Patents Assigned to INSTITUTE
  • Publication number: 20220193222
    Abstract: Provided are stable virus formulations that contain at least three amino acids, at least one protein, at least one carbohydrate, and at least one salt. In certain embodiments, amino acid combinations with either at least three, or four, or more amino acids are included. By virtue of inclusion of the amino acids, a virus in the formulations is physically and biologically stable both in liquid and dry powder state. In further embodiments, by virtue of inclusion of the amino acids, a virus in the formulations is physically and biologically stable during lyophilization process. In further embodiments, by virtue of inclusion of the amino acids, a virus in the formulations is physically and biologically stable during storage in both liquid and lyophilized states.
    Type: Application
    Filed: November 30, 2019
    Publication date: June 23, 2022
    Applicant: Vaccine Stabilization Institute
    Inventors: Byeong Seon Chang, Jeong S. Oh
  • Publication number: 20220192166
    Abstract: An object of the present invention is to provide a humanized mouse in which human hematopoietic stem cells can be engrafted for a long term. The present invention relates to a humanized rodent having human neutrophils circulating in a periphery, obtained by transplanting a human hematopoietic stem cell into a human G-CSF gene knock-in rodent, which is an immunodeficient rodent deficient in a G-CSF receptor function by knock-in of a human G-CSF gene at a G-CSF receptor locus, wherein a human G-CSF is expressed and a rodent G-CSF receptor is not expressed.
    Type: Application
    Filed: March 26, 2020
    Publication date: June 23, 2022
    Applicant: CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS
    Inventor: Ryoji ITO
  • Publication number: 20220197225
    Abstract: An ensemble of spin defect centers or other atom-like quantum systems in a solid-state host can be used as a compact alternative for an atomic clock thanks to an architecture that overcomes magnetic and temperature-induced systematics. A polariton-stabilized solid-state spin clock hybridizes a microwave resonator with a magnetic-field-insensitive spin transition within the ground state of a spin defect center (e.g., a nitrogen vacancy center in diamond). Detailed numerical and analytical modeling of this polariton-stabilized solid-state spin clock indicates a potential fractional frequency instability below 10-13 over a 1-second measurement time, assuming present-day experimental parameters. This stability is a significant improvement over the state-of-the-art in miniaturized atomic vapor clocks.
    Type: Application
    Filed: October 18, 2021
    Publication date: June 23, 2022
    Applicant: Massachusetts Institute of Technology
    Inventors: Matthew Edwin TRUSHEIM, Kurt JACOBS, Jonathan HOFFMAN, Donald FAHEY, Dirk Robert ENGLUND
  • Publication number: 20220192589
    Abstract: A finger insert for use with a nailfold imaging device includes a housing to receive the user's finger and an immersion substance (e.g., immersion oil), and a deformable pad that holds the user's finger in place during imaging, as well as prevent bubble formation in the substance. The housing includes a transparent wall to facilitate imaging of the finger. The transparent wall includes multiple angled portions that prevent or reduce contact between the nailfold and the wall, to ensure sufficient blood flow through the nailfold region for imaging.
    Type: Application
    Filed: November 1, 2021
    Publication date: June 23, 2022
    Applicant: Massachusetts Institute of Technology
    Inventor: Ian BUTTERWORTH
  • Publication number: 20220194573
    Abstract: A system and method for controlling a multi-rotor aircraft that implements a number of different lifting rotors that are configured to provide lift to the vehicle. Additionally, each of the lifting rotors have a corresponding yaw control rotor that can help provide yaw control as well as additional sideways movement control.
    Type: Application
    Filed: April 21, 2021
    Publication date: June 23, 2022
    Applicant: California Institute of Technology
    Inventor: Reza Nemovi
  • Publication number: 20220196459
    Abstract: The present disclosure provides a real-time vehicle overload detection method based on a convolutional neural network (CNN). The present disclosure detects a road driving vehicle in real time with a CNN method and a you only look once (YOLO)-V3 detection algorithm, detects the number of wheels to obtain the number of axles, detects a relative wheelbase, compares the number of axles and the relative wheelbase with a national vehicle load standard to obtain a maximum load of the vehicle, and compares the maximum load with an actual load measured by a piezoelectric sensor under the vehicle, thereby implementing real-time vehicle overload detection. The present disclosure has desirable real-time detection, can implement no-parking vehicle overload detection on the road, and avoids potential traffic congestions and road traffic accidents.
