Abstract: A wire is folded at the central part in the longitudinal direction thereof to form a holding member including a first linear portion 17, a return portion 18, and a second linear portion 19. The first linear portion 17 is inserted through a first pipe 13 of a guide member 2 while the second linear portion 19 is inserted through a second pipe 14 thereof. A first operation part 20 and a second operation part 23 are provided at the first linear portion 17 and the second linear portion 19, respectively. The first linear portion 17 and the second linear portion 19 of the holding member 4 are protruded from the distal end of the guide tube 10 to form a loop 3. The second linear portion 19 is protruded from the distal end of the guide tube 10 longer than the first linear portion 17 to change the shape of the loop 3 and to enlarge the loop 3.

Abstract: A communicating member for a medical container contains a plate member 4 having a first opening 5 and a second opening 6, a first connection port 15 including the first opening 5, a plug 9 that obturates the first opening 5 and a first approximately cylindrical member 19 that is in communication with the first opening 5, a second connection port 16 including the second opening 6 and a barrier member 13 that obturates the second opening 6, and a continuous wall 17 disposed on the plate member 4 on the first approximately cylindrical member 19 side and disposed upright on the plate member 4 such that the continuous wall 17 encloses the first opening 5 and the second opening 6 when the plate member is viewed from above; and the first approximately cylindrical member 19 is provided with a first communication part 20 that has an opening on the second opening 6 side.

Abstract: The present invention provides an injection device that includes: a syringe 2 including a barrel 21 including a cylindrical barrel body 21a and a nozzle 21b provided at a front end of the barrel body so as to be communicated with the barrel body, a gasket 23 slidable in the barrel, and a plunger 24 connected with the gasket and capable of being placed into and removed from the barrel through a rear end opening of the barrel; a finger flange 25 provided in the vicinity of the rear end portion of the barrel body and molded integrally with or separately from the barrel body; a holder 3 having an inner diameter that allows the barrel to be inserted in a bore of the holder, attached to the barrel, and including a spiral protrusion 31a formed on the inner surface of a portion of the holder disposed around the nozzle; and an engagement structure capable of keeping a state in which the holder is attached to the barrel and releasing the attachment.

Abstract: A hemodialysis apparatus which controls dialysis conditions. The hemodialysis treatment is carried out under dialysis conditions determined by defining the course of the chronological target blood indication level as a target control line, measuring the blood indication level at each measurement point (controlling point) in the chronological course, calculating the dialysis conditions using the measured blood indication level and the target blood indication level at the next measurement point (controlling point) of the measurement point in the hemodialysis apparatus carrying out hemodialysis treatment by controlling dialysis conditions using blood volume (BV level) or blood volume change as an indication level (hereinafter blood indication level), to attain the target blood indication level at the next measurement point. This apparatus has a simple control mechanism and has little risk of misoperation or out-of-control. An operator can easily handle it and the control can be quickly and precisely carried out.

Abstract: An indwelling needle device includes a shield tube 4a, a flexible outer needle 8 fixed at a front end of the shield tube 4a, a hub 2 movable in a lumen of the shield tube 4a, with an infusion tube 3 being attached to an end thereof, and a rigid inner needle 1 fixed at a front end part of the hub and insertable into a lumen of the outer needle. The hub is provided with a lateral penetration path 2e that penetrates to a lumen of the hub. A space 14 between an outer surface of the hub and an inner surface of the shield tube communicates with a lumen 10 of the hub via the lateral penetration path. A sealing section 2c is provided on the outer surface of the hub, at a position on a rear end side with respect to the lateral penetration path, so as to keep liquid tightness for the space between the hub and the shield tube. Engagement recesses 2b are formed by the outer peripheral surface of the hub, at side wall portions on both sides of the lateral penetration path.

Abstract: An example of the closed-type blood reservoir of the invention is furnished with an outer shell in which a space is formed within its interior, a flexible septum that is interposed between a blood storage chamber shell and a volume adjustment chamber shell and that divides the space into a blood storage chamber for storing blood and a volume adjustment chamber for storing volume adjustment liquid, a blood inlet port, a blood outlet port, and a blood storage chamber air discharge port that are provided in the blood storage chamber shell such that they are in communication with the blood storage chamber, and a volume adjustment liquid port that is provided in the volume adjustment chamber shell such that it is in communication with the volume adjustment chamber, for injecting and ejecting the volume adjustment liquid into and away from the volume adjustment chamber, wherein the blood inlet port and the blood outlet port each are provided tangentially to the inner surface of the blood storage chamber shell such

Abstract: A blood filter device includes: a housing that includes a dome 2 provided with a blood inlet, a filter retaining portion 3 that is positioned below the dome, and a bottom portion 4 provided with a blood outlet; and a filter 8 that is mounted in a cavity of the filter retaining portion and partitions a cavity of the housing into a dome side and a bottom portion side. A sheet-like filter member 8a of the filter forms a plurality of pleats, and ridgelines of the respective pleats traverse the filter retaining portion in parallel respectively.

