Abstract: Compositions and methods for inducing and isolating virus-like particles (VLPs), and for allowing real-time assessment of VLP-captured analytes obtained from targeted living mammalian cells, are provided.

Abstract: Disclosed herein are an image encoding/decoding method and apparatus. The image decoding method of the present disclosure may include obtaining maximum transform block size information, deriving a maximum transform block size on the basis of the maximum transform block size information, and, determining ether or not a secondary inverse transform is applied to the current block on the basis of the maximum transform block size and a horizontal size and a vertical size of a current block.

Abstract: The present invention relates to a method and apparatus for transceiving data. A method in which a transmitting terminal transmits data to a receiving terminal in a MIMO system according to one embodiment of the present invention comprises the following steps: generating a data field containing the data; generating a signal field containing information on the data field; generating a data frame containing the data field and the signal field; and transmitting the data frame to the receiving terminal. According to the present invention, an end of the frame being transmitted is accurately notified to the receiving terminal in a communication system in which the frame is transmitted using MIMO, thereby decoding the frame in a more efficient manner at the receiving terminal.

Abstract: The present invention relates to a method for encoding/decoding a video. To this end, the method for decoding a video may include: deriving a spatial merge candidate from at least one of spatial candidate blocks of a current block, deriving a temporal merge candidate from a co-located block of the current block, and generating a prediction block of the current block based on at least one of the derived spatial merge candidate and the derived temporal merge candidate, wherein a reference picture for the temporal merge candidate is selected based on a reference picture list of a current picture including the current block and a reference picture list of a co-located picture including the co-located block.

Abstract: A focused ultrasound device and method for dermatological treatment. The focused ultrasound device includes a focused ultrasound applicator, an automatic motion mechanism, a driver, a computer, a software operation interface. In addition, the focused ultrasound method for dermatological treatment utilizes the same focused ultrasound applicator, to achieve coaxial deep layer and shallow layer ablation treatment of the skin.

Abstract: Provided herein are bifunctional compounds with a moiety (e.g., lenalidomide, thalidomide) that is a binder of an E3 ubiquitin ligase (e.g., Cereblon) and another moiety that is a binder of a target protein (e.g., kinase (e.g., CDK (e.g., CDK9 and/or CDK12))) to induce degradation of the target protein CDK9 and/or CDK12. Also provided are pharmaceutical compositions comprising the bifunctional compounds, and methods of treating and/or preventing diseases (e.g., proliferative diseases, such as cancers (e.g., ovarian cancer, breast cancer, or prostate cancer))). Provided also are methods of inducing the degradation of the target protein (e.g., kinase (e.g., CDK (e.g., CDK9 and/or CDK12))), and methods of inducing apoptosis in a cell in a biological sample or subject by administering the bifunctional compound or composition described herein.

Abstract: A system and method for widening a narrowed blood vessel in a patient, the system including a guidewire, a balloon catheter having an enlarging balloon, and a tubular support sleeve having at least one support balloon. The support balloon is inflated to mechanically support the advancement of the balloon catheter into a narrowed segment of the blood vessel.

Abstract: Methods and compositions using artificial antigen presenting cells in immunotherapy. The artificial antigen presenting cells comprise substrate particles bound to endogenous MHC-peptide complexes obtained from one or more cells. Methods include administering the artificial antigen presenting cells to a patient to activate antigen-specific T cells.

Abstract: One embodiment provides a semiconducting device for at least one of detecting, producing or manipulating electromagnetic radiation having a frequency of at least 100 gigahertz (GHz). The semiconducting device includes a heterodimensional plasmonic structure, and an active layer. The heterodimensional plasmonic structure includes at least one nanostructure configured to form a heterodimensional junction with the active layer and having a tunable resonant plasmon frequency.

Abstract: An integrated boron removal and flocculation process for treating fracturing wastewater is disclosed. The process comprises: adjusting the pH of the fracturing flowback liquid to be treated to become alkaline and adding thereto an oxidant to carry out a reaction for a certain time period, so that the state of the boron present in the liquid is changed; and then adding a barium salt to the resulting reaction mixture to carry out a further reaction between the barium salt and the boron in the changed state to produce a precipitate. The stability of the flowback liquid is deteriorated by the addition of the oxidant. Suspended solids in the flowback liquid can be removed through adsorption, wrapping, and then settling by the action of the precipitate (a barium salt). The process integrates boron removal and flocculation and enables a boron removal rate of 80% or greater. The contents of the suspended solids and oil present in the fracturing flowback liquid after filtration each can be lowered to less than 5.

Abstract: A process for producing a chalcogen-containing compound semiconductor includes providing at least one substrate coated with a precursor for the chalcogen-containing compound semiconductor in a process chamber; heat treating the at least one coated substrate in the process chamber, wherein during a heat treatment, a gas atmosphere comprising at least one gaseous chalcogen compound is provided in the process chamber; removing the gas atmosphere present after the heat treatment of the at least one coated substrate as a waste gas from the process chamber; cooling the waste gas in a gas processor, wherein a plurality of gaseous chalcogen compounds-present in the waste gas after the heat treatment of the at least one coated substrate are separated in time and space from one another from the waste gas by respective conversion into a liquid or solid form. Further provided is a device designed to carry out the process.