    Type: Application
    Filed: September 30, 2021
    Publication date: June 23, 2022
    Applicants: Dibi (Chongqing) Intelligent Technology Research Institute Co., Ltd., Star Institute of Intelligent Systems
    Inventors: Yongduan Song, Yujuan Wang, Gonglin Lu, Shilei Tan, Yating Yang, Chunxu Ren, Mingyang Liu
  • Publication number: 20220200280
    Abstract: A distribution network management system includes a power generation device including a renewable energy power generation source, and is connected to a distribution network through a first node; a first distributed device including a first distributed resource, connected to the distribution network through a second node, and configured to receive first node information and power generation information from the power generation device and attempt to control the first distributed resource so that an overvoltage for the first node is resolved; and a second distributed device including a second distributed resource, connected to the distribution network through a third node which is located farther away from the first node than the second node, and configured to, when the first node information and the power generation information are received from the first distributed device, attempt to control the second distributed resource so that the overvoltage for the first node is resolved.
    Type: Application
    Filed: October 28, 2021
    Publication date: June 23, 2022
    Applicant: Korea Institute of Energy Research
    Inventors: Sea Seung OH, Su-Yong CHAE, Suk In PARK, Gyu Duk KIM, Seung Weon YU
  • Publication number: 20220197823
    Abstract: a method and an apparatus for managing a cache for storing content by determining popularity of the content based on content requests received during a current time slot for the content; transmitting information about the popularity of the content to a time-to-live (TTL) controller and receiving, from the TTL controller, TTL values for each popularity level determined by the TTL controller based on the information about the popularity; and managing the content based on the TTL values for each popularity level are provided.
    Type: Application
    Filed: December 21, 2021
    Publication date: June 23, 2022
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Chunglae CHO, Seungjae SHIN, Seung Hyun YOON, Hong Seok JEON
  • Publication number: 20220193034
    Abstract: Provided herein are compounds useful for the treatment of various parasitic diseases. These compounds, as well as pharmaceutically acceptable salts thereof may be formulated in pharmaceutical compositions, veterinary compositions and may be used in methods of treatment and/or prophylaxis of diseases spread by parasites, including cryptosporidiosis.
    Type: Application
    Filed: April 22, 2020
    Publication date: June 23, 2022
    Applicants: WASHINGTON UNIVERSITY, THE BROAD INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Laurence David Sibley, Bruno Melillo, Eamon Comer
  • Publication number: 20220196549
    Abstract: The disclosure provides a calibration assembly for a scan device. The calibration assembly includes a plurality of light-permeable plates and a reflection plate. The light-permeable plates are different in size, and the light-permeable plates are arranged along thicknesses directions thereof to form a step shape. The light-permeable plates define a plurality of light-permeable areas that respectively have different numbers of layers of the light-permeable plates inversely proportional to transmittances of the light-permeable areas. The light-permeable areas are configured to be permeable to a light having a predetermined frequency. The reflection plate is disposed at a side of one of the light-permeable plates in the thickness direction thereof. The reflection plate has a plurality of first holes having different sizes, and the reflection plate is configured to block the light having the predetermined frequency. The disclosure also provides a calibration system having the calibration assembly.
    Type: Application
    Filed: December 22, 2020
    Publication date: June 23, 2022
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yu-Tai LI, Wei-Yu LIN, Chia-Jen LIN, Chin LIEN, Cho-Fan HSIEH
  • Publication number: 20220198149
    Abstract: A method for machine reading comprehension comprises obtaining question text and article text associated with the question text, generating first knowledge text corresponding to the question text and second knowledge text corresponding to the article text according to a knowledge set, encoding the question text and the article text to generate an original target text code, encoding the first knowledge text and the second knowledge text to generate a knowledge text code, performing a fusion operation on the original target text code and the knowledge text code to introduce part of knowledge in the knowledge set into the original target text code to generate a strengthened target text code, obtaining an answer corresponding to the question text based on the strengthened target text code, and outputting the answer.