Abstract: The medical needle device of the present invention includes: a shield 4 including a substantially cylindrical portion 4a; a tube 13; a first hub 2 that is inserted into an inner bore of the shield movably in an axial direction, whose rear end is connected with the tube 3; a rigid needle 1 that is fixed to a front end portion of the first hub; and a hub movement controlling member 14 that is attached to the shield detachably, wherein the hub movement controlling member 14 includes: a stopper portion 14a that can be inserted from the rear end side of the shield into an inner bore of the shield exsertably, and has a front end that can be in contact with the first hub in a state of reaching a movement end on the front end side of the inner bore of the shield; and a holding portion that can maintain a state where a front end of the stopper portion 14a is in contact with the first hub 2 reaching the movement end on the front end side.

Abstract: A flow control apparatus 1 including a tubular outside member 4, a tubular inside member 10 placed in the outside member 4, and a valve member 20 is used. The inside member 10 includes a through-hole 14 passing through a side wall in a thickness direction and a contact portion 11 that is in contact with the outside member 4, which are arranged in that order in a direction from one opening 16 to the other opening 17. The valve member 20 is placed in the opening 17 of the inside member 10. The valve member 20 passes only a fluid supplied at a set pressure or higher in a direction from the one opening 16 to the other opening 17. The outside member 4 is formed so as to form a gap communicating with the through hole 14 between the outside member 4 and the contact portion 11 due to elastic deformation caused by an external force. The gap forms a flow path of a fluid in combination with the through-hole 14.

Abstract: In a heat exchanger including a plurality of tubes 1 through which a first fluid passes, a housing 2 in which the tubes 1 are installed, and sealing members for sealing a second fluid that flows over surfaces of the tubes 1, the housing 2 includes an inlet 4 for introducing the second fluid therein and a first outlet 5 and second outlets 6 for discharging the second fluid, and the sealing members include a first sealing member 3a positioned on one of end sides of the tubes 1, a second sealing member 3b positioned on the other end side of the tubes 1, and a third sealing member 3c positioned between the first and second sealing members 3a and 3b. The third sealing member 3c is provided so that a gap 7 is provided between the first sealing member 3a and the third sealing member 3c while another gap 7 is provided between the second sealing member 3b and the third sealing member 3c, and that a flow path for the second fluid is formed therein. The second outlets 6 are provided so as to be connected to the gaps 7.

Abstract: A long member 2 is covered with one-side coat member 3 and an other-side coat member 4. The one-side coat member 3 is fixed to the long member 2 by a one-side fixing member 15. The other-side coat member 4 is fixed to the long member by an other-side fixing member 20. The inner peripheral face of the one-side fixing member 15 forms a tapered inner face part for introducing body fluid between the one-side coat member 3 and the long member 2. An insertion guiding member 5 is mounted to the tip end part in an insertion direction of the long member 2. A middle part in the insertion direction of the insertion guiding member 5 has a diameter larger than the base end part thereof.

Abstract: Provided is a pressure detection device capable of easy installation and removal of a sensor in/from a diaphragm, measurement of a pressure in a wide rage, and manufacture at a low cost while reducing a size. A sensor part (A) has: a magnet (12) being applied with a load produced by pressing of a diaphragm (8); and a magnet cap (11) covering the magnet (12). The diaphragm (8) has an intra-diaphragm magnetic body (9) buried therein. The intra-diaphragm magnetic body (9) has a protrusion part protruding from the diaphragm (8) so as to be in contact with the magnet (12). The magnet cap (11) has an opening part enabling the protrusion part of the intra-diaphragm magnetic body (9) and the magnet (12) to be joined together.

Abstract: A heat exchange module 12 is formed by stacking pipe groups obtained by fixing a plurality of pipes 1 with use of pipe array holding members 9a to 9d. Flow path forming members 50 are arranged on pipe groups in the uppermost and lowermost layers, and walls 51 and 52 are provided so as to protrude from the outer-side pipe array holding members and the inner-side pipe array holding members. Flow path members 63 are provided between the walls 51 and 52 adjacent to each other so as to allow through holes 53 and 54 to communicate with each other. The heat exchange module 12 is housed in the housing 2, and while rotating the housing 2, a resin material 24 is filled into a space enclosed by the two inner-side pipe array holding members of each pipe group in the housing 2, interstices around the pipes present between an opening 15a of the housing and the outer-side pipe array holding members, and interstices around the pipes present between an opening 15b of the housing and the outer-side pipe array holding members.

