Patents Assigned to Iowa State University Research Foundation, Inc.
  • Publication number: 20180204682
    Abstract: A method of synthesizing a mixed-halide perovskite is disclosed herein. The method includes the steps of mixing a first single-halide perovskite and a second single-halide perovskite to form a solid phase mixture and heating the solid phase mixture at a temperature below a first decomposition temperature of the first single-halide perovskite and below a second decomposition temperature of the second single-halide perovskite for a time sufficient to form the mixed-halide perovskite. During the mixing, the first and second single-halide perovskite are both in the solid phase. A mixed-halide perovskite made according to the method is also disclosed herein. The mixed-halide perovskite is free of amorphous and/or semicrystalline phases. The mixed-halide perovskite can be utilized in a photovoltaic cell in a solar panel.
    Type: Application
    Filed: December 26, 2017
    Publication date: July 19, 2018
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Javier Vela-Becerra, Bryan A. Rosales
  • Patent number: 10022458
    Abstract: Applicants have discovered a novel induction method for inducing digital dermatitis lesions consistent with the natural disease process. Applicants have prepared a consortium including a macerated tissue culture that may be used in the method as well as a novel inoculation procedure. The consortia of microbes includes isolates of Treponema phagedenis, Porphorymonas, and Bacteroides and the invention includes use of these novel isolates in preventing and treating digital dermatitis. The invention can be used to screen, test or compare the relative efficacy of various drugs and biologics for use in treatment or control of digital dermatitis.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: July 17, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Paul Joseph Plummer, Adam Krull, Jan Shearer, Patrick Gorden
  • Patent number: 10007662
    Abstract: A biologically-inspired model for sequence representation, method of construction and application of such models, and systems incorporating same are provided. The model captures the statistical nature of sequences and uses that for sequence encoding, recognition, and recall. The model can be trained in real time, has few tunable parameters, and is highly parallelizable, which ensures that it can scale up to very large problems. Applications of the model to word and speech recognition, machine leaning, robotics, computational bioinformatics, genetics datasets, and other sequence processing pipelines are provided.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: June 26, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Alexander Stoytchev, Volodymyr Sukhoy
  • Patent number: 9988318
    Abstract: This invention relates to bio-renewable fertilizer compositions and methods of making and using the bio-renewable fertilizer compositions. In particular, the fertilizer compositions include biodegradable nutrient carriers, which have naturally derived, bio-renewable nitrogen content. The fertilizer compositions also contain biodegradable stabilizer.
    Type: Grant
    Filed: October 12, 2015
    Date of Patent: June 5, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: James Schrader, William Graves, Jr., David Grewell
  • Publication number: 20180147275
    Abstract: The present invention relates to infectious DNA clones, infectious chimeric DNA clones of porcine circovirus (PCV), vaccines and means of protecting pigs against viral infection or postweaning multisystemic wasting syndrome (PMWS) caused by PCV2. The new chimeric infectious DNA clone and its derived, avirulent chimeric virus are constructed from the nonpathogenic PCV1 in which the immunogenic ORF gene of the pathogenic PCV2 replaces a gene of the nonpathogenic PCV1, preferably in the same position. The chimeric virus advantageously retains the nonpathogenic phenotype of PCV1 but elicits specific immune responses against the pathogenic PCV2. The invention further embraces the immunogenic polypeptide expression products. In addition, the invention encompasses two mutations in the PCV2 immunogenic capsid gene and protein, and the introduction of the ORF2 mutations in the chimeric clones.
    Type: Application
    Filed: January 19, 2018
    Publication date: May 31, 2018
    Applicants: Virginia Tech Intellectual Properties, Inc., Iowa State University Research Foundation, Inc.
    Inventors: Xiang-Jin Meng, Martijn Fenaux, Patrick G. Halbur
  • Publication number: 20180150457
    Abstract: A biologically-inspired model for sequence representation, method of construction and application of such models, and systems incorporating same are provided. The model captures the statistical nature of sequences and uses that for sequence encoding, recognition, and recall. The model can be trained in real time, has few tunable parameters, and is highly parallelizable, which ensures that it can scale up to very large problems. Applications of the model to word and speech recognition, machine leaning, robotics, computational bioinformatics, genetics datasets, and other sequence processing pipelines are provided.