Abstract: An androgen receptor (AR) binding molecule has the structure of Formula (I) shown in the following: wherein E and G independently are CH2 or CH, is OH, NH2, OTf or C?C, X is CF3 or trifluorophenyl, and Y and Z independently are CH2 or CH; or is absent, X is CF3, and Y and Z independently are CH2.

Abstract: A digital temperature sensor circuit is disclosed. The digital temperature sensor circuit includes a proportional to the absolute temperature (PTAT) current source, generating a PTAT current proportional to absolute temperature; a sigma-delta modulation module, including an integrator, an analog-to-digital conversion unit, and a feedback digital-to-analog conversion unit; the integrator converts the PTAT current into temperature voltage; the analog-to-digital conversion unit compares the temperature voltage with a band gap reference voltage to generate a digital modulation signal with a duty ratio proportional to the temperature; the feedback digital-to-analog conversion unit adjusts the voltage input by the analog-to-digital conversion unit and controls the charging and discharging speed of the integrator; a digital filter, quantizing the digital modulation signal into a digital signal, and outputting the digital signal.

Abstract: An energy trading system and method for performing energy trading between blockchain-based servers are disclosed. Specifically, in the energy trading method, a blockchain transaction table is divided and operated into an energy channel and a trading channel for energy prosumer power trading, and a procedure for processing a transaction is provided through servers divided into an energy prosumer blockchain server, a power trading blockchain server, and an operator blockchain server.

Abstract: Provided is a hair follicle germ capable of forming a hair shaft-like structure in vitro simply and within a short period of time. A method of producing a hair follicle germ includes: inoculating epithelial cells and mesenchymal cells; maintaining the epithelial cells and the mesenchymal cells in a culture solution in which (a) laminin and entactin, and/or (b) type IV collagen is dispersed; and co-culturing the epithelial cells and the mesenchymal cells in a culture solution to form a hair follicle germ.

Abstract: The present invention provides a nanomechanical sensor unsusceptible to water vapor, due to very low sensitivity to water vapor, that may interfere with measurement. In an embodiment of the present invention, as a sensitive film material of a nanomechanical sensor such as a surface stress sensor, poly(2,6-diphenyl-p-phenylene oxide) is utilized that is used for adsorption/concentration of a substance present in a trace amount in water or air, and represented by Formula (1) wherein n represents an integer of 1 or more. As can be seen from graphs showing changes over time of response signals in a case where a gas to be measured containing acetone, ethanol, and the like and nitrogen are alternately supplied to the surface stress sensor cyclically, it was confirmed that in the sensitive film of the present invention, adsorption/desorption of the components in the gas to be measured significantly occurs in response to the cyclic change, but the sensitivity to water is very low.

Abstract: Disclosed are an optical phased array chip and a method of manufacturing the same. The optical phased array chip includes a plurality of optical switches and a plurality of optical phased arrays implemented on a single integrated circuit, wherein the single integrated circuit includes a silicon substrate, a lower layer formed on an upper portion of the silicon substrate, a silicon layer formed on an upper portion of the lower layer, a first upper layer, a second upper layer and a third upper layer sequentially arranged on the silicon layer, and an electrode that penetrates through the first upper layer while being grounded to the silicon layer and is formed on an upper portion of the first upper layer.

Abstract: A flow field measurement device and a method for a scale model of a natural gas hydrate reservoir are provided. The measurement device includes non-central vertical well pressure sensors, non-central vertical well outlet valves, communicating vessel valves, differential pressure sensors, a communicating vessel, a central vertical well outlet valve, and a central vertical well pressure sensor. By providing differential pressure sensors, between a measuring point of the central vertical well and a measuring point of each of the non-central vertical wells, to measure pressure differences, the flow field measurement device enables a reasonable distribution of a three-dimensional space inside the reactor to analyze gas-liquid flow trends in the reactor with a simulated flow field. Determining whether to turn on the differential pressure sensors according to a predetermination based on a feedback from the pressure sensors, allows flow field measurements in the reactor under both high and low pressure differences.

Abstract: The present invention provides an immunogenic composition comprising, consisting essentially of or consisting of: a) a cell expressing an interferon-? (IFN-?) receptor agonist, and b) a tumour antigen. The invention also provides methods of treatment using said compositions.

Abstract: Disclosed herein is a video decoding method including determining a zero-out width threshold and a zero-out height threshold for distinguishing between a transform coefficient coding region and a zero-out region of a current block according to a size of the current block, determining the transform coefficient coding region and the zero-out region of the current block according to the zero-out width threshold and the zero-out height threshold, acquiring transform coefficient information of the transform coefficient coding region from a bitstream and determining a level of a transform coefficient of the transform coefficient coding region according to the transform coefficient information, determining a level of a transform coefficient of the zero-out region as 0 without acquiring transform coefficient information, and reconstructing the current block by inversely transforming the transform coefficient of the current block.