the group consisting of R1 and —OR2, the two adjacent groups may optionally be linked to form a ring, with a proviso that M1, M2, M3, M4, M5, M6, M1?, M2?, M3?, M4?, M5? and M6? are not simultaneous

Abstract: A medical system comprising: a robotic arm, a control unit configured to issue a control signal, a medical device intended to penetrate an anatomical structure, the medical device being configured to emit a warning signal which varies as a function of a variable electrical characteristic of the anatomical structure, said medical device comprising a body with first and second electrodes, an electric generator suitable for applying at least one measurement electric current between the first and second electrodes, and a processing device suitable for determining a measurement parameter related to the electrical characteristic, based on said at least one measurement electric current, and for emitting the warning signal corresponding to the measurement parameter, wherein the control unit is configured to issue the control signal as a function of the warning signal.

Abstract: Recombinant adenovirus genomes that include an exogenous open reading frame (ORF) and a self-cleaving peptide coding sequence are described. Optimal placement of the exogenous genes for minimal impact on viral kinetics is further disclosed. Therapeutic applications of the recombinant adenoviruses are also described.

Abstract: Disclosed herein is a method for ex vivo expanding tumor-infiltrating lymphocytes for use in adoptive cell therapy (ACT). The method involves culturing tumor fragments from the subject in a culture medium containing IL-2 and a 41BB agonist in an amount effective to expand tumor-infiltrating lymphocytes with enriched tumor-reactivity and specificity. Also disclosed is a method for treating a tumor in a subject that involves treating the subject with nonmyeloablative lymphodepleting chemotherapy, and administering tumor-infiltrating lymphocytes expanded by the disclosed methods.

Abstract: A method of providing a search index based on a Bloom filter in a distributed data sharing environment based a block chain includes generating, by a data generating device, Bloom filters used as the search index on the basis of a hash value calculated by applying a hash function to a keyword set for searching for data which is to be shared, generating, by a block providing server, a new block on the basis of the Bloom filters and the data received from the data generating device and performing proof of work (PoW) on the new block, for adding the new block to the block chain, and distributing, by a block distributing server, block chain data including the new block added to the block chain.

Abstract: A method for motion prediction is provided. The method includes: capturing, by a single camera, a plurality of cameras or 3D software, images of an object at multiple angles to generate multi-view images of the object; synthesizing motion capture (MoCap) data according to the multi-view images; projecting a masking object onto the object to generate multi-view training images, wherein the multi-view training images are images in which parts of limbs of the object are unoccluded and other parts of the limbs of the object are occluded; and using the motion capture data and the multi-view training images to train a predictive model.

Abstract: The invention relates to novel pure organic emitter molecules and optoelectronic devices containing these organic emitter molecules. According to the invention, in the optoelectronic device, after the excitation of an organic molecule, relaxation and intersystem crossing processes also result from the almost isoenergetic charge transfer triplet state (3CT) for the direct rapid occupation and emission of the charge transfer singlet state (1CT), so that a 1CT?S0 fluorescence occurs without a thermal activation.

Abstract: The present disclosure provides a one-time programmable capacitive fuse bit, including an upper plate, the upper plate includes a plurality of fuses arranged side by side and spaced by an internal from each other, middle portions of two adjacent fuses are connected to each other; a connecting portion connected to the fuse is disposed above two ends and the middle portion of each of the plurality of fuses; the fuse bit further includes a lower plate corresponding to the two ends and the middle portion of the fuse, the lower plate is disposed below the fuse; the lower plate corresponding to the middle portion of the fuse is opposite to the connecting portion corresponding to the middle portion of the fuse; a hollow portion is disposed between the lower plate corresponding to the middle portion of the fuse and the lower plate corresponding to both ends of the fuse.

Abstract: A semiconductor device, including: a substrate; a first source/drain layer, a channel layer, and a second source/drain layer sequentially stacked on the substrate and adjacent to each other, and a gate stack formed around an outer circumference of the channel layer; wherein at least one interface structure is formed in at least one of the first source/drain layer and the second source/drain layer, the conduction band energy levels at both sides of the interface structure are different and/or the valence band energy levels are different.

Abstract: A traffic condition prediction system and a traffic condition prediction method are disclosed. The method includes: determining a center of circle in a surveillance image of a target traffic scene; determining a first circle based on the center of circle and a first radius; extracting a plurality of first feature points along the circumference of the first circle according to a first preset sampling frequency; generating a scene feature of the target traffic scene at least based on the first feature points; determining whether the scene feature and a scene feature of another traffic scene are similar; and when determining that they are similar, predicting traffic condition of the target traffic scene through a prediction model used for predicting traffic condition of the other traffic scene. The scene feature of the target traffic scene and that of the other traffic scene are generated in a same way.

Abstract: The present invention relates to the field of natural gas production, and discloses a well structure for natural gas hydrate production, which comprises: a natural gas production well (12); an injection well (4) capable of extending into a geothermal reservoir and injecting a heat-carrying fluid; a curved connecting well (7), the inlet end of the curved connecting well (7) is connected to the outlet end of the injection well (4); a hydrate production horizontal well (10), which may be arranged in a shallow hydrate reservoir (9), the curved connecting well (7) and the hydrate production horizontal well (10) are connected by an ascending well section (8). With the above technical scheme, the high curvature connected well connecting the horizontal well and the vertical well can be located in the bottom layer below the hydrate reservoir, enhancing the stability and production efficiency of the gas hydrate production well.

Abstract: The disclosure proposes a yaw calibration method and system for a wind turbine. The calibration method includes: establishing a cylindrical coordinate graph of wind resource distribution based on historical wind farm operation data, to determine a wind direction interval of main inflow wind conditions of a wind farm; calculating an effective value of active power of each wind speed sub-interval, and obtaining a fitted power curve of each refined interval through curve fitting; and setting an angle between a central axis of a refined interval for a fitted power curve corresponding to a calibration curve in each wind speed range and a central axis of the to-be-calibrated wind direction interval as a yaw error calibration value in the wind speed range, to establish a wind speed-yaw error calibration value lookup table; and determining a yaw error calibration value under a current wind direction and a current wind.

Abstract: Systems and methods in which multi-dimensional metric monitoring is used with respect to multi-wavelength scattering for smoke detection are described. A multi-dimensional metric may dynamically track a slope of a relationship between scattered light of multiple wavelengths of scattered light being monitored. A multi-dimensional metric monitoring smoke detection algorithm may utilize multi-dimensional thresholds with respect to monitoring of the multi-dimensional metric for initiating a fire alarm and resetting the fire alarm. An optical measuring chamber utilized for providing multi-wavelength scattering signals utilized in deriving a multi-dimensional metric for smoke detection may be configured for wide-scattering-angle signal collection, such as using a light trapping sub-chamber having a light-guide diaphragm assembly configured for wide-scattering-angle signal collection.