    Type: Application
    Filed: January 9, 2015
    Publication date: May 31, 2018
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Alexander Stoytchev, Volodymyr Sukhoy
  • Patent number: 9981315
    Abstract: A concentric ring gas atomization nozzle with isolated gas supply manifolds is provided for manipulating the close-coupled atomization gas structure to improve the yield of atomized powders.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: May 29, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Joel R. Rieken, Andrew J. Heidloff, Iver E. Anderson
  • Patent number: 9966533
    Abstract: A method of fabricating an organic photovoltaic device. The method includes providing a first electrode which by applying a layer of conductive material onto a transparent substrate. The conductive material forms the first electrode. The method also includes placing an active layer of organic photovoltaic material on top of the first electrode. The active layer is configured to convert photonic energy into electrical energy. Placing an active layer of organic photovoltaic material includes placing an active layer of organic photovoltaic material having ferroelectric dipoles dispersed therein. The method further includes applying a second electrode on top of the active layer of organic photovoltaic material.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: May 8, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Kanwar Singh Nalwa, Sumit Chaudhary
  • Publication number: 20180117352
    Abstract: Provided herein are embodiments of a Quadruple Butterfly Coil (QBC) configuration having enhanced focality for stimulation of specific areas of a brain for therapeutic treatment. Finite element simulations were conducted for the QBC, the QBC with a single shield, and the QBC with a double shield. The stimulation profiles for these coil configurations were assessed with 50 anatomically realistic MRI derived head models. The coils were positioned on the vertex and the scalp over the dorsolateral prefrontal cortex to stimulate the brain. Computer modeling of the coils was performed to determine volume of stimulation, maximum electric field, location of maximum electric field, and area of stimulation across all 50 head models for both coils.
    Type: Application
    Filed: October 26, 2017
    Publication date: May 3, 2018
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Priyam Rastogi, Erik Gordon Lee, Magundappa Ravi L. Hadimani, David C. Jiles
  • Patent number: 9956233
    Abstract: The present invention provides modified metformin compounds, particularly mito-metformin compounds, and pharmaceutical compositions thereof. Methods of using the compounds to provide neuroprotection and in the treatment and/or prevention of neurodegenerative diseases are also described.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: May 1, 2018
    Assignees: Iowa State University Research Foundation, Inc., The Medical College of Wisconsin, Inc.
    Inventors: Anumantha Kanthasamy, Balaraman Kalyanaraman
  • Patent number: 9957218
    Abstract: Various embodiments disclosed relate to isomerization of muconic acid. In various embodiments, the present invention provides a method of forming trans,trans-muconic acid. The method includes heating a starting material composition to form a product composition including trans,trans-muconic acid. The starting material composition includes cis,cis-muconic acid, cis,trans-muconic acid, or a combination thereof. The starting material composition also includes an electrophilic compound, an organic solvent, or a combination thereof.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: May 1, 2018
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Jean-Philippe Tessonnier, Jack M. Carraher, Toni Pfennig, Brent Shanks
  • Patent number: 9957498
    Abstract: The invention relates to a method for photoreleasing a moiety G from a compound of the formula A-G. The methods of the present invention comprise irradiating a composition comprising the compound of the formula A-G at a wavelength of >500 nm, so as to photorelease the moiety G from the moiety A; wherein the moiety A comprises a chromophore and the moiety G comprises an organic compound.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: May 1, 2018
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Arthur Henry Winter, Christie Lynn Beck, Kaitlyn Marie Mahoney, Toshia Renee Albright, Pratik Pran Goswami
  • Patent number: 9932435
    Abstract: The present invention relates to a block copolymer comprising at least one PA block and at least one PB block. The PA block represents a polymer block comprising one or more units of monomer A, and the PB block represents a polymer block comprising one or more units of monomer B. Monomer A is a vinyl, acrylic, diolefin, nitrile, dinitrile, or acrylonitrile monomer. Monomer B is a radically polymerizable plant oil monomer containing one or more triglycerides. The present invention also relates to a method of preparing a thermoplastic block copolymer by radical polymerizing a radically polymerizable monomer with a radically polymerizable plant oil monomer containing one or more triglycerides, in the presence of an initiator and a transition-metal catalyst system to form the thermoplastic block copolymer. The polymerized plant oil-based block copolymers are useful in a variety of applications, such as asphalt modifiers, rubber compositions, adhesives, tires, in the automobile industry, footwear, packaging, etc.
    Type: Grant
    Filed: January 18, 2013
    Date of Patent: April 3, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Eric William Cochran, Ronald Christopher Williams, Nacu Hernandez, Andrew A. Cascione
  • Patent number: 9932549
    Abstract: An algal growth system can include a frame and a flexible sheet material that can have a substantially vertical orientation, where the flexible sheet material can facilitate the growth and attachment of algae, where the flexible sheet material can be supported by the frame.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: April 3, 2018
    Assignees: Gross-Wen Technologies, Inc., Iowa State University Research Foundation, Inc.
    Inventors: Martin Anthony Gross, Zhiyou Wen
  • Patent number: 9926201
    Abstract: A method, apparatus, and system for fabricating buckypaper or similar sheets of nanostructures having relatively high aspect ratios. A dispersion of nanostructures such as nanotubes is subjected to fluid dynamics/forces which promote alignment of their axes of elongation while in suspension in the flow. An agglomeration of better aligned nanostructures is isolated from the carrier fluid into a useable form. In the case of nanotubes, one form is buckypaper. One example of alignment forces is Taylor-Couette flow shear forces. One example of isolation is filtering the flowing dispersion to collect better aligned nanostructures across the filter into a sheet or film. The degree of alignment can produce anisotropic material properties that can be beneficially used in application of the sheet or film.