    Type: Application
    Filed: December 23, 2020
    Publication date: June 23, 2022
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventor: Xuan-Wei WU
  • Publication number: 20220196542
    Abstract: A structural electronics wireless sensor node is provided that includes layers of electronic components fabricated from patterned nanostructures embedded in an electrically conductive matrix. In some aspects, the structural electronics wireless sensor node includes a plurality of nanostructure layers that each form individual electronic components of the structural electronics wireless sensor node. In certain embodiments, the structural electronics wireless sensor node includes electronic components such as a resistor, a inductor, a capacitor, and/or an antenna.
    Type: Application
    Filed: March 9, 2022
    Publication date: June 23, 2022
    Applicants: Analog Devices, Inc., Massachusetts Institute of Technology
    Inventors: Brian L. Wardle, Yosef Stein, Estelle Cohen, Michael Murray
  • Publication number: 20220194762
    Abstract: A method and a system for controlling a handling machine, and a non-volatile computer readable recording medium are provided. The method includes: analyzing image data to obtain contour data corresponding to a target in the image data; analyzing the contour data to obtain feature data, where the feature data reflects the position of the target in the physical space; and generating control data based on the feature data, where the control data is adapted to control the handling machine to transport the target in response to the position of the target in the physical space.
    Type: Application
    Filed: December 18, 2020
    Publication date: June 23, 2022
    Applicant: Industrial Technology Research Institute
    Inventors: Tsung-Ting Tsai, Carlos Andres Betancourt Baca, Yen-Chung Chang, Ching-Yi Liu
  • Publication number: 20220194817
    Abstract: The present disclosure relates to a device and method for degrading chlorinated hydrocarbon (CHC) in polluted groundwater. A preparation method for each of glass tubes and the method for degrading CHCs are as follows: uniformly mixing 55-85 wt % of Bi2O3, 5-15 wt % of B2O3, and 10-30 wt % of SrCO3, putting into a corrosion resistant crucible, holding at 1,050-1,300° C. for 15-45 min, forming into a glass tube, and holding the glass tube at 200-400° C. for 1-3 h, followed by annealing; soaking the inner wall of the glass tube for 10-30 min with a HCl solution with a concentration of 0.02-0.2 mol/L, washing with water, and providing an ultraviolet lamp to obtain a self-cleaning glass tube; guiding CHC-containing groundwater to the self-cleaning glass tube, turning on the ultraviolet lamp, and carrying out ultraviolet irradiation for 1-8 h, thereby effectively removing the CHCs.
    Type: Application
    Filed: November 27, 2021
    Publication date: June 23, 2022
    Applicants: Shanghai Environmental Engineering Design & Research Institute Co., Ltd., Shanghai Environmental & Sanitary Engineering Design Institute Co., Ltd., Shanghai Jiao Tong University
    Inventors: Lijie SONG, Hui LIU, Guobiao LI, Shanping CHEN, Miao AN, Jun TAI, Ruina ZHANG
  • Publication number: 20220197297
    Abstract: Systems and methods to systematically identify and collect operational vehicle data for selective transmission to a non-local storage location for further analysis and use in training autonomous and semi-autonomous vehicles are provided. The systems and methods provided overcome limitations in storage and transmission of collected data by selectively archiving only that collected driving data warranting further analysis.
    Type: Application
    Filed: March 10, 2022
    Publication date: June 23, 2022
    Applicant: TOYOTA RESEARCH INSTITUTE, INC.
    Inventors: Stephen G. MCGILL, Guy ROSMAN, Luke S. FLETCHER
  • Publication number: 20220201507
    Abstract: A method of managing distributed self-organizing network and base station is disclosed. The base station includes but not limited to a transmitter, a receiver, and a processor coupled to the transmitter and the receiver. The processor is configured at least to: create a management interface for receiving configuration information from surrounding base stations; subscribe the configuration information and store the configuration information into a table; receive, via the receiver through the management interface, the configuration information from a base station of the surrounding base stations; update the table based on the configuration information received from the base station of the surrounding base stations; and execute a distributed self-organizing network (DSON) algorithm comprising one of capacity and coverage optimization (CCO) algorithm, automatic neighbor relation (ANR) algorithm, and physical cell id (PCI) algorithm.