Abstract: There are provided a male type connector (1), a protective cap (2), an inner cap (3) that supports a disinfectant-impregnated member therein and is retained in the protective cap, and a female type connector (4) in which an inner cylinder is fixed at an end of an outer cylinder, the inner cylinder including an internal end portion located inside the outer cylinder and an exposed external end portion. The inner cap includes engaging legs at each of which an engaging convexity is formed. A front end portion of the male type connector allows the engaging convexities at the engaging legs to engage therewith from inside. An inner cap retaining portion is formed on an inner wall surface of the protective cap, and a force exerted by the engagement between the inner cap and the male type connector is larger than a force exerted by the inner cap retaining portion to retain the inner cap.

Abstract: The present invention provides antibodies against AGEs derived from carbonyl compounds that are highly reactive with proteins or peptides, and methods of detecting the AGEs derived from the carbonyl compounds. 3,4-dideoxyglucosone-3-ene (3,4-DGE) is allowed to react with proteins, a host animal is immunized with the reaction product thereof, AGEs, and antibodies against the AGEs (anti-AGE antibodies) are isolated from serum recovered from the host animal. These anti-AGE antibodies thus isolated are allowed to react with a sample, and then the antigen-antibody reaction between the AGEs in the sample and the anti-AGE antibodies is detected. Thereby the presence or amount of the AGEs in the sample can be detected.

Abstract: A hemodialysis apparatus that carries out hemodialysis treatment by measuring or calculating the blood volume or its volume change as a blood indication level, and by controlling dialysis conditions according to said target blood indication level, wherein the chronological course of said blood indication level is defined as a target control line, and the primary blood volume (BV0) can be calculated as blood indication level. In the former part of the dialysis operation, the water removal is controlled so that the circulating blood volume in the body approach to the standard blood volume (BV st) with the use of said target control line. After the water removal of the former part of the dialysis operation, when the circulating blood volume in the body attains the standard blood volume (BV st), the latter part of the dialysis operation is started. In said latter part of the dialysis operation, the water removal operation is performed by substantively maintaining said standard blood volume (BV st).

Abstract: A clip which solves a technical problem that the latching of the clip is not easily released by the external force caused by falling, etc., and is easily released when the clip is used. The clip has opposed clipping arms capable of forming an independent and separate space by pressing and holding a clipped object constituted of a flexible hollow member between them. The clip has a latching means on one end of the opposed clipping arm, which has a latching part capable of latching the clipping arms. The clip further has a latching releasing means capable of releasing the latching by an external force headed to an external direction from the clipping arm. The latching means has a supporting point part acting the latching releasing force, added to the latching means by the latching releasing means, to the direction to release the latching of the latching part.

Abstract: A blood purification method that purifies blood taken from a body by blood dialysis or by hemodiafiltration includes the step of changing an osmotic pressure of the blood to an increasing condition until a blood volume (BV level) attains a standard blood volume, in a former part of a blood purification process and the step of maintaining a standard blood volume and periodically changing the osmotic pressure of the blood in a later part of the blood purification process.

Abstract: The configuration of the present invention includes a winged shield that has a cylindrical shield tube and wings linked to a front end side of the shield tube, a hub that is inserted into an inner bore of the shield tube so as to be movable in an axial direction, and a cannula that is mounted to a front end portion of the hub. By engaging a protrusion with a third annular groove, the hub is held with the winged shield in a state where the cannula protrudes for a predetermined length from a front end of the shield tube. In a state where an inward annular protrusion of the shield tube is engaged with a first holding portion, a tip of the cannula can be stored in the shield tube. By engaging the protrusion of a holding mechanism with a first annular groove, the hub is held with the shield tube so as not to be moved within the shield tube.

Abstract: An apparatus for blood dialysis composed at least of a hemodialyzer (a) whereby blood is brought into contact with a dialysate via a semipermeable membrane and thus purified; a blood circulation system (b) composed of a blood circuit in the arterial side whereby blood is taken out from a patient and flown into the hemodialyzer and another blood circuit in the venous side whereby the blood flown out from the hemodialyzer is returned to the patient; a dialysate supplying/discharging system (c) for supplying and discharging the dialysate composed of a dialysate-supply line for supplying the dialysate to the hemodialyzer and a dialysate-discharge line for discharging the dialysate flown out from the hemodialyzer, and a means (d) of controlling the back-filtration speed. Owing to this constitution, individual steps from the preparation of the dialysis (treatment) to the completion of the treatment and the change from a specific step to the next step can be safely, surely and quickly carried out in most cases.