    Type: Grant
    Filed: July 18, 2014
    Date of Patent: March 27, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Michael R. Kessler, Daniel Vennerberg
  • Patent number: 9926392
    Abstract: The present invention relates to a thermoplastic block copolymer comprising at least one PA block and at least one PB block. The PA block represents a polymer block comprising one or more units of monomer A, and the PB block represents a polymer block comprising one or more units of monomer B. Monomer A is a vinyl, acrylic, diolefin, nitrile, dinitrile, acrylonitrile monomer, a monomer with reactive functionality, or a crosslinking monomer. Monomer B is a radically polymerizable triglyceride or mixtures thereof, typically in the form of a plant or animal oil. The present invention also relates to a method of preparing a thermoplastic block copolymer or novel thermoplastic statistical copolymers by polymerizing a radically polymerizable monomer with a radically polymerizable triglyceride or mixtures thereof via reversible addition-fragmentation chain-transfer polymerization (RAFT), in the presence of an free radical initiator and a chain transfer agent.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: March 27, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Eric W. Cochran, Ronald Christopher Williams, Nacu Hernandez, Andrew Cascione
  • Patent number: 9920145
    Abstract: The present invention relates to tackifier compounds and methods of using the same. In various embodiments, the present invention provides a tackifier compound including independently substituted or unsubstituted fused rings A and B each independently chosen from (C5-C10)cycloalkyl and (C2-C10)heterocyclyl. Fused ring A is substituted with (R1)1-8 and fused ring B is substituted with —(OC(O)R?C(O)R2)1-8. At each occurrence R? is independently chosen from (C2-C10)alkanylene, (C2-C10)alkenylene, (C2-C10)alkynylene, C5-C20(arylene), and (C1-C20)heteroarylene, wherein R? is unsubstituted or substituted. At each occurrence R1 is independently selected from —OH, —OR3, and —OC(O)R?C(O)R2. At each occurrence R2 is independently chosen from —OH, —OR3, —NH2, —NHR3, and —NR32. At each occurrence R3 is independently chosen from (C1-C10)alkanyl, (C2-C10)alkenyl, (C2-C10)alkynyl, C5-C20(aryl), and (C1-C20)heteroaryl, wherein R3 is unsubstituted or substituted.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: March 20, 2018
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Jason Shih-Hao Chen, Michael Richard Kessler, Michael Dennis Zenner
  • Patent number: 9920302
    Abstract: The present invention relates to a vaccine for protecting a piglet against diseases associated with a novel pestivirus. The vaccine commonly includes a pestivirus antigen and, optionally an adjuvant. Methods for protecting pigs against diseases associated with pestivirus, including but not limited to congenital tremors and methods of producing the pestivirus vaccine are also provided.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: March 20, 2018
    Assignees: Boehringer Ingelheim Vetmedica GmbH, Iowa State University Research Foundation, Inc.
    Inventors: Joseph Gilbert Victoria, Abby Rae Patterson, Callie Ann Visek, Arun V. Iyer, Lea Ann Hobbs, Bailey Lauren Arruda, Paulo Henrique Elias Arruda, Drew Robert Magstadt, Kent Jay Schwartz
  • Publication number: 20180076373
    Abstract: Nowotny-Juza phases offer a wide range of potential applications including solar cell and thermoelectric device fabrication. The disclosure presents a solution phase synthesis of the Nowotny-Juza semiconductors LiZnP, LiCdP, and LiZnSb. These samples are phase pure, crystalline, and exhibit particle sizes of around 20 nm.
    Type: Application
    Filed: September 12, 2017
    Publication date: March 15, 2018
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Javier Vela-Becerra, Miles Arthur Burris White, Michelle JoAnn Thompson, Gordon J. Miller
  • Patent number: 9907865
    Abstract: A particle usable as T1 and T2 contrast agents is provided. The particle is a gadolinium silicide (Gd5Si4) particle that is ferromagnetic at temperatures up to 290 K and is less than 2 ?m in diameter. An MRI contrast agent that includes a plurality of gadolinium silicide (Gd5Si4) particles that are less than 1 ?m in diameter is also provided. A method for creating gadolinium silicide (Gd5Si4) particles is also provided. The method includes the steps of providing a Gd5Si4 bulk alloy; grinding the Gd5Si4 bulk alloy into a powder; and milling the Gd5Si4 bulk alloy powder for a time of approximately 20 minutes or less.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: March 6, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Magundappa Ravi L. Hadimani, Shalabh Gupta, Shane Harstad, Vitalij Pecharsky, David C. Jiles