    Type: Application
    Filed: December 23, 2020
    Publication date: June 23, 2022
    Applicant: Industrial Technology Research Institute
    Inventors: Chai-Hien Gan, Yao-Jen Tang, Pi-Chen Chiu
  • Publication number: 20220195308
    Abstract: A hydrothermal liquefaction (HTL) system can comprise a biomass slurry source, a first pump in fluid communication with the slurry source and configured to pressurize a biomass slurry stream from the slurry source to a first pressure, a first heat exchanger in fluid communication with the first pump and configured to heat a slurry stream received from the first pump to a first temperature, a second pump in fluid communication with the first heat exchanger and configured to pressurize a slurry stream received from the first heat exchanger to a second pressure higher than the first pressure, a second heat exchanger in fluid communication with the second pump and configured to heat a slurry stream received from the second pump to a second temperature higher than the first temperature, and a HTL reactor configured to produce biocrude from a slurry stream received from the second heat exchanger.
    Type: Application
    Filed: March 14, 2022
    Publication date: June 23, 2022
    Applicant: Battelle Memorial Institute
    Inventors: Michael R. Thorson, Lesley J. Snowden-Swan, Andrew J. Schmidt, Todd R. Hart, Justin M. Billing, Daniel B. Anderson, Richard T. Hallen
  • Publication number: 20220194460
    Abstract: A multi-part steering apparatus includes an outer rim and an inner hub. The outer rim rotates relative to the inner hub with an adjustable rotation resistance. A rotatable mechanical interface connected the outer rim to the inner hub, and a damper connects to the rotatable mechanical interface. The damper is configured to change the rotation resistance between the outer rim and inner hub. The rotatable mechanical interface may include a gear track disposed on an inside portion of the outer rim and a gear system attached to the inner hub and positioned to mesh with the gear track. The damper may include an electric motor connected to the rotatable mechanical interface and an adjustable load connected to terminals of the electric motor.
    Type: Application
    Filed: December 18, 2020
    Publication date: June 23, 2022
    Applicant: TOYOTA RESEARCH INSTITUTE, INC.
    Inventor: Manuel Ludwig Kuehner
  • Publication number: 20220195964
    Abstract: Electrical propulsion systems and related methods are generally described. In some embodiments, an electrical propulsion system may include an electrically-actuated valve to selectively permit flow of propellant from a reservoir tank to a thruster. The valve may physically isolate the propellant from the thruster when inactivated, exhibiting a non-wetting surface which may inhibit propellant from passing through the valve towards the thrusters. In some embodiments, a valve may be activated through application of a voltage potential to the valve relative to the propellant, which may change the wettability of the valve, permitting propellant to wet and subsequently pass through the valve. The voltage potential may be adjusted to vary the wettability of the valve, resulting in the valve effectively regulating propellant flow rate. The valve may include a conductive layer, a dielectric or insulating layer, and a non-wetting layer to enhance the non-wetting behavior of the valve.
    Type: Application
    Filed: October 20, 2021
    Publication date: June 23, 2022
    Applicant: Massachusetts Institute of Technology
    Inventors: Paulo C. Lozano, Dakota Freeman, Jonathan MacArthur
  • Publication number: 20220197764
    Abstract: Disclosed is a quantum diagnostic circuit, which includes an input unit having an input of at least first to fourth qubits, a diagnostic circuit unit receiving the first to fourth qubits from the input unit and providing a quantum superposition and a quantum entanglement, and an output unit receiving an output of the diagnostic circuit unit and determining whether the output is in a Bell-state, and the diagnostic circuit unit includes a Hadamard gate processing the first qubit to provide the quantum superposition of the first to fourth qubits, a first CNOT gate providing the quantum entanglement between an output of the Hadamard gate and the second qubit, a second CNOT gate providing the quantum entanglement between an output of the first CNOT gate and the third qubit, and a third CNOT gate providing the quantum entanglement between an output of the second CNOT gate and the fourth qubit.
    Type: Application
    Filed: December 3, 2021
    Publication date: June 23, 2022
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: SUNGIK JUN, Kwang-Won KOH, Kang Ho KIM, Changdae KIM, Taehoon KIM